Clinical trials: Carotid Artery Stent
Carotid Artery Stenosis
Smart Nitinol Stent System for the Treatment of Severe Atherosclerotic Carotid Stenosis
To validate the long-term effects of implantation of the self-expanding Smart nitinol stent system for the treatment of severe atherosclerotic carotid stenosis in a 2-year follow-up study of a large patient cohort
- Trial name
- NCT02800174
- Testing
- Smart nitinol stent implantation, antiplatelet drug
- Volunteers
- 103 people
- Sponsor
- Beijing Jishuitan Hospital
Carotid Artery Diseases
Postapproval Trial On Carotid Stenting in Patients With High Risk Vs Standard Risk for Open Carotid Endarterectomy(REAL)
Until the irruption of the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST), carotid stenting (CAS) has been mainly offered to those patients considered at "high risk" for open carotid endarterectomy (CEA)…
- Trial name
- REAL (NCT02750644)
- Volunteers
- 125 people
- Sponsor
- Joaquin de Haro, M.D.
Carotid Stenosis, Cognitive Impairment
Cognitive Improvement After Carotid Stenting in Hyperbaric Oxygen Therapy Trial
The purpose of CARE-HBOT study is to evaluate whether patients with symptomatic severe carotid artery stenosis with cognitive impairment who underwent hyperbaric oxygen therapy plus standard medical treatment after stent…
- Conditions
- Carotid Stenosis, Cognitive Impairment, Hyperbaric Oxygen Therapy, Stent Implantation
- Trial name
- NCT05980195
- Testing
- Hyperbaric oxygen therapy, Standard medical treatment, Risk factor management
- Volunteers
- 90 people
- Sponsor
- Beijing Tiantan Hospital
Disease Management, Diabetes Complications
Determining Rates of Cardiovascular Complications Among Patients of a Managed Diabetes Care Program
The primary objective of this study is to identify whether cardiovascular complication rates are lower in patients who participate in managed diabetes care, in comparison to provincial and national rates.
- Conditions
- Disease Management, Diabetes Complications, Diabetic Vascular Complications, Diabetic Neuropathy
- Trial name
- DECIDE (NCT00498147)
- Testing
- ADEC Program
- Where
- Canada
- Volunteers
- 1,213 people
- Sponsor
- Group Health Centre
Carotid Artery Disease, Carotid Stenosis
Carotid Angioplasty and Stenting Versus Endarterectomy in Asymptomatic Subjects Who Are at Standard Risk for Carotid Endarterectomy With Significant Extracranial Carotid Stenotic Disease (ACT I)
The study is being conducted to demonstrate the non-inferiority of carotid artery stenting (CAS) using the Emboshield® Embolic Protection System with the Xact® Carotid Stent System to carotid endarterectomy (CEA) for the…
- Conditions
- Carotid Artery Disease, Carotid Stenosis, Stroke, Atherosclerosis
- Trial name
- ACT I (NCT00106938)
- Testing
- Carotid artery stenting with filter (interventional), Carotid artery endarterectomy (surgical)
- Where
- 62 sites in United States
- Volunteers
- 1,663 people
- Sponsor
- Abbott Medical Devices
Carotid Artery Stenosis
Safety and Efficacy of Low Dosage of Terazosin in Subjects Undergoing Carotid Artery Stenting
The purpose of this study is to assess the safety and efficacy of low dosage of Terazosin in Carotid Artery Stenting
- Trial name
- TZ-CAS (NCT03195673)
- Testing
- Terazosin, Carotid artery stenting
- Where
- 2 sites in China
- Volunteers
- 160 people
- Sponsor
- Capital Medical University
Carotid Stenosis
A Prospective, Non-Randomized, Evaluation of Low-Risk Patients Undergoing Carotid Stenting With ANgiomax (Bivalirudin)
Prospective, non-randomized, single-center cohort study treating internal carotid artery stenosis using the Xact Carotid Artery Stent and emboshield distal protection system in conjunction with bivalirudin as the procedural…
- Trial name
- NCT01273350
- Testing
- Carotid PTA and stenting
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- SPSI d.b.a Capital Cardiovascular Associates
Heart Disease, Brain Vascular Accident
A Single Center of Carotid Stenting With Distal Protection for the Treatment of Obstructive Carotid Artery Disease
The primary objective of this study is to assess the safety and effectiveness of stenting in the treatment of obstructive carotid artery disease.
- Conditions
- Heart Disease, Brain Vascular Accident, Carotid Artery Disease, Carotid Stenosis
- Trial name
- NCT00178672
- Testing
- Angioguard XP distal protection device, Heart Catheterization -Angioplasty, stenting
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- The University of Texas Health Science Center, Houston
Peripheral Arterial Disease
Clear-Road Trial, Investigating the Efficacy of the RoadSaver Stent
The objective of this clinical investigation is to evaluate the clinical outcome (up to 12 months) of treatment by means of stenting with the RoadSaver (Terumo) in subjects at high risk for carotid endarterectomy requiring…
- Trial name
- NCT02529345
- Testing
- RoadSaver stent
- Where
- 4 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Flanders Medical Research Program
Stroke
Endarterectomy Versus Stenting in Patients With Symptomatic Severe Carotid Stenosis - 2
Carotid stenosis caused by atherosclerosis is a significant risk factor for ischemic stroke, accounting for up to 15% of all strokes and transient ischemic attacks.
- Trial name
- EVA3S-2 (NCT07054060)
- Testing
- carotid endarterectomy, Carotid artery stenting
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Centre Hospitalier St Anne
Carotid Stenosis
Carotid Endarterectomy Versus Carotid Artery Stenting in Asymptomatic Patients
The trial randomise patients with asymptomatic carotid artery narrowing in whom prompt physical intervention is thought to be needed, but there there is still substantial uncertainty shared by patient and doctor about whether…
- Trial name
- ACST-2 (NCT00883402)
- Testing
- CEA, CAS
- Where
- 125 sites in United States, Austria and 30 more
- Volunteers
- 3,638 people
- Sponsor
- University of Oxford
Carotid Artery Disease, Symptomatic Carotid Artery Stenosis
High Coverage CARotid Stenting vs. Medical Management Alone to Prevent EmboliSm From symptomaTic Non-stenotic cARotid Disease (SyNC)
Goal is to analyse the clinical safety and efficacy of the CARESTO® heal Stent within standard clinical routine for the treatment of patients with symptomatic non-stenotic carotid disease (SyNC) and with high-risk plaque features…
- Conditions
- Carotid Artery Disease, Symptomatic Carotid Artery Stenosis, Carotid Artery Stenting, Carotid Plaque Imaging
- Trial name
- CARESTAR (NCT07166731)
- Where
- Germany
- Volunteers
- 536 people
- Sponsor
- Acandis GmbH
Stroke, Carotid Stenosis
Effects of Carotid Stent Design on Cerebral Embolization
The goal of the proposed study is to contrast the relative efficacy of closed-cell stents versus open-cell stents in preventing periprocedural cerebral embolization in high-risk patients with symptomatic and asymptomatic…
- Trial name
- NCT00830232
- Testing
- closed-cell stent (Xact stent), Open-cell stent (Acculink carotid)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Dallas VA Medical Center
Carotid Artery Stenosis
GORE® Embolic Filter in Carotid Stenting for High Risk Surgical Subjects (EMBOLDEN)
Compare the 30-day safety and efficacy of the GORE® Embolic Filter used in conjunction with FDA-approved carotid stents to a performance goal obtained from carotid stent studies utilizing distal embolic protection.
- Trial name
- EMBOLDEN (NCT00766493)
- Testing
- GORE® Embolic Filter
- Volunteers
- 250 people
- Sponsor
- W.L.Gore & Associates
Carotid Stenosis
Remote Ischemic Conditioning Plus Stenting for Symptomatic Carotid Artery Stenosis
Remote ischemic conditioning (RIC) has emerged as a promising non-invasive strategy to protect the brain, with evidence suggesting its benefit in patients with carotid artery stenting (CAS).
- Trial name
- RICSICAS (NCT07412249)
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 300 people
- Sponsor
- General Hospital of Shenyang Military Region
Carotid Stenosis
Role of the Type of Carotid Stent and Cerebral Protection on Cerebral Microembolization During Carotid Artery Stenting. A Randomized Study Comparing Carotid Wallstent vs Roadsaver® Stent and Distal vs Proximal Protection.
Stenting is an alternative to traditional surgery in the treatment of carotid stenosis.The intra and/or postprocedural cerebral embolization remains the most frequent complication.
- Trial name
- NCT02915328
- Testing
- Filterwire EZ™, MO.MA Ultra, Stent Roadsaver®
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Centro Cardiologico Monzino
Carotid Artery Diseases
OPTIMAl Endovascular Exclusion of Consecutive Patient High-risk Carotid Plaque Using the MicroNet Covered Stent
Prospective, multicentric, multispecialty, international, open-label, single arm study using per-protocol intravascular ultrasound [IVUS, 20MHz electronic phase-array transducer] to document the procedure result of an effective…
- Trial name
- OPTIMA (NCT04234854)
- Testing
- Intravascular Utrasound (IVUS) of Carotid Artery after implantation of CGuard stent
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- John Paul II Hospital, Krakow
Cognitive Function in Carotid Stenting
Assessment of Cognitive Function in Patients Undergoing Carotid Artery Stent Placement
To determine the effect of carotid artery stenting, on cognitive function, in patients with high grade carotid artery stenosis
- Trial name
- NCT00919165
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Corewell Health West
Carotid Occlusion Intolerance
Prediction of Carotid Occlusion Intolerance by Transcranial Doppler Evaluation in Patients Undergoing Carotid Artery Stenting With Proximal Flow Arrest Protection System.
The aim of this observational pilot study is to determine whether intolerance of carotid occlusion during carotid artery stenting can be predicted with preprocedural transcranial Doppler evaluation.
- Trial name
- NCT01922609
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- University Hospital, Motol
Carotid Artery Stenosis (Symptomatic and Asymptomatic)
CEST-PROTECT: Proximal Flow Control With a Balloon Guide Catheter Plus Distal Embolic Protection: a Randomised, Open-label Trial Evaluating Cerebral Protection Techniques
This randomized controlled trial aims to evaluate whether a proximal-distal dual cerebral protection strategy can reduce the occurrence of new cerebral ischemic lesions compared with a single cerebral protection strategy in…
- Trial name
- CEST-PROTECT (NCT07841132)
- Testing
- BGC proximal flow control plus distal filter embolic protection device during carotid artery stenting, Single distal filter embolic protection device during carotid artery stenting
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xuanwu Hospital, Beijing