Clinical trials: Carotid Artery Stent
Peripheral Vascular Diseases
Micronet Covered Stent in in Arterial Locations Beyond the Carotid Bifurcation - FLOW-Guard Study
Prospective observational study of MicroNet covered stent implantation in the elevated risk peripheral lesions (high lesion load, thrombus containing, highly calcified). Open-label, non randomized, single arm observational study.
- Trial name
- FLOW-Guard (NCT04461717)
- Testing
- MicroNet covered stent implantation in the increased risk arterial lesions beyond the carotid bifurcation
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- John Paul II Hospital, Krakow
Carotid Artery Disease
Proximal Protection With The Mo.Ma Device During Carotid Stenting
The objective of the ARMOUR study is to evaluate the safety and effectiveness of the Mo.Ma proximal flow blockage cerebral protection device for patients at high surgical risk for carotid endarterectomy who undergo carotid artery…
- Trial name
- ARMOUR (NCT00744523)
- Testing
- Mo.Ma cerebral protection device
- Where
- 2 sites in United States
- Volunteers
- 262 people
- Sponsor
- Medtronic Endovascular
Internal Carotid Artery Stenosis
SONOlysis in Prevention of Brain Infarctions dUring Carotid Stenting and caroTid EndaRterectomy
The aim of the project is to demonstrate a fibrinolytic effect of sonothrombolysis (continual transcranial Doppler monitoring) using 2 MegaHertz (MHz) diagnostic probe on the reduction of risk of brain infarctions due to the…
- Trial name
- SONOBUSTER (NCT01591005)
- Testing
- sonolysis, endarterectomy, carotid stenting
- Where
- Czechia
- Volunteers
- 242 people
- Sponsor
- University Hospital Ostrava
Carotid Stenosis
Platelet Inhibition and Transcranial Doppler (TCD)-Detected Microemboli During and After Carotid Artery Stenting (CAS) in Asymptomatic Patients Prior to Cardiac Surgery
As with coronary artery stenting, activation and embolisation of platelets occurs with carotid artery stenting (CAS). Based on promising data on the use of clopidogrel plus aspirin in coronary stenting this dual antiplatelet…
- Trial name
- IMPACT (NCT01146301)
- Testing
- Clopidogrel
- Where
- Netherlands
- Sponsor
- R&D Cardiologie
Carotid Artery Stenosis (Symptomatic and Asymptomatic)
Evaluation of Balloon Guide Catheter as Proximal Protection During Carotid Artery Stenting (EMBO-PROTECT)
Carotid angioplasty and stenting (CAS) is an effective treatment for carotid artery stenosis but carries a risk of cerebral embolization.
- Trial name
- EMBO-PROTECT (NCT07576790)
- Testing
- balloon guide catheter, No Proximal Protection Group
- Volunteers
- 126 people
- Sponsor
- Instituto de Investigación Marqués de Valdecilla
a Myocardial Infarction, Coronary Artery Bypass Graft Surgery Percutaneous Transluminal Coronary Angioplasty Stent Placement
The Effects of an Intensive Lifestyle Modification Program on Carotid Artery Intima-Media Thickness
The objective of this study is to evaluate the effect of the Ornish Program on cardiovascular disease as measured by the IMT of the common carotid artery, and to compare this effect to outcomes from patients participating in…
- Trial name
- NCT00243581
- Testing
- Dean Ornish Heart Disease Reversing Program
- Sponsor
- SwedishAmerican Health System
Carotid Artery Disease, Carotid Artery Stenosis
Neurological Outcome With Carotid Artery Stenting
The purpose of this study is to determine how well patients undergoing carotid artery angioplasty and/or stent-supported angioplasty for the treatment of carotid artery stenosis will perform on a battery of tests to assess brain…
- Conditions
- Carotid Artery Disease, Carotid Artery Stenosis, Stroke, Transient Ischemic Attack
- Trial name
- CAS (NCT00597974)
- Testing
- Angioplasty, Stent, Neurological and neuropsychological evaluations
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Columbia University
Carotid Artery Disease, Carotid Artery Stenosis
The Gore SCAFFOLD Clinical Study
Evaluate the safety and efficacy of the GORE® Carotid Stent for the treatment of carotid artery stenosis in patients at increased risk for adverse events from carotid endarterectomy
- Trial name
- NCT01901874
- Testing
- Carotid Artery Stenting
- Where
- 2 sites in United States
- Volunteers
- 312 people
- Sponsor
- W.L.Gore & Associates
Carotid Artery Stenosis, Carotid Artery Stenting
CAS for Stenosis With High-risk Features for CEA
The purpose of this prospective, multicenter, single-group target-value study is to evaluate the safety and efficacy of the carotid artery stent system in patients with high-risk features for carotid endarterectomy.
- Trial name
- HeartCare CAS (NCT07370246)
- Testing
- Carotid artery stent system
- Where
- 16 sites in China
- Volunteers
- 212 people
- Sponsor
- Beijing Tiantan Hospital
Carotid Artery Stenosis, Carotid Artery Diseases
Protection Against Emboli During Carotid Artery Stenting Using the Neuroguard IEP System
A prospective, multicenter single-arm, open label study to evaluate the safety and effectiveness of the Neuroguard IEP System for the treatment of carotid artery stenosis in subjects at elevated risk for adverse events following…
- Conditions
- Carotid Artery Stenosis, Carotid Artery Diseases, Carotid Stenosis
- Trial name
- PERFORMANCE II (NCT04201132)
- Testing
- Carotid artery stenting with Neuroguard IEP System
- Where
- 38 sites in United States, Bulgaria and 4 more
- Volunteers
- 305 people
- Sponsor
- Contego Medical, Inc.
Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction
Clinical Impact of Using IMPROVE to Select Patients for Carotid Revascularisation
Narrowing of the carotid artery due to atherosclerosis with an unstable plaque can cause a stroke. Patients with carotid artery disease who have had a TIA or minor stroke and are at high risk of another stroke are often treated…
- Conditions
- Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction, Stroke Ischemic, Atheroscleroses
- Trial name
- IMPROVE (NCT07556887)
- Testing
- IMPROVE Risk Model
- Where
- 10 sites in Netherlands
- Volunteers
- 613 people
- Sponsor
- Maastricht University Medical Center
Carotid Artery Disease
CAPTURE 2 Post-Marketing Registry
The purposes of the registry are: 1) To provide an ongoing post-market surveillance mechanism to document clinical outcomes. 2) To provide additional information that the RX ACCULINK™ and RX ACCUNET™ can be used safely by a wide…
- Trial name
- CAPTURE 2 (NCT00302237)
- Testing
- RX ACCULINK, RX ACCUNET Embolic Protection System
- Where
- United States
- Volunteers
- 6,426 people
- Sponsor
- Abbott Medical Devices
Carotid Artery Disease
SAPPHIRE Worldwide: Stenting and Angioplasty With Protection in Patients At High-Risk for Endarterectomy
The primary objective of this study is to assess the outcomes of stenting with distal protection in the treatment of obstructive carotid artery disease.
- Trial name
- NCT00403078
- Where
- 5 sites in United States
- Volunteers
- 21,008 people
- Sponsor
- Cordis US Corp.
Carotid Artery Stenosis
A Randomized Trial of Carotid Artery Stenting With and Without Cerebral Protection
The primary objective of this study is to evaluate carotid artery stenting (CAS) with and without cerebral protection (CP) to determine if CP improves safety and effectiveness of CAS.
- Trial name
- NCT00177346
- Testing
- CAS with cerebral protection, CAS without cerebral protection
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Pittsburgh
Carotid Artery Stenosis
Balloon Guide Catheter Combined With Filter Protection for Carotid Artery Stenting
This multicenter, randomized, controlled trial evaluates a combined embolic protection strategy during carotid artery stenting (CAS). Carotid artery stenosis is a major cause of stroke.
- Trial name
- ANGEL-BEACON (NCT07247864)
- Testing
- Balloon Guide Catheter, Distal Filter Protection Device
- Where
- China
- Volunteers
- 296 people
- Sponsor
- Beijing Anzhen Hospital
Carotid Artery Stenosis
Ticagrelor Versus Clopidogrel in Carotid Artery Stenting
Patients with symptomatic or asymptomatic carotid stenosis in whom carotid artery stenting is planned are randomised between antiplatelet therapy with ticagrelor plus aspirin or clopidogrel plus aspirin and examined with brain…
- Trial name
- PRECISE-MRI (NCT02677545)
- Testing
- Ticagrelor, Clopidogrel, Aspirin
- Where
- 15 sites in Belgium, Germany and 4 more
- Volunteers
- 210 people
- Sponsor
- University Hospital, Basel, Switzerland