Clinical trials: Carotid Atherosclerotic Plaques
Atherosclerosis of Artery, Metabolic Syndrome
Carotid Atherosclerotic Plaque Load and Neck Circumference
The aim of this study is to establish a deep learning model to automatically detect the presence and scoring of carotid plaques in neck CTA images, and to determine whether this model is compatible with manual interpretations.
- Conditions
- Atherosclerosis of Artery, Metabolic Syndrome, Machine Learning
- Trial name
- NCT05040958
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Carotid Atherosclerosis, Stroke
Diagnosis and Therapy of Vulnerable Atherosclerotic Plaque
The aim of the present study is to examine the atherosclerotic plaque stability using in vivo and in vitro techniques and to investigate the influence of exercise, anti-diabetic, lipid-lowering and cannabinoids receptor…
- Conditions
- Carotid Atherosclerosis, Stroke, Type 2 Diabetes, Metabolic Syndrome
- Trial name
- NCT00636766
- Testing
- atorvastatin, rimonabant, rosiglitazone
- Where
- Greece
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Atherosclerotic Disease, Plaque, Atherosclerotic
Natural History of Carotid Plaque as Determined by 3D Ultrasound
This proposed follow-up study aims to recruit participants from the original BioImage cohort for a one-time follow-up examination.
- Conditions
- Atherosclerotic Disease, Plaque, Atherosclerotic, Heart Diseases, Stroke
- Trial name
- BioImage2 (NCT03314818)
- Testing
- Ultrasound 3D Imaging
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Pieter Muntendam
Atherosclerosis, Carotid Stenosis
Investigation of Plaque Instability Using Bevacizumab-800CW and MSOT
Determining whether we could visualize uptake of the fluorescent tracer Bevacizumab-800CW, targeting VEGF-A in atherosclerotic plaques by using the new imaging technique Multispectral Optoacoustic Tomography both in- and ex vivo.
- Conditions
- Atherosclerosis, Carotid Stenosis, Fluorescence
- Trial name
- Carotid (NCT03757507)
- Testing
- MultiSpectral Optoacoustic Tomography
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- G.M. van Dam
Atherosclerosis of Artery
Screening for Atherotic Plaques by Ultrasound for Assessing Cardiovascular Risk
Cardiovascular disease is a common diagnosed and treated condition in private practices of primary health care. There is growing evidence that atherosclerotic plaques as predictors for stroke and heart attack are more prevalent…
- Trial name
- NCT03499496
- Testing
- ultrasound guided detection of atherosclerotic plaques
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cabinet de Medecine Interne Générale Demetrio Pitarch
Atherosclerosis, Inflammatory Activity in Carotid Arteries
Effects of Crestor on Inflammation of Atherosclerotic Plaques
The primary aim of this study is to investigate the effect of 40 mg dose of rosuvastatin on carotid plaque inflammation measured with MRI and PET scanning, to evaluate whether these techniques are promising for future proof of…
- Trial name
- NCT00689416
- Testing
- rosuvastatin
- Where
- Sweden
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Carotid Artery Disease, Atherosclerosis
Telerobotic Ultrasound for Carotid Imaging - Feasibility Study
In this proposal, the investigators will demonstrate the feasibility and noninferiority of telerobotic ultrasonography as compared to traditional manual acquisition in performing a limited carotid Duplex examination and in…
- Conditions
- Carotid Artery Disease, Atherosclerosis, Atheromatous Plaques, Arteriosclerosis
- Trial name
- NCT05654935
- Testing
- Ultrasound for Carotid Arteries, Telerobotic Ultrasound for Carotid Arteries
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Cardiovascular Diseases, Fatty Liver
Ultrasound Assessment of Atherosclerotic Plaque Burden and Cardiovascular Risk: A 10-Year Prospective Study
The P-SONAR study is a large, observational, prospective cohort study. The overall aim of the study is to investigate whether plaque burden estimation by 2D ultrasound of the carotid and femoral arteries may enhance…
- Conditions
- Cardiovascular Diseases, Fatty Liver, Atherosclerosis of Femoral Artery, Carotid Artery Plaque
- Trial name
- P-SONAR (NCT06933745)
- Where
- Norway
- Volunteers
- 21,029 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Carotid Artery Plaque, Carotid Web
Atherosclerotic Plaque Characteristics Associated With a Progression Rate of the Plaque in Carotids and a Risk of Stroke
Atherosclerosis is the most common cause of stroke. The aims of the project are to compare the visual and digital analysis of sonographic images of atherosclerotic plaque in carotids in vivo, in vitro and with a histological…
- Trial name
- ANTIQUE (NCT02360137)
- Where
- Czechia
- Volunteers
- 1,863 people, healthy volunteers welcome
- Sponsor
- University Hospital Ostrava
Carotid Artery Plaque
99mTc-rhAnnexin V-128 Imaging for Carotid Atherosclerosis
This was a single-center, single-dose, study comprising a Proof of Concept (PoC) part and a subsequent Phase II part. The study was being done to assess the ability of the radiotracer 99mTc-rhAnnexin V-128 to image…
- Trial name
- NCT02667457
- Testing
- 99mTc-rhAnnexin V-128
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Advanced Accelerator Applications
Atherosclerosis, Atheroma of Cerebral Arteries
Normal Parameters of Cranial Vessels Using Cranial Vascular Duplex Among Egyptian Population
the study will be carried out to standardize normal parameters of vascular duplex ultrasound of the cranial vessels in the Egyptian population.
- Conditions
- Atherosclerosis, Atheroma of Cerebral Arteries, Atheroma; Carotid Artery, Atheroma; Cerebral
- Trial name
- NCT03252652
- Testing
- vascular duplex ultrasound imaging
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Atherosclerosis of Artery
microRNAs in the Diagnosis of Atherosclerotic Plaque Instability
It's a non-randomized, intervention, prospective, single-center study. The aim of the work is to identify of biomarkers of unstable atherosclerosis in brachiocephalic arteries Tasks: identify microRNAs, the expression of which is…
- Trial name
- NCT05680935
- Testing
- blood microRNA, plaque and intima microRNA, histological examination of the plaque
- Where
- Russia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University