Clinical trials: Carotid Disease
Chronic Kidney Diseases, Dialysis; Complications
Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio to Predict Carotid Intima-Media Thickness in Chronic Kidney Disease Patients
This study aims to determine whether the neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) can be used as predictors of coronary heart disease (CHD) in CKD patients undergoing dialysis at Moewardi General…
- Conditions
- Chronic Kidney Diseases, Dialysis; Complications, Coronary Heart Disease
- Trial name
- NCT05472805
- Where
- Indonesia
- Volunteers
- 72 people
- Sponsor
- Universitas Sebelas Maret
Hypertension
Blood Pressure Follow-up Study in Two Chinese Cohorts(C-BPCS)
Essential hypertension is a complex trait which results from interaction between environmental factors and genetic factors. The aim of this study is to investigate the effects of interaction between environmental factors and…
- Trial name
- C-BPCS (NCT02734472)
- Testing
- Incidence and risk factors of hypertension
- Where
- China
- Volunteers
- 5,298 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Carotid Stenosis
Cognitive Outcome After Carotid Surgery
The purpose of this study is to understand how carotid endarterectomy (CEA) or percutaneous carotid angioplasty and stenting (CAS) affect memory and thinking resulting in improving or worsening of thinking or memory.
- Trial name
- NCT02118233
- Where
- 3 sites in United States
- Volunteers
- 56 people
- Sponsor
- Lahey Clinic
Acute Kidney Injury
Carotid Doppler and IVC Measurements for Volume Guided Management in Acute Kidney Injury Patients
1. Evaluate Inferior Vena Cava Indices (Diameters , IVC-CI)\&carotid doppler measurements (corrected Carotid Flow Time ,Carotid Blood Flow ,Carotid Artery Peak Velocity Variations) as Non-Invasive Technique for volume guided…
- Trial name
- NCT05938049
- Testing
- IVC ultrasound & Carotid doppler
- Volunteers
- 60 people
- Sponsor
- Assiut University
Psoriatic Arthritis, Atherosclerosis
PsA T2T Statin Trial on Carotid and Coronary Atherosclerosis
Psoriatic arthritis (PsA) is a chronic inflammatory disease associated with an increased risk of myocardial infarction (MI). Using coronary computer tomography angiogram (CCTA), it is found that a significantly higher prevalence…
- Trial name
- NCT04176978
- Testing
- Rosuvastatin, Treat-to-target strategy
- Where
- Hong Kong
- Sponsor
- Chinese University of Hong Kong
Coronary Arteriosclerosis
Association Between Carotid Plaque Length and Cardiovascular Events
This multicenter study involved 5 hospitals (Changhai Hospital; Yueyang Hospital of Shanghai University of Traditional Chinese Medicine; Gongli Hospital; Putuo Hospital of Shanghai University of Traditional Chinese Medicine; No.
- Trial name
- NCT05159804
- Where
- 5 sites in China
- Volunteers
- 3,637 people
- Sponsor
- Changhai Hospital
Moyamoya Disease, Moyamoya Syndrome
Evaluating Antiplatelet and Physical Therapy for Slowing Progression in Mild Moyamoya Disease.
Moyamoya disease (MMD) is a chronic occlusive cerebrovascular disease characterized by progressive stenosis or occlusion at the terminal portion of the internal carotid artery, with formation of an abnormal vascular network at…
- Conditions
- Moyamoya Disease, Moyamoya Syndrome, Aspirin, Remote Ischemic Conditioning
- Trial name
- MOUNT-EASE (NCT07762547)
- Testing
- aspirin treatment, Remote Ischemic Conditioning
- Where
- China
- Volunteers
- 724 people
- Sponsor
- Beijing Tiantan Hospital
Renal Insufficiency, Chronic
Omega 3 Fatty Acids in Patients With Chronic Renal Disease
To study the tolerance and efficacy of an omega 3 fatty acids supplement on renal and vascular function and inflammatory parameters in patients with chronic renal disease
- Trial name
- NCT03280615
- Testing
- Omega 3 fatty acids, Corn oil
- Where
- Chile
- Volunteers
- 100 people
- Sponsor
- University of Chile
Carotid Stenosis, Optical Coherence Tomography (OCT)
Endovascular Treatment of Cerebrovascular Diseases Guided by Optical Coherence Tomography (OCT) Technology(CVD-OCT)
OCT techniques have been used in the assessment of both intracranial and extracranial lesions.(1) Preprocedural evaluation: The morphologic characteristics of carotid atherosclerotic plaques can be evaluated by OCT before surgery…
- Conditions
- Carotid Stenosis, Optical Coherence Tomography (OCT), Endovascular Treatment
- Trial name
- (CVD-OCT) (NCT06986330)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Cardiovascular Diseases, Myocardial Ischemia
Cohort Study of Heart Rate Variability
To examine factors affecting heart rate variability (HRV) and the role of HRV in heart disease. Specifically, to examine the role of HRV: as a predictor of fatal and nonfatal ischemic heart disease over a six year follow-up of…
- Conditions
- Cardiovascular Diseases, Myocardial Ischemia, Carotid Stenosis, Hypertension
- Trial name
- NCT00005399
- Testing
- No interventions
- Volunteers
- 111,654 people
- Sponsor
- University of North Carolina, Chapel Hill
Moyamoya Disease, Magnetic Resonance Imaging
Predicative Value of Multimodal MRI in Moyamoya Disease
Moyamoya disease (MMD) is a nonatherosclerotic cerebrovascular abnormality, characterized by a progressive stenosis or occlusion of the intracranial internal carotid arteries (ICAs) and their proximal branches, with subsequent…
- Trial name
- NCT03785171
- Testing
- surgical revascularization
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
Cerebrovascular Disorders
Neuroprotective and Cardioprotective Effects Of Palm Vitamin E Tocotrienols
The purpose of the study is to assess the neuroprotective, anti atherogenic and hepatoprotective properties of tocotrienols (palm vitamin E) supplementation as determined by white matter lesion load on serial magnetic resonance…
- Trial name
- NCT00753532
- Where
- Malaysia
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Carotid Stenosis, Femoral Arterial Stenosis
Use of Amplified Sound Signal to Identify Presence of Carotid and Femoral Stenosis
The purpose of the study is to test a new amplified stethoscope(AudioDoc) that can detect the presence of bruit by using an acoustic signal to represent the bruit.
- Conditions
- Carotid Stenosis, Femoral Arterial Stenosis, Carotid Bruit Asymptomatic, Carotid Murmur
- Trial name
- NCT01599195
- Testing
- AudioDoc
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Albert Einstein Healthcare Network
Aneurysm, Intracranial
China Surpass Streamline Post-Market Study
A multi-center, prospective, single-arm, non-randomized, post-market, observational study. The primary objective of this study is to evaluate the long-term safety and efficacy of the Surpass Streamline Flow Diverter System (FDS)…
- Trial name
- NCT05544045
- Testing
- Surpass Streamline Flow Diverter System
- Where
- 15 sites in China
- Volunteers
- 11 people
- Sponsor
- Stryker Neurovascular
Carotid Stenosis
Risk Prediction Model for Cerebrovascular Events in Carotid Artery Stenosis
Atherosclerotic carotid artery stenosis is a major cause of stroke, and early identification of high-risk patients combined with surgical intervention can significantly reduce stroke risk.
- Trial name
- NCT06452173
- Testing
- Plasma, carotid high-resolution magnetic resonance imaging
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Beijing Tiantan Hospital
Intra-operative Hypotension, Carotid Stenosis
Effect of Blood Pressure on rSO2 in Carotid Endarterectomy (CEA)
Carotid endarterectomy (CEA) is the recommended treatment for symptomatic high degree stenosis of the internal carotid artery (ICA).
- Trial name
- NCT01451294
- Testing
- Administration of phenylephrine, Administration of ephedrine
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- G.J. de Borst
Pre Diabetes, Exercise
The Effect of Exercise and Metformin on Carotid Intima-media Thickness in Patients With Prediabetes
The aim of this study is to evaluate whether there is a change in carotid intima media thickness with the application of guide-based exercise programs in individuals with prediabetes, and to evaluate whether there is a difference…
- Conditions
- Pre Diabetes, Exercise, Metformin, Atherosclerosis
- Trial name
- NCT05052918
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Atherosclerotic Disease, Carotid, Carotid Endarterectomy
Evaluate the Precision of ABL-101 Perfluorocarbon and Fluorine-19 MRI for the Mapping of Atherosclerotic Plaque Composition and Inflammation in Patients Undergoing Carotid Endarterectomy
This study is aimed at patients suffering from carotid atherosclerosis. In the presence of atherosclerosis of the carotid arteries, one of the treatments that can be proposed is carotid endarterectomy, the aim of which is to…
- Trial name
- PARFUME (NCT06850324)
- Testing
- ABL-101 is administered at 3mL/kg body weight (to a notional maximum of 100kg, rounded to the nearest ml), at the rate of 15 mL/min (900ml/hour).
- Where
- Switzerland
- Volunteers
- 18 people
- Sponsor
- Ruud van Heeswijk
Diabetes, Hyperlipidemia
Diabetic Under 70 (Diabetics Below 70)
A screening project of diabetics with a very high cardiovascular risk (e.g. diabetes plus coronary heart disease) who already receive cholesterol-lowering therapy.
- Conditions
- Diabetes, Hyperlipidemia, Atherosclerosis
- Trial name
- NCT00516204
- Where
- Austria
- Volunteers
- 685 people
- Sponsor
- AstraZeneca
Stroke (CVA) or TIA, Headache, Migraine
Onabotulinum Toxin A (Botox) for the Treatment of Persistent Post-Stroke and Vascular Headache
Post stroke headache occurs in approximately 10-23% of all stroke patients. Its onset is shortly after experiencing a stroke, or stroke like event, and persists for at least three months.
- Conditions
- Stroke (CVA) or TIA, Headache, Migraine, Botulinum Toxins, Type A, Cerebral Venous Sinus Thrombosis
- Trial name
- NCT04580238
- Testing
- Botox 200 UNT Injection, Non Botox based Standard of Care Treatments for Headache/Migraine
- Where
- Canada
- Sponsor
- University of Alberta
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