Clinical trials: Carotid Occlusion
Carotid Artery Plaque, Ankylosing Spondylitis
Effects of Rosuvastatin on Carotid Artery Plaques in Patients With Inflammatory Joint Disease
Patients with rheumatoid Arthritis (RA) and Ankylosing Spondylitis (AS) are at greater risk of developing cardiovascular disease.
- Conditions
- Carotid Artery Plaque, Ankylosing Spondylitis, Rheumatoid Arthritis
- Trial name
- RORAAS (NCT01389388)
- Testing
- Rosuvastatin
- Where
- Norway
- Volunteers
- 114 people
- Sponsor
- Diakonhjemmet Hospital
Carotid Artery Stenosis
Effect of Evolocumab on Carotid Plaque Composition in Asymptomatic Carotid Artery Stenosis (EVOCAR-1)
This is a phase IV, randomised, placebo-controlled, double-blind, parallel group study to determine the effect of Evolocumab treatment on carotid plaque morphology and composition in asymptomatic patients with >50% carotid artery…
- Trial name
- EVOCAR-1 (NCT03931161)
- Testing
- Evolocumab Auto-Injector [Repatha]
- Where
- United Kingdom
- Volunteers
- 33 people
- Sponsor
- Imperial College Healthcare NHS Trust
Hypertension Arterial, Desaturation
Dexmedetomidine During Carotid Endarterectomy: a Registry on Safety and Satisfaction of Patients and Operators (DexTEA)
From an anesthesiological perspective, carotid endarterectomy (CEA) is an operation that is increasingly being performed with locoregional techniques and sedation.
- Conditions
- Hypertension Arterial, Desaturation, Bradycardia, Surgery (Major Vascular)
- Trial name
- NCT07105527
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Saint Camillus International University of Health Sciences
Acute Ischemic Stroke
Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial
The primary objective is to establish the efficacy of intra-arterial (IA) mechanical thrombectomy (MT) with extracranial proximal carotid artery acute stenting versus non-stenting approaches in patients with acute ischemic stroke…
- Trial name
- PICASSO (NCT05611242)
- Testing
- MT+CAS with IV-AP, MT+CAS with PO-AP, MT+CAT with PO-AP
- Where
- 60 sites in United States
- Volunteers
- 404 people
- Sponsor
- Mercy Health Ohio
Carotid Artery Stenosis, Cerebral Infarction
Bacteria in Atherosclerotic Plaques and Adverse Events
This study is a prospective, multicenter cohort study conducted in western China. The registry study is primarily conducted at the Department of Neurosurgery, Tangdu Hospital, with participation from the Departments of…
- Conditions
- Carotid Artery Stenosis, Cerebral Infarction, Diabetes, Bacteria
- Trial name
- NCT06935279
- Testing
- Carotid Endarterectomy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tang-Du Hospital
Hyperlipidemias, Atherosclerosis
Percentage of Secondary Prevention Patients Treated to Their LDL-C Targets
A cholesterol/lipid profile screening project of high risk patients with hyperlipidaemia (secondary prevention) who already receive cholesterol-lowering therapy.
- Conditions
- Hyperlipidemias, Atherosclerosis, Coronary Heart Disease, Carotid Stenosis
- Trial name
- NCT00536796
- Where
- Austria
- Volunteers
- 1,096 people
- Sponsor
- AstraZeneca
Carotid Stenosis
Carotid Atherosclerosis : Innovative Imaging Biomarkers. Study Case-control
Cerebrovascular accident (CVA) constitutes a major health public problem. This represents the second cardiovascular death cause. CVA is ischemic in 80% of cases.
- Trial name
- ACABII (NCT02748941)
- Testing
- HITS quantification, Ultrasound examinations, High Resolution MRI
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Hospices Civils de Lyon
Atherosclerosis, Cardiovascular Diseases
Prevalence & Progression of Subclinical Atherosclerosis
To evaluate subclinical atherosclerotic disease in menopausal women.
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Coronary Arteriosclerosis, Carotid Artery Diseases
- Trial name
- NCT00006503
- Sponsor
- Rush University Medical Center
Ischemia, Cerebral, Ischemic Stroke
Detection of Cerebral Ischemia With Artificial Intelligence.
In patients undergoing planned surgery for carotid tromendarterendectomy, a non-invasive device that registers heart rate variability is attached.
- Conditions
- Ischemia, Cerebral, Ischemic Stroke, Artery Occlusion, Artery Carotid Stenosi
- Trial name
- CIDAI-BAS (NCT03919370)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Linda Block
Carotid Artery Plaque
The Evaluation of Tomographic 3D Ultrasound for the Assessment of Vascular Pathology
This study concentrates on providing more ultrasound image details when scanning vascular system including arterial and venous systems. A new sensor which provides 3D images is newly designed.
- Trial name
- NCT04318171
- Testing
- 3D Imaging.
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Atherosclerosis, Stroke
Carotid Revascularization Endarterectomy Versus Stenting Trial
The purpose of the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) is to compare the relatively new procedure of stent-assisted carotid angioplasty (CAS) to the traditional and accepted surgical approach of…
- Conditions
- Atherosclerosis, Stroke, Carotid Stenosis, Cerebral Infarction
- Trial name
- CREST (NCT00004732)
- Testing
- Carotid Endarterectomy (CEA), Carotid Artery Stenting (CAS)
- Where
- 115 sites in United States, Canada
- Volunteers
- 2,502 people
- Sponsor
- Rutgers, The State University of New Jersey
Internal Carotid Artery Stenosis, Cognitive Impairment
Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Hemodynamics (CREST-H)
We aim to determine whether cognitive impairment attributable to cerebral hemodynamic impairment in patients with high-grade asymptomatic carotid artery stenosis is reversible with restoration of flow.
- Trial name
- CREST-H (NCT03121209)
- Testing
- Revascularization, Intensive Medical Management (IMM) alone
- Where
- 58 sites in United States, Canada
- Volunteers
- 392 people
- Sponsor
- Columbia University
Atherosclerotic Disease, Carotid
SmartRisk Stroke Prediction by MRI of Carotid Disease
Atherosclerotic plaque at the carotid artery bifurcation is a major source of stroke. The purpose of this investigation is to determine the ability of the SmartRisk software module to predict stroke or stroke-related events due…
- Trial name
- SmartRisk (NCT00860184)
- Where
- 15 sites in United States
- Volunteers
- 300 people
- Sponsor
- VPDiagnostics
Left Main Coronary Artery Disease, Left Anterior Descending Coronary Artery Stenosis
Prospective Evaluation for Hybrid Cardiac Procedures
Multidisciplinary team-approach in order to offer personalized treatments represents the emerging mainstream in cardiovascular medicine.
- Conditions
- Left Main Coronary Artery Disease, Left Anterior Descending Coronary Artery Stenosis, Valve Disease, Heart, Carotid Stenosis
- Trial name
- PERHAPS (NCT05143671)
- Testing
- Coronary artery bypass grafting, Percutaneous coronary intervention, Surgical valve replacement
- Where
- Italy
- Volunteers
- 134 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Carotid Artery Stenosis, Abdominal Aortic Aneurysm
Prevalence of Carotid Artery Stenosis and Abdominal Aortic Aneurysms in Brussels: a Population-based Screening Study.
Both abdominal aortic aneurysm (AAA) and carotid artery stenosis (CAS) are frequent clinical entities, with major morbidity and mortality.
- Conditions
- Carotid Artery Stenosis, Abdominal Aortic Aneurysm, Epidemiology
- Trial name
- NCT04098523
- Testing
- Duplex ultrasound
- Where
- Belgium
- Volunteers
- 3,286 people, healthy volunteers welcome
- Sponsor
- Erik Debing
Carotid Stenosis, Carotid Artery Plaque
CARotid Mri of Atherosclerosis
In the entire world most people die from cardiovascular disease. Death is primarily from myocardial infarction (MI) and stroke which are most often caused by rupture of atherosclerotic plaques. Patients with high-grade, i.e.
- Conditions
- Carotid Stenosis, Carotid Artery Plaque, Carotid Atherosclerosis
- Trial name
- CARMA (NCT04835571)
- Testing
- Optimization of cardiovascular risk management
- Volunteers
- 52 people
- Sponsor
- Linkoeping University
Carotid Occlusion Intolerance
Prediction of Carotid Occlusion Intolerance by Transcranial Doppler Evaluation in Patients Undergoing Carotid Artery Stenting With Proximal Flow Arrest Protection System.
The aim of this observational pilot study is to determine whether intolerance of carotid occlusion during carotid artery stenting can be predicted with preprocedural transcranial Doppler evaluation.
- Trial name
- NCT01922609
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- University Hospital, Motol
Chronic Coronary Syndrome, Coronary Disease
SECURE Trial: Stress Echocardiography With Carotid Ultrasound vs Routine CT Coronary Angiography in Chronic Coronary Syndrome for Endpoints
Diseases of the heart and circulation are known as cardiovascular diseases, and they cause over 160,000 deaths each year. Coronary heart disease (CHD) is the most common cardiovascular disease.
- Conditions
- Chronic Coronary Syndrome, Coronary Disease, Coronary Artery Disease
- Trial name
- SECURE (NCT06185530)
- Testing
- Detection of obstructive coronary disease
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- London North West Healthcare NHS Trust
Carotid Stenosis
Role of the Type of Carotid Stent and Cerebral Protection on Cerebral Microembolization During Carotid Artery Stenting. A Randomized Study Comparing Carotid Wallstent vs Roadsaver® Stent and Distal vs Proximal Protection.
Stenting is an alternative to traditional surgery in the treatment of carotid stenosis.The intra and/or postprocedural cerebral embolization remains the most frequent complication.
- Trial name
- NCT02915328
- Testing
- Filterwire EZ™, MO.MA Ultra, Stent Roadsaver®
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Centro Cardiologico Monzino
Abdominal Aortic Aneurysm, Peripheral Artery Disease
A Study of Remote Ischaemic Preconditioning in Patients With Atherosclerosis Undergoing Vascular Surgery
The purpose of this study is to evaluate the effect of preoperative remote ischaemic preconditioning (RIPC) on organ damage and the functional characteristics of arteries in patients undergoing vascular surgery.
- Conditions
- Abdominal Aortic Aneurysm, Peripheral Artery Disease, Carotid Artery Stenosis
- Trial name
- NCT02689414
- Testing
- Remote ischaemic preconditioning, Control to RIPC
- Where
- Estonia
- Volunteers
- 98 people
- Sponsor
- Tartu University Hospital