Clinical trials: Case-Control Studies
Alzheimer Disease, Aging
Vanderbilt Memory and Aging Project
This study will use an observational cohort to cross-sectionally and longitudinally relate vascular health to clinical, imaging, and biological markers of early Alzheimer's disease and cerebrovascular disease among aging adults.
- Conditions
- Alzheimer Disease, Aging, Aged, 80 and Over, Biomarkers
- Trial name
- VMAP (NCT05372159)
- Testing
- none, observational study
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Vanderbilt University Medical Center
Orthodontic Appliance, Debonding
Comparison of Two Orthodontic Clean-Up Protocols
Orthodontic clean-up following debonding remains a technically demanding procedure, with documented risks of enamel roughening, microdefects, discoloration, and increased plaque retention.
- Conditions
- Orthodontic Appliance, Debonding, Case-control Study
- Trial name
- NCT07304310
- Testing
- Two-step ultrasonic protocol, One-step clean-up protocol
- Where
- Italy
- Volunteers
- 142 people
- Sponsor
- IRCCS San Raffaele
Henna, Hand-Foot Syndrome
Effectiveness of the Henna Application in Patients With Hand-Foot Syndrome: Nested Case-Control Study
Introduction: There is an explanation that there is a connection between the application of henna and the occurrence of hand-foot syndrome, and the purpose and progression of this interaction.
- Conditions
- Henna, Hand-Foot Syndrome, Case-Control Study
- Trial name
- [Henna] (NCT06832501)
- Testing
- Henna
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Hacettepe University
Keratoconus in One or Two Eyes for Case, Good Visual Acuity for Control
Influence of Keratoconus on Stress at Work
Keratoconus is a progressive disorder in which central and paracentral corneal stromal thinning occurs. No studies evaluated the influence of keratoconus on stress at work, nor the influence of treatments of keratoconus on stress…
- Trial name
- KERATOSTRESS (NCT04789707)
- Testing
- auto-questionnaire
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Parenting Education Curriculum, Parenting Education Curriculum + Case Management
Stepping Up 4 Your Child
Through Stepping Up 4 Your Child, non-custodial fathers will be provided with a comprehensive, solution-oriented program featuring group based parent education and individualized case management to help them achieve financial…
- Conditions
- Parenting Education Curriculum, Parenting Education Curriculum + Case Management, Waiting List Control
- Trial name
- 4yourchild (NCT02843113)
- Testing
- 4 Your Child Program
- Where
- 6 sites in United States
- Volunteers
- 1,266 people, healthy volunteers welcome
- Sponsor
- University of Louisville
HIV Risk Reduction, Attention Control Case Management
Disclosure to Family
The decision to disclose one's serostatus to family members creates considerable emotional strain for people living with HIV (PLWH), regardless of gender and sexual orientation.
- Trial name
- D2F (NCT02111720)
- Testing
- Maybe, Maybe Not, Comprehensive Risk Counseling and Services
- Where
- United States
- Volunteers
- 351 people
- Sponsor
- University of South Florida
Case Control Study
Vitamin D Deficiency Among Women With Unexplained Infertility
Does vitamin D is more deficient in women with unexplained infertility than in fertile pregnant women or not?
- Trial name
- Infertility (NCT03396237)
- Volunteers
- 108 people
- Sponsor
- Ain Shams Maternity Hospital
Case Control Study
Mammographic Density and the Risk of Tumor Recurrence in Asian Women: a Case-control Study
To evaluate the influence of mammographic breast density at diagnosis on the risk of cancer recurrence and survival outcome in patients with invasive breast cancer after surgery
- Trial name
- NCT02771665
- Testing
- Mammographic breast density at diagnosis
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Case-control Study
GENETIC SUSCEPTIBILITY FACTOR AS A PREDICTOR OF TYPE 2 DIABETES REMISSION AND WEIGHT LOSS AFTER BARIATRIC SURGERY
Obesity is directly related to an increased risk of diabetes mellitus, hypertension, dyslipidemia, cardiovascular disease, and overall mortality. Weight loss is effective in decreasing these risks and to reduce disease severity.
- Trial name
- OBEGEN (NCT02405949)
- Testing
- Genetic test
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Signet Ring Cell Carcinoma, Stomach Disease
Prognosis of Signet Ring Cells in Upper Digestive Neoplasms
Background • A major increase in incidence of signet ring cell adenocarcinomas (ADCI) of the upper digestive tract in western countries Discordant results in the literature concerning the prognosis value of the presence of signet…
- Conditions
- Signet Ring Cell Carcinoma, Stomach Disease, Oesophagus, Prognostic
- Trial name
- ADCI001 (NCT01249859)
- Where
- France
- Volunteers
- 2,500 people
- Sponsor
- University Hospital, Lille
1、Enough Cases, 2、Elekta Precise 1343 Digital Control Electron Linear Accelerator
Recombine Endostatin With Neoadjuvant Chemotherapy Followed by Concurrent Chemoradiation in Advanced Nasopharynx Cancer
1) Observe and compare the curative effect of endostatin/recombined Endostatin in alliance with neoadjuvant chemotherapy and Concurrent chemo-radio therapy to treat the local advanced nasopharyngeal darcinoma; 2) Evaluate the…
- Conditions
- 1、Enough Cases, 2、Elekta Precise 1343 Digital Control Electron Linear Accelerator, Can Undertake Nasopharyngeal Carcinoma Specimens in the Materia，, Image Department of Nose Pharynx Ministry MRI Dynamic Testing,
- Trial name
- NCT01689558
- Testing
- Recombine Endostatin
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jin Feng
The Investigators Collected 534 PCOS Patients as the Case Group,and 580 Infertile Women With Normal Ovulatory Cycle of the Control Group;, At the Same Time, the Investigators Continuedly Collect Cases to October 2012, and Totally Collected 579 Patients With PCOS Altogether;
The Potential Biochemical Diagnosis Criteria and Therapeutic Effect Indexes: Sex Hormone Binding Globulin Levels and Free Androgen Index in Blood of Patients With Polycystic Ovary Syndrome
To explore whether Free androgen index（FAI）can be regarded as biochemically diagnostic indexes of high androgen hormone in blood of patients with Polycentric ovary syndrome（PCOS）.
- Conditions
- The Investigators Collected 534 PCOS Patients as the Case Group,and 580 Infertile Women With Normal Ovulatory Cycle of the Control Group;, At the Same Time, the Investigators Continuedly Collect Cases to October 2012, and Totally Collected 579 Patients With PCOS Altogether;, 534 Patients in the Cases Group and 580 Women in the Control Group Received no Measures, While 579 Patients Received Drugs;, The Investigators Monitored Basic Indexes in Blood of All the Subjects in This Suvey,and Also Monitored Indexes of 579 Patients After Treatment.
- Trial name
- NCT01784380
- Testing
- Diane-35;metformin;Clomiphene citrate; Human menopausal gonadotropin
- Where
- 2 sites in China
- Volunteers
- 1,159 people
- Sponsor
- Zhongshan Bo Ai Hospital
Each Patient is Both Case and Control, 1 Embryo Will be Biopsied and 1 Embryo is Not
Evaluation of the Impact of Embryo Biopsy on the Reproductive Potential of Embryos Undergoing In Vitro Fertilization (IVF)
To assess the impact of embryo biopsy on the reproductive potential of human embryos.
- Trial name
- NCT01219504
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey