Clinical trials: Case-control Study
Sleep Bruxism, Masseter Muscle Hypertrophy
Changes in Electromyographic Activity in Aligner Treatment of Adult Patients With and Without Nocturnal Bruxism
The purpose of the study is to evaluate the effectiveness of clear aligners on the symptoms and signs reported by bruxism patients.
- Conditions
- Sleep Bruxism, Masseter Muscle Hypertrophy, Grinding Teeth
- Trial name
- EMG_BRUX (NCT06343194)
- Testing
- Bruxoff ®
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hepatocellular Carcinoma
Recurrence Risk Factors of Early-Stage Hepatocellular Carcinoma After Radio Frequency Ablation
The aim was to investigate the efficacy of radiofrequency ablation (RFA) with a multiple-electrode switching system (MESS) in the treatment of early hepatocellular carcinoma (HCC) and to evaluate the patterns and risk factors of…
- Trial name
- NCT02046356
- Testing
- MESS-RFA
- Where
- China
- Volunteers
- 139 people
- Sponsor
- Yunhua Tan
Liver Failure, Living Donor Liver Transplantation
Biliary Complication Rates in Living Donor Liver Transplantation: a Retrospective Comparative Study of Stent Versus Non-Stent Groups
Despite technological advancements in living donor liver transplantation (LDLT), biliary complications (BC), including biliary anastomotic stricture (BAS) and bile leak (BL), remain unresolved issues that significantly affect…
- Conditions
- Liver Failure, Living Donor Liver Transplantation, Biliary Complications, Biliary Stents
- Trial name
- NCT06767553
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Chungnam National University Hospital
Rheumatoid Arthritis
Study of Human Leukocyte Antigen (HLA) Polymorphisms in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA), affects between 0.3% and 1.0% of the population, it can lead to progressive joint destruction and severe disability.
- Trial name
- HLAPRPA (NCT01111357)
- Testing
- Collect of 10 ml of peripheric blood for DNA extraction
- Where
- Martinique
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
Healing Wound
Adjunctive Use of an Antibacterial Honey Dressing for Palatal Wound Healing After Harvesting a Free Gingival Graft
This case-control study will afford a more understanding of the clinically benefits that the antibacterial honey dressing material has in palatal wound healing and the subsequent effects in post-operative morbidity.
- Trial name
- NCT04269694
- Testing
- Medihoney dressing
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Colorectal Cancer; Gut Microbiota Dysbiosis
Intestinal Flora Differences Between Colorectal Cancer Patients and Healthy Individuals
This observational case-control study aims to compare the composition of intestinal microbiota between colorectal cancer (CRC) patients and healthy individuals.
- Trial name
- NCT06875648
- Testing
- Not applicable (observational study)
- Where
- China
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Hansung University
Bipolar Disorder (BD)
LRFN5 and OLFM4 in Bipolar Disorder
This cross-sectional observational case-control study evaluated serum levels of leucine-rich repeat and fibronectin type III domain-containing protein 5 (LRFN5) and olfactomedin-4 (OLFM4) in subjects with bipolar disorder (BD)…
- Trial name
- NCT07434414
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Elazığ Mental Health and Diseases Hospital
Kaposi's Sarcoma
Risk Factors for Non-HIV-Related Kaposi s Sarcoma
This study will try to identify risk factors for Kaposi s sarcoma, a rare skin cancer, and to understand the role of the KSHV virus in development of the disease.
- Trial name
- NCT00339326
- Where
- Italy
- Volunteers
- 1,383 people
- Sponsor
- National Cancer Institute (NCI)
Neuroendocrine Neoplasm of Lung, Neuroendocrine Neoplasm of Gastrointestinal Tract (Disorder)
Risk Factors for Neuroendocrine Neoplasms
Recent studies show an increase in neuroendocrine neoplasms, especially for the digestive tract. Previous studies suggest various risk factors that were observed for various tumor sites, e.g.
- Trial name
- NCT06282016
- Testing
- Case-control study (no intervention)
- Where
- Germany
- Volunteers
- 14,250 people, healthy volunteers welcome
- Sponsor
- Bavarian Cancer Registry
COVID-19
Cardiovascular Risk Factors and Severe COVID-19. A Nationwide Registry-based Case-Control Study
In this study we cross-reference several nationwide high-quality Swedish registers in order to study risk factors for severe Covid-19 outcomes.
- Trial name
- NCT04426084
- Testing
- Hypertension, Diabetes type 2, Obesity
- Where
- Sweden
- Volunteers
- 22,784 people
- Sponsor
- Karolinska Institutet
Arthritis, Rheumatoid, Stress Disorder
Impact of Life Events and Psychological Stress in Rheumatoid Arthritis Set-up : Case-control Study Within a Multifactorial and Integrative Psychological Model
Rheumatoid Arthritis (RA) is an inflammatory rheumatic disease that can lead to structural damage and handicap. The RA physiopathology is multifactorial, including genetic and environmental risk factors.
- Trial name
- Stress-PR (NCT03550833)
- Testing
- Questionnaire, blood sample
- Where
- 5 sites in France
- Volunteers
- 152 people
- Sponsor
- University Hospital, Bordeaux
MEDICATION RELATED OSTEONECROSIS OF THE JAW
OZONE_EXO: Comparative Analysis of Protocols for Dental Exactions in Patients at Risk of MRONJ: Case-control Study
Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse reaction of antiresorptive and antiangiogenic agents; it is also a potentially painful and debilitating condition.
- Trial name
- OZONE_EXO (NCT06072404)
- Testing
- OxigenOzone_Insufflation
- Where
- Italy
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Bipolar Disorder I
Melatonin and Response to Lithium
Bipolar disorders are mental illnesses characterized by the recurrence of mood-episodes, that can have a severe impact on the life of individuals.
- Trial name
- MeLiR (NCT05878730)
- Testing
- urine collection, Level of Proteins, Level of mRNA and miRNA
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post COVID-19 Condition
Periodontal Health in Post COVID-19 Patients
The aim of this study is; To Assess the association between periodontal health and Matrix metalloproteinase-8 (MMP-8) level in Gingival Crevicular Fluid (GCF) in post COVID-19 patients.
- Trial name
- NCT05950230
- Testing
- Assess Periodontal Health Status, Collecte GCF samples by paperstrip
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Orthopedic Disorder
Routine Preoperative Evaluation in Surgical Patient
The "routine" pre-operative tests in healthy orthopaedic patients undergoing intermediate/ major surgery are not justified. In this study of 670 healthy orthopedic patients with 7610 preoperative tests, investigators found that…
- Trial name
- NCT04196166
- Testing
- preoperative blood tests
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Postpartum Acute Urinary Retention
Determination of Risk Factors of Postpartum Urinary Retention
Postpartum urinary retention is an uncommon complication of the vaginal delivery. Failure to diagnose it may have a real impact both on the urinary plane but also on the psychological level.
- Trial name
- PAUR (NCT03876756)
- Testing
- postpartum acute urinary retention, no postpartum acute urinary retention
- Where
- France
- Volunteers
- 192 people
- Sponsor
- Hospices Civils de Lyon
Case Control Study
Vitamin D Deficiency Among Women With Unexplained Infertility
Does vitamin D is more deficient in women with unexplained infertility than in fertile pregnant women or not?
- Trial name
- Infertility (NCT03396237)
- Volunteers
- 108 people
- Sponsor
- Ain Shams Maternity Hospital
Tooth Loss, Disorder Related to Renal Transplantation
Osseointegrated Dental Implants in Kidney Transplanted Patients
The evaluation of the bone, using several techniques and on several aspects will be the purpose to study the possible impact of the kidney transplant (and, extensively, the pre-transplant dialysis, the organ replacement and the…
- Trial name
- NCT02513602
- Testing
- Dental implant insertion
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- University of Trieste
Polymorphism (Genetics), Endometriosis
Influence of WNT4 VEZT FSHB and SIRT1 SNPs in Endometriosis: a Case Control Study of the Sardinian Population
Endometriosis, defined as the presence of endometrial tissue outside the uterine cavity, affects 6-10% of the general population of women in childbearing age. The pathogenesis of the disease is unknown.
- Trial name
- NCT02388854
- Testing
- SNPs analysis with Sanger sequencing
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Coronary Artery Disease
A Case-control Study to Assess the Association Between Facial Characteristics and Coronary Artery Diseases
The purpose of this study is to explore the facial characteristics associated with the increased risk of coronary artery diseases.
- Trial name
- NCT03214783
- Testing
- Facial characteristics
- Where
- China
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- China National Center for Cardiovascular Diseases
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