Clinical trials: Case-control Study
Dystonia
The Dystonia Coalition Natural History and Biospecimen Repository for Isolated Dystonias
Dystonia is a disorder characterized by excessive involuntary contraction of muscles with repetitive and patterned movements. The isolated dystonias are the most common type of dystonia and include Limb dystonias (like writer's…
- Trial name
- DCP (NCT01373424)
- Where
- 42 sites in United States, Australia and 5 more
- Volunteers
- 3,265 people
- Sponsor
- Emory University
Chronic Obstructive Pulmonary Disease, Osteoporosis
Case Control Study: Determinants of Osteoporosis in GOLD II COPD Patients.
Patients with COPD have been found to have an increased risk of osteoporosis. The underlying mechanism is not clear yet. This case control study aims to identify risk factors for osteoporosis in GOLD II COPD patients.
- Trial name
- NCT00725673
- Where
- Netherlands
- Volunteers
- 106 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Periodontitis, Diabetes
Nonsurgical Periodontal Care for Diabetes Patients: A Case-Control Study
Diabetes mellitus (DM) and periodontitis are two chronic diseases that are interconnected. The coexistence of these conditions leads to increased severity of periodontitis and challenges in controlling blood glucose levels in…
- Trial name
- NCT06506370
- Testing
- nonsurgical periodontal treatment
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad de Murcia
Crohn's Disease, Intestinal Fibrosis
68Ga-FAPI-46 PET/CT for Assessing Small Bowel Fibrostenosis in Crohn's Disease
This study is a prospective, case-control study evaluating whether the PET radiotracer 68Ga-FAPI-46 can detect fibrostenosing Crohn's disease in the small bowel.
- Conditions
- Crohn's Disease, Intestinal Fibrosis, Inflamatory Bowel Disease, Intestinal Strictures Related to Crohn´s Disease
- Trial name
- FAPI-PETCD (NCT07273188)
- Testing
- Ga68-FAPI-46
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Mayo Clinic
Acetaminophen, Drug-Induced Liver Injury
Screening of Susceptibility Genes for APAP Induced Drug Induced LIver Injury in ChiNese Population: a Case-control Study
Acetaminophen (APAP) is the most commonly used NSAIDS in clinic, and it is also a common cause of drug-induced liver injury (DILI).
- Conditions
- Acetaminophen, Drug-Induced Liver Injury, Pharmacogenetics, China
- Trial name
- PAIN (NCT04964310)
- Testing
- genetic polymorphism
- Where
- China
- Volunteers
- 339 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Arthritic Psoriasis, Psoriasis (PsO)
Retinal Capillary Vessel Density and Foveal Avascular Zone Size in Patients With Psoriatic Arthritis: A Case-Control Study.
In terms of blood flow per unit of tissue, the retina is one of the tissues with the highest blood flow in the body. Parameters such as the thickness of the choroid layer, which plays a crucial role in maintaining normal eye…
- Conditions
- Arthritic Psoriasis, Psoriasis (PsO), Retinal Vessels
- Trial name
- PsA-RETINA (NCT07858591)
- Testing
- OCTA-SCP, OCTA-DCP, OCTA-RPC
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Primary Open-angle Glaucoma, Glaucoma
Assessment of Endothelial Glycocalyx in Patients With Primary Open-angle Glaucoma
The glycocalyx is a fibrillary lining structure that covers the inner surface of blood vessels. Composed of glycoproteins and polysaccharides, it is an essential determinant of vascular endothelial physiology: it limits…
- Trial name
- GLAUCALYX (NCT05264818)
- Testing
- Glycocheck, Ophthalmological examinations
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
COVID-19
Cardiovascular Risk Factors and Severe COVID-19. A Nationwide Registry-based Case-Control Study
In this study we cross-reference several nationwide high-quality Swedish registers in order to study risk factors for severe Covid-19 outcomes.
- Trial name
- NCT04426084
- Testing
- Hypertension, Diabetes type 2, Obesity
- Where
- Sweden
- Volunteers
- 22,784 people
- Sponsor
- Karolinska Institutet
Influenza
Effectiveness of Flu Vaccination and Burden of Illness Among Community-dwelling Elderly With Influenza Like Illness in Brazil
The purpose of this research study is to estimate how many elderly people who have symptoms that look like influenza (i.e. an influenza-like illness) actually have the disease and how effective influenza vaccines are in…
- Trial name
- NCT01171157
- Testing
- Routine sample collection
- Where
- Brazil
- Volunteers
- 4 people
- Sponsor
- GlaxoSmithKline
Onchocercal Subcutaneous Nodule, Epilepsy
Onchocerciasis-Associated Epilepsy, an Explorative Case-control Study
This is an exploratory case control study with the aim to compare the Onchocerca volvulus virome between persons with onchocerciasis-associated epilepsy (OAE) and persons with onchocerciasis but without epilepsy.
- Conditions
- Onchocercal Subcutaneous Nodule, Epilepsy, Virus
- Trial name
- NCT05868551
- Testing
- nodulectomy
- Where
- South Sudan
- Volunteers
- 40 people
- Sponsor
- Universiteit Antwerpen
Anorexia Nervosa
Impairment of Central Coherence in Restrictive Anorexia Nervosa (CoCA)
The current etiological pathological model of anorexia nervosa is poly-factorial involving individual genetic and psychological factors, in close interaction with environmental, family and socio-cultural factors.
- Trial name
- CoCA (NCT02381639)
- Testing
- One interview of 90 minutes with a part of cognitive assessment and a part of self-assessment
- Where
- France
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Viral Infection
Analysis of Human to Human Transmission of Middle East Respiratory Syndrom Coronavirus (MER-CoV)
This study aimed to analysis the characteristics of MERS transmission and the effect of our institutional personal protective equipment on the controlling the MERS at a tertiary Korean Hospital.
- Trial name
- MKU (NCT02605109)
- Testing
- Risk of MERS infection
- Volunteers
- 200 people
- Sponsor
- Konkuk University Medical Center
Fiberoptic Bronchoscopy (FOB), Lung Cancer (Diagnosis)
Nebulized Lidocaine And Ketamine Before Fiberoptic Bronchoscopy
The current study is looked for the comparison between nebulized lidocaine and ketamine, nebulized lidocaine, and usual lidocaine spray in the oral and nasal cavities before flexible bronchoscopy.
- Conditions
- Fiberoptic Bronchoscopy (FOB), Lung Cancer (Diagnosis), Premedication
- Trial name
- NCT07743333
- Testing
- Nebulized lidocaine and ketamine, Nebulized Lidocaine, Lidocaine spray (2%)
- Where
- Egypt
- Volunteers
- 134 people
- Sponsor
- Alexandria University
Heart Arrest, Out-Of-Hospital, Hypoxia-Ischemia, Brain
Neuropsychological Outcome After Cardiac Arrest
This study is a sub-study to the large pragmatic Target Temperature Management 2 Trial (TTM2-trial, ClinicalTrials.gov Identifier: NCT02908308), assessing effectiveness of controlled hypothermia after out-of-hospital cardiac…
- Conditions
- Heart Arrest, Out-Of-Hospital, Hypoxia-Ischemia, Brain, Cognition Disorders, Psychological Distress
- Trial name
- NCT03543371
- Testing
- Neuropsychological assessment
- Where
- 8 sites in Denmark, Sweden and 1 more
- Volunteers
- 200 people
- Sponsor
- Region Skane
Periodontitis, Alzheimer Disease
Oral Bacterial and Viral Mapping by Dental Plaque in Elderly Patients With and Without Alzheimer's Disease(ORal MICrobiology in Alzheimer's Patients)
The neurological disorders that accompany aging represent a major public health problem. The management of these diseases is a major medical and social priority.
- Trial name
- ORAMICAL (NCT04869904)
- Testing
- dental and plaque sampling
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Pharyngitis
Loco-regional Complications of Pharyngitis in Children: a National Case-Control Study
To study the association between several exposures of interest and the occurrence of infectious loco-regional complications of pharyngitis in children.
- Trial name
- CAPE (NCT03237299)
- Testing
- Collection of data, No collection of data
- Where
- France
- Volunteers
- 289 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Periodontal Diseases
Serum Levels of Vitamin D and IL8 in Patients With Periodontitis
We evaluated vitamin D and IL8 levels in the serum of patients with periodontitis as well as the healthy controls to correlate their levels with the degree of periodontitis.
- Trial name
- NCT06306937
- Testing
- Evalution of serum levels of vitamin D and IL8
- Where
- Egypt
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Endothelial Function and Arterial Stiffness
A Pilot Case Control Study of Vascular Function in Cyclists
This is a pilot study with the purpose of measuring vascular function, assessed by evaluating arterial stiffness (pulse wave velocity and augmentation index) and endothelial function (flow mediated dilatation), in elite/amateur…
- Trial name
- NCT02745665
- Testing
- flow mediated dilation (endothelial function), ABPI, Pulse wave velocity and augmentation index
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
Pre-Eclampsia
Prospective Case-Control Study of Cardiovascular Changes in Pregnancy Related Hypertensive Disorders
This is a research study to understand the changes in the heart and the cardiovascular system that may occur in women who develop high blood pressure during pregnancy.
- Trial name
- ARTSEN (NCT04713228)
- Testing
- ARTSENS Pen
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Adhesive Capsulitis
Assessment of Shoulder Peak Torque and Fatigue Index in Individuals With Adhesive Capsulitis
Adhesive capsulitis (AC) is a common painful disorder associated with diminishing glenohumeral movement. This has led to the need for an evidence-based approach to assess the isokinetic strength and endurance of shoulder muscles…
- Trial name
- AC (NCT07520604)
- Testing
- shoulder abductor, internal rotator and external rotator Isokinetic peak torques and fatigue indices
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
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