Clinical trials: Case-control Study
Osteoporosis
Bisphosphonates Effects On Alveolar Bone Among Osteoporotic Women
Osteoporosis is a public health problem. It is a skeletal disease being treated by Bisphosphonates as the first choice medication.
- Trial name
- NCT02115490
- Testing
- Bisphosphonates
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University
Colorectal Cancer, Early Onset Colorectal Cancer
Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer
An increase in early-onset colorectal cancers (eoCRC), defined as a CRC before 50 years, is confirmed globally. CRC pathogenesis has been associated with several risk factors (family history, germline pathogenic variants…
- Conditions
- Colorectal Cancer, Early Onset Colorectal Cancer, Diet Habit, Risk Reduction
- Trial name
- DEMETRA (NCT05732623)
- Testing
- Semi Quantitative Food Frequency Questionnaire (SQFFQ)
- Where
- 8 sites in United States, Finland and 4 more
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- San Raffaele University
Gastric Cancer
The Effect of Prucalopride Succinate on Gastrointestinal Motility After Laparoscopic Gastrectomy : Prospective Double Blind Case-control Study
In order to improve postoperative ileus in patients undergoing gastrointestinal surgery, digestive medications and prokinetics have been routinely used.
- Trial name
- NCT05966246
- Testing
- Arm I : Experimental (Prucalopride succinate group), Arm II : Control (Mosapride citrate group)
- Where
- South Korea
- Volunteers
- 106 people
- Sponsor
- Gangnam Severance Hospital
Motor Activity
The Animal Fun Program to Support the Motor Development of the Italian Pre-schoolers: a Case-Control Study
The present literature supports the importance of the motor activity since the early stages of the human development. The children with poor motor skills are at greater risk for psychosocial, internalizing, and metabolic…
- Trial name
- NCT04714580
- Testing
- Animal Fun Program
- Where
- Italy
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Epidemiology
Epidemiology of Malaria in Ubon Ratchathani, Thailand
This is an observational study (case-control study) aiming to identify risk factors for malaria infection in health centers or malaria posts or district hospitals in Buntharik District and Nachalui District, Ubon Ratchathani…
- Trial name
- NCT02991963
- Testing
- Interview, Blood collection (Dried Blood Spot), Blood Collection (Venous Blood collection)
- Where
- Thailand
- Volunteers
- 660 people
- Sponsor
- University of Oxford
Acetabular Labrum Tear, Ultrasound Exams
A Prospective Case-control Clinical Study of the Ultrasound Imaging Reporting and Data System for Diagnosis of Anterosuperior Acetabular Labral Tears
The goal of this clinical trial is to develop an ultrasonic imaging reporting and data system for diagnosis of anterosuperior acetabular labral tears (ALT).
- Conditions
- Acetabular Labrum Tear, Ultrasound Exams, Diagnostic Imaging, Models
- Trial name
- NCT06744192
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Yi Mao
Barrett Esophagus, Esophageal Adenocarcinoma
Efficacy of EsoGuard Assay on Esophageal Surface Cells Collected With EsoCheck vs EGD for the Diagnosis of BE or EAC
The study will assess the performance of the combined system, i.e., the use of the EsoGuard assay (lab developed test) on cells collected using the EsoCheck (501k cleared device) to detect Barrett's Esophagus (BE), with or…
- Conditions
- Barrett Esophagus, Esophageal Adenocarcinoma, Barretts Esophagus With Dysplasia, Barrett's Esophagus Without Dysplasia
- Trial name
- ESOGUARDBE2 (NCT04295811)
- Testing
- EsoGuard (lab assay), Esophagogastroduodenoscopy
- Where
- 35 sites in United States, Netherlands
- Volunteers
- 784 people, healthy volunteers welcome
- Sponsor
- Lucid Diagnostics, Inc.
Acute Kidney Injury, Septic Shock
RRT With a Cytokine Absorption Filter (oXiris ®) in Patients With Septic Shock
Acute kidney injury (AKI) is a common complication in critically ill patients. Multiple studies have reported evidence that the main cause of ARF is sepsis, as part of the Multiple Organ Dysfunction Syndrome: up to 50% of septic…
- Trial name
- NCT04952714
- Testing
- Oxiris
- Where
- Colombia
- Volunteers
- 93 people
- Sponsor
- Clinica CES
Carcinoma, Hepatocellular, Cirrhosis, Liver
Case-Control Study of the Glycotest™ HCC Panel vs AFP for the Detection of Early-stage Hepatocellular Carcinoma
Clinical guidelines (AASLD) recommend the use of abdominal ultrasound (US) for surveillance testing for the early detection of Hepatocellular Carcinoma (HCC).
- Trial name
- NCT03878550
- Where
- 20 sites in United States, Israel
- Volunteers
- 766 people
- Sponsor
- Glycotest, Inc.
Neonatal Encephalopathy
Uterine Activity in Moderate-Severe Neonatal Encephalopathy: A Case Control Study
Excessive uterine activity may be one of several aetiological factors that contribute to depressed neurological function in the newborn.
- Trial name
- NCT03122808
- Testing
- Uterine Activity Analysis, Partogram Analysis
- Where
- Ireland
- Volunteers
- 264 people
- Sponsor
- The Rotunda Hospital
Chronic Subdural Hematoma
Association Between Dietary Factors and Chronic Subdural Hematoma (DISH)
A prospective, multicenter, case control trial is designed to compare difference in dietary and nutritional factors in patients with and without chronic subdural hematoma.
- Trial name
- DISH (NCT05599217)
- Testing
- Dietary and nutritional questionnaire, Neurological function, cognitive function, and life quality assessment, Peripheral blood test
- Where
- 4 sites in China
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Nursing Education
Effects of Case-Based Learning in Nursing Ethics Education
This randomized controlled study evaluated the effect of case-based learning on nursing students' ethical values and perceptions of caring behaviors.
- Trial name
- NCT07845279
- Testing
- Case-Based Learning, Standard Ethics Education
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Bilecik Seyh Edebali Universitesi
Rotavirus Gastroenteritis
Rotavirus Gastroenteritis and Vaccine Usage in Rhode Island
The goals of this study are to see what effects the introduction of RV5(RotaTeq) vaccine has had in the community both on the number of rotavirus-associated hospitalizations and on the strains of rotavirus circulating in the…
- Trial name
- NCT01026779
- Where
- United States
- Volunteers
- 803 people
- Sponsor
- Lifespan
First Recently-diagnosed Colorectal Cancer
AGARIC Case Control Study
The aim of the study is to establish the existence of a relationship between the dietary intake of polyunsaturated fatty acids (PUFA) and the risk of colorectal cancer in humans, using 2 reliable and complementary biomarkers: the…
- Trial name
- AGARIC (NCT01966081)
- Testing
- Blood sample, tissue samples from abdominal subcutaneous adipose
- Where
- 5 sites in France
- Volunteers
- 551 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Chronic Rhinosinusitis Without Nasal Polyps, Chronic Rhinosinusitis (Diagnosis)
Pistacia Lentiscus Oil Nasal Drops for Preventing Recurrence of Chronic Rhinosinusitis
This retrospective, observational, case-control clinical study evaluated the safety and efficacy of nasal drops containing Pistacia lentiscus oil in preventing recurrence of chronic rhinosinusitis during long-term therapy.
- Trial name
- NCT07198607
- Testing
- Pistacia lentiscus Oil Nasal Drops (Bactorinol®), Isotonic Saline Nasal Wash
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Oral Potentially Malignant Lesions
Cathelicidin LL-37 Relation to Potentially Malignant Lesions
LL-37 appears to have a potential role in potentially malignant lesions (OLP \& leukoplakia). The remarkable diagnostic accuracy of salivary LL-37 in differentiating potentially malignant lesion and healthy control could confirm…
- Trial name
- NCT06219330
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Craniosynostoses, Pain, Postoperative
Scalp Block Decreases Pain and Side Effects
Postoperative analgesia after corrective surgery of paediatric craniosynostosis is crucial in term of short and long-term outcomes.
- Trial name
- NCT04133467
- Testing
- scalp block
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Type1diabetes
The Relationship of RAGE Gene Polymorphism With Type I Diabetes in Egyptian Patients
Type I Diabetes Mellitus (TIDM) is a chronic metabolic disorder caused by the immune-mediated T-cell and macrophages that typically affects insulin-producing β-cells of Langerhans leading to cell destruction and absolute insulin…
- Trial name
- NCT05874323
- Testing
- Detection of RAGE gene polymorphism (rs1800625)
- Where
- Egypt
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Hyperemesis Gravidarum, Pregnant With Complication
Pepsinogen-1 Serum Levels in Hyperemesis Gravidarum
In this study, the investigators planned to investigate maternal serum pepsinogen-1 (MSPG-1) levels in pregnant women with severe hyperemesis gravidarum (HG) and pregnant women without severe HG.
- Trial name
- NCT06581796
- Testing
- pepsinogen-1
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Lung Fibrosis
Impact of Airway Mucus Plugs on Secondary Pulmonary Fibrosis in COPD Patients: A Single-Center Case-Control Study
Chronic obstructive pulmonary disease (COPD) is frequently accompanied by airway mucus plugs, which are closely associated with airflow obstruction, acute exacerbations, and increased mortality.
- Trial name
- NCT07236541
- Testing
- No intervention; observational biospecimen collection only
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Ming Zhong
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.