Clinical trials: Case-control Study
Obesity, Obesity, Childhood
Associations Between Obesity, Dental Caries, Erosive Tooth Wear and Periodontal Disease in Adolescents: A Case Control-study
Objectives To compare oral health (dental caries, periodontal status, and erosive tooth wear (ETW)), diet and oral hygiene habits between obese and normal weight adolescents, and to explore possible risk associations.
- Conditions
- Obesity, Obesity, Childhood, Tooth Wear, Tooth Erosion
- Trial name
- NCT05146557
- Testing
- Dental examination
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University Ghent
Type1diabetes, Sleep
Sleep Patterns and Chronotype in Children With and Without Type 1 Diabetes
Type 1 diabetes (T1D) is one of the most common chronic childhood diseases. Recent studies have highlighted the strong association between type 1 diabetes and sleep health problems.
- Conditions
- Type1diabetes, Sleep, Chronotype
- Trial name
- NCT06318611
- Testing
- sleep, chronotype
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Koç University
Parkinson Disease
The Parkinson's Disease Case-Control Study
The Parkinson's Disease Case-Control Study is a study of healthy volunteers and patients with Parkinson's disease aged 50-75 years living in Hangzhou, China.
- Trial name
- NCT06848192
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Westlake University
Placenta Accreta Spectrum, Placenta Accreta / Percreta
Relaxin and Placental Volume in Placenta Accreta Spectrum
This retrospective case-control study investigated the potential role of circulating relaxin levels and estimated placental volumes (EPV) in the pathogenesis and diagnosis of placenta accreta spectrum (PAS) disorders.
- Trial name
- NCT06808165
- Testing
- relaxin
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
COPD
Impact of Pulmonary Rehabilitation on Direct Healthcare Costs in Chronic Obstructive Pulmonary Disease (COPD)
The purpose of this study is to study the direct cost of illness study of COPD patients who participated in a Pulmonary rehabilitation program for 8 weeks.
- Trial name
- NCT01545128
- Volunteers
- 70 people
- Sponsor
- East and North Hertfordshire NHS Trust
Anesthesia; Adverse Effect, Cesarean Section Complications
Factors Associated With Failed Spinal Anesthesia for Cesarean Delivery
The aim of this study is to reveal the factor associated with failed spinal anaesthesia in cesarean delivery. We conduct the retrospective case-control study to elucidate the involving factors.
- Trial name
- NCT04685980
- Testing
- spinal anaesthesia with local anaesthetic and intrathecal morphine
- Where
- Thailand
- Volunteers
- 440 people
- Sponsor
- Mahidol University
Periodontitis
Association Between Periodontitis and Coronavirus Disease (COVID-19)
The study is a case control study investigating the association between Periodontitis and Coronavirus disease (COVID-19) in Egyptian dental patients attending the oral diagnosis clinic at faculty of Dentistry, Cairo University.
- Trial name
- NCT05278468
- Testing
- PCR test for covid-19
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Cataract, Glaucoma
Oculusgen (Ologen) Collagen Matrix Implant for Phaco-Trabeculectomy in Primary Glaucoma: A Case-Control Study
The objective of this study is to determine the safety and effectiveness of the OculusGen™ (ologen) Biodegradable Collagen Matrix Implant in hacotrabeculectomy surgery.
- Trial name
- NCT00687791
- Testing
- ologen™ Collagen Matrix Implant as an aid in phacotrabeculectomy surgery
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Pro Top & Mediking Company Limited
Ebola Virus Disease
REVIVE (Response to the Ebola Virus Vaccine)
This study is a vaccine-related clinical trial which will be conducted by our study team at Kenema Government Hospital (KGH)'s Viral Hemorrhagic Fever Program in collaboration with Tulane University School of Medicine.
- Trial name
- NCT05992480
- Testing
- rVSVDG-ZEBOV-GP Ebola Virus Vaccine (ERVEBO)
- Where
- Sierra Leone
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tulane University
Transfusion-Related Acute Lung Injury, ARDS, Human
Comparison of the Proteome in ICU Patients in Search for TRALI Biomarkers: A Case-control Study Using Both Retrospective and Prospective Samples
Transfusion-related acute lung injury (TRALI) is a severe complication of blood transfusions. After a transfusion, TRALI develops in 0.08-15% of cases depending on the characteristics of the studied population.
- Trial name
- CURIE (NCT06444750)
- Testing
- Blood sample collection
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Tuberculosis
Effect of Community Active Case Finding Strategies for Detection of Tuberculosis in Cambodia
Tuberculosis (TB) is a highly stigmatized disease, and approximately one-third of the Cambodian population living with TB are undetected.
- Trial name
- NCT04094350
- Testing
- ACF with a seed-and-recruit model, ACF targeting household and neighborhood contacts, ACF targeting the older population using mobile screening units
- Where
- 3 sites in Cambodia
- Volunteers
- 2,004 people
- Sponsor
- National University of Singapore
Chronic Intestinal Pseudo-Obstruction
Pseudo-obstruction Assessment With MRI
This study will explore the potential for a standardized MRI scan after a liquid meal to be used in diagnosis of the rare but debilitating chronic intestinal pseudo-obstruction (CIPO).
- Trial name
- POM (NCT04193735)
- Testing
- MRI scans after a liquid meal
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of Nottingham
Labor Pain, Pregnancy
The Association Between Decreasing Labor Analgesia Epidural Infusion and Forceps Delivery
The objective of this study will be to compare epidural infusion management, specifically looking at infusion rate changes, in patients who receive forceps deliveries versus normal spontaneous vaginal deliveries.
- Trial name
- NCT00443560
- Testing
- Case controlled analysis of epidural labor analgesia patterns
- Where
- United States
- Volunteers
- 2,162 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Graves Disease
Prevalence of Circulating Parvovirus Genome in Recently Diagnosed Graves' Disease: a Case-control Study
Lymphocytic thyroiditis is the most common autoimmune disease, usually affecting young women. Although the aetiology and pathogenesis remain obscure, the most widely accepted hypothesis is an interaction between a genetic…
- Trial name
- GPCBasedow (NCT02798965)
- Testing
- serodiagnosis
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Lipedema
Evaluation of Physical Activity in Women With Lipedema
This study will be conducted with women diagnosed with lipedema who were referred to the Lymphedema Rehabilitation Unit of the Physiotherapy and Rehabilitation Department at Gazi University Faculty of Health Sciences for…
- Trial name
- NCT07458932
- Where
- Turkey (Türkiye)
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Gazi University
Endometrial Cancer
Study of Insulin Resistance and Endometrial Cancer in Harris County, Texas
The goal of this clinical research study is to find out if there is a link between insulin resistance (or pre-diabetes) and endometrial cancer. Primary Objective: 1.
- Trial name
- NCT00495235
- Testing
- Questionnaire
- Where
- 8 sites in United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
HIV Infection
HLA-B*5701 And Hypersensitivity To Abacavir
This retrospective case-control study is being conducted to estimate the sensitivity of the pharmacogenetic marker, HLA-B*5701 for hypersensitivity to abacavir (ABC HSR).
- Trial name
- NCT00373945
- Testing
- Observational Study
- Where
- 55 sites in United States
- Volunteers
- 280 people
- Sponsor
- GlaxoSmithKline
Marfan Syndrome
Clinical Signs and Activity Limitations Associated With Dural Ectasia in Patients With Marfan Disease
Primary outcome is to compare the frequency and clinical features of spinal symptoms between Marfan patients with dural ectasia (cases) and those without (controls). 1. / Frequency of orthostatic headaches 2.
- Trial name
- MARFANLOMB (NCT05123339)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Venous Thromboembolism, Deep Vein Thrombosis (DVT)
Effectiveness and Cost-effectiveness of VTE Prevention Strategies in Gynecological Surgery
Venous thromboembolism (VTE) is a highly preventable but potentially fatal complication following gynecological surgery. The Caprini risk assessment model is widely used, but real-world evidence evaluating the net clinical…
- Conditions
- Venous Thromboembolism, Deep Vein Thrombosis (DVT), Pulmonary Embolism (PE), Gynecological Surgery
- Trial name
- NCT07455253
- Where
- China
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Nantong University
Pancreas Neoplasm, Pancreatitis
EUS Shear Wave for Solid Pancreatic Lesions.
The diagnosis of pancreas diseases is based on a combination of clinical signs, symptoms, and laboratory tests, but mainly on imaging techniques such as computed tomography (CT) and magnetic resonance (MR).
- Conditions
- Pancreas Neoplasm, Pancreatitis, Pancreatitis, Acute, Pancreatitis, Chronic
- Trial name
- NCT05095831
- Testing
- Pancreas EUS shear wave, Pancreas EUS-elastography and EUS-guided biopsy
- Where
- Ecuador
- Volunteers
- 25 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
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