Clinical trials: Case-control Study
Idiopathic Adolescent Scoliosis
Altered Hemorology in Adolescent Idıopathic Scoliosis
This study aims to investigate potential alterations in hemorheological parameters in adolescents with idiopathic scoliosis (AIS) compared to healthy controls.
- Trial name
- AHIAIS (NCT07102862)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Ventilation Mode, Pleth Variability Index
Effects of Volume and Pressure-Controlled Ventilation on Cerebral SpO2, PI, and PVI Index in Septoplasty
Objective: This study was designed to evaluate the accuracy of Pleth Variability Index (PVI), Perfusion Index (PI) and Regional Oxygen Saturation (rSO2) in both ventilation modes in patients undergoing septorhinoplasty operation…
- Conditions
- Ventilation Mode, Pleth Variability Index, Perfusion Index, Regional Cerebral Oxygen Saturation
- Trial name
- NCT06407362
- Testing
- Cerebral Oxygen Saturation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Peanut Allergies in Children
Pilot Study to Evaluate the Effect of Ketotifen on the Adverse Events Associated With Peanut Desensitization
The primary objective of this study is to evaluate, compared to non-treatment, the impact of a titrated dose (1 mg once a day, then 1 mg twice a day and finally a full 2 mg twice a day) of ketotifen on the adverse event profile…
- Trial name
- NCT01625715
- Testing
- Ketotifen
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Gordon Sussman Clinical Research
Varicocele
Lactoferrin and Iron in Seminal Plasma of Varicocele
Infertility is defined by World Health Organization (WHO) as a disease of reproductive system characterized by failure to achieve clinical pregnancy even after 12 months or more of regular unprotected sexual intercourse.
- Trial name
- NCT05171504
- Volunteers
- 75 people
- Sponsor
- Assiut University
Non Small Cell Lung Cancer
Radiotherapy Combined With Immunotherapy for Brain Metastases of Non-small Cell Lung Cancer
This is a Retrospective, Multicenter, Controlled Study to Evaluate Immunotherapy and Radiotherpay for Brain Lesions as a Potential Treatment for Patients with Brain Metastasis in non-small cell lung cancer
- Trial name
- NCT04835025
- Testing
- PD-1/PD-L1 inhibitor
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
Neonatal Encephalopathy
Uterine Activity in Moderate-Severe Neonatal Encephalopathy: A Case Control Study
Excessive uterine activity may be one of several aetiological factors that contribute to depressed neurological function in the newborn.
- Trial name
- NCT03122808
- Testing
- Uterine Activity Analysis, Partogram Analysis
- Where
- Ireland
- Volunteers
- 264 people
- Sponsor
- The Rotunda Hospital
Covid19, Pulmonary Embolism
Does COVID-19 Infection Increase the Risk of Pulmonary Embolism?
The World Health Organization (WHO) declared the 2019 novel coronavirus (COVID-19) a pandemic on March 11, 2020. As of 19 July 2020, there have been 14.3 million confirmed cases and over 600,000 confirmed deaths.
- Trial name
- NCT04696913
- Testing
- Exposure: Positive COVID-19 infection, Exposure: Negative COVID-19 infection
- Where
- United Kingdom
- Volunteers
- 347 people
- Sponsor
- University of Aberdeen
Age- Related Macular Degeneration, Diabetic Retinopathy
A Case-Control Study Revealing Intraocular Microenvironment Characteristics in Patients With Ocular Diseases Based on Multi-Omics Analysis
This project systematically investigates the role of the intraocular microbiome in various ocular diseases, including age-related macular degeneration, diabetic retinopathy, and cataracts.
- Conditions
- Age- Related Macular Degeneration, Diabetic Retinopathy, Retinal Vein Occlusion, Central Serous Chorioretinopathy
- Trial name
- NCT07897513
- Testing
- Not applicable- observational study
- Volunteers
- 150 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Leukemia
Case-Control Study of Pesticides and Childhood Leukemia
Childhood leukemia is the most common type of childhood cancer and its etiology is largely unknown. Most case-control studies of childhood leukemia have reported elevated risks among children whose parents were occupationally…
- Trial name
- NCT00342888
- Where
- United States
- Volunteers
- 629 people
- Sponsor
- National Cancer Institute (NCI)
Urinary Stone
2D:4D Digit Ratio and Urinary Stone Disease
This prospective observational case-control study will investigate whether the 2D:4D digit ratio is associated with urinary stone disease.
- Trial name
- NCT07736924
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Emrah Kızılay
Diminished Ovarian Reserve
Characterization of Gut and Tongue Coating Microbiota in Patients With Diminished Ovarian Reserve
The goal of this observational study is to investigate the distinct tongue manifestation characteristics in patients with diminished ovarian reserve (DOR) compared to healthy individuals, and to clarify the features of tongue…
- Trial name
- CGTCMPDOR (NCT07124260)
- Testing
- gut microbiota, tongue coating microbiota, tongue picture
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University
Meningitis Enterovirus
Characterization of Cytokines Expression During Enterovirus Meningitis in Paediatric Populations.
Enteroviruses (EV) are the most frequent cause of acute meningitis in the paediatric population. Detection of enterovirus in cerebrospinal fluid (CSF) specimens by Polymerase Chain Reaction (PCR) is the gold standard diagnostic…
- Trial name
- Bledi-Cytokine (NCT04711876)
- Testing
- Cytokine level in blood and CSF
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Clermont-Ferrand
Aneurysmal Subarachnoid Hemorrhage, Vasospasm
Transcriptomic Signature of Vasospasm Consecutive to Sub-arachnoid Aneurismal Hemorrhage
Rational: The main danger with intracranial aneurism is its rupture conjugated with subarachnoid hemorrhage (SAH) occurrence. SAH is a severe pathology leading not only to neurological but also extra cerebral disorders.
- Trial name
- NCT01779713
- Testing
- Case-control transcriptomic study
- Where
- France
- Volunteers
- 89 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
PARKINSON DISEASE (Disorder)
Gut Microbiota and Tryptophan Metabolites in Parkinson's Disease
Parkinson's disease is a progressive neurological disorder that can also affect the digestive system. Changes in gut microorganisms and tryptophan metabolites may be associated with Parkinson's disease, but these relationships…
- Trial name
- NCT07749261
- Testing
- Stool Microbiome and Targeted Tryptophan Metabolite Profiling
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ningxia Medical University
Tecfidera, Teriflunomide
Teriflunomide Tecfidera LMCE
This study will investigate the effect of teriflunomide in reducing cortical gray matter (CGM) atrophy and leptomeningeal (LM) inflammation over 24 months compared to dimethyl fumarate (Tecfidera®)
- Trial name
- NCT03526224
- Testing
- Dimethyl Fumarate, Teriflunomide
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University at Buffalo
Pseudotumor Cerebri, Cystinosis
The Role of Susceptibility to Thrombosis in the Pseudotumor Cerebri of Nephropathic Cystinosis: A Case-Control Study
This study will examine whether the tendency to have thrombosis, or the formation of blood clots inside blood vessels, has a role in the development of pseudotumor cerebri (PTC).
- Trial name
- NCT00071903
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Ischemic Stroke
Curative Efficacy of Secondary Prevention for Patients With Ischemic Stroke Through Syndrome Differentiation of TCM
The purpose of this study is to assess the efficacy and safety of Naoxintong Capsule in the secondary prevention of ischemic stroke by the multi-center, randomized,double-blind，placebo-controlled trial design project.
- Trial name
- NCT02334969
- Testing
- Naoxintong Capsule
- Where
- 24 sites in China
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Xiaofei Yu
Parkinson Disease
Neural Correlates of Impulsivity in Idiopathic REM Sleep Behavior Disorder
This study aims to investigate the neural correlates (structural changes, functional connectivity, and structural connectivity of brain structures in prefrontal cortex and basal ganglia) of impulsivity by measuring structures and…
- Trial name
- NCT05353855
- Testing
- No intervention
- Where
- Hong Kong
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Efficacy, Team, Adverse Event
The Immune Assessment of PD-1 Antibody Therapy in Tumor
This retrospective study will leverage previous immune function monitoring results in conjunction with clinical case data at this medical center.
- Trial name
- NCT06693440
- Testing
- PD-1 Inhibitors
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Quanli Gao
Observational Study
The Association of Hormonal Intake and Demographic Factors With Breast Cancer Risk. An Egyptian Case-controlled Study
The aim of the current study is to investigate the association between hormonal intake, occupational and demographic factors, and the risk of breast cancer (BC) among Egyptian females.
- Trial name
- NCT05135013
- Testing
- Dydrogesterone Tablets, Norethisterone acetate, Ethinyl estradiol, Drospirenone and ethinyl estradiol
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- NewGiza University
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