Clinical trials: Case-control Study
Type2diabetes
Effects of Metformin Therapy on Pancreatic and Hepatic Fat Content in Patients of Type 2 Diabetes Mellitus
A sample size of 15 patients with T2DM visiting Fortis C DOC Hospital will be recruited with informed, written consent and will be requested to answer a validated questionnaire in a language known to them (English/Hindi).
- Trial name
- NCT05939921
- Testing
- Metformin
- Where
- India
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Diabetes Foundation, India
Venous Thromboembolism, Liver Transplantation
Risk Factors and a nOmogram of Venous thromboEmbolism in Patients After liveR Transplantation(ROVER Study)
Liver transplantation is currently an effective treatment for end-stage liver disease. The high incidence of thrombotic related complications in the early postoperative period after orthotopic liver transplantation(OLT) has been…
- Trial name
- NCT05209048
- Where
- China
- Volunteers
- 356 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Hepatic Steatosis and Fibrosis in Rheumatoid Arthritis Patients
Hepatic Steatosis and Fibrosis in Rheumatoid Arthritis Patients
studying the prevalence of hepatic steatosis and fibrosis in a large scale of patients with RA and healthy controls
- Trial name
- NCT05679648
- Testing
- ultrasonography
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Indication for Modification of Patient Psychological Status
Psychological Profile of Dental Patients
The objective of this descriptive investigation was to evaluate the psychological profile of dental patients in three levels: global level, the dimensional level, and the discrete symptom level and to compare it with a control…
- Trial name
- NCT02792374
- Testing
- Psychological Measurement
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Talebian, Alireza, M.D.
Asthma
Mechanisms Underlying Asthma Exacerbations Prevented and Persistent With Immune-Based Therapy
Asthma is a growing problem, especially in children. It causes frequent wheezing, shortness of breath, chest tightness, and cough. A cold that is caused by a virus (viral cold) can sometimes make asthma symptoms worse.
- Trial name
- MUPPITS-1 (NCT02502890)
- Where
- 9 sites in United States
- Volunteers
- 208 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Bile Reflux, Gastric Cancer
Associations Among Serum and Gastric Juice Bile Acid Profile, Bile Acid-microbiota Cross-talk in Stomach and the Development of Gastric Cancer
To explore the associations among bile acid profile, bile acid-microbiota cross-talk and the development of gastric cancer, so as to better prevent the occurrence and development of gastric cancer
- Conditions
- Bile Reflux, Gastric Cancer, Precancerous Lesion
- Trial name
- NCT04660058
- Where
- China
- Volunteers
- 73 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Kidney Failure, Chronic
Case-Control Study on Analgesics and Nephropathy (SAN)
The objective of the international, multicenter case-control study was to evaluate the association between end-stage renal disease (ESRD) and use of non-phenacetin-containing analgesics with particular emphasis on combined…
- Trial name
- NCT00302835
- Testing
- non-phenacetin containing analgesics
- Where
- Germany
- Volunteers
- 4,200 people
- Sponsor
- Center for Epidemiology and Health Research, Germany
Suicide, Fatal Suicide
Case Control Psychological Autopsy of Suicide
Suicide is a leading cause of death worldwide, and identifying risk factors has been considered as the key initiative of suicide prevention.
- Conditions
- Suicide, Fatal Suicide, Non Fatal Suicidal Behavior
- Trial name
- NCT05097690
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tamkeen Saleem
Type1diabetes
Metabolic Profiling of Type 1 Diabetes Mellitus in Children and Adolescents
The aim of this study was to look for discriminating variation in the concentrations of small-molecule metabolites in the plasma of T1DM children compared with non-diabetic matched controls using proton nuclear magnetic resonance…
- Trial name
- T1DM (NCT03014908)
- Testing
- Blood sampling
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Hasselt University
COVID-19
Effectiveness of Inactivated COVID-19 Vaccine of the First Booster Dose
This is a retrospective test-negative case-control study of COVID-19 Vaccine (CoronaVac®) manufactured by Sinovac Research and Development Co., Ltd.The main purpose of this study is to measure vaccine effectiveness of homologous…
- Trial name
- NCT05367895
- Testing
- COVID-19 Vaccine (Vero Cell), Inactivated
- Where
- Brazil
- Volunteers
- 14,000 people, healthy volunteers welcome
- Sponsor
- Sinovac Research and Development Co., Ltd.
Spina Bifida
Fecal Microbium Change in Pediatric Patients With Spina Bifida: Prospective Case-control Study
Purpose: In order to verify the hypothesis that the composition of intestinal microbiota in children with spina bifida is different from that of normal control, prospective comparative analysis would be performed.
- Trial name
- NCT04186130
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Chikungunya Virus Infection
Observational Study to Assess the Effectiveness of VLA1553 Vaccine in Preventing Chikungunya During a Pilot Vaccination Strategy in Brazil
This is an observational, non-interventional, test-negative case-control (TNCC) study to estimate the vaccine effectiveness of VLA1553 against Chikungunya virus in a real-world setting.
- Trial name
- NCT07347002
- Testing
- Live-attenuated CHIKV vaccine VLA1553
- Where
- 3 sites in Brazil
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Valneva Austria GmbH
Ketamine Abuse, Psychotic Disorders
Substance Misuse To Psychosis for Ketamine (SToP-K)
Evidence suggests that repeated or chronic ketamine use, as compared to acute ketamine users, posed a higher clinical risk of developing psychotic disorders, potentially related to the underlying chronic N-methyl-D-aspartate…
- Conditions
- Ketamine Abuse, Psychotic Disorders, Substance Use Disorders, Schizophrenia
- Trial name
- NCT03485339
- Testing
- genome testing
- Where
- 2 sites in Hong Kong
- Volunteers
- 162 people
- Sponsor
- The University of Hong Kong
Ventilatory Defect, COVID-19
Visualizing Regional Lung Ventilation in Patients With Postacute-COVID-19
There is a lack of data of spontaneous breathing patients with post-COVID-19 syndrome (PCS) examined by Electrical impedance tomography (EIT). We compare 100 patients with PCS with 50 healthy probands.
- Conditions
- Ventilatory Defect, COVID-19, Post-acute COVID-19 Syndrome, Electric Impedance Tomography
- Trial name
- ViReVentPoCov (NCT05441657)
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Jan-Christoph Lewejohann
Non-Hodgkin's Lymphoma
Interdisciplinary Case-Control Study of Non-Hodgkin's Lymphoma
Non-Hodgkin's lymphoma (NHL) incidence rates have risen three percent per year in the U.S. for four decades. Mortality from NHL has risen 1.6 percent, compared with 0.2 percent for all cancers combined.
- Trial name
- NCT00341952
- Where
- 4 sites in United States
- Volunteers
- 2,378 people
- Sponsor
- National Cancer Institute (NCI)
Seasonal Influenza
A Study of mRNA-1010 Compared With a Licensed Influenza Vaccine in Adults ≥50 Years of Age
The primary objectives of this study are to evaluate the safety and reactogenicity of mRNA-1010, and to evaluate relative vaccine efficacy (rVE) of mRNA-1010 versus an active comparator against reverse transcription polymerase…
- Trial name
- NCT06602024
- Testing
- mRNA-1010, Fluarix®, Influsplit® Tetra
- Where
- 301 sites in United States, Belgium and 9 more
- Volunteers
- 40,805 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Porto-Sinusoidal Vascular Disease
Risk Factors for Portosinusoidal Vascular Disease in Kidney Transplant Recipients:
To look for the factors of exposure present prior to the onset of Porto-Sinusoidal Vascular Disease (PSVD) and which can lead to the occurrence of PSVD after renal transplantation, and therefore to consider the identification of…
- Trial name
- TRANSVAS (NCT05388409)
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Caen
Univentricular Heart
Impact of Exercise Training on Single Ventricle Function in Paediatric Fontan Patients
The goal of this observational study is to learn about how a prescribed Exercise Training Program would affect children living with a Fontan circulation.
- Trial name
- NCT05617534
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- Children's Health Ireland
Glaucoma
OculusGen™ Collagen Matrix Implant for Phaco-Trabeculectomy in Primary Glaucoma: a Case-Control Study
Frequently glaucoma is not controlled with clinical treatment ("eyedrops") or laser surgery to control your eye pressure. If this raised pressure is sustained over a long period of time it can lead to permanent damage to the…
- Trial name
- NCT01027247
- Testing
- Ologen TM
- Sponsor
- Singapore National Eye Centre
Menorrhagia
Construct Validity of a Diagnostic Hysteroscopy Training Model
In a prospective case-control study, the investigators compare the Objective Structured Assessment of Technical Skills (OSATS) scores in medical students and gynecologic experts performing a hysteroscopy on a training model for…
- Trial name
- HSK-2 (NCT02475252)
- Testing
- hysteroscopy on a training model
- Where
- Germany
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
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