Clinical trials: Cataract
Cataract Surgery Anesthesia
Study of Remimazolam for Cataract Surgery
The goal of this clinical trial is to learn if the use of the sedative remimazolam improves the safety of patients having cataract surgery by decreasing the number of sedation-related complications during and after surgery, and…
- Trial name
- NCT07325227
- Testing
- Arm 1 Cataract Surgery performed with remimazolam as sedative, Arm 2 Cataract Surgery performed with standard of care sedative
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fred E, Shapiro
Age-related Cataract
Effects of Holy-Comod and Tears Naturale Forte in Patients After Phaco+IOL
The purpose of the study it to compare the effects of Holy-Comod and Tears Naturale Forte on ocular surface and tear inflammatory mediators in patients after Phaco+IOL.
- Trial name
- NCT02817191
- Testing
- Hylo-Comod eye drop, Tears Naturale Forte eye drop
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Cataract, Astigmatism
A Trial of Toric Versus Non-toric Intraocular Lenses in Phacoemulsification Cataract Surgery
This is a randomised controlled trial that formally compares intra-ocular lenses, which can be used in cataract surgery, one of which is the standard 'monofocal' lens, and the other is the newer toric lens which can correct…
- Trial name
- NCT01712503
- Testing
- Phacoemulsfication cataract surgery and intra-ocular lens implant
- Where
- United Kingdom
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Western Sussex Hospitals NHS Trust
Cataracts, Retina Surgery
Eye Drop Application Monitor, Pilot Study
The purpose of this study is to determine if an eye drop video monitoring device can accurately assess (as compared to a patient's own log or a proprietary software) the exact amount and time of eye drop delivery to a patient's…
- Conditions
- Cataracts, Retina Surgery, Glaucoma, Any Condition That Requires Ophthalmic Drops
- Trial name
- NCT02639845
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Alexander Eaton
Cataract
Assessment of Visual Performance Combining a Symfony IOL and a +3.25 Tecnis Multifocal IOL
This will be a single center, non comparison clinical trial. Fifty study patients will have the Symfony IOL implanted in their dominant eye and a +3,25D Tecnis Multifocal in their non-dominant eye.
- Trial name
- NCT02847572
- Testing
- Cataract Surgery
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Crystal Clear Vision
Visual Impairment, Hearing Loss
Survey of Sensory Impairment Indicators Among Adults Aged 65 Years and Older in Xinxing County
This cross-sectional population-based survey will be conducted among residents aged 65 years and older in Xinxing County, Yunfu, Guangdong Province, China.
- Conditions
- Visual Impairment, Hearing Loss, Dual Sensory Impairment, Cataract
- Trial name
- NCT07694505
- Where
- China
- Volunteers
- 2,854 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Ophthalmic
Bispectral Index Monitoring In Pediatric Cataract Surgery: A Comparative Study Using Propofol-Midazolam Versus Sevoflurane Anesthesia
Ocular alignment will be studied in children having cataract surgery that will be divided into two groups, one group will be anesthetized using sevoflurane anesthesia (group A), and the other will be anesthetized by midazolam…
- Trial name
- NCT05262205
- Testing
- measuring depth of anesthesia and its relation to the globe
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Refractive Errors, Cataract
Xinxing Eye Cohort Study
To establish the baseline levels and monitor the progress of two newly introduced global eye health indicators in Xinxing County, including effective refractive error coverage (eREC) and effective cataract surgery coverage…
- Trial name
- NCT07257536
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Macular Degeneration, Diabetic Retinopathy (DR)
Artificial Intelligence-assisted Diagnosis in Ophthalmology
This is a retrospective, multicenter, observational study designed to develop and validate an artificial intelligence (AI) system capable of detecting and classifying major ophthalmic diseases (glaucoma, cataract, diabetic…
- Conditions
- Macular Degeneration, Diabetic Retinopathy (DR), Glaucoma, Keratoconus
- Trial name
- AI-OPHTH-CR (NCT07497815)
- Testing
- No interventions
- Where
- 2 sites in Costa Rica
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Marisse Masis-Solano
Cataract
Clinical Investigation of Omega Refractive Capsule, Model VI
The objective of this study is to evaluate the safety and effectiveness of the investigational Omega Refractive Capsule (model VI)
- Trial name
- ORCVI (NCT04574115)
- Testing
- Omega Refractive Capsule with an FDA approved Intraocular Lens, FDA approved Intraocular Lens
- Where
- Costa Rica
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Omega Ophthalmics
Cataract
Risk of Radiation-induced Cataracts Among Interventional Cardiology Staff
The goal of the present study is to evaluate the prevalence of radiation-associated lens opacities among interventional cardiology staff members (such as physicians, technicians, and nurses) and determine its association with…
- Trial name
- IC-CATARACT (NCT02837562)
- Testing
- Slit lamp eye examination
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Glaucoma, Glaucoma, Open-Angle
Prevalence of Glaucoma and Normative Data of Ocular Biometry in Elderly Population in Bangkok
The BANMOP eye study is an ophthalmic subproject of the Bangkoknoi Model Project (BANMOP), a community-based initiative integrating electronic health databases with population surveys to sup-port context-specific health promotion…
- Conditions
- Glaucoma, Glaucoma, Open-Angle, Glaucoma, Suspect, Glaucoma, Angle-Closure
- Trial name
- BANMOP (NCT07763288)
- Where
- Thailand
- Volunteers
- 1,470 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Astigmatism
Prospective Evaluation of the Effectiveness of the Femtosecond Laser-assisted Refractive Astigmatic Keratotomy.
This clinical phase IV study is an open, prospective phase IV study and acts to evaluate the effectiveness of the femtolaser-assisted astigmatic keratotomy.
- Trial name
- NCT01885780
- Testing
- Laser-assisted Astigmatic keratotomy
- Where
- Czechia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Technolas Perfect Vision GmbH
Glaucoma, Diabetic Retinopathy (DR)
"My Eyes, My Light": Amar Chokh, Amar Alo
Eye disease affects 2.2 billion people globally, which in turn adversely affects schooling, economic productivity, and participation in social life.
- Conditions
- Glaucoma, Diabetic Retinopathy (DR), Hypertensive Retinopathy, Cataract
- Trial name
- ACA2 (NCT07135570)
- Testing
- Multimodal Screening for Eye Disease, cataract surgery
- Where
- Bangladesh
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Data Yakka, Inc.
Congenital Cataract
Analysis of Retinal Nerve Fiber Layer and Macular Thickness After Congenital Cataract Surgery
Congenital cataract is the main cause of form deprivation amblyopia in children. Current studies confirm that form deprivation amblyopia affects the retinal nerve fiber layer.
- Trial name
- NCT03621579
- Testing
- cataract surgery
- Where
- 2 sites in China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Refractive Error, Cataract
Vision Measured by the Vimetrics CVA Compared With Chart Testing Under Similar Luminance and Contrast Conditions
Purpose of The Study: The purpose of this study is the following: A)To gather age-related normative visual acuity data for the Vimetrics Central Vision Analyzer (CVA, Vimetrics, LLC, Media, Pa) B)To gather visual acuity data for…
- Conditions
- Refractive Error, Cataract, Maculopathy
- Trial name
- NCT02028351
- Where
- 2 sites in United States, Austria
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sinclair Technologies, LLC
Cataract and IOL Surgery
Comparing Visual Outcomes in Matched Patients Receiving a Low Cylinder Power Toric IOL or a Non-toric IOL
The purpose of the study is to determine if visual function is improved with implantation of a low-cylinder toric intraocular lens, relative to a non-toric intraocular lens.
- Trial name
- NCT06717607
- Testing
- low cylinder toric IOL, non-toric IOL implantation
- Where
- Norway
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Ifocus Oyeklinikk
Cataract, Shallow Anterior Chamber
Assessment Of Anterior Chamber Configuration Changes After Phacoemulsification
To investigate changes in anterior chamber angle configuration after phacoemulsification and intraocular lens (IOL) implantation with Swept-Source Optical Coherence Tomography (SS-OCT).
- Conditions
- Cataract, Shallow Anterior Chamber, Narrow Angle
- Trial name
- AOACCCAP (NCT02238002)
- Testing
- cataract surgery
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Zheng Qian
Dry Eye Syndromes, Cataract
Metabolomic Profile in Dry Eye Syndrome Patients.
The primary objective is to determine possible implications of deviant tear film quality for optimal refractive precision in patients scheduled for cataract surgery.
- Trial name
- NCT05433428
- Testing
- Lubricant Eye Drops, Preservative Free, Preservative
- Where
- Norway
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Ifocus Oyeklinikk
Cataract, Diabetic Retinopathy
Diabetic Retinopathy and OCT-A Changes Post-cataract Surgery
The purpose of this study is to use optical coherence tomography angiography (OCT-A) to compare retinal vasculature after uncomplicated cataract surgery in patients with and without diabetic retinopathy.
- Conditions
- Cataract, Diabetic Retinopathy, Macular Edema Due to Diabetes Mellitus
- Trial name
- NCT04660006
- Testing
- Cataract surgery
- Where
- Canada
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Uptown Eye Specialists