Clinical trials: Cataract Surgery, active
Dry Eye, Ocular Surface Disease
Evaluation of Lacrifill
Dry Eye Disease is defined as "a multifactorial disease of the tears and ocular surface that results in symptoms of discomfort, visual disturbance, and tear film instability with potential damage to the ocular surface.
- Conditions
- Dry Eye, Ocular Surface Disease, Cataract Surgery, Eyes Dry Feeling of
- Trial name
- NCT07796178
- Testing
- Lacrifill, Saline
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Eye Research Associates, LLC
Aphakia, Presbyopia
Contralateral Claims Study of Clareon Vivity Pro
The purpose of this study is to test new versions of Clareon Vivity Pro intraocular lenses (IOLs) by comparing them to currently marketed IOLs.
- Trial name
- NCT07484191
- Testing
- Clareon Vivity Pro IOL, Clareon Vivity IOL, TECNIS PureSee IOL
- Where
- 7 sites in Australia
- Volunteers
- 165 people
- Sponsor
- Alcon Research
Cataract, Fuchs Endothelial Corneal Dystrophy
Partial Range Of Field IOLs in DMEK-Enabled Procedures
Study Overview This study aims to evaluate the visual outcomes, quality of vision, and patient satisfaction after receiving an extended range PRoF intraocular lens (IOL) during triple Descemet Membrane Endothelial Keratoplasty…
- Trial name
- PROFIDE (NCT07441616)
- Testing
- combined cataract and lamellar endothelial keratoplasty
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Universitair Ziekenhuis Brussel
Dry Eye Syndrome
Efficacy of Warm Compress Therapy in Enhancing Tear Film Quality and Reducing Postoperative DES
Dry eye disease (DED) is a multifactorial condition often exacerbated by cataract surgery, leading to discomfort and visual disturbances.
- Trial name
- NCT06914232
- Testing
- Warm Compress, Standard Care
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Superior University
Glaucoma, Cataract
Evaluation of Microinvasive Glaucoma Surgery: MINIject® Versus Hydrus® Microstent in Combination With Cataract Surgery
The study aims to investigate postoperative outcomes after two different MIGS implants (MINIject or Hydrus) in combination with cataract surgery for patients with glaucoma.
- Trial name
- MINHY (NCT06844292)
- Testing
- MINIject with Cataract Surgery, Hydrus Microstent with Cataract Surgery
- Where
- Austria
- Volunteers
- 152 people
- Sponsor
- Medical University of Graz
Visual Impairment, Hearing Loss
Survey of Sensory Impairment Indicators Among Adults Aged 65 Years and Older in Xinxing County
This cross-sectional population-based survey will be conducted among residents aged 65 years and older in Xinxing County, Yunfu, Guangdong Province, China.
- Conditions
- Visual Impairment, Hearing Loss, Dual Sensory Impairment, Cataract
- Trial name
- NCT07694505
- Where
- China
- Volunteers
- 2,854 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract Surgeries
Comparison of the Concordance Between Digital Marking and Manual Marking for Toric Intraocular Lens Positioning
This cross-sectional comparative study evaluated patients from a single cataract center. In each eye, manual horizontal meridian axis line was marked on the cornea using the manual peripheral corneal marking technique (Horizontal…
- Trial name
- NCT07710963
- Testing
- Verion Digital Marking
- Volunteers
- 100 people
- Sponsor
- Thammasat University
Endothelial Cell Loss, Corneal, Cataract and Intraocular Lens (IOL) Surgery
Effect of Vitamin C Supplementation in Corneal Endothelial Damage in Phacoemulsification of Patients with Hard Cataracts
The goal of this clinical trial is to analyze the protective effects of oral ascorbic acid on the corneal endothelial layer undergoing oxidative stress due to phacoemulsification in patients with hard cataracts.
- Trial name
- NCT06781970
- Testing
- Oral Vitamin C
- Where
- 2 sites in Indonesia
- Volunteers
- 120 people
- Sponsor
- Universitas Indonesia
Lens Diseases
Evaluating Presbyopia-Correcting IOLs in Complex Cataract Cases With Anterior Segment Abnormalities
The goal of cataract surgery has evolved from simply restoring sight to providing clear and comfortable full-range vision. Traditionally, monofocal IOLs remain the routine choice for special cases with anterior segment…
- Trial name
- NCT07321756
- Testing
- Unilateral Posterior Chamber Implantation of Presbyopia-Correcting IOL, Unilateral Posterior Chamber Implantation of Monofocal IOL
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
OAG - Open-Angle Glaucoma
Clinical Trial to Evaluate the Safety and Effectiveness of a Canaloplasty Device in Subjects With Open-Angle Glaucoma
Clinical Trial to Evaluate the Safety and Effectiveness of a Canaloplasty Device in Subjects with Open-Angle Glaucoma
- Trial name
- NCT05696561
- Testing
- Canaloplasty Device
- Where
- 3 sites in Chile, Costa Rica and 1 more
- Volunteers
- 70 people
- Sponsor
- New World Medical, Inc.
Cataract, Endothelial Cell Loss, Corneal
Safety and Tolerability of EO2002
The goal of this clinical study is to assess the safety of intracameral injection of EO2002 in subjects post-cataract surgery.
- Trial name
- NCT05587205
- Testing
- EO2002
- Where
- Mexico
- Volunteers
- 32 people
- Sponsor
- Asociación para Evitar la Ceguera en México
Dry Eye Disease (DED), Cataract Surgery
POST CATARACT SURGERY DRY EYE DISEASE
Cataract surgery is one of the most frequent and successful interventions currently undertaken in medicine. However, a significant number of patients who underwent cataract surgery still complain about postoperative symptoms…
- Trial name
- NCT07715266
- Testing
- NOX-01
- Where
- 2 sites in Spain
- Volunteers
- 33 people
- Sponsor
- NOXELIS
Cataract
Comparing Monofocal IOLs in Highly Myopic Cataract Patients
Comparison of Postoperative Outcomes in Patients with High Myopia Undergoing Cataract Surgery Implanted with Extended Depth of Focus Intraocular Lens (ICB00) and Monofocal Intraocular Lens (ZCB00)
- Trial name
- NCT06905938
- Testing
- no intervention
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wenzhou Medical University
Eye Disorders, Cataract Extraction
Effectiveness of a Large Language Model-Based Educational Tool on Intraocular Lens Options
Patients with cataracts disease need to choose what type of artificial lens will go into their eye prior to surgery date. Some lenses are standard and are usually covered by insurance.
- Conditions
- Eye Disorders, Cataract Extraction, Cataract and IOL Surgery, Cataract Surgery Experience
- Trial name
- NCT07317661
- Testing
- LLM-based Education
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Stanford University
Primary Open Angle Glaucoma, Cataract
A Study of the Helix Surgical System in Primary Open-Angle Glaucoma (POAG) and Cataract (HELIX)
A study to assess the safety of the Helix Surgical System in cataract surgery and to gain early evidence of its effectiveness in lowering intraocular pressure (IOP) in subjects with mild to moderate primary open-angle glaucoma…
- Trial name
- HELIX (NCT06948773)
- Testing
- Helix Surgical System
- Where
- Panama
- Volunteers
- 25 people
- Sponsor
- Sight Sciences, Inc.
Cataract Patients, Cataract After Surgery
Evaluation of the Effects of Education and Counseling Provided to Patients Via Distance Nursing After Cataract Surgery on Regular Use of Medications and Patient Satisfaction. CAT-TELEMED (Cataract - Telemedicine) TNCat-25 (Tele-Nursing Cataract - 2025)
This randomized controlled study aims to investigate the effects of tele-nursing-based education and counseling on medication adherence and patient satisfaction following cataract surgery.
- Conditions
- Cataract Patients, Cataract After Surgery, Cataract Surgery
- Trial name
- TELE-NURSİNG (NCT07262866)
- Testing
- Structured Tele-Nursing Education and Counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Züleyha Sönmez
Epiretinal Membrane, Macular Edema (ME)
Minimal Vitrectomy Surgery for Epiretinal Membrane
This multicenter randomized controlled trial evaluates Minimal Vitrectomy Surgery (MVS) versus conventional vitrectomy for idiopathic epiretinal membrane (ERM).
- Conditions
- Epiretinal Membrane, Macular Edema (ME), Nuclear Cataract
- Trial name
- MVS-ERM (NCT07019896)
- Testing
- Minimal Vitrectomy Surgery, Conventional Vitrectomy
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Peking Union Medical College Hospital
Cataract, Cataract Senile
Impact of a Novel Extended Depth of Focus Intraocular Lens on Visual and Lifestyle Enhancement
The introduction of presbyopia-correcting intraocular lenses (PC-IOLs) has provided cataract and refractive surgeons the ability to provide patients with a wider range of visual success and spectacle independence post-cataract…
- Conditions
- Cataract, Cataract Senile, Presbyopia
- Trial name
- NCT04570579
- Testing
- Vivity Extended Depth of Focus Intraocular Lens
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Alanna Nattis, DO
Cataract
Assessment of Visual Function and Optics in Intraocular Lenses
The main objective of this research is to assess visual function and optical performance of CE marked, implanted intraocular lenses to understand the individual factors that affect their performance and how these may be improved…
- Trial name
- NCT01654159
- Testing
- Monofocal IOL, Multifocal IOL, Toric IOL
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- Aston University
Cataract
Registry of PHAcoemulsification for Cataract Surgery
Cataracts cause vision loss due to opacities in the lens. Cataract surgery is performed by emulsifying the nucleus of the lens. A phacoemulsifier is the machine used to deliver ultrasonic energy in the eye to fragment the lens…
- Trial name
- ROPHACS (NCT06659419)
- Where
- France
- Volunteers
- 100,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris