Clinical trials: Cathartics
Chronic Constipation
Effect of PEG, Bisacodyl and Prucalopride on Colonic Motility in Healthy Subjects
This study aim was to evaluate the effect of pharmacological treatments normally used to treat functional constipation and in particular PEG, bisacodyl and prucalopride on colonic motility as assessed by high-resolution manometry.
- Trial name
- NCT03279341
- Testing
- polyethylene glycol, Bisacodyl, Prucalopride
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Constipation
Laxative Properties of Microencapsulated Lipid (Constipation Study)
The present study seeks to build on these observations to assess whether in principle, fat containing microcapsules might help patients experiencing constipation in association with weight loss interventions (including GLP-1…
- Trial name
- NCT05324241
- Testing
- Fat Microcapsules
- Where
- Ireland
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Colonoscopy
Effect of Lactulose and/or Polyethylene Glycol Solution for Bowel Preparation for Colonscopy Procedures
Colonoscopy is the most useful exam used to evaluate colorectal diseases, like colorectal polyps and cancer. The appropriate bowel preparation is indispensable for colonoscopy procedures.
- Trial name
- NCT05076799
- Testing
- 100 ml lactulose combined with 1 L PEG, 100 ml lactulose combined with 2 L PEG, 200 ml lactulose
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sichuan University
Chronic Constipation
Effect to Linaclotide on Colonic Motility
This study aim was to evaluate the effect of Linaclotide, a pharmacological treatment normally used to treat functional constipation or irritable bowel syndrome with predominant constipation, on colonic motility as assessed by…
- Trial name
- NCT06989268
- Testing
- Linaclotide 290 micrograms
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven