Clinical trials: Catheter Thrombosis
Acute Ischemic Stroke
Safety and Efficacy Evaluation of the Ceretrieve Device in the Treatment of AIS Patients
The main objective of this clinical trial is to evaluate of the safety \& efficacy of the Ceretrieve device within 24 hours post thrombectomy procedure.
- Trial name
- NCT06733246
- Testing
- Aspiration 0
- Where
- Germany
- Volunteers
- 132 people
- Sponsor
- Ceretrieve Ltd.
Pulmonary Embolism
Endovascular Engineering ENGULF Study
Evaluation of initial safety and clinical feasibility of the Hēlo PE Thrombectomy System for thrombectomy in acute submassive pulmonary embolism (PE).
- Trial name
- ENGULF (NCT05597891)
- Testing
- Hēlo PE Thombectomy System
- Where
- 21 sites in United States
- Volunteers
- 177 people
- Sponsor
- Endovascular Engineering
Pediatric Venous Thromboembolism
Risk Factors for Thrombosis in Children With Central Venous Lines
This project addresses the role of lab markers around the time of central line placement in predicting risk of thrombosis in pediatric patients with central venous lines being placed.
- Trial name
- NCT04117217
- Testing
- Labs drawn
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Arizona
Patients Indicated for a PICC for Any Medical Condition
The PROOF Study: The PICC Related Obstruction Of Flow Study
The main purpose of this study is to confirm whether the AngioDynamics BioFlo™ Peripherally Inserted Central Catheter (PICC) is associated with less formation of blood clots compared to another commercially available PICC.
- Trial name
- PROOF (NCT01921114)
- Testing
- BioFlo™ Peripherally Inserted Central Catheter (PICC), Bard® Dual-Lumen PowerPICC SOLO2®
- Where
- 5 sites in United States, Canada and 1 more
- Volunteers
- 57 people
- Sponsor
- Angiodynamics, Inc.
Central Line Complication
Incidence and Risk Factors of Central Line Catheter Related Thrombosis
Central venous catheters are frequently used for monitoring haemodynamic status and rapidly delivering fluid therapy during the peri- and postoperative periods.
- Trial name
- NCT03450785
- Testing
- ultrasound examination
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Central Venous Catheter Thrombosis, Central Venous Catheter Associated Bloodstream Infection
t-PA Prophylaxis to Prevent Catheter-associated Thrombosis and Infection
The purpose of this pilot study is to test feasibility of concept, consent and enrollment rates, and mechanics of study designed to assess if intra-catheter dwells of tissue plasminogen activator (t-PA) is effective in decreasing…
- Trial name
- TOPCAT (NCT03672006)
- Testing
- alteplase (recombinant t-PA), Heparin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin
Hemodialysis, Tunneled Catheter, Qatar
Management of Tunneled Catheter Thrombosis in Hemodialysis Patients: Prospective Study From Qatar
Goal of the study: A- To find out the best protocol for catheter lock solution to decrease the prevalence of catheter thrombosis 1. - The time to first episode of catheter thrombosis lead to catheter change. 2.
- Trial name
- NCT02868697
- Testing
- TauroLock U 25000, (TauroLock Hep500)
- Where
- Qatar
- Volunteers
- 170 people
- Sponsor
- Hamad Medical Corporation
Vascular Access Complication, Vascular Access Related Infection
Arrow Chloragard Peripherally-Inserted Central Catheters (PICC) Study
A prospective study evaluating the timing, incidence and relationship of commonly occurring complications related to the use of peripherally-inserted central catheters.
- Trial name
- NCT03019302
- Testing
- Arrow PICC with Chloragard Technology
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Teleflex
Catheter Related Complication
Central Venous Catheter-Related Thrombosis in Critically Ill Patients
This project aims to identify catheter-related thrombosis (CRT) and determine its incidence, associated factors, and outcomes. The eligible patients will undergo daily ultrasound just distal to the central venous catheter…
- Trial name
- CVC-RT (NCT06573112)
- Testing
- ultrasound assessment for catheter-related thrombosis.
- Where
- Oman
- Volunteers
- 315 people
- Sponsor
- Sultan Qaboos University
Hemodialysis Catheter Complication, Catheter Thrombosis
Hemodialysis Catheter Complications in the Emergency Department Versus Hemodialysis Unit
This prospective observational cohort study was designed to compare the risk of catheter thrombosis and catheter-related infection between adult patients who underwent temporary hemodialysis catheter insertion in the emergency…
- Conditions
- Hemodialysis Catheter Complication, Catheter Thrombosis, Catheter-Related Infections, Hemodialysis Vascular Access
- Trial name
- NCT07645365
- Where
- Turkey (Türkiye)
- Volunteers
- 398 people
- Sponsor
- Antalya Health Sciences University
Catheters, Indwelling, Thrombosis
A Randomized Evaluation of the Effect of Routine Normal Saline Flush Versus Heparinized Saline Solution in Groshong and Groshong PICC Catheters
The Groshong and Groshong PICC catheters are popular venous access devices because they are maintained with only weekly saline flushes.
- Trial name
- NCT00001518
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Blood Clots, Vascular Disease
Single Center Post-Market Study of Thrombolytic Therapy Using the Versus™ Catheter
Assess the functionality of the Versus Catheter for catheter-directed thrombolysis of pulmonary blood clots, including advanced imaging assessment.
- Conditions
- Blood Clots, Vascular Disease, Embolism Thrombosis, Cardiovascular Diseases
- Trial name
- NCT06975969
- Testing
- Versus™ Endovascular Pulmonary Artery Drug Delivery Catheter
- Where
- United States
- Sponsor
- Liquet Medical Inc.
Adult Cancer Patients, Right Atrial Clot
A Study of Cardiac Magnetic Resonance Imaging (CMR) for Evaluating Catheter-Associated Right Atrial Clot in People With Cancer
The researchers are doing this study to see how well cardiac magnetic resonance imaging (CMR) scans can be used to examine the properties of central venous catheter-associated right atrial clot (RA clot).
- Trial name
- NCT07549477
- Testing
- Cardiac MRI
- Where
- 7 sites in United States
- Volunteers
- 150 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Acute Ischemic Stroke, Large Vessel Occlusion
Proximal TEmporary oCclusion Using Balloon Guide Catheter for Mechanical Thrombectomy
A multi-center, prospective, randomized, open-label, blinded endpoint assessment (PROBE) clinical trial of endovascular treatment among selected AIS.
- Conditions
- Acute Ischemic Stroke, Large Vessel Occlusion, Thrombectomy, Thrombosis
- Trial name
- PROTECT-MT (NCT05592054)
- Testing
- Balloon guide catheters (BGCs), Standard guide catheter
- Where
- China
- Volunteers
- 329 people
- Sponsor
- Changhai Hospital
Infant, Premature, Anticoagulants
Heparin Versus no Heparin on Duration of Peripherally Inserted Central Catheter (PICC) Patency in Neonates
Background: Heparin is an anticoagulant commonly used in the neonatal population as a means to prevent catheter related occlusion and malfunction by thrombosis (clot).
- Conditions
- Infant, Premature, Anticoagulants, Thrombosis
- Trial name
- NCT00879957
- Testing
- heparin, No heparin
- Where
- United States
- Sponsor
- The University of Texas Health Science Center at San Antonio
Thrombosis
Safety and Efficacy of a Single Dose of Gruticibart to Prevent CRT
This phase II trial studies how well gruticibart works in reducing the incidence of catheter-related thrombosis (CRT) blood clots in patients with a central venous catheter (CVC) inserted.
- Trial name
- NCT07498517
- Testing
- Gruticibart, Ultrasound, Biopspecimen collection
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- OHSU Knight Cancer Institute
Central Line-Associated Bloodstream Infection (CLABSI), Venous Thromboembolism
Patient Safety Learning Laboratory: Making Acute Care More Patient-Centered
The Brigham and Women's Hospital (BWH) Patient Safety Learning Laboratory (PSLL) focuses on developing health information technology (HIT) tools to engage patients, family, and professional care team members in reliable…
- Conditions
- Central Line-Associated Bloodstream Infection (CLABSI), Venous Thromboembolism, Patient Fall, Catheter-Associated Infection
- Trial name
- PSLL (NCT02969343)
- Testing
- Patient Safety health information technology
- Where
- United States
- Volunteers
- 21,000 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Portal Vein Thrombosis
Portal Vein Thrombosis in Neonate With Umbilical Catheter
The aim of this study is to identify incidence of portal vein thrombosis after umbilical catheter and to identify the risk factor of this condition ,location of PVT and prognosis of PVT.
- Trial name
- NCT06150807
- Testing
- ultrasound and doppler
- Volunteers
- 45 people
- Sponsor
- Assiut University
Mechanical Ventilation Complication, Arterial Thrombosis
Pragmatic Randomized Trial for Arterial Catheters in the Critical Care Environment
Investigators will conduct a pragmatic randomized trial to investigate the non-inferiority of restricted use of invasive arterial lines compared to standard arterial line use.
- Conditions
- Mechanical Ventilation Complication, Arterial Thrombosis, Limb Ischemia, Shock
- Trial name
- GRACE (NCT05411315)
- Testing
- Restricted-use of arterial catheter, Standard-use of arterial catheter
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Deep Vein Thrombosis
Coagulation Changes in Trauma Patients
Hypothesis to be tested: placement of a central venous catheter will induce a systemic hypercoagulable state. To determine this, the investigators will measure thromboelastography (TEG), PT(prothrombin time), PTT (partial…
- Trial name
- NCT00795743
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Miami