Clinical trials: Catheter-Related Blood Stream Infection
Upper Extremity Deep Vein Thrombosis
Major Complications Related to PICC and Midline Insertion
Most important peripherally inserted central catheter (PICC) and Midline complications are thrombosis and catheter related blood stream infections.
- Trial name
- PICC/MIDLINE (NCT02489721)
- Testing
- PICC and Midline
- Where
- Italy
- Volunteers
- 547 people
- Sponsor
- Azienda Ospedaliera S. Maria della Misericordia
Catheter Related Blood Stream Infections, Intestinal Failure
Clinical Trial Comparing TaurolockTMHep100 (Taurolidine 1.35%) and 0.9% Saline As Prevention of Recurrent Catheter-related Bloodstream Infections
The purpose of the trial is to compare two catheter lock solutions (active: 1.35% taurolidine and placebo: 0.9% saline), on the occurence of catheter related blood stream infection, in patients with intestinal failure and a…
- Trial name
- NCT06660641
- Testing
- TaurolockTMHep100, 0.9 % saline
- Where
- Denmark
- Volunteers
- 61 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
End Stage Renal Disease
Analysis of CRBSI Rates in Patients With a NexSite™ HD (Hemodialysis) Catheter
A U.S. multi-centre post approval registry to analyse the CRBSI rate in patients with the NexSite HD Catheter for long term vascular access for hemodialysis.
- Trial name
- NCT02453646
- Testing
- NexSite HD Patients
- Where
- 6 sites in United States
- Volunteers
- 120 people
- Sponsor
- Marvao Medical
Nosocomial Infections
Multi-center Observational Study to Evaluate Epidemiology and Resistance Patterns of Common ICU-Infections (MOSER)
Most literature on ICU infections and the resistant patterns comes from the western literature. This data may not truly reflect the incidence, epidemiology and resistance patterns in developing countries such as India.
- Trial name
- MOSER (NCT01346735)
- Testing
- No intervention
- Where
- India
- Volunteers
- 381 people
- Sponsor
- Indian Society of Critical Care Medicine
Hemodialysis Catheter-Associated Bacteremia, Hemodialysis Complication
Ethanol Lock and Risk of Catheter Related Blood Stream Infection in Patients With Haemodialysis Catheter
The aim of this study is to examine the effect of ethanol (70%) as lock-solution after hemodialysis on: The frequency of dialysis catheter-related bacteremia among patients under observation of potential complications Other…
- Trial name
- NCT05953675
- Testing
- Ethanol 70%, Isotonic saline with heparin
- Where
- Denmark
- Volunteers
- 280 people
- Sponsor
- Zealand University Hospital
Ventilator Acquired Pneumonia, Catheter Related Blood Stream Infections
Ontario ICU Clinical Best Practices Demonstration Project
The pragmatic issue at hand how to get physicians and nurses to use best practices… and how to measure consequences of their implementation.
- Conditions
- Ventilator Acquired Pneumonia, Catheter Related Blood Stream Infections, Pressure Ulcer Prophylaxis, DVT Prophylaxis
- Trial name
- NCT00332982
- Testing
- Focused knowledge translation strategies
- Where
- Canada
- Sponsor
- Sunnybrook Health Sciences Centre
Catheter-related Bloodstream Infection
SQ53 Disinfectant Wipes for Prevention of CRBSI
SQ53 is a novel antimicrobial, sporicidal solution that is based on a platform of quaternary ammonium chloride compounds. It has been tested against a wide range of bacteria, viruses, spores and fungal pathogens.
- Trial name
- NCT04822467
- Testing
- SQ53 Wipe, Ethanol Wipe
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- The Cleveland Clinic
Catheterization, Infection
Trial on the Efficacy of Tegaderm Chlorhexidine Gluconate (CHG) in Reducing Catheter Related Bloodstream Infections
TegaCHG is a multicentric randomized study aimed at evaluating the possibility that the use of TegaDerm CHG dressing may reduce the incidence of catheter related blood stream infections (CRBSI).
- Trial name
- TegaCHG (NCT01142934)
- Testing
- Transparent adhesive dressing with an integrated gel pad containing 2% w/w chlorhexidine gluconate (CHG) (TegaDerm CHG)
- Where
- 8 sites in Italy
- Volunteers
- 1,200 people
- Sponsor
- Catholic University of the Sacred Heart
Blood Stream Infections, Short Bowel Syndrome
Evaluation of 70% Ethanol Lock Solution to Prevent Catheter Related Blood Stream Infections in Pediatric Patients
The purpose of this study is to evaluate the clinical practice of the prophylactic use of ethanol locks for the prevention of catheter related blood stream infections in pediatric intestinal rehabilitation program patients…
- Trial name
- NCT01409772
- Testing
- Ethanol Lock
- Sponsor
- University of Nebraska
Bloodstream Infection
Antimicrobial Catheter Securement Dressings for the Prevention of Cvc-related Bloodstream Infections in Cancer Patients
In neutropenic cancer patients, catheter-related bloodstream infections may cause severe infections and even death. To assess the prophylactic effect of a chlorhexidine coated catheter securement dressing on the incidence of…
- Trial name
- COAT (NCT01544686)
- Testing
- 3M™ Tegaderm™ CHG IV and 3M™ Tegaderm™ Advanced IV
- Where
- 5 sites in Germany
- Volunteers
- 630 people
- Sponsor
- University of Cologne
Catheter-Related Infections
Pediatric Ethanol Lock Therapy Study.
This study is a double-blind crossover design to compare prophylaxis with ethanol lock therapy versus placebo lock therapy (heparin).
- Trial name
- NCT00948441
- Testing
- 25% ethanol, heparin lock
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Pittsburgh
Lock Solution, Catheter Related Blood Stream Infections
Randomized, Multicenter, Double-blind, Vancomycin-controlled Study to Evaluate the Efficacy of Ethanol Lock Solution for the Curative Treatment of Implantable Venous Access Port Infection Due to Coagulase-negative Staphylococci
Implantable venous access port infections are mainly due to coagulase negative staphylococci and may be managed by antibiotic lock therapy with retention of the port. Most of the time a vancomycin lock is used.
- Conditions
- Lock Solution, Catheter Related Blood Stream Infections, Central Venous Catheter Infection, Intravenous Drug Delivery Systems
- Trial name
- Etha-LOCK (NCT02411331)
- Testing
- Ethanol 40% + Enoxaparine 400UI/ml, Vancomycine 5 mg/ml + Héparine 2500UI/ml
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Clermont-Ferrand
Catheter Related Blood Stream Infection
Long-term Hemodialysis Catheter Removal and Delayed Replacement, Versus Exchange Over a Guidewire to Treat Catheter Related Blood Stream Infection
Prospective, randomized Study of tunneled cuffed hemodialysis catheter removal and delayed replacement, versus exchange over a guidewire to treat catheter related blood stream infection
- Trial name
- NCT03054714
- Testing
- catheter replacement
- Volunteers
- 798 people
- Sponsor
- Ain Shams University
Catheter Related Blood Stream Infections
Clinical Trial With Catheter Locking TauroSept® (Taurolidine 2%) or Saline Solution 0,9%
The purpose of this study is to determine if TauroSept® taurolidine 2% is more efficient than saline solution 0.9% as a catheter lock solution in preventing catheter related blood stream infections in patients with home…
- Trial name
- NCT01826526
- Testing
- TauroSept®
- Where
- 7 sites in Denmark, Germany and 4 more
- Volunteers
- 105 people
- Sponsor
- Geert Wanten
Catheter-Related Infections
Comparison of Chlorhexidine Impregnated Dressing and Standard Dressing
Investigators have designed a single-center randomized controlled trial to compare chlorhexidine gluconate (CHG)-impregnated dressing and standard dressing with respect to their effects on the infection outcomes.
- Trial name
- NCT04794231
- Testing
- Standard dressing, Chlorhexidine gluconate -impregnated dressing group
- Where
- Turkey (Türkiye)
- Volunteers
- 307 people
- Sponsor
- Istanbul Medeniyet University
End Stage Renal Disease
A Multi-Centered, Two-Arm, Randomized Study Comparing the Effects of AAT-023 (Zuragen) Solution, and Heparin on the Incidence of Catheter Related Blood Stream Infections in Tunneled Chronic Central Venous Catheters for Dialysis
The purpose of this study is to determine if AAT-023 (Zuragen) solution is superior to Heparin in preventing Catheter Related Blood Stream Infections for End Stage Renal Disease patients.
- Trial name
- NCT00628680
- Testing
- AAT-023 solution (Zuragen), Heparin
- Where
- 22 sites in United States
- Volunteers
- 415 people
- Sponsor
- Ash Access Technology
Infection, Hospital, Antimicrobial
Hydrogen Peroxide and Ultraviolet Light for Disinfecting Surfaces in Intensive Care Units
Healthcare-associated infections (HAIs) remain a major problem in intensive care units (ICUs), driven by environmental contamination with multidrug-resistant organisms that persist despite routine manual cleaning.
- Conditions
- Infection, Hospital, Antimicrobial, Pneumonia Associated With Mechanical Ventilation, Urinary Tract Infection(UTI)
- Trial name
- Hylight (NCT07233837)
- Testing
- Aerosol of hydrogen peroxide, Irradiation of ultraviolet light
- Where
- 12 sites in Brazil
- Volunteers
- 5,000 people
- Sponsor
- Hospital Israelita Albert Einstein
Catheter Related Blood Stream Infections
Optimization of Therapeutic Drug Monitoring of Vancomycin in Pediatric Patients With an Implanted Port Catheter
The goal of this study is to verify whether extensive flushing of the port catheter in patients with catheter related blood stream infection will lead to correct vancomycin trough levels, taken via the port catheter and compared…
- Trial name
- NCT03720132
- Testing
- Extensive flushing of the port catheter
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Congenital Disorders
Chlorhexidine Swabs Effectiveness in Reducing Blood Stream Infections
Children's Healthcare of Atlanta (Children's) is collaborating with Child Health Corporation of America (CHCA) in the nationwide effort to reduce catheter related blood stream infections (BSIs).
- Trial name
- NCT00485992
- Where
- United States
- Volunteers
- 352 people
- Sponsor
- Children's Healthcare of Atlanta
Surgery, Central Line Associated Blood Stream Infections (CLABSI)
BIP CVC Clinical Safety and Performance Study
The primary objective of this trial was to determine Bactiguard coated BIP CVC's safety and performance and compare it to corresponding standard uncoated CVC.
- Trial name
- NCT02811380
- Testing
- BIP CVC, Uncoated Standard CVC
- Where
- Sweden
- Volunteers
- 36 people
- Sponsor
- Bactiguard AB