Clinical trials: Cavitated Caries
Dental Caries on Smooth Surface Limited to Enamel, Tooth Demineralization
Resin Infiltration and Fluoride Varnish Lesion Arresting Efficacy on Non-cavitated Proximal Lesion
Protection of dental hard tissues is one of the most important points of cariology. For this purpose, oral hygiene training (effective brushing and motivation), non-invasive approaches such as flouride varnish applications and…
- Conditions
- Dental Caries on Smooth Surface Limited to Enamel, Tooth Demineralization, Dental Caries, Dentistry, Operative
- Trial name
- NCT05202665
- Testing
- ICON DMG Resin Infiltration (micro-invasive approach), ClinproTM White Varnish, 3M ESPE Fluoride Varnish (non-invasive approach)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
Dental Caries
Development and Validation of a Multi-Mineral Fluoride Mouthrinse
The primary goals of this project are to determine the anticaries benefits of a prototype multi-mineral mouthrinse containing 225 ppm fluoride and 30 ppm of a Ca through the remineralization of enamel white-spots (non-cavitated…
- Trial name
- NCT00642252
- Testing
- Fluoride
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana Nanotech, LLC
Deep Caries, Pulp Exposure, Dental
Evaluation of Conservative Management of Teeth With Deep Cavitated Carious Lesions
The goal of this clinical trial is to compare postoperative pain of calcium silicate cement and resin-based tricalcium silicate (TheraCal LC) versus chemically Cured Glass Ionomer cement (FujiXI) in conservative management of…
- Trial name
- NCT06171776
- Testing
- RetroMTA, TheraCal, Fuji IX
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Fissure Sealant
Retention Rate and Caries Preventive Effect of Self Etch Giomer Based Fissure Sealant
With limited evidence-based information in literature about using giomer based pit and fissure sealant(BeautiSealant) in non-cavitated pits and fissures in permanent molars, it is beneficial to evaluate the newly introduced…
- Trial name
- NCT05336162
- Testing
- Self etch giomer based fissure sealant (BeautiSealant, Shoufu, USA)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Demineralization, Tooth, Demineralization, Fissure
Compariing a Bioactive Resin Material Used As A Fissure Sealant To A Conventional Resin
The aim of this study is to investigate the retention, marginal integrity and potential to prevent lesion progression of a bioactive resin material compared to a conventional resin-based flowable composite during management of…
- Conditions
- Demineralization, Tooth, Demineralization, Fissure, Non-Cavitated Caries
- Trial name
- NCT04052802
- Testing
- Fissure sealing
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries, Dental
Accuracy Of Sopro-Life Camera In Comparison With ICDAS II For Detection Of Initial Caries
This study will be conducted to assess diagnostic predictive values of a light induced fluorescence intraoral camera versus those of the visual-tactile assessment method according to modified ICDAS-II criteria in clinical
- Trial name
- NCT03586713
- Testing
- light induced fluorescence camera
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries Class II
Clinical Performance of Injection-Molding Vs. Incremental Packing of Resin Composite in Cavitated Posterior Teeth
The clinical performance of 2 bonding and composite packing techniques in the proximal cavities of permanent posterior teeth will be assessed.
- Trial name
- NCT05020093
- Testing
- Injection molding, Incremental packing
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Non-restorative Cavity Control in Anterior Cavitated Caries Lesion of Primary Teeth
Background: Studies have questioned the necessity of restoring cavitated carious lesion on primary teeth, once the control of biofilm is the most important factor to arrest these lesions.
- Trial name
- CEPECO2 (NCT03785730)
- Testing
- Non-restorative cavity control - NRCC group, Restoration with resin composite - RCR group
- Where
- Brazil
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Universidade Ibirapuera
Dental Caries, Dental White Spot
Effect of Light Curable Resin Modified Glass Ionomer Varnish on Non-Cavitated Proximal Carious Lesions' Progression
The standard-of-care preventive measures to stop early tooth decay from becoming worse is by fluoride application, diet counseling, and oral hygiene instructions. This standard way is not always successful.
- Trial name
- NCT03685058
- Testing
- Light curable resin modified glass ionomer varnish, standard-of-care preventive measures
- Where
- Saudi Arabia
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Initial Caries, Arrested Dental Caries
Early Caries Lesion Management Observational Study
The purpose of this observational study is to assess the effectiveness of Curodont Repair Fluoride Plus (CRFP) compared to other tooth-specific treatments (silver diamine fluoride (SDF), sealants, or other FDA-approved…
- Conditions
- Initial Caries, Arrested Dental Caries, Cavitated Caries, Dental Caries
- Trial name
- ELMO (NCT04933331)
- Testing
- Curodont Repair Fluoride Plus, Silver Diamine Fluoride, Glass Ionomer Sealant
- Where
- 4 sites in United States
- Volunteers
- 744 people, healthy volunteers welcome
- Sponsor
- CareQuest Institute for Oral Health
Proximal Caries
Effect of Self-Assembling Peptides on the Progression of Non-Cavitated Proximal Caries
The aim of this randomized controlled, double-blinded, split-mouth clinical trial was to evaluate the efficacy of self-assembling peptide P11-4 solution (Curodont™ Repair) with fluoride varnish on the progression of non-cavitated…
- Trial name
- NCT04776785
- Testing
- Curodont™ Repair, MI Varnish™, Profluorid® Varnish
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Dental Caries
Radiographic Contrast To Differentiate Cavitated From Non-cavitated Tooth Decay
The proposed test is intended to enable dentists to differentiate between cavitated and non-cavitated tooth decay in the areas where teeth are in contact (interproximal surfaces).
- Trial name
- NCT02359279
- Testing
- Sodium iodide
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Creighton University
Dental Caries
Use of Radiographic Contrast to Detect Dental Caries
The proposed test is intended to enable dentists to differentiate between cavitated and non-cavitated tooth decay in the areas where teeth are in contact (interproximal surfaces).
- Trial name
- NCT01523509
- Testing
- Radiographic contrast agent. Sodium Iodide.
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Creighton University