Clinical trials: Cavities
Nasal Cavity
Evaluation of Inter-patient Variability Size of the Nasal Cavity, Based on CT Scans
This study is part of the french research program ANR NEMRO "MICROROBOTIC NASAL ENDOSCOPY BY OPTICAL COHERENCE TOMOGRAPHY: IMPACT OF SMELL DEFICIENCY ON NEURODEGENERATIVE DISEASES." Recent studies have shown a strong correlation…
- Trial name
- NEMROfentes3D (NCT02879253)
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Caries, Dental
Clinical Performance of an Alkasite-based Restorative Material
The evolution of restorative dental materials and technology has enabled the use of tooth-colored restorative materials in dental restorations, with all dentists hoping for the presence of materials that combine biocompatible…
- Trial name
- NCT06317857
- Testing
- Centio Forte
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cairo University
Any Ear Nose or Throat Conditions, With Identified Need for a Diagnostic Procedure or Surgery on or Through the Mucous Membranes of the Nasal Cavities
Topical Application of Cocaine HCl 4%, or 10%, or Placebo Solution in Local (Topical) Anesthesia
Randomized, prospective, multi-center, double blind placebo-controlled parallel group study of a Placebo Topical Solution versus Cocaine HCl 4% Topical Solution for safety and efficacy, and Cocaine HCl 4% and 10% Topical Solution…
- Trial name
- NCT02500836
- Testing
- Cocaine HCl 4% Topical Solution, Cocaine HCl 10% Topical Solution
- Where
- United States
- Volunteers
- 646 people, healthy volunteers welcome
- Sponsor
- Lannett Company, Inc.
Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer
Immunohistochemical Expression of EGFR in the Patients Having Oral Squamous Cell Carcinoma
Oral squamous cell carcinoma (OSCC) is one of the top 10 most common malignancies worldwide. Oral squamous cell carcinoma forms a major health problem in many countries.
- Trial name
- EGFR (NCT06606301)
- Testing
- BioSB EGFR antibody
- Where
- Pakistan
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Combined Military Hospital, Pakistan
Apical Periodontitis, Pulp Disease, Dental
In Vivo-Ex Vivo Evaluation of the Root ZX3 for Working-Length Determination
This study evaluates the accuracy and repeatability of the Root ZX3 electronic apex locator for determining root canal working length in single-rooted permanent teeth requiring extraction.
- Trial name
- NCT07689838
- Testing
- Root ZX3 Electronic Apex Locator
- Where
- Saudi Arabia
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Dental Caries
Clinical Performance of a Highly-filled Flowable Composite in Class III Restorations.
The aim of this study was to evaluate the 12-month clinical performance of a highly filled flowable composite resin in anterior teeth.
- Trial name
- NCT07051551
- Testing
- tooth restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Carious Teeth
Clinical Evaluation of Different Bulk-fill Composite Restorations on Posterior Teeth
Different bulk-fill composites will be applied in different posterior cavities then compared
- Trial name
- 2-Year (NCT06226389)
- Testing
- Flowable bulk-fill resin composite, preheated bulk-fill resin composite, sonic bulk-fill resin composite
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Management of Dental Caries of Primary Molars
Clinical Performance of a Flowable Bulk Fill Composite Versus a Highly Viscous Glass-ionomer Cement in Primary Molars
the study was conducted to compare and evaluate the clinical performance of EQUIA Forte and SDR® flow+ in class II cavities in primary molar
- Trial name
- NCT06166160
- Testing
- Bulk fill flowable composite SDR Dentsply sirona
- Where
- 2 sites in Egypt
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Oropharyngeal Squamous Cell Carcinoma, Human Papillomavirus Infection
Saliva Testing for High-Risk Human Papillomavirus Infection Oral Cavity and Pharynx Cancer
The purpose of this research study is to determine if saliva and oral swab samples can be used to detect human papillomavirus in patients with cancer.
- Trial name
- NCT06362421
- Testing
- Pre-Radiation Dental Evaluation/Sample Collection, Pre-Study Visit, Oral Medicine Consultation Visit/Sample Collection
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Endometriosis of the Cul-de-sac, Chocolate Cyst of Ovary
Peritoneal Cavity Conditioning Decreases Pain, Inflammation and Adhesions
Full conditioning of the peritoneal cavity during laparoscopic surgery will decrease post-operative pain, inflammation and adhesion formation.
- Conditions
- Endometriosis of the Cul-de-sac, Chocolate Cyst of Ovary, Fibroid/Myoma (Uterus/Cervix)
- Trial name
- NCT01344486
- Testing
- full conditioning, standard pneumoperitoneum
- Where
- Belgium
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Knee Osteoarthritis
Treatment of Knee Osteoarthritis (KOA) by Injection of Autologous Adipose-derived Vascular Matrix Components (SVF) Into Joint Cavity
The purpose of this study was to analyze and study the efficacy and safety of autologous adipose-derived vascular matrix components (SVF) in patients with knee osteoarthritis before and after treatment through clinical…
- Trial name
- NCT06109220
- Testing
- Stromal vascular fraction,SVF
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Mineral Trioxide Aggregate, Calcium Hydroxide
Clinical Performance of MTA Cavity Lining in the Treatment of Deep Caries Lesions
Aim of this clinical study is to compare the clinical success of two lining materials regarding the maintenance of pulp vitality in the treatment of deep caries lesions over 4- years.
- Conditions
- Mineral Trioxide Aggregate, Calcium Hydroxide, Indirect Pulp Capping
- Trial name
- NCT04018716
- Testing
- MTA, Dycal
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Molar Incisor Hypomineralization, Dental Caries
Prevalence of MIH in Young Adults At Cairo University Dental Hospital and Its Link to Dental Cavities: a Cross-Sectional Study
We are conducting a study to understand how often MIH (Molar Incisor Hypomineralization) occurs and whether it is linked to a higher chance of dental cavities (caries).
- Trial name
- NCT06701552
- Where
- Egypt
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infertility, IVF
Effects of E2, P4 and LH Levels on the Day of Transfer and Endometrial Cavity Thickness on Implantation Success in Patients With Frozen-thawed Embryo Transfer Cycle
Thanks to recent advances in clinical practice and laboratory, embryo cryopreservation has become the first-line procedure in assisted reproductive technology.
- Conditions
- Infertility, IVF, Progesterone
- Trial name
- NCT04769401
- Testing
- Normal Progesterone group, Low Progesterone group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Pancreatic Cancer, Thyroid Cancer
Integrated Cancer Repository for Cancer Research
The iCaRe2 is a multi-institutional resource created and maintained by the Fred \& Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer…
- Conditions
- Pancreatic Cancer, Thyroid Cancer, Lung Cancer, Esophageal Cancer
- Trial name
- iCaRe2 (NCT02012699)
- Where
- 42 sites in United States
- Volunteers
- 999,999 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Head and Neck Cancer
Carcinologic Speech Severity Index
The hypothesis of the present study is that an automatic assessment technic can measure the impact of the speech disorders on the communication abilities giving a severity index of speech in patients treated for head and neck and…
- Trial name
- C2SI (NCT02875795)
- Testing
- automatic speech processing tool
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Tuberculosis
Phase III Clinical Study of Efficacy and Safety of Vaccae™ to Prevent Tuberculosis
Mycobacterium Vaccae for Injection (Trade Name "Vaccae") is a kind of bio-products developed by Anhui Zhifei Longcom Biopharmaceutical Co.,Ltd.,and got "The New Drug Certificate "in 1999.
- Trial name
- NCT01979900
- Testing
- Vaccae
- Where
- 4 sites in China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Dental Caries
Clinical Performance of Different Ion-Releasing Restorative Systems in Class II Cavities
Different ion-releasing restorative systems will be applied in class II cavities then their clinical performance will be evaluated and compared
- Trial name
- ION-REST II (NCT07688343)
- Testing
- conventional bulk fill restorative system, ion-releasing restorative system 1, ion-releasing restorative system 2
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Sensitivity, Tooth
Dentinal Hypersensitivity Reduction Efficacy Study
Assess the clinical efficacy of CSPR Toothpaste containing 8% arginine to provide dentinal hypersensitivity relief
- Trial name
- NCT06960148
- Testing
- CSPR Toothpaste, Colgate Dental Cream Toothpaste
- Where
- China
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Epistaxis, Intubation Complication
The Effect of Bevel Direction on the Pathway of the Nasotracheal Tube
In this study, the subjects are divided into two groups (group I: intervention group = the nasotracheal tube inserted with the bevel of the nasal tube facing the direction of the patient's head, and Group II: conventional group =…
- Trial name
- NCT03740620
- Testing
- Bevel facing the cephalad direction of the patient, Bevel facing leftward of the patient
- Where
- South Korea
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital