Clinical trials: Central Auditory Disease
Neuromyelitis Optica Spectrum Disorder
Acceptability and Safety of MR-C-014 in Persons With Neuromyelitis Optica Spectrum Disorder
The purpose of this proof of concept study is to assess the acceptability and safety of MR-C-014 in persons with Neuromyelitis optica spectrum disorder (NMOSD) who have a gait deficit.
- Trial name
- aNiMatO (NCT06374264)
- Testing
- MR-C-014
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- MedRhythms, Inc.
Sensorineural Hearing Loss, Presbyacusis
First In Human Randomised Trial of Rincell-1 in Adults With a Cochlear Implant
Rinri Therapeutics is conducting a clinical trial of a new cell therapy called Rincell-1. Rincell-1 is being developed to treat adults with neural hearing loss, either age related hearing loss or auditory neuropathy, who also…
- Conditions
- Sensorineural Hearing Loss, Presbyacusis, Auditory Neuropathy
- Trial name
- NCT07032038
- Testing
- Otic neural progenitors, cochlear implantation
- Where
- 3 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- Rinri Therapeutics
Tinnitus, Neuromodulation
Investigation to the Mechanism of the Neuroplastic Modulation in Central Auditory Tract
Tinnitus is the awareness of sound or noise in the absence of acoustic stimulation. No definite therapeutic strategy of tinnitus has been developed yet.
- Conditions
- Tinnitus, Neuromodulation, Electroacupuncture, Cochlear Diseases
- Trial name
- NCT05591807
- Testing
- Electroacupuncture
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Central Auditory Disease, Healthy
Testing a Possible Cause of Reduced Ability of Children to Process Speech in Noise
This study aims to increase our understanding of the difficulty people have recognizing the spoken word, especially in noisy situations.
- Trial name
- NCT00001957
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Parkinson Disease
Efficacy and Safety or Rhythmic Auditory Stimulation (RAS) for Gait and Balance Disorders in Parkinson's Disease
Gait deficits are among the most characteristic and most functionally debilitating signs of the motor neuropathology of Parkinson's disease (PD).
- Trial name
- ERA-EP2 (NCT03278639)
- Testing
- Rhythmic Auditory Stimulation, Kinesiology
- Sponsor
- Pontifical Catholic University of Argentina
Autism Spectrum Disorder (ASD), Central Auditory Processing Disorder
Mental And Speech Developmental Delay Autism Spectrum-Type Behavioral Disorder
FAMILY SYSTEM CITADEL 2060.METHODOLOGY "VOICE OF SLEEP MAMABEE 2026-2085 Systemic work with brain neurons through training modules at the border of sleep in clinical, psychological and strategic logic.
- Conditions
- Autism Spectrum Disorder (ASD), Central Auditory Processing Disorder, Nervous System Disorder, Neurological Disorder
- Trial name
- NCT07670000
- Testing
- Audio fairy tales
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Natalia Poluektova
Parkinson Disease
Freezing in Parkinson's Disease
The aim of this study was to investigate the effects of a visual and auditory cueing walker on freezing of gait during walking in patients with Parkinson\'s disease (PDF), compared to Parkinson patients without freezing of…
- Trial name
- parkinson (NCT07212205)
- Testing
- Visual & Auditory Cueing Walker
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Necmettin Erbakan University
Temporal Lobe Epilepsy
Closed Loop Auditory Stimulus in Sleep and epilepsY
This is a single-centre pilot study of a non-invasive auditory stimulation during sleep in participants with temporal lobe epilepsy.
- Trial name
- CLASSY (NCT05159609)
- Testing
- Closed loop auditory stimulus
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- Cardiff and Vale University Health Board
Alzheimer Disease (AD), Mild Cognitive Impairment (MCI)
Use of a Mobile Brain-Body Imaging Approach to Evaluate the Effects of Rhythmic Auditory Stimulation on Gait and Brain Function in Alzheimer's Disease
Alzheimer's Disease (AD) is associated with impairments in both gait and cognition, significantly increasing fall risk. Falls are a leading cause of injury-related disability in older adults, and individuals with AD experience a…
- Trial name
- NCT07659964
- Testing
- Metronome
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Stroke
Comparative Impact of RAST and TST for Improving Motor Functions in Stroke Patients
This study evaluates the effectiveness of Rhythmic Auditory Stimulation (RAS) therapy versus Task-Specific Training (TST) in enhancing motor function recovery in stroke patients.
- Trial name
- NCT06761638
- Testing
- Rhythmic Auditory Stimulation Therapy, Task-Specific Training
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Superior University
Generalized Anxiety Disorder
ERP N1 as a Treatment Predictor of Generalized Anxiety Disorder
Amplitude changes of the N1 and the N1/P2 ERP component in response to different tone intensities have been suggested as a correlative of central serotonergic activity.
- Trial name
- N1 (NCT00613067)
- Testing
- escitalopram
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Inje University
Traumatic Brain Injury, Coma
The Efficacy of Familiar Voice Stimulation During Coma Recovery
The purpose of the study is to determine whether familiar vocal stimulation, provided during coma recovery, improves outcomes for persons who are unconscious after severe TBI.
- Conditions
- Traumatic Brain Injury, Coma, Vegetative State, Minimally Conscious State
- Trial name
- FAST (NCT00557076)
- Testing
- Familiar Auditory Sensory Training
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- VA Office of Research and Development
Siderosis, Neurological Disorder
Audiovestibular Function in Infratentorial Superficial Siderosis
One in six people in the United Kingdom and over 400 million people worldwide have disabling hearing loss. This figure will double by 2050 as predicted by the World Health Organisation.
- Conditions
- Siderosis, Neurological Disorder, Rare Diseases, Age Related Hearing Loss
- Trial name
- AViSS (NCT04200664)
- Testing
- Hearing assessment, Vestibular/balance assessment, Quality of life assessment
- Where
- 2 sites in United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University College, London
Tinnitus, Epilepsy, Temporal Lobe
Pathophysiology, Psycho-emotional and Cognitive Functioning Associated With Tinnitus
the investigators have recently shown that patients with drug-resistant temporal lobe epilepsy who have undergone brain surgery targeting the medial temporal lobe structures were more likely to develop tinnitus postoperatively.
- Trial name
- AudiCog (NCT04717388)
- Testing
- acoustics tests, Questionaries,, MRI
- Where
- 2 sites in France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Parkinson's Disease
Proof of Concept BeatPark
Physical activity has demonstrated its beneficial effect on functional capabilities and quality of life in patients with PD. However, the daily physical activity remains limited in these patients.
- Trial name
- BEATPARK 2 (NCT02647242)
- Testing
- Auto rehabilitation program of gait with Beat Health device.
- Volunteers
- 45 people
- Sponsor
- University Hospital, Montpellier
Ischemic Stroke, Upper Extremity Paresis
Motor Task Performance Under Visual and Auditory Feedback Post Stroke: a Randomized Crossover Trial
The study was designed to evaluate the impact of a novel kinematic biofeedback system - SWORD - in the motor performance of patients after stroke.
- Trial name
- NCT03032692
- Testing
- SWORD, Exercise with biofeedback, exercise without biofeedback
- Where
- 3 sites in Portugal
- Volunteers
- 30 people
- Sponsor
- Sword Health, SA
Stroke, Old Age
Responders to Rhythmic Auditory Stimulation in Individuals Post-Stroke and Older Adults
Stroke is among the leading causes of long-term disability worldwide. Post-stroke neuromotor impairments are heterogeneous, yet often result in reduced walking ability characterized by slow, asymmetric, and unstable gait…
- Trial name
- NCT06085248
- Testing
- Subject-specific optimized RAS, Active walking
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Boston University Charles River Campus
Stroke, Perceptual Disorders
Dynamic Auditory Cueing for Spatial Neglect in Stroke
Spatial neglect is a common condition after stroke and can make it difficult for people to pay attention to one side of space. This problem can negatively affect daily activities and functional independence.
- Conditions
- Stroke, Perceptual Disorders, Spatial Neglect, Spatial Neglect After Stroke
- Trial name
- DAC-SN (NCT07507383)
- Testing
- Dynamic Auditory Cueing, Conventional Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Gazi University
Stroke
Effectiveness of WBV Versus RAS on Spasticity, Balance, and Lower Limb Motor Function on Hemiplegic Stroke Patients
This study investigates the effectiveness of whole-body vibration (WBV) versus rhythmic auditory stimulation (RAS) on spasticity, balance, and lower limb motor function in hemiplegic stroke patients.
- Trial name
- NCT06567223
- Testing
- Vibration Therapy, Rhythmic auditory stimulation therapy.
- Where
- 2 sites in Pakistan
- Volunteers
- 104 people
- Sponsor
- Superior University
Auditory Perceptual Disorder, Language Delay
Hereditary Deficits in Auditory Processing Leading to Language Impairment
Some children with certain language disorders may not properly process the sounds they hear, resulting in language impairments. The purpose of this study is to determine if deficits in auditory temporal processing the way the…
- Conditions
- Auditory Perceptual Disorder, Language Delay, Language Disorder
- Trial name
- NCT00004570
- Where
- United States
- Volunteers
- 875 people
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)