Clinical trials: Central Corneal Thickness
Corneal Edema, Corneal Endothelial Dysfunction
AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction
The purpose of this study is to assess the efficacy and safety of single injection dose of AURN001 compared with placebo in adult participants with corneal edema secondary to corneal endothelial dysfunction.
- Conditions
- Corneal Edema, Corneal Endothelial Dysfunction, Fuchs Endothelial Corneal Dysfunction, Pseudophakic Bullous Keratopathy (PBK)
- Trial name
- NCT07368959
- Testing
- Combination Product: AURN001 + Y-27632
- Where
- 12 sites in United States
- Volunteers
- 130 people
- Sponsor
- Aurion Biotech
Corneal Endothelial Cell Loss
Comparative Study of Specular Microscopes for Endothelial and Corneal Cell Measurements
The primary objective of this clinical study is to collect clinical data to support an FDA 510(k) submission for the Topcon Specular Microscope SP-1P.
- Trial name
- NCT02138266
- Testing
- Topcon Specular Microscope SP-1P, Konan Specular Microscope CELLCHEK XL
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Topcon Medical Systems, Inc.
Corneal Endothelial Cell Loss
Second Comparative Study of Specular Microscopes for Endothelial and Corneal Cell Measurements
The primary objective of this clinical study is to collect additional clinical data to support an FDA 510(k) submission for the Topcon Specular Microscope SP-1P.
- Trial name
- NCT02427256
- Testing
- Topcon Specular Microscope SP-1P, Konan Specular Microscope CELLCHEK XL
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Topcon Medical Systems, Inc.
Glaucoma Eye
Assessment of the Occuity PM1 Pachymeter
To determine whether the Occuity PM1 device is non-inferior in measuring central corneal thickness when compared to ultrasound pachymetry, the Lenstar and the Pentacam.
- Trial name
- NCT05895617
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Occuity Limited
Neurotrophic Keratitis, Neurotrophic Keratopathy
Open-label Trial to Evaluate Efficacy and Safety of rhNGF on Corneal Thickness Via AS-OCT in Neurotrophic Keratitis
Primary Objective: To assess the efficacy of cenegermin-bkbj (20 mcg/mL) ophthalmic solution on overall corneal thickness via AS-OCT in patients with stage 3 neurotrophic keratitis with respect to change from baseline at weeks 4…
- Conditions
- Neurotrophic Keratitis, Neurotrophic Keratopathy, Corneal Ulcer
- Trial name
- IMAGO (NCT06411145)
- Testing
- OXERVATE® 0.002%
- Sponsor
- Dompé Farmaceutici S.p.A
Glaucoma, Ocular Hypertension
Central Corneal Thickness With SENSIMED Triggerfish
Investigation of the occurrence of possible corneal swelling after continuous Intraocular pressure (IOP) monitoring with a contact lens-based Sensor during the sleeping period.
- Trial name
- 09/08 (NCT01210963)
- Testing
- SENSIMED Triggerfish
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Sensimed AG
Corneal and Endothelial Cell Measurements
Comparative Study of the TOMEY Specular Microscope EM-4000 and the Konan CellChek XL
The Tomey EM-4000 Specular Microscope is designed to observe and analyze corneal endothelium.
- Trial name
- NCT02977793
- Testing
- Tomey EM-4000 Specular Microscope, Konan CellChek XL Specular Microscope
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Tomey Corporation
Corneal and Endothelial Cell Measurements
Comparative Study of Specular Microscope for Cell Density, Coefficient of Variation, Hexagonality and Corneal Thickness
The primary objective of this clinical study is to collect clinical data to support an FDA 510(k) submission for the Nidek Specular Microscope CEM-530.
- Trial name
- NCT01729975
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.