Clinical trials: Central Line Catheters
PICC, Central Venous Catheter
Complications Associated With Central Venous Access in the NSICU: PICC vs CVC
The goal of this study is to determine whether Peripherally Inserted Central Catheter or Centrally Inserted Venous Catheters have lower complication rates in the Neuroscience Intensive Care Unit.
- Conditions
- PICC, Central Venous Catheter, Central Line, Neuro ICU
- Trial name
- NSPVC (NCT02314520)
- Testing
- peripherally inserted central catheter, centrally inserted central catheter
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Milton S. Hershey Medical Center
Catheter-related Bloodstream Infection
Expanded Access Program for Patients at Risk for Catheter-related Infections Who Are Not Eligible for DefenCath® Clinical Trials
The EAP for DefenCath is designed to provide access to a broader population of adult and pediatric patients using catheters for various serious medical conditions.
- Trial name
- NCT06707480
- Testing
- Taurolidine and Heparin
- Sponsor
- CorMedix Therapeutics
Nosocomial Infections, Bloodstream Infection
Surveillance for Nosocomial Infections in Pediatric Cancer Patients
The Oncoped 2006 study implements a multicenter prospective surveillance module for nosocomial infections in pediatric cancer patients.
- Conditions
- Nosocomial Infections, Bloodstream Infection, Invasive Aspergillosis
- Trial name
- Oncoped2006 (NCT00843804)
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bonn
Surgery, Multiorgan Failure
The Influence of Nursing Technique Applied at the Central Venous Catheter Insertion Site Upon the Incidence of Infection
Assessing the impact of the nursing technique applied at the insertion site of the central venous catheter using hydrophilic methacrylate gel (HMG) and 2% Chlorhexidine (CHG) upon the incidence of inflammatory complications when…
- Conditions
- Surgery, Multiorgan Failure, Haematologic Disease
- Trial name
- NCT03875352
- Testing
- CHG technique, HMG technique
- Where
- Czechia
- Volunteers
- 221 people
- Sponsor
- University Hospital Ostrava
Acute Anterior Myocardial Infarction
Rapid Intravascular Cooling in Myocardial Infarction as Adjunctive to Percutaneous Coronary Intervention
Rapid MI-ICE-Pilot is designed to demonstrate the safety and efficacy of the Celsius Control™ System (CCS) endovascular catheter to reduce the infarct size resulting from acute anterior myocardial infarction when used in…
- Trial name
- NCT00417638
- Testing
- Endovascular cooling by the Celsius Control System, Standard of care
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- ZOLL Circulation, Inc., USA
Central Venous Catheters, Ultrasound Guidance
Does the Needle-pilot Device Improve the Success of Vascular Catheterization Compared to the Classical Ultrasound-guided Technique
Real-time ultrasound guidance for central venous catheter catheterism is recommended in order to reduce complication, in particular for internal jugular site1.
- Trial name
- NEEDLE-VISIO (NCT04463147)
- Testing
- Needle-pilotTM device
- Where
- France
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Sickle Cell Disease, Central Venous Catheter Thrombosis
THromboprophylaxis In Sickle Cell Disease With Central Venous Catheters (THIS)
Research Question: In adult SCD patients with CVC, is it feasible and safe to conduct an adequately powered RCT to evaluate the use of rivaroxaban as thromboprophylaxis in this population? Study Design: The study is a vanguard…
- Conditions
- Sickle Cell Disease, Central Venous Catheter Thrombosis, Venous Thromboembolism
- Trial name
- THIS (NCT05033314)
- Testing
- Rivaroxaban 10 MG
- Where
- 3 sites in Canada
- Volunteers
- 4 people
- Sponsor
- University Health Network, Toronto
Central Venous Catheter Thrombosis, Central Venous Catheter Related Bloodstream Infection
CLiCK in the Critical Care Unit
Insertion of a central venous access device (CVAD) allows clinicians to easily access the circulation of a patient to administer life-saving interventions.
- Conditions
- Central Venous Catheter Thrombosis, Central Venous Catheter Related Bloodstream Infection, Catheter Complications, Catheter Blockage
- Trial name
- CLiCK (NCT04548713)
- Testing
- 4% EDTA, Saline
- Where
- 6 sites in Canada
- Volunteers
- 1,449 people
- Sponsor
- Fraser Health
Central Line, Central Venous Catheter
Statseal® for Central Venous Catheter Insertion Sites in Critical Care
All participants in this clinical trial will be undergoing surgery and will have a central venous catheter (also known as a central line) placed in the large vein in the neck as part of their routine care.
- Conditions
- Central Line, Central Venous Catheter, Vascular Access, Critical Care
- Trial name
- SCENIC (NCT06451185)
- Testing
- A haemostatic mineral powder product.
- Where
- United Kingdom
- Volunteers
- 451 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Diabetes Mellitus, Type 2, Catheterization, Peripheral
Incidence of Complications of Peripheral Venous Access in the Type 2 Diabetic Population
Diabetes Mellitus type 2 (T2DM) is one of the most frequent metabolic diseases worldwide. It is expected that in 2035 around 600 million people will suffer from the disease.
- Conditions
- Diabetes Mellitus, Type 2, Catheterization, Peripheral, Upper Extremity Deep Vein Thrombosis, Catheter-Related Infections
- Trial name
- NCT04499638
- Testing
- Peripheral vascular catheters
- Where
- Spain
- Volunteers
- 350 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Thrombosis, Venous
Venous Thrombosis After Removal of Central Venous Catheter
Insertion of intravenous catheter is a very common operation in patients in the general intensive care unit. These catheters are used for a variety of purposes - administration of inotropics/pressors, intravenous nutrition…
- Trial name
- NCT06349291
- Testing
- Detection of venous thrombosis via US
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
Catheter-Related Infections, Catheter Complications
Impact of Tubing Colonization on the Incidence of Central Venous Catheter Infection
The objective of this study is to assess the relationship between infusion system colonization (ramps or multi-lumen devices) and the occurrence of CVC infection/colonization.
- Conditions
- Catheter-Related Infections, Catheter Complications, Catheter Infection, Catheter-related Bloodstream Infection
- Trial name
- CRIC (NCT06019897)
- Volunteers
- 200 people
- Sponsor
- University Hospital, Angers
Cancer, Thrombosis
Efficacy & Safety of Prophylaxis With Bemiparin in Cancer Patients With a Central Venous Catheter (BECAT)
The purpose of this study is to evaluate the efficacy and safety of the subcutaneous administration for 45 days of Bemiparin (3,500 UI/day) in cancer patients with a CVC, to prevent CVC-related deep venous thrombosis (CVC-DVT)
- Trial name
- NCT00311896
- Testing
- Bemiparin
- Where
- 19 sites in Romania, Spain
- Volunteers
- 402 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Catheterization
Study of Chlorhexidine as the Hub Antiseptic to Prevent Catheter Related Infections in Newborn Infants
The purpose of this study is to prevent catheter-related infections in newborn infants admitted to the Neonatal Intensive Care Unit (NICU).
- Trial name
- NCT00516360
- Testing
- 3.15% chlorhexidine as daily antiseptic on needleless access port
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Trauma (Including Fractures), Dialysis Catheter
WALANT Versus Local Anesthesia in Central Venous Catheter Insertion
The goal of this clinical trial is to find out whether WALANT is an alternative local anesthesia method that can increase patient comfort and reduce pain during CVC procedure, which is one of the invasive procedures to be…
- Conditions
- Trauma (Including Fractures), Dialysis Catheter, Malnutrition Severe
- Trial name
- WALANT (NCT07299383)
- Testing
- local anesthesia with walant solution, Local anesthesia with lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Ataturk University
Central Venous Catheter, Coagulation
Contact Activation of Coagulation in Newly Inserted Central Venous Catheters
A central venous catheter (CVC) is a thin plastic tube placed into one of the body's large veins, typically in the neck or near the clavicle. CVCs are crucial for administering medications, fluids, and secure blood samples.
- Conditions
- Central Venous Catheter, Coagulation, Coagulation Activation, Central Venous Catheter Complications
- Trial name
- CAS-2 (NCT07014722)
- Testing
- MERITMEDICAL Careflow™ Two-Lumen Central Venous Catheter, ARROW Two-Lumen Central Venous Catheter, ARROWg+ard Blue Plus® Two-Lumen Central Venous Catheter
- Where
- Sweden
- Volunteers
- 88 people
- Sponsor
- Thomas Kander
Thromboses, Venous, Infection
Peripherally Inserted Versus Centrally Inserted Central Venous Catheters in the Neurosurgical Intensive Care Unit
This study aim to compare the cost-effectiveness and safety between centrally and peripherally inserted central venous catheters in neurosurgical intensive care unit patients.
- Conditions
- Thromboses, Venous, Infection, Economic Problems
- Trial name
- PICINI (NCT03908866)
- Testing
- PICC(Peripherally inserted central catheter), CVC(Central venous catheter )
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Critical Ill Patients, Central Venous Catheter
Development and Validation of an Ultrasound-Based Difficult Cannulation Risk Score
Ultrasound-guided internal jugular vein (IJV) catheterization is widely used in critically ill patients. Despite ultrasound guidance, difficult catheterization and first-pass failure remain clinically important and may increase…
- Trial name
- ROTATE-ICU (NCT07764562)
- Testing
- IJV Catheterization
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Antalya Health Sciences University