Clinical trials: Central Neck Dissection
Thyroid Cancer, Thyroid Carcinoma, Papillary
Near-infrared Fluorescence With Indocyanine Green for Identification of Sentinels and Parathyroids During Thyroidectomy
Indocyanine green (ICG) is a water-soluble organic dye that is cleared totally through the hepatobiliary system. It has a half-life of 3-4 mins, which allows repeated applications.
- Conditions
- Thyroid Cancer, Thyroid Carcinoma, Papillary, Thyroid Metastases, Thyroid Neoplasms
- Trial name
- NCT04424485
- Testing
- Total thyroidectomy (TT), Central lymph node dissection (CLND), Sentinel lymph node (SLN) bopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Umraniye Education and Research Hospital
Papillary Thyroid Carcinoma, Central Compartment Neck Dissction
The Role of Prophylactic Central Compartment Neck Dissection in the Management of 2 to 4 cm Papillary Thyroid Carcinoma
Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy and is frequently associated with microscopic central neck lymph node metastases, even in the absence of preoperative clinical evidence of nodal…
- Conditions
- Papillary Thyroid Carcinoma, Central Compartment Neck Dissction, Thyroidectomy, Thyroid Lobectomy
- Trial name
- PRO-COMAND (NCT06899347)
- Testing
- Total Thyroidectomy + Central Compartment Neck Dissection, Thyroid Lobectomy + ipCCND
- Volunteers
- 392 people
- Sponsor
- Leonardo Rossi
Hypocalcemia
Prevention of Hypocalcemia in Patients Undergoing Total Thyroidectomy Plus Central Neck Dissection
the increased risk of hypocalcemia following total thyroidectomy plus central neck dissection can be minimized by routine administration of oral calcium and vitamin D supplements during the early postoperative period.
- Trial name
- NCT00630214
- Testing
- Oral calcium plus vitamin D, Oral calcium alone
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Asan Medical Center
Papillary Thyroid Cancer
Papillary Thyroid Cancer and Central Lymp Node Dissection
Papillary cancer is a disease that spreads through lymphatic ways and its treatment is surgery. We performed prophylactic central dissection in addition to bilateral total thyroidectomy in patients with bethesda 5 and bethesda 6…
- Trial name
- NCT05873283
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Thyroid Cancer, Papillary
The Efficacy and Safety of Prophylactic Central Lymph Node Dissection in Papillary Thyroid Carcinoma
The aim of this study is to investigate the efficacy and safety of prophylactic central lymph node dissection in papillary thyroid carcinoma.
- Trial name
- NCT02418390
- Testing
- prophylactic central lymph node dissection
- Where
- South Korea
- Volunteers
- 101 people
- Sponsor
- Seoul National University Hospital
Head and Neck Squamous Cell Carcinoma (HNSCC)
Evaluation of Sentinel Lymph Nodes in Head and Neck Squamous Cell Carcinoma
The purpose of this study is to determine the false negative rate (FNR) associated with Lymphoseek-identified sentinel lymph nodes (SLNs) relative to the pathological status of non-sentinel lymph nodes in elective neck dissection…
- Trial name
- NCT00911326
- Testing
- Lymphoseek
- Where
- 13 sites in United States
- Volunteers
- 101 people
- Sponsor
- Navidea Biopharmaceuticals
Thyroidectomy, Thyroid Cancer
Evaluation of Central Compartment Dissection Without Thyroidectomy
In accordance with the current guidelines,papillary thyroid microcarcinoma such as turmo invasive nerve or trachea, requires total thyroidectomy for follow-up iodine-131 treatment.In the course of clinical work, if the patient…
- Conditions
- Thyroidectomy, Thyroid Cancer, Central Compartment Neck Dissction
- Trial name
- NCT03454464
- Testing
- Conventional, central neck dissection first
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fujian Medical University
Low-risk Papillary Thyroid Cancer, Endocrine Malignancy
Total Thyroidectomy With and Without Prophylactic Central Neck Lymph Node Dissection in People With Low-risk Papillary Thyroid Cancer
Background: Papillary thyroid cancer (PTC) often spreads to lymph nodes in the neck. This can be hard to detect. People often have lymph nodes removed anyway, and researchers want to study if this is a good idea.
- Conditions
- Low-risk Papillary Thyroid Cancer, Endocrine Malignancy, Thyroid Cancer
- Trial name
- NCT02408887
- Testing
- Total Thyroidectomy (TT), Prophylactic central neck lymph node dissection (pCND)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- National Cancer Institute (NCI)
Central Neck Dissection, Papillary Thyroid Carcinoma
Prophylactic Central Neck Dissection for Papillary Thyroid Carcinoma
This study designed to examine the utility of prophylactic central neck dissection (CND) in the management of papillary thyroid carcinoma (PTC), to assess the association between risk factors as gender, age at diagnosis, and size…
- Trial name
- NCT07911761
- Testing
- Thyroidectomy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Head and Neck Cancer
PET/CT Scan-Guided Watchful Waiting or Neck Dissection of Locally Advanced Lymph Node Metastases in Treating Patients Undergoing Chemotherapy and Radiation Therapy for Primary Head And Neck Cancer
RATIONALE: Imaging procedures, such as PET/CT scan, produce pictures of areas inside the body and may help doctors detect residual disease and plan the best treatment.
- Trial name
- NCT00720070
- Testing
- positron emission tomography/computed tomography, therapeutic conventional surgery
- Where
- United Kingdom
- Volunteers
- 560 people
- Sponsor
- Warwick Medical School
Papillary Thyroid Cancer
The Role of Central Neck Dissection in Stage N0 Papillary Thyroid Carcinoma
The benefits of prophylactic central neck dissection (pCND) remain controversial in clinically node-negative (cN0) papillary thyroid carcinoma (PTC).
- Trial name
- pCND (NCT04076514)
- Testing
- central neck dissection
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Vertebral Artery Dissection, Traumatic, Neck Pain
Effects of Spinal Manipulation on Vertebrobasilar and Internal Carotis Arteries in Healthy Population
After lumbar pain, neck pain is the most common cause of patients needing chiropractic care; the second most common cause of spinal manipulation use (1).
- Trial name
- NCT03435159
- Testing
- Doppler Ultrasonography, Manual Chiropractic Spinal Manipulation, Instrumental Chiropractic Spinal Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Thyroid Cancer
A New Surgical Strategy to Protect the Inferior Parathyroid
The incidence of temporary hypoparathyroidism after thyroid surgery is 14%-60%, and the incidence of permanent hypoparathyroidism is 4%-11%.
- Trial name
- NCT05758025
- Testing
- Resection based on "thymus-vascular-inferior parathyroid" complex
- Where
- China
- Volunteers
- 506 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Medullary Thyroid Cancer, Medullary Carcinoma
Is Desmoplastic Stromal Reaction Useful to Modulate Lymph Node Dissection in Sporadic Medullary Thyroid Carcinoma?
The oncologic benefit of lateral neck dissection (LND) during index operation for sporadic medullary thyroid carcinoma (MTC) basing on basal calcitonin (bCT) levels has been questioned due to the potential post-operative…
- Conditions
- Medullary Thyroid Cancer, Medullary Carcinoma, Medullary Tumor, Medullary Neoplasms
- Trial name
- DSR-MTC (NCT06243965)
- Where
- Italy
- Volunteers
- 246 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Thyroid Cancer, Recurrence
A Prospective, Open-label, Multicenter, Randomized Controlled Phase III Study of Prophylactic Central Neck Dissection in Low-risk Papillary Thyroid Cancer
papillary thyroid carcinoma (PTC) is the most common thyroid cancer and has a good prognosis. Surgery is the primary treatment for PTC, and occult lymph node metastasis is not uncommon (20%-80%).The lymph node metastasis of PTC…
- Trial name
- NCT06082180
- Testing
- prophylactic central neck dissection
- Where
- China
- Volunteers
- 1,199 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Papillary Thyroid Cancer
Prophylactic Central Neck Dissection for Papillary Thyroid Cancer
The purpose of this study is to determine whether prophylactic central neck dissection is beneficial for patients with papillary thyroid cancer staged preoperatively as node negative.
- Trial name
- NCT01510002
- Testing
- Total thyroidectomy, Total thyroidectomy + prophylactic central neck dissection
- Where
- Poland
- Volunteers
- 640 people
- Sponsor
- Jagiellonian University
Head and Neck Neoplasms
Definitive Chemo-Radiotherapy for Regionally Advanced Head and Neck Cancer With or Without Up-front Neck Dissection
Treatment of regionally-advanced head and neck squamous cell carcinoma (HNSCC) requires a multidisciplinary approach with a combination of surgery, radiotherapy (RT) and chemotherapy.
- Trial name
- UPFRONT-NECK (NCT02918955)
- Testing
- up-front neck dissection, radiotherapy, Chemotherapy (Cisplatin)
- Where
- 2 sites in Switzerland
- Volunteers
- 65 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hypopharyngeal Carcinoma
The Management of Metastatic Neck Nodes in N2/3 Hypopharyngeal Squamous Cell Carcinoma
This is a multi-center, multidisciplinary, open-label, randomized controlled prospective clinical study.
- Trial name
- NCT05494190
- Testing
- Docetaxel, Cisplatin, Capecitabine
- Where
- 3 sites in China
- Volunteers
- 111 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Thyroid Papillary Carcinoma
Prospective Study on the Clinical Prognosis of Bilateral Central Lymph Node Dissection in the Patients With Unilateral Thyroid Papillary Carcinoma
This study recruit the patients with unilateral papillary thyroid cancer before operation,the patients agree to enter the test,and divided into experimental and control group.experimental group patients receive the surgery…
- Trial name
- NCT02648399
- Testing
- surgery：BCND（bilateral central lymph node dissection）, surgery：UCND（unilateral central lymph node dissection）
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Fujian Medical University
Gastric Neoplasm, Esophageal Neoplasms
Non-curative ESDs: Assessing the Rates and Risk Factors for Residual Neoplasia
Short and long outcomes of ESD are well described, particularly in Eastern series. However, the outcome of non-curative ESDs is scarcely reported in the west (particularly among non-gastric or submucosal lesions).
- Conditions
- Gastric Neoplasm, Esophageal Neoplasms, Colorectal Neoplasms
- Trial name
- NC-ESD (NCT04484311)
- Where
- Portugal
- Volunteers
- 300 people
- Sponsor
- Universidade do Porto