Clinical trials: Central Post Stroke Pain
Hemiplegia, Stroke
The Effect of Shoulder Problems on Balance in Hemiplegic Patients
Shoulder problems are among the most common complications in hemiplegic patients and may impair shoulder biomechanics, negatively affecting mobility, transfers, and self-care.
- Trial name
- NCT07159178
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul Aydın University
Stroke, Rehabilitation
The Kinesio-taping for the Prevention of Painful Shoulder and for the Functional Recovery of Upper Limb After Stroke
This RCT aims to investigate the effectiveness of the early use of Kinesio-taping (KT) together with standard physiotherapy treatment, in the prevention of the shoulder pain of the hemiplegic upper limb following a cerebral…
- Trial name
- NCT05156164
- Testing
- Kinesio Tape Group, Control Group
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Stroke, Complex Regional Pain Syndrome I (CRPS I)
Mirror Therapy for Complex Regional Pain Syndrome in Stroke Patients
The goal of this clinical study is to evaluate the effectiveness of mirror therapy in treating complex regional pain syndrome (CRPS) in patients after stroke using clinical assessments, electrophysiological evaluations, and…
- Conditions
- Stroke, Complex Regional Pain Syndrome I (CRPS I), Mirror Therapy
- Trial name
- MT-CRPS-ST (NCT07537465)
- Testing
- Mirror Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Central Post Stroke Pain
Efficacy of Pain Intervention With Deep Brain Stimulation Neuromodulation
The goal of this clinical trial is to learn if deep brain stimulation (DBS) works to treat severe pain following a stroke in adults. It will also learn about the safety of deep brain stimulation.
- Trial name
- EPIONE (NCT06387914)
- Testing
- Stimulation ON, Stimulation Pseudo-ON
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Oxford
Stroke
A Study of Post-Stroke Pain and Fatigue: Clinical Evaluation and Treatment Effect
The investigators anticipate this research will shed light on metric properties of outcome measures of pain and fatigue and the effects of the combined therapy for stroke patients.
- Trial name
- NCT01913509
- Testing
- Combined Therapy of FES and BAT, Conventional Rehabilitation
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- Chang Gung University
Chronic Neuropathic Pain, Post-Stroke Pain
Transcranial Magnetic Stimulation for Chronic Neuropathic Pain
Chronic neuropathic pain is defined as pain caused by a lesion or disease of the somatosensory nervous system. It is highly prevalent, debilitating, and challenging to treat.
- Conditions
- Chronic Neuropathic Pain, Post-Stroke Pain, Trigeminal Neuralgia, Nerve Injury
- Trial name
- NCT05593237
- Testing
- High Frequency rTMS, Low Frequency rTMS
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, San Francisco
Spinal Cord Diseases, Spinal Cord Injuries
An Open-Label Long-Term Study Of Pregabalin For The Treatment Of Central Neuropathic Pain
The purpose of this study is to assess the safety of the long-term use of pregabalin at doses up to 600 mg/day in patients with central neuropathic pain (post spinal cord injury pain, post stroke pain, and multiple sclerosis…
- Conditions
- Spinal Cord Diseases, Spinal Cord Injuries, Neuralgia, Pain
- Trial name
- NCT01202227
- Testing
- pregabalin
- Where
- 26 sites in Japan
- Volunteers
- 104 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Stroke
Myofascial Dysfunction in Post Stroke Shoulder Pain
Shoulder pain is extremely common after stroke and occurs in 30-70% of patients. The pain may begin as early as one week after stroke, although peak onset and severity occurs around four months, and persists into the chronic…
- Trial name
- NCT06718413
- Testing
- hyaluronidase plus saline, saline
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Johns Hopkins University
Post-stroke Spasticity
Pain During Injection With Botulinum Toxin in Post-stroke Spasticity Treatment
The aim of the study was to analyze which step of the procedure of toxin botulinum injection is the most painful between skin break-in, electric stimulation, injection and needle withdrawal.
- Trial name
- DOLOTOX (NCT03251521)
- Testing
- pain rating during injection with botulinum toxin
- Volunteers
- 46 people
- Sponsor
- University Hospital, Grenoble
Chronic Pain, Post Stroke Pain
Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pain
Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but current technology is unable to reliably achieve long-term pain symptom relief.
- Conditions
- Chronic Pain, Post Stroke Pain, Phantom Limb Pain, Spinal Cord Injuries
- Trial name
- NCT03029884
- Testing
- Open-Loop DBS, Closed-Loop DBS
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Prasad Shirvalkar, MD, PhD
Stroke
The Effect of Electrical Stimulation on Impairment of the Painful Post-Stroke Shoulder
Examination of the effects of short-term use of TENS and t-NMES on passive pain-free ROM of the painful post-stroke shoulder. Treatments are compared with no stimulation.
- Trial name
- NCT03683901
- Testing
- TENS, t-NMES, No stimulation
- Volunteers
- 10 people
- Sponsor
- MetroHealth Medical Center
Stroke, Shoulder Pain
Effects of Low Frequency TENS and Therapeutic Ultrasound in Post-stroke Shoulder Pain
Brief Summary: Post-Stroke shoulder pain is a well-known complication and is responsible for the reduction in functional outcomes.
- Trial name
- NCT05931185
- Testing
- low frequency transcutaneous electrical stimulation and Therapeutic Ultrasound, Therapeutic Ultrasound, Low frequency transcutaneous electrical stimulation
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Central Post Stroke Pain
Efficacy of Transcranial Magnetic Stimulation (TMS) in Central Post Stroke Pain ( CPSP)
The aim of the study is to evaluate the analgesic effects of navigated repetitive transcranial magnetic stimulation in central post stroke pain. MRI based navigation is used to determine the exact locations for stimulation.
- Trial name
- NCT02277912
- Testing
- navigated rTMS of motor cortex, navigated rTMS of somatosensory cortex 2
- Volunteers
- 21 people
- Sponsor
- Helsinki University Central Hospital
Chronic Pain, Stroke
VR-ACT After Stroke: a Feasibility Study
This exploratory project aims to develop and pilot test, in a parallel group randomized controlled trial (RCT) design, the feasibility, acceptability, and preliminary efficacy of a self-management virtual reality (VR) 8-week…
- Trial name
- VR-ACT (NCT06990646)
- Testing
- VR-ACT
- Volunteers
- 30 people
- Sponsor
- University of Coimbra
Shoulder Pain Chronic
An Implantable Microneuromodulator for the Treatment of Chronic Shoulder Pain in Chronic Post-Stroke Subjects
The goal of this research study is to investigate safety and gather initial effectiveness data for a new implanted device designed to treat chronic shoulder pain in chronic post-stroke subjects.
- Trial name
- BBPM (NCT00567541)
- Testing
- Battery Powered Microneuromodulator (BBPM)
- Where
- 3 sites in United States
- Volunteers
- 16 people
- Sponsor
- Bioness Inc
Pain, Chronic
Effectiveness and Safety of tDCS for Pain
The purpose of this study is to verify the effectiveness and safety of transcranial direct current stimulation in patients with central post-stroke pain.
- Trial name
- NCT05612165
- Testing
- Transcranial Direct Current Stimulation(tDCS)
- Where
- South Korea
- Volunteers
- 23 people
- Sponsor
- Pusan National University Yangsan Hospital
Stroke
Dry Needling for Shoulder Pain in Stroke Patients
Spasticity and pain, particularly int he shoulder region, are the most common impairments experienced by subjects who had experienced a stroke.
- Trial name
- NCT03703193
- Testing
- Dry Needling, Physical Therapy
- Where
- Spain
- Volunteers
- 16 people
- Sponsor
- Universidad Rey Juan Carlos
Intracerebral Hemorrhage, Hemorrhagic Stroke
Outcome Prediction and Recovery After Spontaneous Intracerebral Haemorrhage
Spontaneous intracerebral haemorrhage (ICH) is a severe form of stroke with high mortality and frequent long-term disability. Current tools to predict how an individual patient will recover are limited.
- Trial name
- CR-4-Health (NCT07882784)
- Where
- 3 sites in Austria, Slovenia
- Volunteers
- 300 people
- Sponsor
- University Medical Centre Maribor
Cerebrovascular Disorders, Spasticity, Muscle
The Effect of Ultrasound-Guided Botulinum Toxin Injections on Pain, Functionality, Spasticity, and Range of Motion in Patients With Post-Stroke Upper Extremity Spasticity
The patients between the ages of 35-80 who developed spasticity in the upper extremity after stroke will be included.. Botulinum toxin(BT-A) injection will be applied to the study group(n=16) and placebo injection to the control…
- Conditions
- Cerebrovascular Disorders, Spasticity, Muscle, Botulinum Toxin
- Trial name
- NCT05887479
- Testing
- Botulinum toxin type A, %0,9 NaCl
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Stroke
ROBOtic Care of Post-stroke Pain.
In agreement to the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) recommendations that support the importance of physical functioning as core outcome for pain this randomized, double-blind…
- Trial name
- Robocop (NCT05288270)
- Testing
- Aramis, Conventional therapy
- Volunteers
- 118 people
- Sponsor
- S.Anna Rehabilitation Institute