Clinical trials: Central Sleep Apnea
Alzheimer Disease, Sleep Apnea
Sleep Aging and Risk for Alzheimer's 2.0
Age-related sleep changes and common sleep disorders like obstructive sleep apnea (OSA) may increase amyloid burden and represent risk factors for cognitive decline in the elderly.
- Trial name
- SARA (NCT03278119)
- Testing
- PET Scan and nocturnal polysomnography
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Central Sleep Apnea, ASV
Interface Selection for Adaptive Servo Ventilation
The purpose of this study is to compare the effects of nasal and oronasal interfaces during ASV treatment on sleep efficiency and sleep architecture.
- Trial name
- NCT02919930
- Testing
- Switch from oronasal to nasal mask during ASV treatment, Switch from nasal to oronasal mask during ASV treatment
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Stroke
Stroke - Sleep Disorders, Dysfunction of the Autonomic Nervous System and Depression
The purpose of this study is to investigate sleep disordered breathing, autonomic dysfunction, and post stroke depression in acute and chronic stroke patients.
- Trial name
- NCT02111408
- Where
- Denmark
- Volunteers
- 114 people
- Sponsor
- Helle Klingenberg Iversen, MD, DmSc
Sleep Apnea Syndromes, Insomnia Disorder
Apnea and Insomnia Relief Study
The purpose of this study is to determine whether a behavioral sleep treatment improves functioning and sleep in Veterans with posttraumatic stress disorder (PTSD).
- Conditions
- Sleep Apnea Syndromes, Insomnia Disorder, Stress Disorders, Post-Traumatic
- Trial name
- AIR (NCT04007796)
- Testing
- Apnea and Insomnia Relief (AIR), Sleep Education (SE)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Obstructive Sleep Apnea
Transcutaneous Electrical Stimulation in Patients With Obstructive Sleep Apnoea
The objective of this trial is to assess efficacy and compliance of transcutaneous electrical stimulation of the upper airway dilator muscles in patients with obstructive sleep apnoea (TESLA) who do not tolerate continuous…
- Trial name
- TESLA-MICRON (NCT07343362)
- Testing
- ZeusOSA, CPAP
- Volunteers
- 186 people
- Sponsor
- Zeus Sleep Ltd
Sleep Disordered Breathing (SDB), Sleep Apnea
Sleep Disordered Breathing and Multimorbidity: The Xiangya SDB Cohort Study
Sleep disordered breathing (SDB) is one of the most common sleep disorders, including obstructive sleep apnea (OSA), central sleep apnea (CSA), sleep-related hypoventilation, hypoxemia, etc., with OSA being the most prevalent.
- Conditions
- Sleep Disordered Breathing (SDB), Sleep Apnea, Cardiometabolic Diseases, Multimorbidity
- Trial name
- NCT06755840
- Where
- China
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Obstructive Sleep Apnea
Treatment of Obstructive Sleep Apnea (OSA) With the da Vinci® SP™ Surgical System
It is a prospective, single center, single-arm clinical study to enroll a maximum of 25 subjects.
- Trial name
- NCT04795817
- Testing
- Transoral Robotic Surgery
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Intuitive Surgical
Sleep Disordered Breathing
Opioid Safety Program in Pain Clinics (Op-Safe):
In this vital study, the investigators will develop an innovative Opioid Safety (Op-Safe) Program for use in pain clinics. The Op-Safe Program consists of two key components: Educating patients with an informative brochure and…
- Trial name
- NCT02513836
- Testing
- Pre-education intervention, Post-education intervention
- Where
- 5 sites in Canada
- Volunteers
- 304 people
- Sponsor
- University Health Network, Toronto
Retinal Vein Occlusion, Obstructive Sleep Apnea
Retinal Vein Occlusion and Obstructive Sleep Apnea: A Case Control Study
This study purpose is to evaluate the association between Retinal Vein Occlusion and Obstructive Sleep Apnea.
- Trial name
- SASOVR (NCT04011358)
- Testing
- Sleeping Monitor
- Where
- France
- Sponsor
- Centre Hospitalier Régional d'Orléans
Epilepsy, Obstructive Sleep Apnea
Investigation of Sleep Quality and Prevalence of Sleep-disordered Breathing in Children and Young People With Epilepsy
Obstructive sleep apnoea (OSA) is a condition that affects around one in 20 children. In children with OSA, repeated episodes of airway obstruction can severely disturb and fragment sleep, leading to subsequent cognitive and…
- Trial name
- NCT03103841
- Testing
- Sleep studies [Polysomnography]
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- NHS Lothian
Sleep Apnea
Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep Apnea
The primary purpose of this study is to evaluate the effectiveness of sivopixant, acetazolamide and SASS-001 in adults with sleep apnea with a central component.
- Trial name
- NCT06776432
- Testing
- Sivopixant, Acetazolamide, SASS-001
- Where
- 9 sites in United States
- Volunteers
- 60 people
- Sponsor
- Shionogi
Sleep Apnea, Obstructive
The Effects of CPAP Withdrawal on Cerebral Vascular Reactivity and Brain Oxygenation in OSA
Obstructive sleep apnoea (OSA) is a highly prevalent sleep-related breathing disorder associated with adverse cardiovascular outcome. Underlying mechanisms are subject of debate.
- Trial name
- NCT02493673
- Testing
- Continuous positive airway pressure device
- Where
- Switzerland
- Volunteers
- 49 people
- Sponsor
- University of Zurich
Ischemic Stroke, Sleep Apnea
Sleep for Stroke Management and Recovery Trial
The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke (1) reduces recurrent stroke, acute coronary syndrome, and…
- Conditions
- Ischemic Stroke, Sleep Apnea, Sleep Apnea, Obstructive, Stroke
- Trial name
- Sleep SMART (NCT03812653)
- Testing
- CPAP
- Where
- 116 sites in United States
- Volunteers
- 3,062 people
- Sponsor
- University of Michigan
Sleep Apnea Syndromes
Cloud Based Follow up of CPAP Treatment
Obstructive sleep apnea (OSA) is treated with a continuous positive airway pressure, so called CPAP. A new technology that enables telemetric monitoring of CPAP therapy.
- Trial name
- NCT03446560
- Testing
- CPAP, conventional follow up, CPAP, telemedicine based follow up
- Where
- Sweden
- Volunteers
- 403 people
- Sponsor
- Vastra Gotaland Region
Obstructive Sleep Apnea
Optimizing Treatment Effects on OSA-related Clinical and Patient-centered Outcomes Among Blacks
The study is to maximize efficacy of message delivery to achieve desired Obstructive sleep apnea (OSA) adherence goal. Newly diagnosed black patients (n=390, all genders) from participating sleep clinics will be randomly exposed…
- Trial name
- NCT03354520
- Testing
- Tailored Videos, OSA Treatment, Standard Videos
- Where
- United States
- Sponsor
- NYU Langone Health
Obstructive Sleep Apnea Risk Management, Postoperative Complications
OSA Risk Level in Dental Patients and Correlation With Complications After General Anesthesia
Obstructive sleep apnea (OSA) is a sleep-related respiratory dysfunction. The prevalence of OSA is increasing with the increasing rates of obesity and elderly population worldwide.
- Conditions
- Obstructive Sleep Apnea Risk Management, Postoperative Complications, Dental Caries Under General Anesthesia, Obstructive Sleep Apnea of Adult
- Trial name
- NCT06430957
- Testing
- The STOP-BANG questionnaire for determining OSA risk level., ASA recommended criteria for determining OSA risk level., Record of postoperative complications
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Kırıkkale University
Sleep Apnea, Obstructive, Sleep Apnea, Central
Sparkle Respiratory Effort Validation
This study has been developed in order to demonstrate the validity of the Sparkle respiratory effort signal.
- Trial name
- NCT04630639
- Testing
- Sparkle
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Sleep Apnea, Obstructive, Stroke
Stroke and CPAP Outcome Study 2
Obstructive sleep apnea (OSA) is associated with impaired stroke recovery. Treatment with continuous positive airway pressure (CPAP) may prevent this but is limited by poor adherence.
- Conditions
- Sleep Apnea, Obstructive, Stroke, Patient Adherence
- Trial name
- SCOUTS2 (NCT02809430)
- Testing
- Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Washington
Heart Failure, Central Sleep Apnea
Cardiac Resynchronisation Therapy in Combination With Overdrive Pacing in the Treatment of Central Sleep Apnea in CHF
The primary objective of this study is to compare the Apnea- Hypopnea Index in HF patients with concomitant CSA, after 12 weeks of CRT alone to CRT in combination with one night of overdrive pacing.
- Trial name
- Morpheus (NCT00551499)
- Testing
- CRT + AOP
- Where
- 2 sites in Germany
- Volunteers
- 44 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Hypertension, Chronic Kidneys Disease
Nocturnal Blood Pressure and Hypertension - Central and Peripheral 24-h Blood Pressure.
A new study have shown that high night time blood pressure (BP) and/or non-dipping (lack of fall in BP during night time) is a strong predictor for the risk of cardiovascular disease and mortality in patients with hypertension.
- Conditions
- Hypertension, Chronic Kidneys Disease, Obstructive Sleep Apnea
- Trial name
- HOSA (NCT02078765)
- Where
- Denmark
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Erling Bjerregaard Pedersen