Clinical trials: Central Spinal Cord Syndrome
Spinal Cord Injuries, Gait Disorders, Neurologic
Safety and Feasibility of TWIICE Rise - Phase 2
The aim of this study is to assess the safety and the feasibility of two versions of TWIICE Rise for exoskeleton-assisted ambulation in patients with a spinal cord injury.
- Trial name
- NCT07461259
- Testing
- TWIICE Rise
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- TWIICE
Spinal Cord Injury, Stroke
Veteran-Centered Outcomes Using Qualitative and Quantitative Methods
The purpose of this study is to modify and develop measures that reflect outcomes that are relevant to recovering Veterans and are sensitive to improvements resulting from innovative gait interventions.
- Trial name
- NCT00333580
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- US Department of Veterans Affairs
Spinal Cord Injuries
Combination Therapy to Improve SCI Recovery.
The purpose of this study is to determine how combining bouts of low oxygen, transcutaneous spinal cord stimulation, and walking training may improve walking function for people with chronic spinal cord injury.
- Trial name
- BO2ST (NCT05563103)
- Testing
- Daily acute intermittent hypoxia, Walking + tSTIM
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Spaulding Rehabilitation Hospital
Spinal Cord Injury
Robotic Gait Training VS.Conventional Rehabilitation in SCI
Until now, there's still no any strong evidence supported "which is the best way to restoration walking ability" in spinal cord injury.
- Trial name
- NCT01432990
- Testing
- Robot gait training, control
- Where
- Thailand
- Volunteers
- 16 people
- Sponsor
- Prasat Neurological Institute
Spinal Cord Injuries
Acute Effects of Continuous Verses Interval Aerobic Training in Spinal Cord Injury Patient
To determine the Acute effects of continuous verses interval aerobic training on autonomic dysreflexia in Spinal Cord injury Patient. To Determine the Acute effects of these training on, Exercise Self efficacy and pain.
- Trial name
- NCT05061160
- Testing
- Interval Aerobic Exercise training Group, Continuous Aerobic Exercise training Group
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Spinal Cord Injuries, Obesity
Building an Evidence Base for Weight Loss Strategies Among Those With Chronic SCI-The GLB-SCI+
This study's overarching aim is to follow a systematic approach that incorporates community-based participatory research (CBPR) to develop a multi-component weight loss intervention that may yield significant effects for a…
- Conditions
- Spinal Cord Injuries, Obesity, Weight Loss, Diet Modification
- Trial name
- GLB-SCI+ (NCT03874988)
- Testing
- Portion-Controlled Meals, Enhanced Self-Monitoring, GLB-SCI
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Spinal Cord Compression, Mucopolysaccharidosis I
Extension Study of Intrathecal Enzyme Replacement Therapy for MPS I
This is a one-year extension study of the use of laronidase into the spinal fluid to treat spinal cord compression in mucopolysaccharidosis I.
- Conditions
- Spinal Cord Compression, Mucopolysaccharidosis I, Hurler-Scheie Syndrome, Scheie Syndrome
- Trial name
- NCT00786968
- Testing
- laronidase
- Where
- 2 sites in United States, Finland
- Volunteers
- 3 people
- Sponsor
- Patricia I. Dickson, M.D.
Spinal Cord Injury
Magnetic Resonance Imaging of Cognitive Deficits in the Brain of Individuals With Spinal Cord Injury
In the case of spinal cord injury, rehabilitation is particularly focused on motor skills. Non-motor impairments such as thinking difficulties did not receive a lot of attention to date.
- Trial name
- SCI_Cog (NCT06309888)
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Spinal Cord Injury
Coronary Computed Tomography (CT) to Measure Coronary Calcification in Spinal Cord Injury (SCI)
Although conventional risk factors for coronary heart disease (CHD) have been identified and routinely used to determine risk for CHD in the general population, a systematic approach to determine population-specific risk for CHD…
- Trial name
- NCT01065896
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- US Department of Veterans Affairs
Spinal Cord Injuries
Duroplasty for Injured Cervical Spinal Cord With Uncontrolled Swelling
QUESTION. Does duroplasty improve outcome after spinal cord injury? WHAT DO WE STUDY? We will investigate whether performing a surgical procedure called duroplasty improves outcomes after spinal cord injury.
- Trial name
- DISCUS (NCT04936620)
- Testing
- Duroplasty, Spinal surgery
- Where
- 34 sites in Austria, Belgium and 10 more
- Volunteers
- 222 people
- Sponsor
- St George's, University of London
Spinal Cord Injuries
A Multicenter, Randomized, Double-blind, Placebo-controlled Phase 3 Study to Evaluate the Safety and Efficacy of ES135 in Subjects With Spinal Cord Injury
To demonstrate the superior effect of ES135 combined with spinal cord repairing surgery, compared to a placebo control with spinal cord repairing surgery, on post-surgery motor function recovery as measured by the changes from…
- Trial name
- NCT03229031
- Testing
- ES135
- Where
- 3 sites in Taiwan
- Volunteers
- 160 people
- Sponsor
- Eusol Biotech Co., Ltd.
Spinal Cord Injuries
Study on Preliminary Safety and Efficacy of the ARC Therapy Using the ARC-IM Lumbar System to Support Mobility in People With Chronic Spinal Cord Injury (BoxSwitch)
The purpose of this pre-market clinical study is to assess the preliminary safety and efficacy of the ARC Therapy using the ARC-IM Lumbar System at supporting mobility in participants who have previously received a spinal array…
- Trial name
- BoxSwitch (NCT05942339)
- Testing
- Procedure/Surgery
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- Ecole Polytechnique Fédérale de Lausanne
Spinal Cord Injury
Evaluation of Autologous Mesenchymal Stem Cell Transplantation in Chronic Spinal Cord Injury: a Pilot Study
The purpose of this study is to analyze the safety and efficacy of mesenchymal stem cell transplantation through percutaneous injection in patients with chronic spinal cord injury.
- Trial name
- NCT02152657
- Testing
- Mesenchymal stem cell transplantation
- Where
- Brazil
- Volunteers
- 5 people
- Sponsor
- Hospital Sao Rafael
Spinal Cord Injury
Integrated Tele-exercise for Individuals With Spinal Cord Injury
The objective of this study is to examine the efficacy of an integrated, participant-centered tele-health physical activity program for individuals with SCI on psychological and social factors through a parallel mixed-methods…
- Trial name
- NCT05360719
- Testing
- Group tele-exercise
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Drexel University
Spinal Cord Injuries
Intermittent Hypoxia and Upper Extremity EMG Recordings in Individuals With Spinal Cord Injury
In this current study, the examiners examine some of the mechanisms of how Acute Intermittent Hypoxia (AIH) effects the upper extremity of survivors of spinal cord injury.
- Trial name
- NCT05513911
- Testing
- Acute Intermittent Hypoxia
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries, Traditional Chinese Medicine
Effect of Acupressure on Constipation in Community-dwelling Spinal Cord Injury Patients: a Randomized Controlled Trial
Spinal cord injury is a multi-sensory, motor and autonomic dysfunction, caused by various types of acute and chronic central nervous system injuries. And it will affect patient's ability to live normally and return to society.
- Trial name
- NCT05558657
- Testing
- Home-based, acupressure combined with nursing education, Home-based, manual light touch of the abdomen combined with nursing education
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- The Hong Kong Polytechnic University
Spinal Cord Injuries
Association Between tDCS and Lokomat Training in Patients With Incomplete Spinal Cord Injury
The spinal cord injury is identified as the major cause of permanent disability worldwide, with the loss of ability to walk being the largest and most devastating of them for these patients.
- Trial name
- NCT02562001
- Testing
- Outpatient active group, Inpatient active group
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- University of Sao Paulo General Hospital
Tetraplegia, Tetraplegia/Tetraparesis
[BrainConnexion] - Neurodevice Phase I Trial
This study aims to evaluate the safety of a wireless implantable neurodevice microsystem in tetraplegic patients, as well as the efficacy of the electrodes for long-term recording of neural activities and the successful control…
- Conditions
- Tetraplegia, Tetraplegia/Tetraparesis, Spinal Cord Injuries, Amyotrophic Lateral Sclerosis
- Trial name
- NCT03811301
- Testing
- BrainConnexion
- Where
- Singapore
- Volunteers
- 5 people
- Sponsor
- National Neuroscience Institute
Pressure Ulcers, Spinal Cord Injury
BIONs, for Improved Tissue Health and Pressure Sore Prevention
The purpose of this study was to determine the feasibility of an implanted electrical stimulation system incorporating BION microstimulators for long term use to prevent tissue breakdown in high risk patients.
- Trial name
- NCT00262457
- Testing
- Implanted gluteal electrical stimulation system
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
SCI - Spinal Cord Injury
TPAD for Recovery of Standing After Severe SCI
The purpose of this study is to investigate how standing and sitting balance control is altered after spinal cord injury (SCI) and how a new type of robotic assistive device may be used to improve muscle function.
- Trial name
- NCT06643312
- Testing
- The Tethered Pelvic Assist Device (TPAD)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
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