Clinical trials: Central Spinal Cord Syndrome
Injuries, Spinal Cord
Diaphragm Pacing After Spinal Cord Injury
Respiratory dysfunction is the leading cause of death in individuals with spinal cord injuries (SCIs). Nearly one quarter of all SCI cases involve injury to the upper spinal cord segments which impairs neural activation of the…
- Trial name
- NCT02556125
- Testing
- Diaphragm pacing
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- University of Florida
Spinal Cord Injury Thoracic
Electromyography-Triggered Electrical Stimulation on Trunk Balance and Muscle Thickness in SCI Patients
The aim of this study was to investigate the effect of electromyography (EMG) triggered electrical stimulation (ES) applied to multifidus and erector spinae muscles on trunk balance in patients with complete thoracic spinal cord…
- Trial name
- NCT06527417
- Testing
- Neuro Trac Myo Plus Pro, Trunk eccentric exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Ankara City Hospital Bilkent
Spinal Cord Injuries, Exercise Program
Exercise Program for Individuals With SCI in Community
Patients with spinal cord injury (SCI) who have reduced mobility have difficulty exercising on their own without proper guidance in the community.
- Conditions
- Spinal Cord Injuries, Exercise Program, Rehabilitation
- Trial name
- NCT06524453
- Testing
- Wheelchair accessible exercise program
- Where
- South Korea
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Spinal Cord Injuries, Anxiety
Biofeedback Treatment of Anxiety Associated With Chronic Spinal Cord Injury
The purpose of this research is to test the feasibility of an intervention using biofeedback to treat stress and anxiety among individuals with tetraplegia.
- Conditions
- Spinal Cord Injuries, Anxiety, Stress, Tetraplegia
- Trial name
- NCT03975075
- Testing
- Psychophysiological monitoring, Biofeedback training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Craig Hospital
Neurogenic Bladder, Incomplete Spinal Cord Injury
Effects Of App-Supported Transitional Care On Neurogenic Bladder In Spinal Cord Injury Patients
This is a single-blind randomized controlled trial for patients with neurogenic bladder after incomplete spinal cord injury. Participants are randomly divided into two groups.
- Trial name
- NCT07641101
- Testing
- Mobile Application Based Transitional Care, routine standardized inpatient bladder nursing
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Xiamen University
Neoplasm Metastasis, Spinal Cord Diseases
Laser Interstitial Thermal Ablation and Stereotactic Radiosurgery for Patients With Spine Metastases
The purpose of this research is to combine two complementary modes of treatment, spinal interstitial laser ablation and stereotactic spine radiosurgery (SSRS) for the treatment for spinal tumors near the spinal cord with an…
- Conditions
- Neoplasm Metastasis, Spinal Cord Diseases, Spinal Cord Compression, Spinal Cord Tumor
- Trial name
- NCT05023772
- Testing
- Stereotactic Laser Ablation, Stereotactic Radiosurgery, MRI guided laser ablation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Henry Ford Health System
Electric Stimulation Therapy, Bowel Dysfunction
The Effect of NMES on Bowel Management in People With Chronic SCI
It has been reported that 62% of all people with Spinal Cord Injury (SCI) have experienced faecal incontinence and that neurogenic bowel dysfunction (NBD) is a major sequela.
- Conditions
- Electric Stimulation Therapy, Bowel Dysfunction, Spinal Cord Injuries, Defecation Disorder
- Trial name
- FES_Bowel (NCT04914975)
- Testing
- Neuromuscular electrical stimulation
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Spinal Cord Injuries, Neuropathic Pain
Cannabinoids and an Anti-inflammatory Diet for the Treatment of Neuropathic Pain After Spinal Cord Injury
Neuropathic pain is a common complication following spinal cord injury (SCI) that significantly decreases quality of life. Treatment options are limited, and current treatments can have significant side effects.
- Trial name
- CATNP (NCT04057456)
- Testing
- Anti-inflammatory diet, Nabilone Capsules
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Eldon Loh, MD
Shoulder Pain, Spinal Cord Injury
Safe and Effective Shoulder Exercise Training in Manual Wheelchair Users With SCI
This study will compare two exercise programs in an interventional study for manual wheelchair users with spinal cord injury and shoulder pain.
- Trial name
- NCT02777281
- Testing
- Shoulder pain and SCI, Shoulder pain and able bodies
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Minnesota
Spinal Cord Injuries
Kayak Ergometer Training in Individuals With Spinal Cord Injury
One of the main objectives in spinal cord injury rehabilitation programs is the improvement of trunk control in order to achieve independence, to prevent complications and, in specific cases to walk.
- Trial name
- NCT03531164
- Testing
- kAYAK ERGOMETER GROUP, CONTROL GROUP
- Where
- Mexico
- Volunteers
- 18 people
- Sponsor
- Instituto Nacional de Rehabilitacion
Amyotrophic Lateral Sclerosis
Low Dose IL-2 in the Treatment of Immune-associated ALS Syndrome
The purpose of this study was to evaluate the efficacy and safety of low-dose IL-2 in the treatment of immunorelated ALS syndrome.
- Trial name
- NCT04952155
- Testing
- IL-2
- Where
- China
- Volunteers
- 13 people
- Sponsor
- Peking University Third Hospital
Spinal Cord Injury
Indego® Exoskeleton; Assessing Mobility for Persons With Spinal Cord Injury (SCI).
This study will evaluate the Indego® device for safety and effectiveness at allowing persons with SCI who are non-ambulatory or poorly ambulatory to stand up and walk under a variety of conditions.
- Trial name
- Indego (NCT02202538)
- Testing
- Indego
- Where
- 5 sites in United States
- Volunteers
- 53 people
- Sponsor
- Parker Hannifin Corporation
Spinal Cord Injury, Paraplegia
Exoskeletal-assisted Walking to Improve Mobility, Bowel Function and Cardio-Metabolic Profiles in Persons With SCI
The primary objective of this study is to achieve successful walking skills using exoskeletal walking devices over the course of 36 sessions in 3 months at specific velocities and distances in people with chronic SCI who are…
- Conditions
- Spinal Cord Injury, Paraplegia, Tetraplegia
- Trial name
- EAWSCI (NCT02314221)
- Testing
- Exoskeletal-assisted walking (ReWalk, Ekso)
- Where
- 3 sites in United States
- Volunteers
- 73 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Spinal Cord Injuries (SCI)
Dose Optimization Study of Acute Intermittent Hypoxia in Spinal Cord Injury
This study aims to evaluate how different doses of acute intermittent hypoxia (AIH) affect lower-limb strength, reaction time, and responsiveness in individuals with spinal cord injury (SCI).
- Trial name
- DOSA-SCI (NCT07739992)
- Testing
- Acute Intermittent Hypoxia (AIH) 15, Acute Intermittent Hypoxia (AIH) 23
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Milap Sandhu
Traumatic Brain Injury, Cervical Spinal Cord Injury
Restorative Neuromodulation for Upper Extremity Functions
The objective of this research study is to find the efficacy of trans-spinal electrical stimulation, a non-invasive neurostimulation method to modulate the functions of spinal cord neurocircuits, on improving upper-extremity…
- Trial name
- NCT04183998
- Testing
- Trans-spinal Electrical Stimulation (tsES)
- Where
- Hong Kong
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Spinal Cord Injury
Paraplegic Cycling: Improving Health After Spinal Cord Injury
Surface electrical stimulation has for many years been widely used to retrain paralysed muscle and achieve the functions of standing and stepping.
- Trial name
- NCT00204100
- Testing
- Surface Functional Electrical Stimulation
- Where
- 2 sites in United Kingdom
- Volunteers
- 5 people
- Sponsor
- University of Glasgow
Degenerative Disc Disease(DDD)
Evaluation of the Safety and Effectiveness of the CORUS™ Posterior Cervical Stabilization System 3D (PCSS 3D) for the Treatment of 2-level Cervical Degenerative Disease
The objective of this clinical trial is to evaluate the treatment of patients with two-level cervical degenerative disease using a combination of Anterior Cervical Discectomy and Fusion (ACDF) and Posterior Cervical Fusion (PCF)…
- Trial name
- SECOND (NCT07721493)
- Testing
- Circumferential Cervical Fusion (CCF), Anterior Cervical Discectomy and Fusion
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Providence Medical Technology, Inc.
Spinal Cord Injury
Can Vibration Stimulation of the Foot Sole Activate Leg Muscles?
Participants will be asked to complete three different tests (standing, stepping and assisted walking) and will experience three different experimental conditions during each test.
- Trial name
- NCT02043106
- Testing
- plantar vibration
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Wilfrid Laurier University
Spinal Cord Injury, Neurogenic Bowel
Use of Prokinetics During Inpatient Bowel Care for SCI Patients
Bowel care (BC) is a time-consuming and cumbersome activity of daily living for most individuals with SCI. Previous studies have reported that the average time to complete a BC routine is 45 minutes; 10-20% of SCI individuals…
- Trial name
- NCT02370433
- Testing
- Intravenous Neostigmine and Glycopyrrolate, Transdermal Neostigmine and Glycopyrrolate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Myelopathy Cervical, Cervical Spondylosis
Establishing the Validity and Reliability of a Dexterity Assessment Tool
Every year, thousands of Canadians are diagnosed with degenerative cervical myelopathy (DCM), a form of non-traumatic injury caused by spinal cord compression in the neck.
- Conditions
- Myelopathy Cervical, Cervical Spondylosis, Spinal Cord Compression
- Trial name
- NCT05910593
- Testing
- Dexterity Assessment Tool
- Where
- Canada
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
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