Clinical trials: Central Spinal Cord Syndrome
Spinal Cord Injuries
Transcutaneous Spinal Stimulation: Safety and Feasibility for Upper Limb Function in Children With Spinal Cord Injury
Children who suffer a spinal cord injury in the neck region have difficulty using their hands due to paralysis and/or weakness of their arms and hand muscles.
- Trial name
- NCT04032990
- Testing
- Biostim-5 transcutaneous spinal stimulator
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Louisville
Orthostatic Hypotension, Postural Hypotension
Transcranial Electrical Stimulation for Management of Orthostatic Instability in Acute Cervical Spinal Cord Injury
Individuals with acute cervical spinal cord injury (SCI) can suffer from an excessive and prolonged fall in blood pressure when assuming an upright position, such as transitioning from lying to sitting or standing, a condition…
- Trial name
- NCT01874782
- Testing
- transcranial electrical stimulation
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- University of British Columbia
Spinal Cord Injury
Spinal Cord Injury Registry - North American Clinical Trials Network
The NACTN Spinal Cord Injury Registry is a network of clinical centers collecting de-identified data from patients admitted through the Emergency Department of a NACTN center at the time of injury with an initial (first time)…
- Trial name
- NACTN (NCT00178724)
- Testing
- No Treatment Given
- Where
- 14 sites in United States, Canada
- Volunteers
- 1,500 people
- Sponsor
- Robert G. Grossman, MD
Spinal Cord Injury/Disorder, Stroke
Electrical Stimulation Exercise for Individuals With Lower Limb Paralysis
The purpose of this research study is to evaluate the effectiveness of an exercise training intervention (24-36 sessions) to improve muscle strength and endurance in the lower limbs of individuals with paralysis.
- Conditions
- Spinal Cord Injury/Disorder, Stroke, Multiple Sclerosis, Traumatic Brain Injury
- Trial name
- NCT07768761
- Testing
- Exercise with Electrical Stimulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Louis Stokes VA Medical Center
Stroke, Multiple Sclerosis
Interest of a Musical Intervention on Stress Induced During Botulinum Toxin Injections in Spasticity (MUSIBOT)
Botulinum toxin (BT) injections are a painful treatment frequently used to treat spasticity following central neurological damage (stroke, multiple sclerosis, spinal cord injury, head trauma).
- Conditions
- Stroke, Multiple Sclerosis, Spinal Cord Injury, Head Trauma Injury
- Trial name
- MUSIBOT (NCT06920524)
- Testing
- Intervention group IM-IM
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Spinal Cord Injuries, Tetraplegia
Study Testing Benefits of Ursolic Acid (UA) as a Countermeasure To Myopenia and Insulin Resistance in Chronic Spinal Cord Injury (SCI)
This study will evaluate if Ursolic Acid supplementation may be effective in reducing muscle loss and improving blood sugar control in the SCI community.
- Conditions
- Spinal Cord Injuries, Tetraplegia, Paraplegia, Muscle Loss
- Trial name
- NCT05776862
- Testing
- Ursolic Acid, Strength Training
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Miami
Injuries, Spinal Cord
ReWalk Personal Device Postmarket Study
This study seeks to further evaluate the Multi-Tiered Training Program and to further explore the overall safety profile of the ReWalk Personal Device outside of the institutional setting under conditions of routine medical…
- Trial name
- NCT02944669
- Testing
- ReWalk Personal Device
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- ReWalk Robotics, Inc.
Pressure Ulcers, Spinal Cord Injury
Comparison of HP011-101 to Standard Care for Stage I-II Pressure Ulcers in Subjects With Spinal Cord Injury
The trial will compare the effects of 14 days treatment with HP011 101 versus Standard Care in subjects with Stage I or II pressure ulcers as a complication of spinal cord injury, measured as change from baseline in composite…
- Trial name
- NCT01433159
- Testing
- HP011-101 (Xenaderm Ointment), Standard Care
- Where
- 5 sites in United States
- Volunteers
- 19 people
- Sponsor
- Healthpoint
Stiff-Person Syndrome
Randomized Placebo Controlled Trial of IVIg in Glycine Receptor Antibody Positive Stiff-person Syndrome
This is a randomized double-blind controlled trial of intravenous immunoglobulin (IVIg) for glycine receptor antibody positive (GlyRα1) antibody Stiff Person Syndrome (SPS) spectrum disorders.
- Trial name
- NCT03749096
- Testing
- Intravenous Immunoglobulins, Human
- Where
- United States
- Sponsor
- Mayo Clinic
Spinal Cord Injuries, Sleep Apnea
Psychosocial, Cognitive, and Behavioral Consequences of Sleep-disordered Breathing After SCI
This clinical trial will examine the efficacy of continuous positive airway pressure (CPAP) therapy in improving psychosocial, neurocognitive and behavioral consequences of moderate-to-severe sleep-related breathing disorders…
- Trial name
- NCT04007380
- Testing
- Continuous positive airway pressure (CPAP) therapy
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University Health Network, Toronto
Spinal Cord Injuries
Physical Activity Scale in Individuals With Spinal Cord Injury
The aim of this study was to improve the cultural adaptation and Turkish version of the The Physical Activity Scale for Individuals With Physical Disabilities (PASIPD) and to investigate the validity and reliability of the…
- Trial name
- NCT04234269
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Istinye University
Spinal Cord Injury (=3 Years), Traumatic Brain Injury (TBI) Patients
Evaluation of a Voice-Activated Call Light System for Clients With Limited Upper-Extremity Mobility
The goal of this study is to evaluate whether a voice-activated call light system enables people in a rehabilitation facility who have limited use of their arms and hands to call for help more independently and reliably than with…
- Conditions
- Spinal Cord Injury (=3 Years), Traumatic Brain Injury (TBI) Patients, Healthy Adult Participants
- Trial name
- NCT07873151
- Testing
- voice-activated call light
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Quality Living, Inc.
Spinal Cord Injuries
Longitudinal Assessment of Spinal Cord Structural Plasticity Using DTI in SCI Patients
This study will apply novel magnetic resonance imaging (MRI) techniques to investigation of spinal cord injury (SCI) to learn how nerve fibers repair and neural cells regain ability to control muscle during the rehabilitation.
- Trial name
- NCT03069222
- Testing
- Standard Rehabilitative Treatment
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Spinal Cord Injury
Epidemiology and Cost of Falls in Veterans With a Spinal Cord Injury
Brief Summary Detailed Description Background: A multitude of risk factors for falling has been reported for the elderly, however many of these risk factors are not applicable to persons with a spinal cord injury, who use a…
- Trial name
- NCT00119522
- Where
- 3 sites in United States
- Volunteers
- 702 people
- Sponsor
- US Department of Veterans Affairs
Adaptive Sport in Spinal Cord Injury
Study About Acting of Adaptive Sport in Musculoskeletal, Cardiovascular System and the Quality of Life of Individuals With Spinal Cord Injury Through Biomedical Instrumentation
The hypothesis is to the fulfillment of canoeing, handbike and conventional physiotherapy activities the groups could show improvement in muscle strength of the arms, decreased resistance of the lower limbs (spasticity), improved…
- Trial name
- Adaptive sport (NCT02177929)
- Testing
- adapted canoeing, hadbike and conventional physiotherapy
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Universidade do Vale do Paraíba
Acute Flaccid Paralysis, AFP
Pattern of AFP in Chhidren Admitted at Sohag University Hospital
This study is observational study aims to study the Clinical profile, Possible risk factors and Outcome of Acute flaccid paralysis in children at Sohag University Hospital.
- Conditions
- Acute Flaccid Paralysis, AFP, Gullian Barre Syndrome, Transverse Myelitis
- Trial name
- AFP-SUH (NCT07775066)
- Testing
- Observitional follow-up
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mohamed Aboelhamd Ali
Spinal Cord Injury (SCI), Initial Encounter
Assessment of Neural Signals for the Control of Assistive Devices
The study will investigate the use of motor intention-based cortical signals to trigger epidural spinal cord stimulation (ESCS) with individuals with SCI.
- Trial name
- NCT06533969
- Testing
- Epidural Spinal Cord Stimulation, Electrocorticographic, Electroencephalographic
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- University of Miami
Spinal Cord Injuries, Neuropathic Pain
Cannabinoids and an Anti-inflammatory Diet for the Treatment of Neuropathic Pain After Spinal Cord Injury
Neuropathic pain is a common complication following spinal cord injury (SCI) that significantly decreases quality of life. Treatment options are limited, and current treatments can have significant side effects.
- Trial name
- CATNP (NCT04057456)
- Testing
- Anti-inflammatory diet, Nabilone Capsules
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Eldon Loh, MD
Spinal Cord Injuries
Improving Adherence to Spinal Cord Injury Exercise Guidelines Using Smartphone Technology and E-coaching
The goal of this research is to increase physical activity among individuals with a spinal cord injury (SCI) through a customized, interactive smartphone-based health app and e-coaching using three phases: (1) leading focus…
- Trial name
- NCT05424172
- Testing
- Stage-I, Group 1: Self monitoring using Non-interactive App, Stage-I, Group 2: Self monitoring using Interactive App, Stage-II, Groups 1a/2a: E-Coaching 1x per month
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries (SCI), Urinary Bladder, Neurogenic
Effect of Urethral Balloon Dilatation on Urinary Retention After Spinal Cord Injury
Trial Objectives: This clinical trial aims to explore whether ultrasound - guided urethral balloon dilation can effectively improve the micturition function of patients with urinary retention after spinal cord injury, and to…
- Conditions
- Spinal Cord Injuries (SCI), Urinary Bladder, Neurogenic, Urinary Retention
- Trial name
- NCT06978205
- Testing
- Urethral Balloon Dilation, intermittent catheterization, Acupuncture treatment
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Qilu Hospital of Shandong University
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