Clinical trials: Central Venous Catheter
Infant, Premature, Anticoagulants
Heparin Versus no Heparin on Duration of Peripherally Inserted Central Catheter (PICC) Patency in Neonates
Background: Heparin is an anticoagulant commonly used in the neonatal population as a means to prevent catheter related occlusion and malfunction by thrombosis (clot).
- Conditions
- Infant, Premature, Anticoagulants, Thrombosis
- Trial name
- NCT00879957
- Testing
- heparin, No heparin
- Where
- United States
- Sponsor
- The University of Texas Health Science Center at San Antonio
Infection
Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter
RATIONALE: Giving the antibiotic teicoplanin by infusion and allowing bacteria to be exposed to the antibiotic for a longer period of time may be effective in preventing or controlling septicemia.
- Trial name
- NCT00024453
- Testing
- teicoplanin
- Where
- 21 sites in Ireland, United Kingdom
- Volunteers
- 1,360 people
- Sponsor
- Children's Cancer and Leukaemia Group
Adult Cancer Patients, Right Atrial Clot
A Study of Cardiac Magnetic Resonance Imaging (CMR) for Evaluating Catheter-Associated Right Atrial Clot in People With Cancer
The researchers are doing this study to see how well cardiac magnetic resonance imaging (CMR) scans can be used to examine the properties of central venous catheter-associated right atrial clot (RA clot).
- Trial name
- NCT07549477
- Testing
- Cardiac MRI
- Where
- 7 sites in United States
- Volunteers
- 150 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Catheterization, Central Venous
Can Ultrasound be Used to Verify CVC Position and to Exclude Pneumothorax?
The purpose of this study is to determine if emergency room physicians can use bedside ultrasound to quickly determine the proper placement of a central venous catheter and to evaluate for complications such as a punctured lung.
- Trial name
- NCT00388375
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Christiana Care Health Services
Pulmonary Embolism, Acute Pulmonary Embolism
CLEANer Aspiration for Pulmonary Embolism
To evaluate the safety and efficacy of the Cleaner™ Pro Thrombectomy System for aspiration thrombectomy in patients with acute pulmonary embolism (PE).
- Conditions
- Pulmonary Embolism, Acute Pulmonary Embolism, Cardiovascular Diseases, Venous Thromboembolism
- Trial name
- CLEAN-PE (NCT06189313)
- Testing
- Cleaner Pro Thrombectomy System
- Where
- 14 sites in United States
- Volunteers
- 125 people
- Sponsor
- Argon Medical Devices
Central Line Complication
Virtual Reality With Ultrasound Versus Ultrasound For Central Line Insertion
We aim to compare the use of ultrasound guidance alone versus a magnetically tracked needle to look at the time taken to place a central line, or specifically the time taken to place a needle in the internal jugular vein prior to…
- Trial name
- NCT01877031
- Testing
- Virtual Reality, Ultrasound
- Where
- Canada
- Volunteers
- 192 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Acute Myocardial Infarction, Restenoses, Coronary
Abbott Vascular Medical Device Registry
The AV-MDR is a prospective, non-randomized, open-label, multi-center registry. The purpose of the AV-MDR study is to proactively collect and evaluate clinical data on the usage of the devices in scope within their intended use…
- Conditions
- Acute Myocardial Infarction, Restenoses, Coronary, Coronary Artery Lesions, Venous Embolism
- Trial name
- AV-MDR (NCT04573660)
- Testing
- Coronary and peripheral stents, Pacing catheters, Vascular plugs
- Where
- 37 sites in United States, Australia and 12 more
- Volunteers
- 3,784 people
- Sponsor
- Abbott Medical Devices
Hemodynamics, Central Venous Pressure
Reliability of Central Venous Pressure Measurements
The purpose of this study is to compare CVP measurements from CICCs and PICCs. The investigators will also evaluate whether or not the duration of CICC placement affects the differences in CVP measurements between the CICCs and…
- Trial name
- CVP (NCT01116973)
- Testing
- PICC
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of Oklahoma
Insertion Depth of Central Venous Catheter
The Practical Use of Transthoracic Echocardiography for Obtaining an Optimal Depth of Internal Jugular Venous Catheters in Infants
To test if transthoracic echocardiography is useful for correct positioning of central venous catheters in infants with congenital heart disease
- Trial name
- NCT01763229
- Testing
- transthoracic echocardiography
- Volunteers
- 108 people
- Sponsor
- Seoul National University Hospital
Central Venous Access Complications
Immediate Mechanical Complications After Central Venous Catheterization
The goal of this observational study is to determine the incidence of immediate mechanical complications after central venous catheterization and to explore factors associated with major mechanical complications in adolescent and…
- Trial name
- CATH-RISK (NCT07367620)
- Testing
- Central Venous Catheterization
- Where
- Sweden
- Volunteers
- 29,114 people
- Sponsor
- Thomas Kander
Health Care Associated Infection, Ventilator Associated Pneumonia
Daily Chlorexidine Bath for Health Care Associated Infection Prevention
Cluster randomized controlled trial comparing two bathing strategies in critically ill patients. The intervention group will receive daily bathing with chlorhexidine. The control group will receive usual care.
- Conditions
- Health Care Associated Infection, Ventilator Associated Pneumonia, Central Line-associated Bloodstream Infection (CLABSI), Catheter-Associated Urinary Tract Infection
- Trial name
- CLEAN-IT (NCT05485051)
- Testing
- 2% chlorhexidine digluconate solution with surface-active agents, Usual Baths
- Where
- 16 sites in Brazil
- Volunteers
- 15,730 people
- Sponsor
- Hospital do Coracao
Pneumothorax Iatrogenic Postprocedural, Malposition, Central Venous Catheter
Comparison of Bedside Ultrasound With Chest X-ray for Confirmation of Central Venous Catheter Position
Background: Insertion of a central venous catheter (CVC) could lead to a variety of complications. To detect those complications, Chest X-ray (CXR) is still the reference standard.
- Trial name
- COMBUX (NCT02959203)
- Where
- Netherlands
- Volunteers
- 750 people
- Sponsor
- Amsterdam UMC, location VUmc
Venous Thrombosis
Peripherally Inserted Versus Centrally Inserted Central Venous Catheters in the Neurological Intensive Care
The investigators aim to compare the complications between centrally and peripherally inserted central venous catheters in neurological intensive care unit patients.
- Trial name
- PICNIC (NCT01495429)
- Testing
- Central venous catheter
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Michigan
Lymphoma, Acute Lymphoblastic Leukemia
A Study of the Safety and Effectiveness of Apixaban in Preventing Blood Clots in Children With Leukemia Who Have a Central Venous Catheter and Are Treated With Asparaginase
The purpose of this study is to compare the effect of a blood thinning drug called Apixaban versus no administration of a blood thinning drug, in preventing blood clots in children with leukemia or lymphoma.
- Trial name
- NCT02369653
- Testing
- Apixaban, No systemic anticoagulant prophylaxis
- Where
- 96 sites in United States, Australia and 10 more
- Volunteers
- 512 people
- Sponsor
- Bristol-Myers Squibb
Critical Illness
The Effects of Anti-infective Central Venous Catheter on Catheter-related Infection in Critically Patients
The purpose of this study is to investigate the effect of anti-infective central venous catheter(Certofix®Protect) on reducing catheter-related bloodstream infection in critically ill patients in China, and the relationship…
- Trial name
- NCT02645682
- Testing
- anti-infection CVC, normal CVC
- Where
- 2 sites in China
- Volunteers
- 1,818 people
- Sponsor
- West China Hospital
Catheter Obstruction, Vascular Access Devices
Efficacy and Safety of Actilyse 2 mg/ 2 ml in Comparison to Saline Solution in Patients With Central Venous Access Device Occlusion
This is a multicentre, open-label, randomised, phase III study designed to evaluate the efficacy and safety of Actilyse 2 mg/2 ml in the restoration of function of CVAD
- Trial name
- NCT01958164
- Testing
- Actilyse, Saline solution
- Where
- 5 sites in Russia
- Volunteers
- 16 people
- Sponsor
- Boehringer Ingelheim
Central Line-associated Bloodstream Infection (CLABSI), Catheter-related Bloodstream Infection
Effect of Vancomycin After Catheter Replacement
Randomized controlled trial of the effect of a single-dose intravenous Vancomycin after catheter replacement for suspected central line-associated bloodstream infection on resolution of infection in critically ill patients.
- Trial name
- VanCat (NCT04856878)
- Testing
- Vancomycin
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Catheterization, Central Venous, Echocardiography, Transesophageal
Surface Landmarks and C-length as Predictors of Depth of Right IJV Catheter Insertion: A TEE-Guided Study
The primary aim of this study is to derive a prediction rule to estimate the required length for placement of the CVC tip at the mid-point of the SVC from simple anatomical landmarks that are consistent with the known surface…
- Conditions
- Catheterization, Central Venous, Echocardiography, Transesophageal, Anatomic Landmarks, Radiography
- Trial name
- NCT04274881
- Testing
- Catheterization of internal jugular vein
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Difficult Intravenous Access
Central Venous Catheter vs Midline in Difficulty Access Patient - Pilot Trial
Intravenous access is a necessity for nearly all inpatient medical care. Approximately half of hospitalized patients require a peripheral venous catheter (PVC), either to enable administration of medications intravenously or to…
- Trial name
- p-ACCESS-D (NCT06719869)
- Testing
- Midline intravenous catheter, Central Venous Catheter (CVC):
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Region Jönköping County
Catheterization, Central Venous, Catheter-Associated Infections
Prevention of Catheter-Associated Infection With the Skin Disinfectant Octenidine Dihydrochloride
Health-care-acquired infections are of tremendous importance for patients, especially catheter-associated infections. More than 40% of all bloodstream infections are associated with central venous catheters (CVC; catheters which…
- Conditions
- Catheterization, Central Venous, Catheter-Associated Infections, Bacterial Infections, Bacteremia
- Trial name
- NCT00515151
- Testing
- 0.1% Octenidine with 30% 1-propanol and 45% 2-propanol, 74% Ethanol with 10% 2-propanol
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital Freiburg