Clinical trials: Central Venous Catheters
Anesthesia
Evaluation of the Occurrence of Acute Complications Caused by a Central Venous Catheter Placement
It is an observational, prospective, monocentric study. The purpose of the study is to assess the acute complications rate caused by a central venous catheter placement.
- Trial name
- VVC (NCT01405534)
- Where
- France
- Volunteers
- 1,780 people
- Sponsor
- Centre Leon Berard
Catheterization, Central Venous
Can Ultrasound be Used to Verify CVC Position and to Exclude Pneumothorax?
The purpose of this study is to determine if emergency room physicians can use bedside ultrasound to quickly determine the proper placement of a central venous catheter and to evaluate for complications such as a punctured lung.
- Trial name
- NCT00388375
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Christiana Care Health Services
Respiratory Insufficiency, Shock
Comparison of Central and Peripheral Venous Catheters
The purpose of this study is to compare the mechanical and infectious complications of peripheral versus central venous catheters in critically ill patients. Group allocation will be performed by randomization.
- Conditions
- Respiratory Insufficiency, Shock, Coma
- Trial name
- NCT00122707
- Testing
- catheters
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Venous Thrombosis
Study on the Incidence of Early Deep Vein Thrombosis After Peripherally Inserted Central Catheter Insertion
Deep Vein Thrombosis (DVT) is one of the most important complications after Peripherally Inserted Central Catheter (PICC) insertion. This study goals are to understand when and why DVT develops.
- Trial name
- DVT-PICC (NCT02752984)
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Catheter-related Infection
Optimalisation of Therapeutic Drug Monitoring (TDM) of Vancomycin in Patients With Central Venous Port Devices
Recently, it was reported that when vancomycin levels are determined after port sampling, levels can be falsely increased potentially leading to wrong dose adjustments.
- Trial name
- NCT01661361
- Testing
- blood levels
- Volunteers
- 15 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
CLABSI - Central Line Associated Bloodstream Infection, Deep Vein Thrombosis
Tunneled Peripherally Inserted Central Catheter (PICC) in Adult Patients and Associated Outcomes
The aim of this multicenter randomized clinical trial is to compare the tunneling technique of PICC insertion with the non-tunneled insertion technique in the incidence of the combined or isolated outcome of catheter-related…
- Conditions
- CLABSI - Central Line Associated Bloodstream Infection, Deep Vein Thrombosis, Dislodged Catheter, Occlusion
- Trial name
- NCT06365528
- Testing
- Subcutaneous tunnelling, Non-tunnelling
- Where
- Brazil
- Volunteers
- 840 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Anticoagulant-induced Bleeding, Direct Oral Anticoagulant
Peri-procedural Management of Direct Oral Anticoagulants for Central VENOus Catheters in CAncer Patients With Venous Thromboembolism or Atrial Fibrillation Pilot Study
The peri-procedural management of direct oral anticoagulants (DOACs) in persons with cancer (PWC) undergoing tunneled or port central venous catheter (CVC) insertion is a common but understudied clinical problem, with conflicting…
- Conditions
- Anticoagulant-induced Bleeding, Direct Oral Anticoagulant, Cancer, Central Venous Catheter
- Trial name
- VENO CAT (NCT06887270)
- Testing
- Continued DOAC, Interrupted DOAC
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University Health Network, Toronto
Cancer
Risk Factors for Thromboembolic and Infectious Complications Related to Percutaneous Central Venous Catheters in Cancer - Prospective Multicenter Study
The purpose of this study is to identify risk factors for thromboembolic and /or infectious complications in 3,000 patients with solid tumor and receiving a Percutaneous Central Venous Catheter (PCVC).
- Trial name
- ONCOCIP (NCT02025894)
- Where
- 27 sites in France
- Volunteers
- 3,032 people
- Sponsor
- Institut de Cancérologie de la Loire
Thrombosis
Safety and Efficacy of Tissue Plasminogen Activator (tPA) in Neonates and Infants
The purpose of this study is to determine if alteplase is effective in dissolving a clot in a catheter in a large vein (central venous line or PICC line) or artery in infants less than 6 months of age.
- Trial name
- NCT00265005
- Testing
- alteplase
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Louisville
Falls Injury, Readmission Rates
Duke Virtual IntEgrated Workflow
This quality improvement initiative aims to evaluate the implementation, utilization, and impact of virtual care technologies and workflows being implemented at Duke University Health System (DUHS).
- Conditions
- Falls Injury, Readmission Rates, CLABSI - Central Line Associated Bloodstream Infection, Catheter Associated Urinary Tract Infection
- Trial name
- Duke VIEW (NCT07406074)
- Testing
- Co-Care
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Duke University
Nurse Education
The Effect of Virtual Simulation Games on Nursing Students' Knowledge, Skills, Confidence and Satisfaction in CVC Care
This study aims to evaluate the effect of virtual simulation games on developing nursing students' knowledge, skills, confidence, and satisfaction levels regarding central venous catheter care and management.
- Trial name
- CVC (NCT07378384)
- Testing
- Virtual Simulation Game-Based Education, Standard Nursing Education
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Zeynep Kandemir özsoy
Central Venous Catheter
SC vs IC Approach for US-guided SC Vein Catheterization
Patients were randomly divided into two groups: ultrasound-guided (US-guided) in-plane infraclavicular subclavian vein (IP-ISV) and in-plane supraclavicular subclavian vein (IP-SSV) catheterization.
- Trial name
- USIC (NCT04637347)
- Testing
- Catheterization approach
- Where
- Tunisia
- Volunteers
- 110 people
- Sponsor
- University Tunis El Manar
Central Line-associated Bloodstream Infection (CLABSI)
Port Protectors for Prevention of CLABSIs in Respiratory Semi-intensive Care Unit
Central Line-Associated BloodStream Infections (CLABSIs) are responsible for many deaths in the United States annually. Several collaboratives have demonstrated the preventability of these infections.
- Trial name
- NCT03486093
- Testing
- Training and retraining to GAVECELT "bundle" recommendations plus port protector, Training and retraining to GAVECELT "bundle" recommendations
- Volunteers
- 132 people
- Sponsor
- Catholic University of the Sacred Heart
Therapeutic Education Program, Prevention
Adherence and Understanding of a Therapeutic Education Program for Patients With Central Venous Access (EDUVVC)
The aim of this project is to evaluate, in a prospective cohort of PICC line patients, adherence to the project and understanding of the messages.
- Trial name
- EDUVVC (NCT06478849)
- Testing
- QUESTIONNAIRES
- Where
- France
- Volunteers
- 105 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Catheter-related Bloodstream Infection
Expanded Access Program for Patients at Risk for Catheter-related Infections Who Are Not Eligible for DefenCath® Clinical Trials
The EAP for DefenCath is designed to provide access to a broader population of adult and pediatric patients using catheters for various serious medical conditions.
- Trial name
- NCT06707480
- Testing
- Taurolidine and Heparin
- Sponsor
- CorMedix Therapeutics
Device Related Infection, Vascular Access Complication
The IVCare Adaptive Platform Trial
The IVCare trial is a multicentre adaptive platform study evaluating interventions to prevent infections and other complications associated with central venous access devices (CVADs) in patients with newly inserted or existing…
- Conditions
- Device Related Infection, Vascular Access Complication, Device Related Sepsis, Catheter Infection
- Trial name
- NCT07587593
- Testing
- Connectors/Caps Domain - Standard of Care, Curos™, ClearGuard™ HD
- Volunteers
- 2,500 people
- Sponsor
- The University of Queensland
Critical Illness
The Effects of Anti-infective Central Venous Catheter on Catheter-related Infection in Critically Patients
The purpose of this study is to investigate the effect of anti-infective central venous catheter(Certofix®Protect) on reducing catheter-related bloodstream infection in critically ill patients in China, and the relationship…
- Trial name
- NCT02645682
- Testing
- anti-infection CVC, normal CVC
- Where
- 2 sites in China
- Volunteers
- 1,818 people
- Sponsor
- West China Hospital
Catheter Related Infections
Safety and Bacteraemia Between Peripherally Inserted and Central Inserted Catheters.
Clinical, prospective, single-center, national trial. open and randomized at 1: 1 to compare the rate of bacteremia associated between non-tunneled Central venous catheter and peripheral inserted central catheter.
- Trial name
- PYCBAC (NCT02538159)
- Testing
- CVC, PICC
- Where
- Spain
- Volunteers
- 247 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Cardiovascular Infections, Peripheral Vascular Disease
Placement of Peripherally Inserted Central Venous Catheters (PICC) in Children Guided by Ultrasound
Aimed to compare the success in the peripheral intravenous puncture (PIP), progression and placement of PICC in children, according to the use of Doppler vascular ultrasound (DVUS) or traditional method; to identify the influence…
- Trial name
- NCT01279642
- Testing
- ultrasound, traditional puncture
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
CLABSI - Central Line Associated Bloodstream Infection, CRBSI - Catheter Related Bloodstream Infection
Neonatal Catheter Lock for Infection Prevention
For newborns admitted to Neonatal Intensive Care Units (NICUs), one of the main risk factors for late-onset sepsis is the presence of a central venous catheter (CVC), which is often essential for the administration of medications…
- Conditions
- CLABSI - Central Line Associated Bloodstream Infection, CRBSI - Catheter Related Bloodstream Infection, Neonatal Sepsis, Late-Onset
- Trial name
- Neo-CLIP (NCT07585188)
- Testing
- Taurolidine 2% lock, Normal saline lock
- Where
- Italy
- Volunteers
- 576 people
- Sponsor
- University of Turin, Italy