Clinical trials: Central Venous Catheters
Acute Pain, Anxiety
The 50:50 Nitrous Oxide vs 2% Lidocaine Challenge
The main goal of the project is to assess pain levels and patient comfort during the administration of a 50:50 Nitrous Oxide/Oxygen gas mixture, in comparison to the same parameters under the standard method used at our…
- Conditions
- Acute Pain, Anxiety, Central Venous Catheter
- Trial name
- NCT07618676
- Testing
- Nitrous Oxide-Oxygen, Lidocaine 2% Injectable Solution
- Where
- Serbia
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Institute for Oncology and Radiology of Serbia
Frailty, Cardiac Surgery
Frailty and Ultrasound-Guided Central Venous Catheterization Difficulty in Adult Cardiac Surgery Patients
This prospective observational study aims to evaluate the association between preoperative frailty and the procedural difficulty of ultrasound-guided internal jugular vein catheterization in adult patients undergoing elective…
- Conditions
- Frailty, Cardiac Surgery, Central Venous Catheter
- Trial name
- FRAILCVC (NCT07701538)
- Testing
- Ultrasound-Guided Internal Jugular Vein Catheterization
- Where
- Turkey (Türkiye)
- Volunteers
- 280 people
- Sponsor
- Ankara City Hospital Bilkent
Central Venous Catheter Care
SKİN PROTECTİVE BARRİER FİLM İN CENTRAL VENOUS CATHETER CARE İN INTENSİVE CARE PATİENTS
This randomized controlled study evaluated the effectiveness of a skin protective barrier film used during central venous catheter (CVC) care in adult intensive care unit patients.
- Trial name
- NCT07855835
- Testing
- Skin Protective Barrier Film, Standard Central Venous Catheter Dressing Care
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Bezmialem Vakif University
Central Line, Central Venous Catheter
Statseal® for Central Venous Catheter Insertion Sites in Critical Care
All participants in this clinical trial will be undergoing surgery and will have a central venous catheter (also known as a central line) placed in the large vein in the neck as part of their routine care.
- Conditions
- Central Line, Central Venous Catheter, Vascular Access, Critical Care
- Trial name
- SCENIC (NCT06451185)
- Testing
- A haemostatic mineral powder product.
- Where
- United Kingdom
- Volunteers
- 451 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Bloodstream Infection Due to Central Venous Catheter, Central Line-associated Bloodstream Infections
Chlorhexidine Bathing in Critically Ill Children
Central line-associated bloodstream infections are associated with increased mortality, morbidity, and length of hospital stay. The incidence has decreased significantly with the strict implementation of preventive bundle cares…
- Trial name
- NCT05995080
- Testing
- clorhexidine gluconate bathing
- Where
- Turkey (Türkiye)
- Volunteers
- 247 people
- Sponsor
- Istanbul Medeniyet University
Central Venous Catheter, Coagulation
Contact Activation of Coagulation in Newly Inserted Central Venous Catheters
A central venous catheter (CVC) is a thin plastic tube placed into one of the body's large veins, typically in the neck or near the clavicle. CVCs are crucial for administering medications, fluids, and secure blood samples.
- Conditions
- Central Venous Catheter, Coagulation, Coagulation Activation, Central Venous Catheter Complications
- Trial name
- CAS-2 (NCT07014722)
- Testing
- MERITMEDICAL Careflow™ Two-Lumen Central Venous Catheter, ARROW Two-Lumen Central Venous Catheter, ARROWg+ard Blue Plus® Two-Lumen Central Venous Catheter
- Where
- Sweden
- Volunteers
- 88 people
- Sponsor
- Thomas Kander
Pediatric Cancer, Pediatric Oncology
Central Venous Catheter Care Training for Pediatric Oncology Nurses
The knowledge level of nurses regarding care techniques plays a crucial role in the prevention of central venous catheter-related infections.
- Conditions
- Pediatric Cancer, Pediatric Oncology, Central Venous Catheter, Central Venous Catheter Placement
- Trial name
- NCT07345598
- Testing
- CVC Care Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fenerbahce University
Critical Ill Patients, Central Venous Catheter
Development and Validation of an Ultrasound-Based Difficult Cannulation Risk Score
Ultrasound-guided internal jugular vein (IJV) catheterization is widely used in critically ill patients. Despite ultrasound guidance, difficult catheterization and first-pass failure remain clinically important and may increase…
- Trial name
- ROTATE-ICU (NCT07764562)
- Testing
- IJV Catheterization
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Antalya Health Sciences University
Catheter Malposition, Central Venous Catheterization
Ultrasound Guidance vs. Landmark Technique for Catheter Malposition in IJV Catheterization
Central venous catheterization (CVC) via the internal jugular vein (IJV) is a fundamental procedure in anesthesia and intensive care for hemodynamic monitoring, fluid resuscitation, and vasoactive drug administration.
- Trial name
- NCT07701720
- Testing
- Ultrasound-Guided Technique, Landmark Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Central Venous Catheter, Midline Catheter
CVCs Versus Midline Catheters
The goal of this clinical trial is to learn if midline catheters can reduce adverse patient outcomes in adult patients requiring a single vasopressor.
- Conditions
- Central Venous Catheter, Midline Catheter, Complication of Catheter
- Trial name
- NCT06884176
- Testing
- Ultrasound Guided Central Venous Catheter, Ultrasound Guided Midline Catheter
- Sponsor
- Albert Einstein College of Medicine
Vascular Access Complication, Hemodialysis Access Failure
Optimizing Access Surgery In Senior Hemodialysis Patients
The number of elderly hemodialysis patients is growing. Vascular access complications are a major determinant of the quality of life and health care costs for these vulnerable patients.
- Conditions
- Vascular Access Complication, Hemodialysis Access Failure, Dialysis Access Malfunction, Arteriovenous Fistula
- Trial name
- OASIS (NCT05911451)
- Testing
- Arteriovenous fistula creation, Arteriovenous graft placement, Central venous catheter placement
- Where
- 20 sites in Netherlands
- Volunteers
- 166 people
- Sponsor
- Maastricht University Medical Center
Neoplams, Anxiety
Using Virtual Reality During PICC and PICC-PORT Placement in Cancer Patients
Virtual reality (VR) has increasingly been explored in medical settings as a non-pharmacological intervention for the management of pain and anxiety associated with invasive procedures.
- Conditions
- Neoplams, Anxiety, Pain, Satisfaction
- Trial name
- VR-PICCPORT (NCT07384741)
- Testing
- Virtual reality VR
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Istituto Oncologico Veneto IRCCS
Medical Adhesive Related Skin Injury, Central Venous Catheter
Medical Adhesive and Barrier Products for Preventing MARSI in Central Venous Catheter Dressings
The goal of this clinical trial is to compare three different dressing securement strategies used for central venous catheters (CVCs) to determine which is more effective in preventing medical adhesive-related skin injury (MARSI)…
- Trial name
- NCT07697430
- Testing
- Acrylic Adhesive Tape, Silicone Adhesive Tape, Skin Barrier Film + Acrylic Adhesive Tape
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people
- Sponsor
- Azize Özdaş Gündoğan
Acute Brain Injury, Traumatic Brain Injury
Effect of Central Venous Catheterization on Brain Pressure in Acute Brain Injury Patients
Acute brain injury (ABI) is a serious condition that can cause a dangerous increase in pressure inside the skull (called intracranial pressure, or ICP), which can harm the brain.
- Conditions
- Acute Brain Injury, Traumatic Brain Injury, Intracerebral Hemorrhage, Aneurysmal Subarachnoid Hemorrhage (aSAH)
- Trial name
- CVC-ICP (NCT07704528)
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- Beijing Tiantan Hospital
Catheter-Related Infections, Central Venous Catheters
Advanced Dressings for CVC Infection Prevention in PICU
Randomised, single-blind clinical trial comparing chlorhexidine gluconate-impregnated transparent dressings versus conventional transparent dressings in the prevention of central venous catheter-related bloodstream infections…
- Conditions
- Catheter-Related Infections, Central Venous Catheters, Bloodstream Infection, Pediatric Intensive Care Units
- Trial name
- NCT07175116
- Testing
- 3M™ Tegaderm™ Antimicrobial Transparent Dressing (chlorhexidine gluconate-impregnated), Conventional transparent polyurethane dressing
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- University of Seville
Vasoconstriction, Biomarkers
Immersive VR to Reduce Stress, Anxiety, and Pain During PICC/Midline Placement
Medical and technological advancements allow increasingly complex invasive procedures to be performed on hospitalized patients, improving their survival rates and prognosis.
- Conditions
- Vasoconstriction, Biomarkers, Central Venous Catheters, Midline Catheter
- Trial name
- PICC (NCT07696156)
- Testing
- Immersive Virtual Reality, Peripherally Inserted Central Catheter (PICC), Mepivacaine 2% Injection
- Where
- 4 sites in Spain
- Volunteers
- 202 people
- Sponsor
- diana garcia
Central Venous Catheters, Obesity
A Trial to Study the Influence of Ultrasound Guidance on the Complications of Central Catheter
Central venous catheterization (CVC) in ICU is very common. It is associated with many complications. These complications are now well identified in the literature. They are primarily mechanical, infectious and thrombotic events.
- Trial name
- CATHETER (NCT01154465)
- Testing
- Central Venous Catheter Insertion, Ultrasound guidance
- Where
- France
- Volunteers
- 264 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Undergoing Nonemergent Cardiac Surgery, Central Venous Catheter on the Superior Vena Cava (to Perform ScVO2 Measure)
SvO2 Trigger in Transfusion Strategy After Cardiac Surgery
Current international guidelines suggest a restrictive transfusion strategy, setting that Hb level at 7 g/dl is a reasonable threshold.
- Conditions
- Undergoing Nonemergent Cardiac Surgery, Central Venous Catheter on the Superior Vena Cava (to Perform ScVO2 Measure), Anemia (<9g/dL) Requiring Blood Transfusion, Hemodynamic and Respiratory Stability
- Trial name
- ReTSEACS (NCT02761564)
- Testing
- Red blood cell tranfusion, ScvO2 measure
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Central Venous Catheter, Point of Care Ultrasound (POCUS)
Central Venous Catheter Placement With Thoracic Ultrasound and Intracavity ECG Positioning
The goal of this interventional study is to assess the feasibility of two bedside techniques for confirming central venous catheter (CVC) placement and detecting complications: Intracavity ECG monitoring to confirm internal…
- Conditions
- Central Venous Catheter, Point of Care Ultrasound (POCUS), Intracavitary Electrocardiogram Guiding, Feasibility Studies
- Trial name
- CVC-TIP (NCT07291869)
- Testing
- Intracavity ECG, Thoracic point of care ultrasound
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- York Teaching Hospitals NHS Foundation Trust
Intensive Care (ICU), Central Venous Catheter Related Infections
Impact of Infusion Line Change Frequency on Infectious Complications Related to Central Venous Catheters in the ICU - A Randomized Controlled Trial
In the intensive care unit, patients' care and secure drugs administration require a central venous catheter. These invasive devices can lead to complications, particularly infections.
- Conditions
- Intensive Care (ICU), Central Venous Catheter Related Infections, Critical Care Nursing, Catheter-associated Bloodstream Infections (CLABSI)
- Trial name
- TANDOORI (NCT07183592)
- Testing
- 7-day Infusion set replacement, 4-day infusion set replacement
- Where
- 27 sites in France
- Volunteers
- 2,830 people
- Sponsor
- University Hospital, Angers