Clinical trials: Central Venous Catheters
Patients Indicated for a PICC for Any Medical Condition
The PROOF Study: The PICC Related Obstruction Of Flow Study
The main purpose of this study is to confirm whether the AngioDynamics BioFlo™ Peripherally Inserted Central Catheter (PICC) is associated with less formation of blood clots compared to another commercially available PICC.
- Trial name
- PROOF (NCT01921114)
- Testing
- BioFlo™ Peripherally Inserted Central Catheter (PICC), Bard® Dual-Lumen PowerPICC SOLO2®
- Where
- 5 sites in United States, Canada and 1 more
- Volunteers
- 57 people
- Sponsor
- Angiodynamics, Inc.
Central Venous Catheter Exit Site Infection, Central Venous Catheter Related Bloodstream Infection
A New Securement Method for External Tunneled Central Venous Access Devices (CVAD)
An external tunneled central venous access device (CVAD) is a small plastic tube that is tunneled under the skin into a major vein for long-term use (Figure 1).
- Trial name
- NCT04462861
- Testing
- Central venous access device (CVAD) Snuggie Securement Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
No Specific Conditions Under Study. Primary Focus: Adult Subjects Who Require PICC Placement
Assessment of the Precision of the Sherlock 3CG Tip Positioning System
Phase I determine the location of the peripherally inserted central catheter (PICC) tip upon observation of maximum p-wave amplitude Phase II determine the precision of PICC placement in the Sherlock 3CG group versus the standard…
- Trial name
- STAT-PICC (NCT01275430)
- Testing
- Sherlock 3CG, Blind Placement
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- C. R. Bard
Valvular Heart Disease
Comparison of Goal-directed Algorithms of Hemodynamic Therapy After Combined Valve Repair
Valvular repair and repair surgery is rapidly progressing yet rather challenging aspect of current cardiosurgical practice. Several approaches were introduced into the clinical practice to alleviate systemic inflammatory response…
- Trial name
- NCT01276444
- Testing
- Swan-Ganz catheter, transpulmonary thermodilution + central venous saturation
- Where
- Russia
- Volunteers
- 43 people
- Sponsor
- Northern State Medical University
Wireless Ultrasound, Central Venous Catheter
Wireless US-guided CVC Placement in Infants
Background: Neonates and small infants with congenital cardiac disease undergoing cardiac surgery represent major challenges facing pediatric anesthesia and perioperative medicine.
- Conditions
- Wireless Ultrasound, Central Venous Catheter, Congenital Heart Disease in Children
- Trial name
- NCT04597021
- Testing
- use of a wiresless US transducer
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Infection
Using a Infrared Thermometer to the Early Detection of Catheter Related Infections
This is a pilot study which aims to show the temperatures measured on body surface with an infrared thermometer on inpatients who need a central venous catheter (CVC) for medical care.
- Trial name
- NCT02077816
- Where
- Brazil
- Volunteers
- 39 people
- Sponsor
- University of Sao Paulo
Central Venous Catheterization, Ultrasound
Point of Care Echocardiography Versus Chest Radiography for the Assessment of Central Venous Catheter Placement
A prospective study to compare the use of point of care echocardiography versus routine chest radiography for the assessment of central venous catheter placement.
- Conditions
- Central Venous Catheterization, Ultrasound, Emergency Medicine, Critical Care
- Trial name
- NCT02661607
- Testing
- Point of care echocardiography, Central venous catheter placement, Chest radiography
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Göttingen
Oncology, Medical, Hematologic Disease
Safety of Catheter Lock With or Without Heparin in Implanted Central Venous Catheters
Long-term central venous access devices are considered as safe for the administration of medication as chemotherapy, but are also used for blood sampling.
- Trial name
- NCT00994136
- Testing
- normal saline
- Where
- Belgium
- Volunteers
- 1,100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Atrial Fibrillation
Multi-electrode PulmonarY Vein Isolation Versus Single Tip Wide Area Catheter Ablation for Paroxysmal Atrial Fibrillation (PAF)
The MYSTIC_PAF trial investigates the differences between treatment with a single-tip catheter against a multielectrode catheter in cardiac ablation procedures in patients with paroxysmal atrial fibrillation.
- Trial name
- MYSTIC-PAF (NCT01696136)
- Testing
- Cardiac ablation for Atrial Fibrillation
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- L.V.A. Boersma
Central Venous Catheters
Evaluation of the Occurrence of Early Thrombosis on Central Venous Catheter by Ultrasound in Pediatric Intensive Care Unit
The objective of this study is to prospectively describe the incidence of early venous thrombosis secondary to the placement of a percutaneous central venous catheter, in a pediatric intensive care unit, by systematic ultrasound…
- Trial name
- Thromb-US (NCT04194736)
- Testing
- Ultrasound scan
- Where
- France
- Volunteers
- 81 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Central Line Complication
Comparison Between Supraclavicular And Infraclavicular Approach For Right Subclavian Venous Catheterization
A central venous catheter (CVC) is an indwelling device that is peripherally inserted into a larg central vein for a multitude of indications in major elective surgeries and ICU patients and now it's now with notable advance is…
- Trial name
- NCT05140668
- Testing
- Comparison between Supraclavicular And Infraclavicular Approach For Ultrasound-Guided Right Subclavian Venous Catheterization
- Where
- Egypt
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Sohag University
Central Venous Access Complications
Immediate Mechanical Complications After Central Venous Catheterization
The goal of this observational study is to determine the incidence of immediate mechanical complications after central venous catheterization and to explore factors associated with major mechanical complications in adolescent and…
- Trial name
- CATH-RISK (NCT07367620)
- Testing
- Central Venous Catheterization
- Where
- Sweden
- Volunteers
- 29,114 people
- Sponsor
- Thomas Kander
PICC, Central Venous Catheter
Complications Associated With Central Venous Access in the NSICU: PICC vs CVC
The goal of this study is to determine whether Peripherally Inserted Central Catheter or Centrally Inserted Venous Catheters have lower complication rates in the Neuroscience Intensive Care Unit.
- Conditions
- PICC, Central Venous Catheter, Central Line, Neuro ICU
- Trial name
- NSPVC (NCT02314520)
- Testing
- peripherally inserted central catheter, centrally inserted central catheter
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Milton S. Hershey Medical Center
Behavior, Process, Acceptance
Implementation of Ultrasound Guided Central Venous Catheter Confirmation Protocol
The bedside use of ultrasound after central venous catheter (CVCs) insertion has lagged behind other applications in medicine, thus presenting an opportunity for innovative, evidence-based research that will influence clinician…
- Conditions
- Behavior, Process, Acceptance, Inertia of Accommodation
- Trial name
- DRAUP (NCT04324762)
- Testing
- targetted implementation strategies
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Thrombosis, Venous Thrombosis
Safety and Efficacy Study of Alfimeprase in Subjects With Occluded Central Catheters
The purpose of the study is to compare the safety and effectiveness of alfimeprase to a placebo in restoring function of occluded central catheters.
- Trial name
- NCT00346424
- Testing
- Alfimeprase
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- ARCA Biopharma, Inc.
Upper Extremity Deep Vein Thrombosis, Central Venous Catheter Thrombosis
Thromboprophylaxis With Rivaroxaban In Patients With Malignancy and Central Venous Lines
Purpose of the Pilot Trial: To determine the feasibility of conducting a multicentre randomized open label controlled trial evaluating the use of prophylactic dose rivaroxaban to prevent central venous catheter (CVC) associated…
- Conditions
- Upper Extremity Deep Vein Thrombosis, Central Venous Catheter Thrombosis, Cancer
- Trial name
- TRIM-Line (NCT03506815)
- Testing
- Rivaroxaban 10 MG
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- Ottawa Hospital Research Institute
Blood Stream Infection
Central and Peripheral Venous Catheters Associated Blood Stream Infection in ICU in Assiut University
Catheter related infections (CRIs) were found to be associated with several risk factors, including patient related risk factors such as age, gender, clinical status and catheter related risk factors such as the vascular access…
- Trial name
- NCT03379948
- Testing
- blood culture
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Persistent Atrial Fibrillation
Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System
The ReMATCH Study is a prospective, single arm, open label, multi-center, study utilizing the FARAPULSE PFA System, including the FARAWAVE and FARAPOINT PFA Catheters.
- Trial name
- ReMATCH (NCT06735534)
- Testing
- FARAPULSE™ Pulsed Field Ablation System
- Where
- 41 sites in United States, Australia and 1 more
- Volunteers
- 376 people
- Sponsor
- Boston Scientific Corporation
Catheter Related Complication
Verification of the Correct Insertion of a Central Venous Catheter
The investigators propose a prospective diagnostic validity study in which the correct location of the central venous catheter will be verified by ultrasound and then verified by radiography in the same patient, without modifying…
- Trial name
- NCT06109584
- Testing
- Insertion of central venous catheter
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Consorci Sanitari de Terrassa
Child
Femoral Central Venous Access Comparison of 2 Methods
The purpose of this study is to compare the effectiveness and safety of the installation of femoral central venous catheter (CVC) ultrasound-guided real-time 2D versus the landmark method
- Trial name
- NCT02318940
- Testing
- central venous catheter
- Where
- 2 sites in Chile
- Volunteers
- 99 people
- Sponsor
- University of Chile