Clinical trials: Central Venous Catheters
Central Venous Catheter
Evaluation of Performance Over Dwell Time and Safety of the Central-venous Catheters Certofix® Paed
Central venous catheterisation is a medical technique that has become established over many decades and can be rated as State of the Art.
- Trial name
- NCT05124821
- Testing
- Central venous catheter intended to be used for children during routine clinical practice
- Where
- 3 sites in Germany, Italy
- Volunteers
- 100 people
- Sponsor
- B. Braun Melsungen AG
Patients Cannulated With Both PICC and CICC., The Rapidly Fluctuating Hemodynamics During LT.
Comparison of Central Venous Pressures (CVPs) Measured From Peripherally Inserted Central Catheters (PICC) and CICC in Liver Transplantation Recipients
Background: Central venous pressure (CVP) monitoring from the peripherally inserted central venous catheter (PICC) has not often been used because of the higher inherent resistance of the PICC due to its longer length and…
- Trial name
- PICC (NCT00988871)
- Testing
- PICC, CICC
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- National Cancer Center, Korea
Undergoing Nonemergent Cardiac Surgery, Central Venous Catheter on the Superior Vena Cava (to Perform ScVO2 Measure)
SvO2 Trigger in Transfusion Strategy After Cardiac Surgery
Current international guidelines suggest a restrictive transfusion strategy, setting that Hb level at 7 g/dl is a reasonable threshold.
- Conditions
- Undergoing Nonemergent Cardiac Surgery, Central Venous Catheter on the Superior Vena Cava (to Perform ScVO2 Measure), Anemia (<9g/dL) Requiring Blood Transfusion, Hemodynamic and Respiratory Stability
- Trial name
- ReTSEACS (NCT02761564)
- Testing
- Red blood cell tranfusion, ScvO2 measure
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Central Line Associated Blood Stream Infections (CLABSI)
Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults And Adolescent Participants Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)
This is a Phase 3, randomized, double-blind, controlled, adaptive, 2-arm, multicenter study to demonstrate the efficacy and safety of DefenCath in adult and adolescent participants receiving home Total Parenteral Nutrition (TPN)…
- Trial name
- NCT06822426
- Testing
- (taurolidine and heparin) catheter lock solution, Heparin
- Where
- 24 sites in United States, Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- CorMedix Therapeutics
Time to Insertion, Rates of Complications
Safety Study of Subclavian and Internal Jugular Venous Catheterization
There is no randomized controlled trial to compare the rates of complications associated with internal jugular and subclavian venous catheterization.
- Trial name
- NCT01196962
- Testing
- Central venous catheter
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- E-DA Hospital
Central Venous Catheters/Standards, Ultrasonography/Methods
COMPARISON OF CLASSICAL AND SYRINGE-FREE TECHNIQUES IN ULTRASOUND-GUIDED CENTRAL JUGULAR VENOUS CATHETERIZATION
During central venous catheterization, both in-plane and out-of-plane techniques can be used. In the in-plane technique, the entire needle can be visualized with ultrasound.
- Conditions
- Central Venous Catheters/Standards, Ultrasonography/Methods, Ultrasonography/Standards
- Trial name
- syringe-free (NCT07547397)
- Testing
- out-of-plane technique, in-plane technique
- Volunteers
- 90 people
- Sponsor
- ALİEMAN
Wireless Ultrasound, Central Venous Catheter
Wireless US-guided CVC Placement in Infants
Background: Neonates and small infants with congenital cardiac disease undergoing cardiac surgery represent major challenges facing pediatric anesthesia and perioperative medicine.
- Conditions
- Wireless Ultrasound, Central Venous Catheter, Congenital Heart Disease in Children
- Trial name
- NCT04597021
- Testing
- use of a wiresless US transducer
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Chronic Renal Insufficiency
Intensive Versus Standard Hemodialysis CVC Dysfunction Protocol
Central venous catheters (CVCs) are used for vascular access by approximately 56% of our 380 hemodialysis (HD) patients at the Capital Health Renal Program.
- Trial name
- NCT02474810
- Testing
- Alteplase
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- Nova Scotia Health Authority
Acute Myocardial Infarction, Restenoses, Coronary
Abbott Vascular Medical Device Registry
The AV-MDR is a prospective, non-randomized, open-label, multi-center registry. The purpose of the AV-MDR study is to proactively collect and evaluate clinical data on the usage of the devices in scope within their intended use…
- Conditions
- Acute Myocardial Infarction, Restenoses, Coronary, Coronary Artery Lesions, Venous Embolism
- Trial name
- AV-MDR (NCT04573660)
- Testing
- Coronary and peripheral stents, Pacing catheters, Vascular plugs
- Where
- 37 sites in United States, Australia and 12 more
- Volunteers
- 3,784 people
- Sponsor
- Abbott Medical Devices
Acute Pain, Anxiety
The 50:50 Nitrous Oxide vs 2% Lidocaine Challenge
The main goal of the project is to assess pain levels and patient comfort during the administration of a 50:50 Nitrous Oxide/Oxygen gas mixture, in comparison to the same parameters under the standard method used at our…
- Conditions
- Acute Pain, Anxiety, Central Venous Catheter
- Trial name
- NCT07618676
- Testing
- Nitrous Oxide-Oxygen, Lidocaine 2% Injectable Solution
- Where
- Serbia
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Institute for Oncology and Radiology of Serbia
Home Parenteral Nutrition, Intestinal Failure
Overview of Botriomycoma in Children with a Central Line: Epidemiology, Risk Factors, Treatments
Botriomycomas are frequent benign tumors in children. Their appearance on the central catheter orifice is a known event in clinical practice, but one that has been little studied.
- Conditions
- Home Parenteral Nutrition, Intestinal Failure, Central Line, Botriomycoma
- Trial name
- NCT06708689
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Hospices Civils de Lyon
Prophylactic, Anticoagulation
Prophylactic Anticoagulation for Central Venous Line Insertion in Critically Ill Children
This will be a Prospective, randomized, open- label, parallel-group, center trial, which will include 80 of Children which will be admitted at Pediatric Intensive Care Unit (PICU) of Menoufia university Hospital from August 2026…
- Trial name
- NCT07710482
- Testing
- Enoxaparin
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Procedural Complication, Competence
Ergonomics in Ultrasound Procedures
The study will compare two different positions of the ultrasound machine during simulated CVC positioning. The position of the ultrasound machine will be randomized.
- Trial name
- NCT06417021
- Testing
- Frontal Ultrasound Machine, Lateral Ultrasound Machine
- Where
- Italy
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- University of Padova
Central Venous Catheter Thrombosis, Central Venous Catheter Related Bloodstream Infection
Central Venous Catheter-related Complications in Patients Under Anticancer Treatment
Oncology and hemotology patients under anticancer treatments are exposed to increased risks of central venous catheter-related complications due to the underlying cancer and its treament.
- Conditions
- Central Venous Catheter Thrombosis, Central Venous Catheter Related Bloodstream Infection, Solid Tumor, Hematologic Malignancy
- Trial name
- KTcCHO (NCT05455866)
- Testing
- central venous catheter
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Alpes Leman
Anatomic Abnormality, Internal Jugular Vein
Ultrasound Measurement of RIJV in Patients Between 0-2 Years
After obtaining parental consent ultrasonographic evaluation of right internal jugular vein will be performed in pediatric patients undergoing elective surgeries between 0-2 years of age.
- Conditions
- Anatomic Abnormality, Internal Jugular Vein, Neonates, Infants, Premature
- Trial name
- NCT03604094
- Testing
- Ultrasonographic evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Hemodialysis Access Failure, Kidney Disease, End-Stage
Low-Dose Apixaban Added to Standard Heparin Lock Versus Heparin Lock Alone to Prevent Tunneled Hemodialysis Catheters Dysfunction (APICATH-HD)
This randomized, single-center, PROBE trial evaluates whether adding low-dose apixaban (2.5 mg orally every 12 hours) to standard intraluminal heparin lock prolongs primary functional patency of tunneled hemodialysis catheters…
- Conditions
- Hemodialysis Access Failure, Kidney Disease, End-Stage, Hemodialysis Catheter
- Trial name
- APICATH-HD (NCT07404345)
- Testing
- Apixaban, Heparin sodium lock solution
- Where
- Mexico
- Volunteers
- 54 people
- Sponsor
- Hospital Civil de Guadalajara
Intensive Care Units, Neonatal, Misadventures to Patients During Surgical and Medical Care
SEPREVEN: a Stepped-wedge Randomised Controlled Trial
Adverse events are frequent in Neonatal Intensive Care Units' (NICU) patients and account for a high morbidity and mortality. Possible severe adverse events are central line associated bloodstream infections (CLABSI), ventilator…
- Conditions
- Intensive Care Units, Neonatal, Misadventures to Patients During Surgical and Medical Care, Catheter-related Bloodstream Infection (CRBSI) Nos, Quality of Healthcare
- Trial name
- SEPREVEN (NCT02598609)
- Testing
- Education program for NICU caregivers
- Where
- 12 sites in France
- Volunteers
- 8,000 people
- Sponsor
- Dr Caeymaex Laurence
Brain Arteriovenous Malformation, Brain Vascular Malformations
Safety of Apollo Micro Catheter in Pediatric Patients
This is a clinical trial/study for patients diagnosed with brain arteriovenous malformation (AVM). An AVM is an abnormal connection between the arteries and veins of the brain.
- Conditions
- Brain Arteriovenous Malformation, Brain Vascular Malformations, Vein of Galen Malformation
- Trial name
- NCT02085278
- Testing
- Apollo Micro Catheter device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Surgical Wound
AMBULATE Continued Access Protocol to Evaluate the Cardiva Mid-Bore Venous Vascular Closure System (VVCS)
The objective of the trial is to demonstrate the safety and effectiveness of the Cardiva Mid-Bore Venous Vascular Closure System (VVCS) in sealing femoral venous access sites at the completion of catheter-based procedures…
- Trial name
- NCT03573206
- Testing
- Cardiva Mid-Bore Venous Vascular Closure Device (VVCS)
- Where
- 3 sites in United States
- Volunteers
- 168 people
- Sponsor
- Cardiva Medical, Inc.
Patient Safety During Central Venous Catheterization
Direct Measurement of Ideal Depth of Central Line
Total of 89 patients undergoing elective cardiac surgery will be enrolled. Right CVC insertion begins at their intersection of the cricoid cartilage level and the triangular point where the sternal head of the SCM muscle meets…
- Trial name
- NCT03116724
- Testing
- central venous catheterization through Rt. IJV
- Where
- South Korea
- Volunteers
- 89 people
- Sponsor
- Keimyung University Dongsan Medical Center