Clinical trials: Cephalalgia
Post-Dural Puncture Headache, Hypotension
Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean Section
The goal of this clinical trial is to compare different approaches of spinal anesthesia in pregnant females who are having cesarean section.
- Conditions
- Post-Dural Puncture Headache, Hypotension, Spinal Shock, Hematoma
- Trial name
- NCT05637645
- Testing
- Midline Approach, Paramedian Approach, Taylors approach
- Where
- 4 sites in Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bahawal Victoria Hospital Bahawalpur
Migraine
Effectiveness and Neural Mechanism of Naoan Dripping Pills for Migraine
This is a randomized, double-blind, placebo-controlled clinical trial. Its main purpose is to investigate the effects and neural mechanism of Naoan dripping pills on migraine patients by utilizing fMRI and DTI method, as well as…
- Trial name
- ENMNM (NCT03175900)
- Testing
- Naoan dripping pills
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Dongzhimen Hospital, Beijing
Episodic Migraine, Chronic Migraine
CGRP Inhibition, Autonomic Function, and Migraine
The purpose of this clinical study is to better understand the function of the autonomic nervous system in patients with migraine. We aim to understand whether the autonomic functions change depending on the migraine status (i.e.
- Trial name
- CGRP-1 (NCT04628429)
- Testing
- Erenumab, Galcanezumab, Fremanezumab
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Migraine
Staccato Loxapine in Migraine (in Clinic)
The objective of this trial is to assess the efficacy and safety of Staccato Loxapine in patients with migraine headache with or without aura in a clinical setting.
- Trial name
- NCT00489476
- Testing
- Staccato Loxapine
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Alexza Pharmaceuticals, Inc.
Post Dural Puncture Headache
Post Dural Puncture Headache After Accidental Dural Puncture
Epidural anesthesia is associated with potential risks and complications, post dural puncture headache (PDPH) one of the most recognized with epidural or spinal anesthesia.
- Trial name
- NCT01448590
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Migraine, Migraine Headache
The Impact of Acupuncture on Biomarkers of Brain Injury and Inflammatory Response in Migraine
Migraine is more than just a headache-it can involve changes in the brain and inflammation. Recent research suggests that acupuncture may help by calming pain signals and reducing inflammation in the body.
- Conditions
- Migraine, Migraine Headache, Migraine Headache, With or Without Aura, Migraine in Adults
- Trial name
- ACUPMIGRAINE (NCT07292506)
- Testing
- Standard acupuncture, Electroacupuncture, Laser Acupuncture
- Where
- Slovenia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Headache
Vitamin D Plasma Level and Its Role in Headache
To date there are conflicting data concerning a correlation between plasma vitamin D levels and headache. The aim of this study was to evaluate plasma vitamin D levels in patients with headache admitted to the Center of Headache…
- Trial name
- VITDHEAD (NCT02467127)
- Testing
- vitamin D supplementation
- Where
- Italy
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Catanzaro
Primary Headaches (Migraines, Tension, Cluster Headaches)
Osteopathic Manual Therapy (OMT) and Brain Structure and Function in Primary Headache Patients: A Pilot Study
Chronic headaches are associated with changes in brain structure and function that may be associated with increased suffering and disability.
- Trial name
- NCT06841627
- Testing
- Osteopathic Manipulative Therapy
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Headache, Migraine
Natriuretic Peptide's Headache Inducing Characteristics and Effects on the Cerebral Blood Flow
To investigate headache score and accompanying symptoms during and after infusion of the natriuretic peptides.
- Trial name
- NCT01637662
- Testing
- Natriuretic peptides
- Where
- Denmark
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Headache
Lokal Cold Application in Nitroglycerin-Induced Headache (NIH)
The study was planned to evaluate the effect of local cold application on headache severity in individuals who received intravenous nitroglycerin treatment, which mostly causes headache due to its vasoditator effect.
- Trial name
- NCT04707586
- Testing
- Cold Application
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Yasemin Kalkan Uğurlu
Tension-Type Headache
Effectiveness of Soft Tissue Mobilization
The aim of this study was to determine the effects of soft tissue mobilization and trigger point release verses stretching in tension-type headache among university students.
- Trial name
- NCT05305703
- Testing
- cervical stretching, soft tissue mobilization
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Headache
The Role of Inflammation and Vasodilatation in PACAP38-induced Headache Using MRI on Healthy Subjects
Studying Pituitary adenylate cyclase-activating peptide 38 (PACAP38) induced headache effects on extra- and intracerebral arteries and pre-posttreated by sumatriptan and ketorolac assessed by magnetic resonance imaging (MRI) on…
- Trial name
- NCT03585894
- Testing
- Sumatriptan, Ketorolac
- Where
- Denmark
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Medication Overuse Headache, Electroacupuncture
Efficacy and Central Mechanisms of Electroacupuncture for Medication Overuse Headache
Acupuncture is commonly used for the prevention of migraine and tension-type headaches, and has been found to be effective in reducing both the frequency and severity of these conditions.
- Trial name
- NCT06802471
- Testing
- electroacupuncture
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Headache
Arabic Version Of Henry Ford Hospital Headache Disability Inventory Questionnaire : Validity, And Reliability
ARABIC VERSION OF HENRY FORD HOSPITAL HEADACHE DISABILITY INVENTORY QUESTIONNAIRE: CROSS-CULTURAL ADAPTATION, VALIDITY, AND RELIABILITY
- Trial name
- NCT06125821
- Testing
- questionnaire
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Migraine, Migraine Disorders
Osteopathic Manipulative Treatment and Migraine Headaches
In this study the investigators hypothesize, that Osteopathic Manipulative Therapy (OMT) will reduce migraine disability and severity scores when compared to standard of care including prophylactic pharmacological agents with…
- Conditions
- Chronic Migraine, Migraine Disorders, Headache Disorders, Headache, Migraine
- Trial name
- NCT04976985
- Testing
- Osteopathic Manipulative Therapy (OMT), Standard of care
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital, Pennsylvania
Intracranial Pressure Increase, Abdominal Pain
Different Intraperitoneal Pressures on Optic Nerve Sheath Diameter in Laparoscopic Surgeries
The aim of this study is to investigate the effects of low and normal intraperitoneal pressures on intraoperative optic nerve sheath diameter in laparoscopic gyneco-oncologic surgeries.
- Conditions
- Intracranial Pressure Increase, Abdominal Pain, Head Pain
- Trial name
- NCT07155109
- Testing
- Low pressure group, Normal pressure group
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Postdural Puncture Headache
Prediction of Post-dural Puncture Headache in Parturients Undergoing Elective Caesarean Section
The parturients are at particular risk of post dural puncture headache (PDPH) because of their sex, young age, and the widespread application of spinal and epidural anesthesia.
- Trial name
- NCT03464253
- Testing
- Performance of the transcranial Doppler (TCD)
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Cervicogenic Headache
Traditional Chinese Cervical Manipulation for Cervicogenic Headache
Background Cervical spondylosis is a prevalent condition. Studies has shown that it is a leading cause for headache, which is termed cervicogenic headache (CGH). The prevlance of CGH among severe headache is 17.5%.
- Trial name
- NCT06434051
- Testing
- Traditional Chinese cervical manipulation
- Where
- 2 sites in Hong Kong
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Cluster Headache
Role of Specific microRNAs in Cluster Headache
Cluster headache (CH) is a primary headache included in the trigeminal autonomic cephalalgias (TACs) according to the International Calssification of Headache Disorder, Third Edition.
- Trial name
- 5*1000 (NCT06503328)
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Chronic Migraine
Prophylactic Treatment With Atorvastatin for Chronic Migraine (ChronicStatinMig)
The main objective of this study is to see whether the favorable preventative effect of Atorvastatin 40mg per day in episodic migraine, that was found previously in three smaller randomized controlled cross-over studies, can be…
- Trial name
- NCT06485336
- Testing
- Atorvastatin 40mg
- Where
- 6 sites in Norway
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital