Clinical trials: Cephalalgia
Tension-Type Headache
The Effect of Specific Strength-Training on Tension-Type Headache in Children 9-17 Years
This study aims at examining muscle strength capacity in neck and shoulder muscles in children and adolescents with and without tension-type headache, and furthermore examining the effect of a 10 week specific strength training…
- Trial name
- NCT01155557
- Testing
- Specific Strength Training, Lifestyle Counseling
- Where
- Denmark
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Migraine
MRI Outcomes of Mindfulness Meditation for Migraine
112 migraine subjects will be initially randomly assigned to Mindfulness-Based Stress Reduction (MBSR) or a Stress Management for Headache group (SMH).
- Trial name
- NCT02133209
- Testing
- Mindfulness Based Stress Reduction, Stress Management for Headaches
- Where
- 2 sites in United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Migraine With Aura
Migraine and Endothelial Dysfunction
Recently, there is evidence that endothelial activation and dysfunction are associated with migraine, especially in female migraineurs with aura.
- Trial name
- NCT01388699
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Gulf War Illness, Persian Gulf War Syndrome
Study of Gulf War Illness (GWI) by Comparing GWI and Healthy Veterans
Determine if: genetic differences of CNDP1 gene the previously defined GWI/Chronic Fatigue Syndrome (GWI/CFS) cerebrospinal fluid proteome contents psychometric other variables can differentiate between veterans of the 1990-1991…
- Trial name
- NCT00810225
- Where
- United States
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Migraine Headache
A Double-Blind Placebo-Controlled Trial of Rozerem in Migraine Headaches
To study the effect of Rozerem, a high affinity MT1 and MT2, low affinity 5-HT2B receptor agonist used for insomnia, as a migraine prophylactic agent.
- Trial name
- NCT00391755
- Testing
- ramelteon
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Charlottesville Neuroscience
Migraine, Epilepsy
High-field MR Imaging in Migraine, Visual Snow and Epilepsy
In this project, the aim is to recruit patients with drug resistant epilepsy and those suffering from migraine. Interestingly, patients suffering from epilepsy are also more often reporting to suffer from migraine.
- Conditions
- Migraine, Epilepsy, Visual Snow Syndrome
- Trial name
- NCT05524493
- Testing
- Structural MRI, Quantitative MRI, Diffusion MRI
- Where
- 2 sites in Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Cluster Headache, Sleep
Actigraphy and Nocturnal Heartrate Variability in Cluster Headache Patients
Cluster headache is one of the most painful headaches, characterized by recurring episodes of unilateral, periorbital pain, which is accompanied by autonomic symptoms that seem to be of both sympathetic and parasympathetic…
- Trial name
- NCT03010189
- Testing
- Actigraphy, Heart-rate variability monitoring, Pupillometry
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nordlandssykehuset HF
Human Volunteers, Migraine
A Drug Interaction Study of the Pharmacokinetics of Topiramate and FLUNARIZINE When Given Together or Separately
The primary purpose of this open-label study is to determine if concomitant therapy with topiramate and flunarizine has any effect on the pharmacokinetics of either drug.
- Trial name
- NCT00752466
- Testing
- Topiramate; flunarizine
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Tension-Type Headache
Forward Head Posture Differences in Tension Headaches
it evaluates forward head posture (craniovertebral angle), resting scapular alignment (upward rotation, anterior tilt, protraction, depression), and dynamic scapular kinematics (upward rotation, anterior-posterior tilt) between…
- Trial name
- NCT07726303
- Testing
- forward head posture , resting scapular alignment and dynamic scapular kinematics
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vasalgia, Headache
The Effect of Sphenopalatine Ganglion Block on Headache and Vasalgia
The purpose of this study is to evaluate the effect of sphenopalatine ganglion block (SPG block) on headache and veisalgia (hangover) the day after attending the metal festival Copenhell.
- Conditions
- Vasalgia, Headache, Hangover
- Trial name
- NCT07060586
- Testing
- Sphenopalatine Ganglion Block
- Where
- Denmark
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Migraine
A Study Investigating the Movement of Lu AG09222 Into, Through, and Out of the Body of Healthy Caucasian, Chinese, and Japanese Participants
The main goal of the study is to learn more about how the body absorbs and eliminates Lu AG09222 after a single dose is injected under the skin.
- Trial name
- NCT05304910
- Testing
- Lu AG09222
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Migraine, Musculoskeletal Pain
Overlapping Pain Trajectory Study
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1.
- Conditions
- Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain
- Trial name
- COPC (NCT05752396)
- Testing
- Conditioned Pain Modulation, Offset Analgesia, Spatial Summation
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Obesity, Rhinitis
Interventional Testing of Gene-environment Interactions Via the Verifomics Mobile Application
The purpose of this study is to study interactions between genes, lifestyle environmental factors like foods, nutritional supplements and non-invasive medical devices and health factors that can be measured without specialized…
- Conditions
- Obesity, Rhinitis, Rhinitis, Allergic, Respiratory Sounds
- Trial name
- NCT02758990
- Testing
- Vitamin A, Vitamin B6, Vitamin C
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Verifomics LLC
Headache, Migraine
EP4-receptor Antagonism and Prostaglandin E2 (PGE2) in a Human Headache Model
The purpose of this study is to determine whether EP-4 receptor antagonist can prevent the headache expected during a Prostaglandin E2 infusion.
- Trial name
- NCT00957983
- Testing
- BGC20-1531
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Migraine
Safety and Pharmacokinetics (PK) Study of Single Ascending Doses of CVT-427 (Zolmitriptan Inhalation Powder) In Healthy Adults
This study is the first study in humans with CVT-427 (zolmitriptan inhalation powder) and is designed to evaluate the safety, tolerability, and PK of single ascending doses of CVT-427 in adult healthy volunteers.
- Trial name
- NCT02609945
- Testing
- zolmitriptan, CVT-427 (zolmitriptan inhalation powder),
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Acorda Therapeutics
Headache Disorder, Sleep Disorder
Analysis of the Prevalence and Characteristics of Concomitant Sleep and Headache Disorders, and the Efficacy of CPAP Treatment for Headache Among Those Patients Diagnosed With Obstructive Sleep Apnea
There is a well-documented but poorly understood relationship between headache disorders (e.g. migraine, cluster headaches, awakening headaches, etc.) and sleep disorders.
- Conditions
- Headache Disorder, Sleep Disorder, Obstructive Sleep Apnea
- Trial name
- NCT00520156
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Migraine Disorders
Effect of Metoclopramide Versus Sumatriptan for Emergency Department Treatment of Migraine Headache
The purpose of this study is to determine which drug makes lower migraine headache
- Trial name
- NCT01791400
- Testing
- metoclopramide, injection,20mg, one time, Sumatriptan, injection, 6 mg, one time
- Where
- Iran
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Migraine, Migraine;Menstrual
The Effect of Topiramate on Etonogestrel Concentrations in Contraceptive Implant Users
A prospective, non-inferiority study to evaluate the pharmacokinetic effect of topiramate on serum Etonogestrel (ENG) levels in contraceptive implant users.
- Conditions
- Migraine, Migraine;Menstrual, Contraception
- Trial name
- NCT03335163
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Headache
Neuromodulation Treatment of Vestibular Migraines
This is a non-randomized pilot study to test the efficacy of neuromodulation via caloric stimulation on vestibular migraines. All subject who meet the study criteria will be in an active treatment group.
- Trial name
- NCT02866084
- Testing
- Device
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Migraine, Chronic Migraine
Pilot Study for a Machine Learning Test for Migraine
This study is a single center, random participant selection, data analyst is blinded to patient identifiers, controlled clinical trial.
- Conditions
- Migraine, Chronic Migraine, Tension-Type Headache
- Trial name
- MLTM (NCT05517200)
- Testing
- Machine Learning Test for Migraine
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Headache Sciences Incorporated