Clinical trials: Cephalalgia
Tension-Type Headache
Effect of Craniocervical Neural Mobilization on Quality of Life in Patients With Primary Tension Headache
this study will be conducted to investigate the effect of craniocervical neural mobilization on quality of life in patients with primary tension headache.
- Trial name
- TTH (NCT05999201)
- Testing
- craniocervical neural mobilization, selected physiotherapy program
- Volunteers
- 30 people
- Sponsor
- Cairo University
Headache Migraine Chronic
Spectacle Tints and Thin-Films for Migraine
Nearly all migraine sufferers report sensitivity to light during a headache and a significant proportion of sufferers report light sensitivity between attacks. Light is also a common trigger for migraine headaches.
- Trial name
- NCT02720211
- Testing
- Gray tinted spectacle lenses, Thin-Film spectacle lenses
- Where
- 4 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Utah
Cervicogenic Headache
Muscle Energy Technique With And Without Myofascial Release in Patients With Cervicogenic Headache
This randomized controlled trial compared the effects of Muscle Energy Technique (MET) with and without Myofascial Release (MFR) in patients with cervicogenic headache.
- Trial name
- NCT07574112
- Testing
- Muscle Energy Technique (MET), Myofascial Release (MFR)
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Lahore
Migraine Disorders
Transnasal Therapy for Acute Migraine Attack
Migraine is a significant health problem in the United States with 34 million Americans suffering from migraine attacks every year. High-flow oxygen has been successfully used in several clinical studies.
- Trial name
- NCT04129567
- Testing
- Humidified oxygen, Dry oxygen, Humidified air
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Migraine, Tension-Type Headache
An Evaluation of Brief Online Hypnosis for Migraine and Tension-type Headaches
This study aims to conduct an initial evaluation of whether a single, online, group-based session of hypnosis followed by self-hypnosis can decrease symptoms of migraine and tension-type headaches as well as improve quality of…
- Trial name
- NCT04523311
- Testing
- Hypnosis., Usual care
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- Canterbury Christ Church University
Acute Migraine, Migraine Headache
Zolmitriptan Nasal Spray Versus Eletriptan in the Acute Treatment of Migraine
The purpose of this study is to Compare the efficacy of zolmitriptan 5 mg nasal spray vs. eletriptan 40 mg tablet in the acute treatment of migraine.
- Conditions
- Acute Migraine, Migraine Headache, Headache Disorders
- Trial name
- NCT01276977
- Testing
- Zolmitriptan 5 mg Nasal Spray, Eletriptan 40 mg tablet
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- California Medical Clinic for Headache
Headache Disorders, Migraine Disorders
Intervention for Sleep and Pain in Youth
This study tests the feasibility, acceptability, and preliminary efficacy of a seven-session cognitive-behavioral therapy intervention to treat sleep and pain problems in youth ages 11-17 with co-morbid headache and insomnia.
- Conditions
- Headache Disorders, Migraine Disorders, Insomnia
- Trial name
- I-SPY (NCT03137147)
- Testing
- Intervention for Sleep and Pain in Youth
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Seattle Children's Hospital
Headaches Associated With Subarachnoid Hemorrhage (SAH)
IA Lidocaine and Methylprednisolone for Headache Associated With Subarachnoid Hemorrhage
Subarachnoid hemorrhage (SAH) is a type of bleeding around the brain that can cause sudden and severe headaches. These headaches can be debilitating and persist for weeks, significantly impacting a patient's comfort and recovery.
- Trial name
- LIMSAH (NCT07054801)
- Testing
- Lidocaine hydrochloride, Methylprednisolone sodium succinate
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Daniel Raper, MBBS
Headache Disorders, Primary
The Effects of Connective Tissue Massage and Lifestyle Modifications in Adolescents Tension Type Headache
The purpose of this study is to investigate the effects of connective tissue massage and lifestyle modifications in adolescents tension type headache, pain severity, pain duration, pain frequency and quality of life and pressure…
- Trial name
- NCT02549300
- Testing
- Connective tissue massage
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Multiple Sclerosis, Quality of Life
Impact of Exercise on "Invisible" Symptoms and Quality of Life in Multiple Sclerosis Individuals
Patients with multiple sclerosis (MS) struggle on a daily basis with accompanying, "Invisible" symptoms like primary fatigue, pain and emotional-cognitive disorders.
- Conditions
- Multiple Sclerosis, Quality of Life, Motivation, Pain
- Trial name
- NCT03768830
- Testing
- Exercise training
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rijeka
Episodic Migraine
12-Week Placebo-controlled Study of Atogepant for the Preventive Treatment of Migraine in Participants With Episodic Migraine
To evaluate the safety and tolerability of atogepant 30 mg and 60 mg once a day for the prevention of migraine in participants with episodic migraine.
- Trial name
- NCT03777059
- Testing
- Atogepant
- Where
- 138 sites in United States
- Volunteers
- 910 people
- Sponsor
- Allergan
Migraine With Aura, Patent Foramen Ovale
Comorbidities Associated With Migraine and Patent Foramen Ovale (CAMP)
The purpose of the study is to compare the rate of comorbidities associated with migraine aura (MA) between persons who have a large circulatory right-to-left shunt (RLS) and those who do not have RLS.
- Trial name
- CAMP (NCT01257880)
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Swedish Medical Center
Post-Traumatic Headache
Prazosin for Post-Concussive Headaches
Mild traumatic brain injury (mTBI) caused by blast effects of explosive devices has been called the "signature injury" of soldiers who served in the Iraq and Afghanistan conflicts.
- Trial name
- NCT02965027
- Testing
- Prazosin
- Where
- 2 sites in United States
- Volunteers
- 89 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Chronic Headache, Migraine Headache
A Preliminary Investigation of the Efficacy of Aromatherapy in Reducing Discomfort in Youth With Chronic Headache
The purpose of this study is to preliminarily establish the extent to which a brief aromatherapy intervention incrementally improves subjective and objective indicators of discomfort (pain, anxiety, and heart rate variability)…
- Conditions
- Chronic Headache, Migraine Headache, Headache
- Trial name
- NCT02440997
- Testing
- aromatherapy, foot bath
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Children's Mercy Hospital Kansas City
Myalgia, Muscle Pain
Concentration of Receptors With Affinity for Cannabidiol and Cannabinol and the Effect on Chronic Orofacial Pain of Muscle Origin
The main aim of the presented project will be to examine the concentration of selected receptors (CB1, CB2, TRPV-1) showing affinity for binding to cannabidol (CBD) and cannabinol (CBN) in blood samples collected from people with…
- Conditions
- Myalgia, Muscle Pain, Orofacial Pain, Headache, Tension
- Trial name
- NCT06405646
- Testing
- Blood CB1, CB2, TRPV-1 concentration measurement
- Where
- Poland
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Headache Disorders, Post-Concussion Syndrome
Can Targeted Education Impact the Current Standard of Care in Patients With Mild Traumatic Brain Injury?
The study will ask the question as to whether or not it is possible to deliver education material to patients with a mild traumatic brain injury in a consistent matter.
- Conditions
- Headache Disorders, Post-Concussion Syndrome, Mild Traumatic Brain Injury
- Trial name
- NCT03391583
- Testing
- Education
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Unity Health Toronto
Headache, Persistent Idiopathic Facial Pain
Transnasal Versus Suprazygomatic SPG Block in Persistant Idiopathic Facial Pain
The International Headache Society defines persistent idiopathic facial pain (PIFP) as persistent facial pain that does not have the characteristics of cranial neuralgia, is blunt, persistent, persistent, bothersome and not…
- Trial name
- NCT06496841
- Testing
- Transnasal Sphenopalatine ganglion block, Ultrasound-guided suprazygomatic sphenopalatine ganglion block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Diskapi Teaching and Research Hospital
Migraine
Two Rizatriptan Prescribing Portions for Treatment of Migraine
The primary objective of this study is to evaluate a clinical limit (CL) of rizatriptan (9 rizatriptan 10mg Orally Disintegrating Tablet (ODT) per month) versus (vs.) a formulary limit (FL) of rizatriptan (27 rizatriptan 10mg ODT…
- Trial name
- NCT00397254
- Testing
- rizatriptan
- Where
- 10 sites in United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Clinvest
Headache, Headache Disorders
Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Headache Disability Questionnaire
The purpose of this study was to investigate cultural adaptation, reliability and validity of the Turkish version of the Headache Disability Questionnaire (HDQ).
- Conditions
- Headache, Headache Disorders, Headache, Migraine, Headache, Tension
- Trial name
- NCT04736654
- Testing
- Survey study
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Gazi University
Cerebrovascular Accident
Headache Study to Compare Aggrenox Full Dose and Reduced Dose
Tolerability of a four weeks treatment with Aggrenox® modified release capsules b.i.d, compared to reduced dose during the first two weeks of treatment in a double-blind, randomized controlled parallel group comparison trial…
- Trial name
- NCT00274586
- Testing
- Aggrenox® modified release capsules
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Boehringer Ingelheim
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