Clinical trials: Cephalalgia
Tension-Type Headache
Diacutaneous Fibrolysis, Effects on Tension Type Headache
Tension Type Headache (TTH) is a frecuent type of headache disorder (about 1 person in 5 worldwide). Individuals with TTH typically present pericraneal tenderness and an increased cervical muscle tone.
- Trial name
- NCT03056131
- Testing
- Diacutaneous Fibrolysis
- Volunteers
- 82 people
- Sponsor
- Sara Cabanillas Barea
Influenza
Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults - T705US316
The purpose of this study is to determine if favipiravir is effective in reducing the time to resolution of influenza symptoms.
- Trial name
- NCT02026349
- Testing
- favipiravir
- Where
- 225 sites in United States, Australia and 12 more
- Volunteers
- 860 people
- Sponsor
- MDVI, LLC
Menstrual Migraine
Intracranial Pressure During Migraine
An increase in intracranial pressure (ICP) during migraine attacks is possible and could contribute to pain initiation and maintenance. From now on, it was not possible to measure ICP in a non-invasive way.
- Trial name
- MigICP (NCT03152305)
- Testing
- Intracranial pressure variations
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Migraine
A Study to Evaluate the Efficacy and Safety of Eptinezumab Administered Intravenously in Participants Experiencing Acute Attack of Migraine
The purpose of this study is to evaluate the efficacy and safety of eptinezumab administered intravenously in participants experiencing an acute attack of migraine.
- Trial name
- RELIEF (NCT04152083)
- Testing
- Eptinezumab
- Where
- 57 sites in United States, Georgia
- Volunteers
- 485 people
- Sponsor
- H. Lundbeck A/S
Migraine
Trans-diagnostic Cognitive-behavioral Therapy for Treatment of Migraine
Migraine headache is one of the disabling conditions that may be associated with decreased quality of life, anxiety and depression.
- Trial name
- NCT03701477
- Testing
- Trans-diagnostic cognitive-behavioral therapy, General relaxation/stress management therapeutic session
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Isfahan University of Medical Sciences
Migraine
Safety and Tolerability of Frovatriptan to Prevention of Menstrually Associated Migraine (MAM) Headaches
In this open-label, multi-center study, patients were treated with frovatriptan for a maximum of 12 perimenstrual periods (PMPs).
- Trial name
- MAM (NCT01035983)
- Testing
- Frovatriptan 2.5 mg
- Where
- 5 sites in Germany, Hungary and 3 more
- Volunteers
- 550 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Headache
Medical Therapies for Chronic Post-Traumatic Headaches
To determine if propranolol, amitriptyline, or topiramate decreases headache frequency in patients with chronic post-traumatic headaches.
- Trial name
- NCT00862095
- Testing
- Propranolol, Amitriptyline, Topiramate
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Madigan Army Medical Center
Posttraumatic Headache
Safety and Efficacy of Botulinum Toxin A in Patients With Posttraumatic Headache
The study is an investigator-initiated randomized, placebo-controlled, double-blind, parallelgroup trial. Eighty subjects with PTH will be included and randomized 1:1 for treatment with BTX-A or placebo (isotonic saline).
- Trial name
- NCT06839118
- Testing
- Botox 200 UNT Injection
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Danish Headache Center
Central Post-stroke Pain
Structural and Functional Grey and White Matter Changes in Patients With Pain Disorders
The goal of this observational study is to examine the association between exact lesion location and presence of thalamic CPSP (Central post-stroke pain) in a larger number of patients after thalamic stroke.
- Trial name
- NCT05679297
- Testing
- Quantitative sensory testing (QST), Magnetic resonance imaging (MRI), Clinical interview/exam
- Where
- Switzerland
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Migraine
Comparison of Two Different Migraine Acupuncture Treatment
Headache is one of the most common clinical problems. Conventional drug therapy is more successful when complementary and integrative medicine approaches are combined to conventional treatment, as traditional Chinese medicine…
- Trial name
- NCT05351918
- Testing
- acupuncture
- Where
- Slovenia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Migraine
Puberty, Sex Hormones and Pain Sensitivity in Adolescents With Migraine
The purpose of this research study is to investigate the relationships between sex hormone levels and experimental pain sensitivity and migraine severity will be examined.
- Trial name
- IHS (NCT05738213)
- Testing
- Thermal stimuli, Pressure stimuli, Pain ratings
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Migraine, Episodic Migraine
Real-world Prospective Study on the Use of Anti-CGRP Drugs in Migraine
The goal of this observational study is to evaluate clinical differences in patients who received preventive treatment with medication targeting calcitonin gene-related peptide (CGRP) or its receptor: monoclonal antibodies…
- Conditions
- Migraine, Episodic Migraine, Chronic Migraine, Headache
- Trial name
- EUREkA (NCT07159750)
- Testing
- CGRP antibody or gepant
- Where
- 26 sites in United States, Argentina and 11 more
- Volunteers
- 700 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Fibromyalgia (FM), Chronic Migraine Headache
Relieving Chronic Pain: Psychosomatic Mechanisms and Psychological Interventions in Fibromyalgia and Chronic Headache
Pain is one of the most important manifestations of the disease state and significantly affects people\'s quality of life. According to the International Association for the Study of Pain (IASP), pain is not only a sensory…
- Trial name
- FIBROMIG (NCT06652724)
- Testing
- Dynamic interpersonal therapy (DIT), technique of expressive writing (TSE), Treatment as Usual (TAU)
- Where
- 2 sites in Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Insomnia Chronic, Migraine Disorders
Digital CBTI for Comorbid Insomnia in Chronic Migraine
The overall aims of the study are: Aim 1: Estimate effect sizes: To estimate the effects of dCBT-I on insomnia symptoms compared to a control group (sleep hygiene education) and estimate the relationship between changes in…
- Trial name
- NCT05244889
- Testing
- Digital CBT-I, Sleep Hygiene Education
- Where
- 2 sites in United Kingdom
- Volunteers
- 88 people
- Sponsor
- University of Strathclyde
Migraine Headache
Autonomic Dysfunction in Patients With Migraine: Cardiovascular and Neurophysiology Assessment
Autonomic dysfunction in patients with migraine: cardiovascular and neurophysiology assessment.
- Trial name
- NCT06798259
- Where
- Egypt
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Migraine Headache
Electrical Stimulation of the Sphenopalatine Ganglion for the Treatment of Migraine Headaches
This investigation will gather information about a procedure called sphenopalatine ganglion (SPG) stimulation, and its appropriateness, safety, and efficacy as a treatment for those who suffer migraine headaches which may result…
- Trial name
- NCT01294046
- Testing
- Deep Brain Stimulation of SPG for Migraine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The Cleveland Clinic
Chronic Migraine Headache
Clinical Exploration of NEUROMARK System in Participants With Chronic Migraine
Clinical exploration of NEUROMARK System in Participants with Chronic Migraine
- Trial name
- NCT06862674
- Testing
- NEUROMARK System
- Where
- 7 sites in United States
- Volunteers
- 24 people
- Sponsor
- Neurent Medical
Migraine With or Without Aura, Migraine
Cooling to Alleviate Migraine #3
This is a prospective, double-blind, sham-controlled, randomized, decentralized trial. This study aims to assess the safety and efficacy of the Mi-Helper transnasal cooling device for acute treatment of migraine in an at home…
- Conditions
- Migraine With or Without Aura, Migraine, Migraine Headache
- Trial name
- CALM3 (NCT06874361)
- Testing
- Mi-Helper
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Mi-Helper, Inc.
Migraine Headache
Integrating Acupuncture Into the Management of Migraines
This research is being done to study the effect of incorporating acupuncture into the management of migraines. The primary aim is to determine in a randomized, controlled study whether individuals experiencing migraines have…
- Trial name
- NCT01481103
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- National University of Health Sciences
Tinnitus, Subjective, Tinnitus
Treatment of Tinnitus With Migraine Medications
Tinnitus represents one of the most common and distressing otologic problems, and it causes various somatic and psychological disorders that interfere with the quality of life.
- Trial name
- NCT04404439
- Testing
- Nortriptyline + Topiramate, Verapamil + Paroxetine
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of California, Irvine
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