Clinical trials: Cephalalgia
Cluster Headache
Cluster Headache Cortivazol Injection (CHCI)
the aim of tis study is to demonstrate the efficacy of cortivazol injections at the level of the greater occipital nerve to diminish the frequency of cluster headache (episodic or chronic) attacks during an active period.
- Trial name
- CHCI (NCT00804895)
- Testing
- ALTIM, cortivazol injections, PROAMP, subcutaneous serum physiological saline, Verapamil
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Migraine With Aura
Functional MRI and MRA in Migraine With Aura
Patients who report that exposure to bright light or strenuous physical activity will induce migraine aura will be provoked using one or both of these methods. Followingly the patients will be examined by functional MRI.
- Trial name
- NCT01388894
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Chronic Migraine, Tension-type Headache
Fire Needling Plus Filiform Needling for Chronic Migraine With Comorbid Tension-Type Headache
The investigators conducted a multicenter, prospective, randomized controlled clinical study to learn whether fire needling combined with filiform needling applied to pericranial muscle tenderness areas can effectively treat…
- Trial name
- NCT07633522
- Testing
- filiform needling, fire needling combined with filiform needling
- Where
- 3 sites in China
- Volunteers
- 88 people
- Sponsor
- Beijing Hospital of Traditional Chinese Medicine
Migraine Disorders
A Study Using Botulinum Toxin Type A as Headache Prophylaxis for Migraine Patients With Frequent Headaches
This is a 60 week study including a double-blind phase followed by an open-label extension phase.
- Trial name
- NCT00156910
- Testing
- Botulinum Toxin Type A
- Where
- 2 sites in United States, Canada
- Volunteers
- 679 people
- Sponsor
- Allergan
Tension-Type Headache
Comparing the Effectiveness of Dry Needling and Ischemic Compression on Tension Type Headache
Headaches are the main health problem as one of the prevalent type of all symptoms in the world population. Among different types of headaches, the most prevailing primary headache in general population is Tension-type headache…
- Trial name
- NCT05496010
- Testing
- Dry Needling and Ischemic Compression Technique
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Ziauddin University
Abdominal Pain, Chest Pain
Anchoring Patients Pain Scores in the Emergency Department
The proposed research will be a prospective, observational study to test the hypothesis that anchoring will affect verbal pain scores in the emergency department.
- Conditions
- Abdominal Pain, Chest Pain, Headache, Joint Pain
- Trial name
- NCT04717518
- Testing
- Measurement of Pain
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- CHRISTUS Health
Migraine, Overweight and Obesity
Very Low Calories Ketogenic Diet in Migraine.
Ketogenesis is a physiologic phenomenon due to starvation or ketogenic diet (KD), a drastic restricted carbohydrate dietary regimen that induces lipid metabolism and ketone body (KB) synthesis.
- Trial name
- Ketomig (NCT03076060)
- Testing
- Ketogenic diet
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- University of Roma La Sapienza
Depression, Headache
Healing Patient Rooms
Rationale: Many study reports described benefits of natural sunlight. It is believed that artificial light can achieve similar benefits as sunlight and can be used to compensate for the lack of sunlight, for instance in…
- Conditions
- Depression, Headache, Sleep
- Trial name
- NCT01504750
- Testing
- dynamic daylight and atmosphere lighting
- Where
- Netherlands
- Volunteers
- 196 people
- Sponsor
- Maastricht University Medical Center
Sleep Bruxism, Tension Headache
Treatment Sleep Bruxism With the Luco Hybrid OSA Appliance
To determine the effectiveness of the Luco Hybrid OSA Appliance in the treatment of sleep bruxism and to aid in the treatment of associated tension/migraine type headaches in adults.
- Conditions
- Sleep Bruxism, Tension Headache, Migraine Headache
- Trial name
- LucoHybrid (NCT02882880)
- Testing
- The Luco Hybrid OSA Appliance
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Luco Hybrid OSA Appliance Inc.
Migraine Disorders, Photophobia
How Can we Treat Photophobia in Migraine
Photophobia, the aberrantly increased sensitivity to light, is a common symptom in migraine patients and light discomfort is frequently found as a trigger for migraine attacks.
- Trial name
- NCT05369910
- Testing
- Light exposure (Flash), Light deprivation (Dark)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Migraine
A Placebo-Controlled Adaptive Treatment Assignment Study of Intravenous COL-144 in the Acute Treatment of Migraine
This study evaluates the efficacy of a range of intravenous doses of COL-144 in the treatment of migraine headache in order to select a dose range for further studies.
- Trial name
- NCT00384774
- Testing
- Lasmiditan
- Where
- 3 sites in Finland, Germany and 1 more
- Volunteers
- 130 people
- Sponsor
- Eli Lilly and Company
Migraine
Migraine in Poland - a Web-based Cross-sectional Survey
A survey of Polish respondents will aim to define migraine characteristics in Polish subjects. To achieve this, a structured questionnaire based mainly on American Migraine Prevalence and Prevention Study has been prepared to…
- Trial name
- MIGinPOL2021 (NCT05087420)
- Where
- 2 sites in Poland
- Volunteers
- 2,800 people
- Sponsor
- Swiat Zdrowia
Migraine
Efficacy and Tolerability of Rimegepant for the Acute Treatment of Migraine in Adults Unsuitable for Triptan Use
This study is being conducted to evaluate the efficacy and tolerability of rimegepant in a population of adults that are unsuitable for triptan medications due to a previous intolerance, lack of efficacy, or contraindication…
- Trial name
- NCT05509400
- Testing
- Rimegepant
- Where
- 93 sites in United States, Australia and 13 more
- Volunteers
- 813 people
- Sponsor
- Pfizer
Chronic Tension-Type Headache, Episodic Tension-Type Headache
Treatment of Tension Headache Using Soft Tissue Techniques VS Vagus Stimulation Techniques.
A treatment based on manual therapy and vagus nerve stimulation is more effective than manual therapy only to reduce frequency, intensity and pressure pain threshold in patients with tension type headache.
- Trial name
- NCT05097300
- Testing
- Suboccipital inhibition, Ischemic pressure, Passive stretching
- Where
- 2 sites in Spain
- Volunteers
- 42 people
- Sponsor
- Lucia Trullenque Espallargas
Migraine
Real World Effectiveness of Eptinezumab in Participants With Migraine
The purpose of this study is to examine how eptinezumab compares to other advanced preventive medications in a real-world community setting in adult participants with episodic migraine (EM) or chronic migraine (CM).
- Trial name
- EVEC (NCT05284019)
- Testing
- Eptinezumab, Erenumab, Onabotulinumtoxin-A
- Where
- 10 sites in United States
- Volunteers
- 32 people
- Sponsor
- H. Lundbeck A/S
Post-Dural Puncture Headache, Sphenopalatine Ganglion Block
Effectiveness of Sphenopalatine Ganglion Block for Post-Dural Puncture Headache
The objective of the study is to determine the effectiveness of Spheno-Palatine (SP) ganglion block to alleviate the pain of post-dural puncture headache (PDPH).
- Trial name
- NCT03430531
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Milton S. Hershey Medical Center
Migraine
Non-Invasive Neurostimulation For the Relief of Symptoms Associated With Migraine
The purpose of this pilot study is to assess feasibility and clarify the design of future study(ies) to support marketing approval of the GammaCore™ device for the treatment and/or prevention of migraine symptoms.
- Trial name
- NCT01532830
- Testing
- n-VNS
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- ElectroCore INC
Migraine
Manageable Environmental Factors in Migraine
There is limited and insufficient information on the effects of inappropriate living environments, exposure to allergens, electromagnetic fields and stress factors on the chronicity of migraine.
- Trial name
- NCT06304675
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Samsun University
Migraine
A Study Lasmiditan (LY573144) in a Single Migraine Attack in Japanese Participants With Migraine
This study will assess the efficacy and safety of lasmiditan in the acute treatment of a migraine attack in Japanese adult participants with or without aura.
- Trial name
- MONONOFU (NCT03962738)
- Testing
- Lasmiditan
- Where
- 34 sites in Japan
- Volunteers
- 846 people
- Sponsor
- Eli Lilly and Company
Headache, Tension-Type
A Pharmacokinetic Study of an Experimental Paracetamol Formulation
This PK study is designed to show bioequivalence between the study treatments.
- Trial name
- NCT01476176
- Testing
- Experimental paracetamol, Paracetamol marketed formulation
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
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