Clinical trials: Cephalalgia
Migraine Disorders, Brain
Audition After a Lesion and in Migraine. (AuditionPostLesion)
The project studies auditory processing after brain damage (in temporal and/or frontal areas) and in migraine. The auditory processes investigated are attention, short-term memory, sound-induced emotions.
- Trial name
- NCT02791997
- Testing
- Neuropsychological tests, Neurophysiological tests
- Where
- 2 sites in France
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
New Daily Persistent Headache (NDPH), New Daily Persistent Headache
New Daily Persistent Headache Survey
Purpose: to explore headache characteristics and treatment effects of patient with new daily persistent headache (NDPH) through an online survey. Research design: Online survey of patients with new daily persistent headache.
- Trial name
- NDPH (NCT05984719)
- Where
- United States
- Volunteers
- 803 people
- Sponsor
- The University of Texas Health Science Center, Houston
Healthy, Migraine
Neuropeptides in the Humane Intra- og Extracerebral Circulation.
The study aim at examining whether Sumatriptan changes the plasma values of the neuropeptides vasoactive intestinal polypeptide (VIP), calcitonin gene-related peptide (CGRP) and pituitary adenylate cyclase activating peptide…
- Trial name
- NCT00399633
- Testing
- sumatriptan
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Tension Type Headache
Desvenlafaxine for Preventive Treatment of Frequent Episodic Tension-type Headache
To evaluate whether Desvenlafaxine can reduce the frequency and severity of TTH attacks in patients.
- Trial name
- NCT07359248
- Testing
- Desvenlafaxine
- Where
- China
- Volunteers
- 432 people
- Sponsor
- Tongji Hospital
Rhinosinusitis, Headache
Effect of Low Level Laser Therapy in Patients With Chronic Rhinosinusitis.
This study aimed to evaluate the efficacy of low-level laser therapy (LLLT) for Chronic sinusitis in a randomized, double-blind, placebo-controlled trial.
- Conditions
- Rhinosinusitis, Headache, Fatigue, CT
- Trial name
- Sinusitis (NCT05861817)
- Testing
- Laser theapy
- Where
- 2 sites in Egypt
- Volunteers
- 31 people
- Sponsor
- Cairo University
Migraine, Episodic Migraine
Safety and Tolerability Study of Daily Dosing Rimegepant in Episodic Migraine Prevention
The purpose of this study is to further evaluate the long-term safety and tolerability of daily dosing of rimegepant for the prevention of episodic migraine.
- Conditions
- Migraine, Episodic Migraine, Phonophobia, Photophobia
- Trial name
- NCT05207865
- Testing
- Rimegepant
- Where
- 19 sites in United States
- Volunteers
- 441 people
- Sponsor
- Pfizer
Migraine
A Proof of Concept Alleviating the Symptoms of Photosensitive Migraine.
This proof of concept clinical study will investigate the efficacy of active lens with frame in alleviating the symptoms of migraine which are caused by photosensitivity.
- Trial name
- NCT04904328
- Testing
- Lumishade® Active Lens
- Volunteers
- 77 people
- Sponsor
- Mitsui Chemicals, Inc.
Cluster Headache
Role of Specific microRNAs in Cluster Headache
Cluster headache (CH) is a primary headache included in the trigeminal autonomic cephalalgias (TACs) according to the International Calssification of Headache Disorder, Third Edition.
- Trial name
- 5*1000 (NCT06503328)
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Migraine Headache
Auricular Acupuncture vs SOC in Migraine HA
Patients with migraine headache will be offered the opportunity to participate in this randomized study evaluating auricular acupuncture versus standard treatment for migraine headaches for patients in the pediatric emergency…
- Trial name
- MigAcu (NCT02681211)
- Testing
- Auricular Acupuncture, Ketorolac 0.5mg/kg, max 30mg, Metoclopramide 0.1 mg/kg, max 10mg
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Louisville
Migraine
Effectiveness of Auricular Acupuncture for Migraine
Migraine is a primary headache disorder characterized by recurrent episodes of moderate to severe pain, frequently accompanied by nausea, photophobia, and phonophobia.
- Trial name
- NCT07024511
- Testing
- Auricular acupuncture, Acupuncture
- Where
- 2 sites in China
- Volunteers
- 156 people
- Sponsor
- Universiti Tunku Abdul Rahman
Post-Dural Puncture Headache, Ganglion Sphenopalatine Block
The Effect of Ganglion Sphenopalatine Block (GSP-block) Follow-Up
The purpose of this study is to evaluate the long term effects of the ganglion sphenopalatine block (GSP block) on postdural puncture headache.
- Trial name
- GSP-FOLLOW (NCT05301387)
- Testing
- Ganglion Sphenopalatine Block
- Where
- Denmark
- Volunteers
- 38 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Migraine
Efficacy and Safety of Rizatriptan-Naproxen (10/550 mg) in the Acute Treatment of Migraine
A phase III study, multicenter, double-blind, double-dummy, randomized, single-dose, placebo-controlled study to evaluate the efficacy and safety of Rizatriptan-Naproxen (10/550 mg) in the acute treatment of migraine.
- Trial name
- RELIEF (NCT04384367)
- Testing
- Rizatriptan 10 mg + Naproxen 550mg, Maxalt 10Mg Tablet, Flanax 550mg
- Where
- 2 sites in Brazil
- Volunteers
- 2,068 people
- Sponsor
- Eurofarma Laboratorios S.A.
Headache, Stress (Psychology)
The Effectiveness of Acupuncture on Headaches in Women Undergoing IVF Egg Stimulation
To test the effect of acupuncture in treating headaches, as well as co-measures of stress and emotional distress, in participants during the hormonal stimulation phase prior to an oocyte retrieval.
- Conditions
- Headache, Stress (Psychology), Emotional Distress
- Trial name
- NCT07587398
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Yo San University of Traditional Chinese Medicine
Chronic Migraine Headache
Efficacy of Traditional Integrated Islamic Psychotherapy and Cognitive Behavioural Therapy for Migraine: A Randomized Controlled Trial
his randomized controlled trial aims to evaluate the efficacy of Cognitive Behavioral Therapy (CBT) and Traditional Integrated Islamic Psychotherapy (TIIP) as psychological interventions for individuals with chronic migraine.
- Trial name
- CBT TIIP (NCT07802912)
- Testing
- Cognitive Behavioral Therapy (CBT), Traditional Integrated Islamic Psychotherapy (TIIP), Medication Group
- Where
- Pakistan
- Volunteers
- 45 people
- Sponsor
- GIFT University
Cervicogenic Headache
Mobilization Versus Manipulation for the Treatment of Cervicogenic Headaches
There is currently a gap within the literature as to the effects of a thrust versus non-thrust mobilizations techniques specifically to the upper cervical spine C0-C3 along with home exercise program to help reduce frequency and…
- Trial name
- NCT03919630
- Testing
- Thrust Mobilization, Non-Thrust Mobilizations
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Franklin Pierce University
Migraine
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine
The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.
- Trial name
- PIONEER-PEDS1 (NCT04396236)
- Testing
- Lasmiditan
- Where
- 152 sites in United States, Belgium and 13 more
- Volunteers
- 847 people
- Sponsor
- Eli Lilly and Company
Episodic Migraine
Extension Study to Evaluate the Long-Term Safety and Tolerability of Oral Atogepant for the Prevention of Migraine in Participants With Episodic Migraine
The purpose of this study is to evaluate the safety and tolerability of atogepant 60 mg once a day for the prevention of migraine in participants with episodic migraine.
- Trial name
- NCT03939312
- Testing
- Atogepant
- Where
- 113 sites in United States
- Volunteers
- 685 people
- Sponsor
- Allergan
Epilepsy
Study on Migraine and Headache in Epileptic Patients
The purpose of this study is to collect data from patients who are diagnosed with epilepsy and are followed up in epilepsy clinics.
- Trial name
- NCT00642564
- Testing
- Observational study in Epileptic Patients
- Volunteers
- 955 people
- Sponsor
- Johnson & Johnson Taiwan Ltd
Headache (Migraine)
Study of Lornoxicam or Placebo for Acute Treatment of the Headache of Migraine.
To determine whether a single dose of intravenous lornoxicam is superior to intravenous placebo for the acute treatment of moderate or severe headache associated with a single migraine attack in patients with a history of…
- Trial name
- NCT00293657
- Testing
- Lornoxicam 8 mg, Lornoxicam 16 mg
- Where
- 23 sites in United States
- Volunteers
- 150 people
- Sponsor
- POZEN
Migraine
Tandem OnabotulinumtoxinA Galcanezumab Emerging Therapeutic Headache Elimination Research Study
This is a multicenter, double-blind, placebo-controlled study assessing the effectiveness of Galcanezumab as an add-on therapy for Migraine participants on a stable migraine prophylaxis regimen including Botox with or without one…
- Trial name
- TOGETHER (NCT05492695)
- Testing
- Galcanezumab
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Diamond Headache Clinic
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