Clinical trials: Cephalalgia
Migraine
Treatment of Menstrual Migraine With Sequential, Transdermal, 17-Beta-Estradiol. A Double-Blind, Randomised, Cross-Over Trial.
The purpose of this study is to determine whether transdermally administered 17-beta estradiol sequentially could reduce the number of, and severity of, menstrual migraine attacks.
- Trial name
- NCT00204074
- Testing
- 17-beta-estradiol (drug)
- Where
- Sweden
- Sponsor
- University Hospital, Linkoeping
Migraine
Efficacy and Safety of 2 Dose Regimens of TEV-48125 Versus Placebo for the Preventive Treatment of Episodic Migraine
The study is being conducted to evaluate two doses of TEV-48125 in adult patients with episodic migraine
- Trial name
- NCT02629861
- Testing
- Fremanezumab
- Where
- 275 sites in United States, Canada and 7 more
- Volunteers
- 875 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Idiopathic Intracranial Hypertension (IIH)
Tirzepatide in Idiopathic Intracranial Hypertension Trial
This will be a randomized, double-blind, parallel, placebo-controlled trial of 60 participants. The primary analysis will be a statistical comparison of the estimates of the mean difference in the 12-month change in intracranial…
- Trial name
- TIIHT (NCT07191873)
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Migraine
A Study to Assess the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
This is a double-blind, randomized, multicenter, outpatient evaluation of the safety and efficacy of elismetrep, as compared with placebo, in the treatment of moderate or severe of migraine.
- Trial name
- NCT07816367
- Testing
- Elismetrep
- Where
- 72 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- TriGemX Bio, Inc.
Postural; Defect
Assessment of Upper Cross Syndrome and Cervicogenic Headache in Smart Phone User
the purpose of this study was to assess upper cross syndrome and cervicogenic headache between addictive and non- addictive smartphone usage among university physical therapy students.
- Trial name
- NCT06690879
- Testing
- Smartphone application AI Posture Evaluation and Correction System (APECS)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jilan Adel yousef
Migraine
A Dose-Finding Study of Topiramate (JNS019) in Participants With Migraine
The purpose of this study is to determine a recommended dose of topiramate in participants with migraine (type of severe headache that occurs periodically and is often associated with nausea, vomiting, and constipation or…
- Trial name
- NCT01081795
- Testing
- Topiramate
- Where
- 29 sites in Japan
- Volunteers
- 387 people
- Sponsor
- Janssen Pharmaceutical K.K.
Chronic Headache
Combined Biofeedback With Virtual Reality in the Treatment of Pediatric Headache
The objective of the study is to examine the effect of combined treatments (biofeedback with virtual reality) for pediatric chronic headache.
- Trial name
- VR (NCT00897780)
- Testing
- Biofeedback with virtual reality
- Volunteers
- 30 people
- Sponsor
- Hadassah Medical Organization
Migraine
Zolmitriptane as Prophylaxis for Chilhood Migraine
zolmitriptane can be tried as prophylactic therapy of childhood migraine
- Trial name
- NCT06089356
- Testing
- zolmitriptanee, topiramate, Valproate
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Medication Overuse Headache, Analgesic Overuse Headache
Frovatriptan as a Transitional Therapy in Medication Overuse Headache
This study will analyze the effectiveness of a medication called Frovatriptan, in the context of medication overuse headache (MOH). MOH is a headache that develops when pain-killers are taken frequently.
- Trial name
- NCT01044251
- Testing
- Frovatriptan
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- University of Calgary
Greater Occipital Nerve, Pulsed Radiofrequency
Greater Occipital Nerve Pulsed Radiofrequency for the Treatment of Combined Migraine and Cervicogenic Headache (New Approach)
Combined migraine and cervicogenic headache present significant challenges in clinical management due to their complex and overlapping pathophysiologies.
- Trial name
- NCT06121037
- Testing
- proximal ultrasound-guided GON radiofrequency ablation, distal ultrasound-guided GON radiofrequency ablation
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Migraine, Musculoskeletal Neck Pain
Effectiveness of Multimodal Physical Therapy in Migraine
INTRODUCTION: It is very common that migraine patients could refer neck pain during or after the pain phase of migraine, suggesting that migraine pathophysiological mechanisms could be effective in activating neck pain pathways…
- Conditions
- Migraine, Musculoskeletal Neck Pain, Musculoskeletal Disorder of the Neck, Chronic Migraine
- Trial name
- MIGPHYSTREAT (NCT05226559)
- Testing
- Multimodal Physical therapy approach plus usual care, Usual care
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Neuromed IRCCS
Migraine
A Study to Evaluate the Efficacy and Safety of Eptinezumab Administered Intravenously in Participants Experiencing Acute Attack of Migraine
The purpose of this study is to evaluate the efficacy and safety of eptinezumab administered intravenously in participants experiencing an acute attack of migraine.
- Trial name
- RELIEF (NCT04152083)
- Testing
- Eptinezumab
- Where
- 57 sites in United States, Georgia
- Volunteers
- 485 people
- Sponsor
- H. Lundbeck A/S
Migraine
Safety and Efficacy Trial of MTX101 2mg for the Acute Treatment of Migraine in Adults
The goal of this clinical trial is to learn if drug MTX101 works to treat acute migraine attacks in adults. It will also learn about the safety of the drug MTX101.
- Trial name
- NCT06728553
- Testing
- MTX101
- Where
- 7 sites in United States
- Volunteers
- 78 people
- Sponsor
- Manistee Therapeutics
Migraine Disorders, Photophobia
Thin Film Spectacle Coatings to Reduce Light Sensitivity and Headaches in Child and Adolescent Patients With Migraine
The purpose of this study is to determine if a special coating, applied to the surface of glasses can reduce the frequency and severity of migraine headaches in children and adolescents.
- Trial name
- NCT01942486
- Testing
- Investigational Coating
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Utah
Headache
Prospective ED Headache Cohort Study
The purpose of this study is to determine how often headaches recur and to learn how to predict continued suffering from headache after emergency department discharge.
- Trial name
- NCT00313703
- Where
- United States
- Volunteers
- 477 people
- Sponsor
- Montefiore Medical Center
Migraine
Effect of Erenumab-aooe on Disability and Work Productivity in Employed Subjects With Episodic Migraine
To evaluate the effect of erenumab compared to placebo on disability in employed subjects with episodic migraine (EM) who have previously failed 1 or more migraine preventive treatments.
- Trial name
- NCT03912337
- Testing
- Erenumab
- Where
- 28 sites in United States
- Volunteers
- 29 people
- Sponsor
- Amgen
Headache Disorders
Effects of Multimodal Treatment of Headache in a Day Clinic Service
The observational study aims to investigate the effects of a multimodal treatment program for headache patients in a day clinic service.
- Trial name
- NCT05111873
- Testing
- multimodal treatment
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Medicine Greifswald
Migraine
A Study Evaluating the Effectiveness of PEA Compared to Placebo for Reducing Pain Severity and Duration of Migraines.
This is a double-blind randomised controlled study to evaluate the effectiveness of orally-dosed Palmitoylethanolamide (PEA) compared to placebo for reducing pain severity and duration of migraines in otherwise healthy…
- Trial name
- NCT05046522
- Testing
- Palmitoylethanolamide sold as Levagen +
- Where
- Australia
- Volunteers
- 80 people
- Sponsor
- RDC Clinical Pty Ltd
Post-Traumatic Headache, Concussion, Mild
GAIN Symptoms: Post-traumatic Headache
The overall aim of the study is to advance the knowledge on the characterization and underlying pathophysiological mechanisms of persistent post-traumatic headache (PTH) with a direct impact on the ability to diagnose and manage…
- Conditions
- Post-Traumatic Headache, Concussion, Mild, MTBI - Mild Traumatic Brain Injury
- Trial name
- NCT05857761
- Testing
- Active repetitive transcranial magnetic stimulation (rTMS)
- Where
- Denmark
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Migraine Disorders
An Open-Label Study to Evaluate the Safety of NP101 in the Treatment of Acute Migraine Over Twelve Months
This study will use an open-label design to evaluate the safety of NP101. Adult subjects who meet the enrollment criteria will be treated with NP101 (sumatriptan succinate iontophoretic transdermal patch) for acute migraine…
- Trial name
- NP101-009 (NCT00806546)
- Testing
- NP101
- Where
- 31 sites in United States
- Volunteers
- 514 people
- Sponsor
- NuPathe Inc.
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