Clinical trials: Cerebral Blood Flows
Ischemic Stroke
Glucagon-like Peptide-1 Receptor Agonists for Endovascular Stroke Thrombectomy
Endovascular thrombectomy (EVT) is a procedure that improves recovery for people who suffer from a stroke by removing blood clots from large blood vessels in the brain.
- Trial name
- LEAST (NCT07511543)
- Testing
- Semaglutide
- Volunteers
- 100 people
- Sponsor
- Population Health Research Institute
Myofascial Pain, Tension-type Headache
Blood Flow Within Active Myofascial Trigger Points Following Massage
The physiological response at the myofascial trigger point (MTrP) to massage is not known, yet would provide important objective evidence for a treatment effect and clarify the resolution process of a MTrP.
- Trial name
- NCT02389140
- Testing
- Trigger point release, Ultrasound
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Colorado, Denver
Acute Ischemic Stroke
Mechanical Thrombectomy of Acute Ischemic Stroke Anterior Circulation Distal Vessel Occlusion
Ischemic stroke continues to be of the leading causes of disability and death. Distal vessel occlusion one of most presenting and disabling varieties of ischemic stroke.
- Trial name
- NCT06427187
- Testing
- an array of devices are used in thrombectomy. These include guide catheters, stent-retrievers, microcatheters, aspiration catheters, and aspiration pump systems
- Volunteers
- 30 people
- Sponsor
- Assiut University
Migraine Without Aura
PACAP38´s (Pituitary Adenylate Cyclase-Activating Polypeptide) Headache Inducing Characteristics and Effects on the Cerebral Blood Flow
To investigate headache score and accompanying symptoms during and after infusion of PACAP38 i migraine patients
- Trial name
- NCT00380263
- Testing
- PACAP38
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Danish Headache Center
Breast Cancer
Can Exercise Training Reduce the Frequency and Severity of Hot Flushes Associated With Breast Cancer Treatment?
In brief, this study sets out to understand if exercise training can reduce the frequency and severity of hot flushes associated with breast cancer treatment.
- Trial name
- NCT03286257
- Testing
- Exercise Intervention
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Cerebral Blood Flow
A Study on Hemodynamic Relationship Including Cerebral Blood Flow Using Phase Contrast and Signal Intensity Gradient of Brain Magnetic Resonance Imaging, and Carotid Doppler Ultrasound
Cerebral blood flow measurement, which is applied to patients with cerebrovascular-related diseases, provides useful information about hemodynamic status.
- Trial name
- NCT04585971
- Testing
- Signal intensity gradient
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Chonbuk National University Hospital
Alzheimer's Disease
Cerebral and Peripheral Perfusion Pilot Study
The purpose of this study is to evaluate the hypothesis that in middle-aged, asymptomatic, adult children of persons with Alzheimer's disease (AD), atorvastatin therapy will beneficially affect mechanisms thought to contribute to…
- Trial name
- CAPP (NCT00751907)
- Testing
- atorvastatin
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Hypoxia, Endotoxemia
Cerebral Blood Flow and Metabolism During Hypoxia and Endotoxemia
The objective of the present protocol is to study whether a low level of oxygen in the blood will affect the immune response to as well as cerebral blood flow and metabolism during an infection and, conversely, whether the acute…
- Conditions
- Hypoxia, Endotoxemia, Healthy
- Trial name
- NCT00332267
- Testing
- Endotoxin infusion, Normobaric hypoxia
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Preeclampsia
Ephedrine, Phenylephrine and Metaraminol Effects on Maternal Cardiac Output, Uterine Blood Flow and Fetal Circulation
It is a prospective clinical trial with random distribution that intends to investigate maternal and fetal effects of ephedrine, phenylephrine and metaraminol during cesarean delivery in patients with pre-eclampsia.
- Trial name
- NCT02245191
- Testing
- Ephedrine, Phenylephrine, Metaraminol
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Child, Only, Essential Hypertension
Juvenile Essential Arterial Hypertension and Vascular Function
The main goal of this study is to investigate the association of the juvenile essential arterial hypertension with systemic micro- and macrovascular reactivity and cerebral vascular function, and to examine the potential impact…
- Trial name
- NCT05109013
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Neonatal Prematurity, Patent Ductus Arteriosus in Preterm Infants
Relation Between Prostaglandin E2 Metabolite Levels and the Development of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Neonates
prospective observational cohort study to explore the relationship between PGE2 metabolite levels and the development of hemodynamically significant PDA in preterm neonates.
- Conditions
- Neonatal Prematurity, Patent Ductus Arteriosus in Preterm Infants, Prostaglandins
- Trial name
- NCT07338370
- Testing
- Ibuprofen (Brufen®)
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Ain Shams University
Acute Ischemic Stroke
Safety and Efficacy Study of Remote Ischemic Conditioning Combined With Endovascular Thrombectomy for Acute Ischemic Stroke Due to Large Vessel Occlusion of Anterior Circulation
The purpose of this study is to determine the efficacy and safety of remote ischemic conditioning for patients of acute ischemic stroke who underwent endovascular thrombectomy due to large vessel occlusion of anterior circulation.
- Trial name
- NCT04977869
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 498 people
- Sponsor
- Yi Yang
Ischemic Stroke
Head Down Position for Successful Recanalization of Anterior Circulation Large Vessel Occlusion (HOPES4)
This is a prospective, randomized, open label, blinded-end point, single-center study, aiming to investigate the effect of head down position in anterior circulation large vessel occlusion patients with successful recanalization…
- Trial name
- NCT06313710
- Testing
- head down position
- Where
- China
- Volunteers
- 90 people
- Sponsor
- General Hospital of Shenyang Military Region
Tracheo Esophageal Fistula, Congenital Diaphragmatic Hernia
Cerebral Blood Flow in Neonates During Thoracoscopic Surgeries
the aim of this study is to compare the effect of different modes of mechanical ventilation by using volume-controlled ventilation and pressure-controlled ventilation on cerebral blood flow monitored by cerebral oximetry during…
- Trial name
- NCT04507295
- Testing
- cerebral oximetry ( INVOS 5100 )
- Volunteers
- 30 people
- Sponsor
- Cairo University
Stroke
Visualization of Cerebral Arteries Using Contrast-Enhanced Transcranial Ultrasound in Stroke Patients
The purpose of this study is to find out more about the usefulness of ultrasound in combination with a contrast solution to look for blood vessel blockage or occlusion in the brains of stroke patients.
- Trial name
- NCT00282841
- Testing
- ultrasound
- Where
- 2 sites in United States
- Volunteers
- 61 people
- Sponsor
- University of California, San Diego
Spinal Cord Injury
Cardiovascular, Cerebrovascular, and Cognitive Function in Spinal Cord Injury
Increased life expectancy in individuals with spinal cord injury (SCI) present clinicians with the challenge of managing the secondary complications of SCI with the chronic diseases common in an aging population.
- Trial name
- NCT02122991
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Blood Pressure, Ischemic Stroke
Comparison of Peripheral and Cerebral Arterial Flow in Acute Ischemic Stroke: Fimasartan vs. Valsartan vs. Atenolol
Confirm central blood pressure reduction effect of Fimasartan, Valsartan and Atenolol and compare correlation with the measured peripheral (central blood pressure, pulse wave velocity, and flow-mediated dilation) and cerebral…
- Trial name
- FAVOR (NCT02403349)
- Testing
- Fimasartan, Valsartan, Atenolol
- Volunteers
- 105 people
- Sponsor
- Ajou University School of Medicine
Pelvic Floor Muscle Training, Pregnancy
Examination of the Effects of Pelvic Floor Muscle Exercises on Blood Flow in Pregnant Women
This research will be conducted on pregnant volunteers who have applied to the Department of Obstetrics and Gynecology at Dokuz Eylul University Faculty of Medicine Hospital and undergone a comprehensive examination by an…
- Conditions
- Pelvic Floor Muscle Training, Pregnancy, Blood Flow Indexes
- Trial name
- Bloodflow (NCT06861335)
- Testing
- Exercise, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Cardiology, Psychiatry
Effects of Aerobic Exercise on Cognition,Cerebral Brain Flow and Mental Health Among Traumatic Brain Injury Patients
The aim of this study is to develop exercise prescription of TBI patients and then to evaluate the effectiveness of programmed aerobic walking exercise to improve cognitive performance, depression relief, motivation, symptom…
- Trial name
- NCT04243226
- Testing
- telehealth-based aerobic walking exercise
- Where
- Taiwan
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- National Defense Medical Center, Taiwan
Cerebrovascular Accident
Blood Pressure Lowering in Acute Stroke Trial (BLAST)
Patients who are suffering from a stroke often present to the hospital with elevated blood pressure. Elevated blood pressure in the setting of stroke increases the risk of brain swelling or bleeding into the brain.
- Trial name
- NCT00627991
- Testing
- Valsartan
- Where
- United States
- Sponsor
- Stanford University