Clinical trials: Cerebral Circulatory Disorder
Stroke
Saeboflex Dynamic Hand Orthosis for Inpatient Rehabilitation Stroke Patients
The purpose of this study is to determine what the potential utility of the Functional Tone Management (F.T.M) Arm Training Program using the SaeboFlex in an inpatient stroke rehabiliation hospital
- Trial name
- NCT00485641
- Testing
- SaeboFlex Dynamic Hand Orthosis, Saebo F.T.M. Arm Training Program
- Where
- 3 sites in United States
- Volunteers
- 222 people
- Sponsor
- Kessler Foundation
Stroke, Acute
FOA on Sit to Stand in Individuals Post Stroke
Focus of attention refers to what a person is thinking about during a task, with an internal focus being thinking about what one's body is doing and an external focus being thinking about a target or outcome in the environment.
- Trial name
- NCT05874661
- Testing
- External Focus of Attention, Internal Focus of Attention
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Western Carolina University
Balance Deficits, Stroke
An Engineering-Based Balance Assessment and Training Platform
This is a proposal to develop a Balanced Reach Training Protocol (BRTP) to evaluate and train dynamic standing balance. The BRTP is based upon the Balanced Reach Test (BRT) that the investigators previously developed and…
- Trial name
- BATP (NCT03994770)
- Testing
- Balanced Reach Assessment and Training Protocol
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- VA Office of Research and Development
Stroke
Physical Activity Maintenance in Stroke
It is essential that individuals living with stroke engage in physical activity to improve cardiovascular risk factors and reduce the risk of stroke (Billinger et al, 2014).
- Trial name
- NCT02681393
- Testing
- Brochure and Telephone Support, Brochure
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McMaster University
HR Vaiability, Aerobic Physical Fitness,Blood Pressure, Blood Sugar Level, Blood HDL, LDL
Aerobic Exercise Training & the Autonomic System In Patients After Myocardial Infarction or Stroke
The purpose of this study is to examine the effect of Aerobic Physical Activity on the function of the Autonomic System in patients after Myocardial Infarction or Stroke.
- Trial name
- NCT00259948
- Testing
- Aerobic exercise training
- Where
- Israel
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Cerebrovascular Stroke, Cerebral Artery Stenosis
Cerebral Autoregulation in Patients With Symptomatic Cerebral Atherosclerotic Stenosis
In this multi-center prospective observational study within a cohort of symptomatic cerebral atherosclerotic stenosis (sCAS) patients, 850 subjects were planed to be enrolled to explore the relationship between cerebral…
- Trial name
- CASCAS (NCT05028855)
- Testing
- Cerebral autoregulation assessment
- Where
- China
- Volunteers
- 850 people
- Sponsor
- Yi Yang
Stroke
Exercise Intensity Matters in Stroke Rehabilitation
The main objective of this multi-site project is to compare the effects of 12 weeks of HIIT vs. MICT on brain plasticity. The effects of HIIT vs.
- Trial name
- NCT03614585
- Testing
- 12 weeks of High-intensity Interval Training, 12 weeks of Moderate-Intensity Continuous Training
- Where
- 2 sites in Canada
- Volunteers
- 80 people
- Sponsor
- McGill University
Stroke, Cerebrovascular Disorders
Stroke Treatment Associate to Rehabilitation Therapy and Transcranial DC Stimulation
The purpose of this study is to determine whether active stimulation of the affected hemisphere will be more effective than simulated current in treatment of stroke
- Conditions
- Stroke, Cerebrovascular Disorders, Cerebral Infarction
- Trial name
- START-tDCS (NCT02156635)
- Testing
- Transcranial direct current stimulation, Constraint-Induced Movement Therapy
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of Paraíba
Foramen Ovale, Patent
Risk of Ischaemic Stroke After Pulmonary Embolism in Patients With and Without Patent Foramen Ovale
stroke's risk is increased in patients with pulmonary embolism and PFO compared to patients without PFO. Does this increased risk persist years after pulmonary embolism ?
- Trial name
- EPIC-FOPCohort (NCT04987008)
- Where
- 3 sites in France
- Volunteers
- 53 people
- Sponsor
- University Hospital, Brest
Ischemic Heart Disease, Congestive Heart Failure
Registry of Cardiovascular Disease Patients
A computerized registry of cardiovascular disease patients in a large health maintenance organization in Israel. The registry is aimed to be used by health professionals to identify cardiovascular disease patients and to follow…
- Conditions
- Ischemic Heart Disease, Congestive Heart Failure, Peripheral Vascular Disease, Cerebrovascular Disease
- Trial name
- CVD Registry (NCT01759225)
- Where
- Israel
- Volunteers
- 110,000 people
- Sponsor
- Maccabi Healthcare Services, Israel
Mitochondrial Disorders, Mitochondrial Genetic Disorders
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
The North American Mitochondrial Disease Consortium (NAMDC) maintains a patient contact registry and tissue biorepository for patients with mitochondrial disorders.
- Conditions
- Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes
- Trial name
- NAMDC (NCT01694940)
- Where
- 17 sites in United States, Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Ischemic-Hypoxic Encephalopathy
Long Term Prognostic of Neonatal Hypoxic Ischemic Encephalopathy With Hypothermia Treatment
The primary objective is to evaluate neonatal characteristics, and biological and clinical investigations as predictive factors of death, or of severe and moderate neurodevelopmental disability at 3 years, in a large…
- Trial name
- LyTONEPAL (NCT02676063)
- Where
- 22 sites in France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Grenoble
Ischemic Stroke
Amnis Therapeutics Thrombectomy Device-First in Man (FIM) Safety and Performance Study
Prospective, single-arm, open label, Safety and Performance clinical investigation.
- Trial name
- NCT02994563
- Testing
- Thrombectomy Device
- Where
- 4 sites in Spain, Sweden
- Volunteers
- 5 people
- Sponsor
- Amnis Therapeutics
Intracranial Aneurysm, Stent Embolisation
Treatment of Unruptured Intracranial Aneurysms in China
Un-ruptured intracranial aneurysm is a complex disease that seriously affects human life and health. At present, the treatment of intracranial aneurysm is divided into interventional treatment and craniotomy clipping, the two…
- Conditions
- Intracranial Aneurysm, Stent Embolisation, Craniotomy, Coil-assissted Embolisation
- Trial name
- NCT03133598
- Where
- China
- Volunteers
- 5,126 people
- Sponsor
- Zhujiang Hospital
Heart Failure
A Health Economic Evaluation of Using N-Terminal Pro Brain Natriuretic Peptide (NT-Pro BNP) in Acute Heart Failure
Cardiac biomarkers have dramatically impacted the way HF patients are evaluated and managed. In fact, the role of biomarkers has developed to better differentiate HF against other diseases and, to timely initiate and influence…
- Trial name
- NCT03669198
- Testing
- NT-Pro BNP
- Where
- Indonesia
- Volunteers
- 56 people
- Sponsor
- Heart Failure Biomarker Group
Ischemic Stroke
Hemodynamic Effects on Cerebral Autoregulation in Acute Stroke
This study investigates if there are hemodynamic alterations in acute stroke that predispose patients to impaired perfusion and regulation of cerebral blood flow.
- Trial name
- NCT02056821
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Henry Ford Health System
Stroke, Quality of Life
Association Between Fatigue Severity and Health-Related Quality of Life in Individuals With Stroke
This observational cross-sectional study aims to examine the association between fatigue severity and health-related quality of life in individuals with stroke.
- Conditions
- Stroke, Quality of Life, Post Stroke Fatigue
- Trial name
- NCT07498114
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Uskudar University
Stroke
Effect of Allium Cepa in the Management of Shoulder Pain Post Stroke
One of the disabling consequences of stroke is hemipleic shoulder pain. Hemiplegic shoulder pain could be most important hinderance to upper extremity function after stroke .
- Trial name
- NCT03468049
- Testing
- Topical App. of Allium Cepa Extract, Phonophoresis of Allium Cepa Extract, Raw Mashed Allium Cepa Application
- Where
- Nigeria
- Volunteers
- 60 people
- Sponsor
- Bayero University Kano, Nigeria
Stroke, Aphasia
Enhancing Reading Recovery in Aphasia With tDCS and Phonomotor Therapy
This study is designed for individuals with aphasia, a language disorder that affects many stroke survivors, making it difficult to read, speak, and understand language.
- Trial name
- NCT06891638
- Testing
- Schedule of tDCS administration
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Kessler Foundation
Subarachnoid Hemorrhage, Acute Kidney Injury
A Low ChloridE hyperTonic Solution for Brain Edema
This pilot study will compare the two hypertonic solutions currently used for subarachnoid hemorrhage (SAH) - related complications and to determine if the reduction of chloride load is safer, and as efficacious as the classic…
- Trial name
- ACETATE (NCT03204955)
- Testing
- Sodium chloride /sodium acetate (16.4%), Sodium chloride (23.4%), PlasmaLyte
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Emory University
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