Clinical trials: Cerebral Circulatory Disorder
Stroke Sequelae
Effect of Air Splints on Sensoriomotor Disturbances of the Affected Upper Extremity and Trunk Control in the Adult Post-stroke Patient
Objective: Sensory impairment in the affected upper limb occurs in approximately 50% of post-stroke patients and negatively impacts functional capacity and quality of life.
- Trial name
- NCT07029061
- Testing
- Air splints
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Alfonso X El Sabio University
Coronary Artery Disease, Arrhythmias, Cardiac
Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics
The etiology and specific pathogenesis of many cardiovascular diseases such as coronary atherosclerosis, cardiomyopathy, atrial fibrillation, and stroke are still unclear.
- Conditions
- Coronary Artery Disease, Arrhythmias, Cardiac, Heart Valve Diseases, Aortic Dissection
- Trial name
- PROSPECT (NCT06001073)
- Testing
- Observational; No Interventions were given.
- Where
- China
- Volunteers
- 25,000 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Obstructive Sleep Apnea, Alzheimer Disease
ENhancing Outcomes in Cognitive Impairment Through Use of Home Sleep ApNea Testing
Obstructive sleep apnea (OSA), which causes abnormal pauses in breathing during sleep, is common in patients with vascular cognitive impairment (VCI) and Alzheimer's disease (AD), and exacerbates the cognitive deficits seen in…
- Conditions
- Obstructive Sleep Apnea, Alzheimer Disease, Vascular Dementia, Mild Cognitive Impairment
- Trial name
- ENCHANT (NCT04335994)
- Testing
- In-laboratory polysomnography, Home Sleep Apnea Test
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Sunnybrook Health Sciences Centre
Ischemic Stroke
iTBS for Acute Ischemic Stroke After Thrombectomy
The goal of this randomized, single-blind, parallel-controlled clinical trial is to evaluate the efficacy and safety of intermittent theta burst stimulation (iTBS) as an adjunctive therapy for acute anterior circulation ischemic…
- Trial name
- NCT06941961
- Testing
- intermittent theta burst stimulation
- Where
- China
- Volunteers
- 178 people
- Sponsor
- Yi Yang
Stroke
Participative Rehabilitation in Stroke Patients
Primary objective of this study is to determine whether a case management of stroke patients after discharge to home or to nursing home results in improving physical and cognitive capacity one year after discharge.
- Trial name
- PaReSiS (NCT00687869)
- Testing
- Case management
- Where
- Germany
- Volunteers
- 322 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Stroke
Efficacy and Safety of Young Health Plasma on Acute Stroke
Stroke is one of the main severe disease of public health importance. Recent studies showed that old age is one of the most important factors in influencing the outcome of patients with acute stroke, and the young plasma can…
- Trial name
- NCT02913183
- Testing
- young Fresh Frozen Plasma, old Fresh Frozen Plasma
- Volunteers
- 78 people
- Sponsor
- Xinqiao Hospital of Chongqing
Stroke, Splints
Spiral Strapping for Improving Upper Limb Functions
Upper limb recovery after stroke is unacceptably poor with almost half of stroke survivors likely to regain some functional use.
- Conditions
- Stroke, Splints, Physical Disability
- Trial name
- NCT05725941
- Testing
- TogRite stretch Strapping, Traditional upper limb functional exercise training
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Umm Al-Qura University
Stroke, Sleep Wake Disorders
The SLEEPR Study: SLEep Effects on Post-stroke Rehabilitation
Sleep is critical for health and quality of life; however, little is known about the prevalence or impact of non obstructive sleep apnea (non-OSA) sleep disorders in people with stroke.
- Conditions
- Stroke, Sleep Wake Disorders, Rehabilitation, Recovery of Function
- Trial name
- SLEEPR (NCT05012605)
- Testing
- Observation
- Where
- 6 sites in United States
- Volunteers
- 200 people
- Sponsor
- State University of New York - Upstate Medical University
Fabry Disease
Treatment Protocol of Replagal for Patients With Fabry Disease
The study will evaluate the safety and efficacy of Replagal® (agalsidase alfa) at a dose of 0.2 mg/kg infused intravenously (IV) over 40 minutes, every other week.
- Trial name
- NCT01031173
- Testing
- agalsidase alfa
- Where
- 25 sites in United States
- Sponsor
- Shire
Stroke, Hypertension
Instant Message-guided Hypertension Management Intervention Among Stroke Survivors
This pilot and feasibility study aims to develop an automated instant message-delivered intervention (i.e., EMI) for hypertension management in stroke survivors, and to investigate the feasibility and effectiveness of the…
- Conditions
- Stroke, Hypertension, Lifestyle Modifications
- Trial name
- NCT06195969
- Testing
- automated instant message-guided hypertension management intervention group
- Where
- 7 sites in Hong Kong
- Volunteers
- 40 people
- Sponsor
- The University of Hong Kong
Stroke, Stroke Sequelae
A Novel Wrist Wearable Sensor System to Promote Hemiparetic Upper Extremity Use in Subacute Stroke Survivors
The proposed study is a two-arm randomized clinical trial designed to assess the effects of the StrokeWear system on clinical outcomes over a period of 6-months in subacute stroke survivors.
- Conditions
- Stroke, Stroke Sequelae, Hemiparesis;Poststroke/CVA
- Trial name
- NCT06797154
- Testing
- StrokeWear Behavioral Intervention
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Spaulding Rehabilitation Hospital
Stroke
SMART (School-aged Children Making Healthy Choices And Recognizing sTroke)
A stroke awareness program for school-aged children to learn the signs/symptoms of stroke, teach their parents and make healthy life-style choices.
- Trial name
- SMART (NCT02346266)
- Testing
- SMART Education
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Los Amigos Research and Education Institute
Stroke
Mirror Therapy After Stroke: A Dosing Study
It has been suggested that augmenting repetitive task practice with the use of box (mirror) therapy (BT) can enhance the benefits of task practice and may provide stroke survivors an opportunity to engage in self-directed…
- Trial name
- NCT02778087
- Testing
- Mirror Box Therapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Columbia University
Cerebrovascular Event, Vitamin b12
SERUM VITAMIN B12 LEVELS IN PATIENTS WITH HEMORRHAGIC VS ISCHEMIC CEREBROVASCULAR EVENT.
Cerebral vascular events (CVA) have a high prevalence in our environment; they are the first cause of disability and the second cause of death in the world (6.6 million deaths).
- Conditions
- Cerebrovascular Event, Vitamin b12, Hemorrhagic Stroke, Ischemic Stroke
- Trial name
- ViBEVC (NCT06190314)
- Testing
- Measure serum vitamin b12 levels
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Hospital General de Mexicali
Stroke, Post-Stroke Hemiparesis
Evaluation of a Wearable Exoskeleton for Functional Arm Training
The purpose of this study is to investigate how the cable-driven arm exoskeleton (CAREX) can assist task performance during 3D arm movement tasks under various experimental conditions in healthy individuals and patients with…
- Trial name
- NCT02726204
- Testing
- Gravity Elimination Alone, Path Assistance Alone, Path Assistance and Gravity Elimination
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Stroke
SURGERY VS BOTULINUM TOXIN ON QUALITY OF LIFE IN STROKE PATIENTS: RANDOMIZED TRIAL
We present a research project in the form of a controlled clinical trial with the aim of analyzing and demonstrating whether the surgical treatment of upper limb spasticity is an effective and efficient measure to improve…
- Trial name
- NCT06392633
- Testing
- spastic hand sugery, Botulinum Toxin A
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental
Turner Syndrome, Renal Insufficiency, Chronic
Study to Define Optimal IGF-1 Monitoring in Children Treated With NutropinAq
The main purpose of this study is to establish an optimal monitoring regimen in NutropinAq treated children, using newly developed capillary blood spot IGF-1 measurement technology.
- Conditions
- Turner Syndrome, Renal Insufficiency, Chronic, Pituitary Diseases, Dwarfism
- Trial name
- OPTIMA (NCT00234533)
- Testing
- Somatropin (rDNA origin)
- Where
- 45 sites in Belgium, Czechia and 12 more
- Volunteers
- 251 people
- Sponsor
- Ipsen
Stroke Patients
The Relationship of Bone Mineral Density With Balance, Functional Ambulation and Falls in Stroke Patients
The aim of this study is to investigate the relationship between bone mineral density and balance, functional ambulation and falls in hemiparetic patients with stroke in the subacute and chronic phases.
- Trial name
- NCT05207748
- Testing
- Bone mineral density
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Dementia, Alzheimer Disease
The Healthy Patterns Sleep Study
The Healthy Patterns Study intervention is a home-based activity intervention designed to improve symptoms of circadian rhythm disorders (CRD) and quality of life (QOL) in home-dwelling persons with dementia.
- Conditions
- Dementia, Alzheimer Disease, Circadian Rhythm Disorders, Circadian Rhythm Sleep Disorder
- Trial name
- NCT03682185
- Testing
- Attention-Control Condition, Timed Activity Intervention
- Where
- United States
- Volunteers
- 421 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Immune Thrombocytopenia (ITP), Acute Ischemic Stroke
Longitudinal Cohort Study on Immune Thrombocytopenia Complicated With Acute Ischemic Stroke
Immune thrombocytopenia (ITP) is an acquired bleeding disorder mediated by immune-related platelet destruction and impaired platelet production.
- Trial name
- NCT07070193
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
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