Clinical trials: Cerebral Disorder
Stroke, CVA
Acute Effects of Beetroot Juice on Locomotor Economy and Capacity in Chronic Stroke
The purpose of this study is to investigate if a beetroot juice supplement can improve oxygen capacity during walking tasks at a submaximal and maximal effort in people greater than 6 months following stroke.
- Trial name
- NCT05720013
- Testing
- Beetroot Juice supplement
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Indiana University
Auditory Perceptual Disorders, Aging Problems
Auditory Temporal Processes in Aging
Older people experience great difficulty understanding speech, especially accented English, and this problem is expected to increase with the influx of immigrants who provide services to the elderly population.
- Trial name
- NCT03468660
- Testing
- Auditory training with feedback, Listening paradigm with no feedback
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Focal Epilepsy, Transcranial Magnetis Stimulation
Transcranial Magnetic Stimulation (rTMS) for Refractory Focal Epilepsy
Epilepsy as a brain disease is characterised by enhanced brain excitability. Low frequency repetitive transcranial magnetic stimulation (rTMS) can be an effective treatment for refractory focal epilepsy.
- Trial name
- NCT06681480
- Testing
- figure-of-eight active rTMS coil device
- Where
- Slovakia
- Volunteers
- 20 people
- Sponsor
- Comenius University
Alzheimer Disease
Study of Genetic Alzheimer's Disease Mutation Carriers in Preclinical Stages of the Disease 18F-Florbetaben Positron Emission Tomography Study
The main purpose of the study is to assess safety of a single dose of FBB followed by PET scan in individuals at risk of genetic Alzheimer's disease.
- Trial name
- NCT02362880
- Testing
- Florbetaben
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Judit Pich Martínez
Stroke
Helping Stroke Patients With Movement Using Photos, Videos, and Pictograms
The goal of this interventional study is to learn how different types of visual aids-photos, videos, and pictograms-help people with stroke understand and perform simple physical movements.
- Trial name
- NCT07097779
- Testing
- Visual Aids(Photos, Videos, and Pictograms)
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Jaegyeong Lee
Transcranial Random Noise Stimulation (tRNS), Electroencephalography
Transcranial Random Noise (tRNS) for BPSD in Alzheimer's Disease: A Double-blind Randomized Controlled Trial
To investigate the treatment effect of Transcranial random noise (tRNS) on Alzheimer patients, and the underlying neural mechanism by EEG.
- Conditions
- Transcranial Random Noise Stimulation (tRNS), Electroencephalography, Alzheimer Disease, BPSD (Behavioral and Psychological Symptoms of Dementia)
- Trial name
- NCT07827196
- Testing
- High frequency transcranial random noise
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Inattention, Cognitive Training
RECOGNeyes Gaze-Control Training
RECOGNeyes is a computer game developed by members of the research team to improve attention in people who find it hard to "keep their eyes on the task".
- Conditions
- Inattention, Cognitive Training, Cognitive Control, Oculomotor Dysfunction
- Trial name
- NCT06691646
- Testing
- Gaze-control training game
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Rehabilitation, Recovery of Function
Constraint-induced Movement Therapy to Improve Gait and Mobility of People With Chronic Stroke
The purpose of this single-subject, concurrent mixed methods study is to investigate the relationship between the effect of the CIMT protocol on gait and mobility and participants' and caregivers' expectations and perceptions…
- Conditions
- Rehabilitation, Recovery of Function, Stroke, Lower Extremity Paresis
- Trial name
- NCT03114046
- Testing
- Lower extremity Constraint-induced movement therapy(LE-CIMT)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Alabama at Birmingham
Concussion, Dizziness
Physical Therapy Intervention for Extended Physical Symptoms After a Sports-related Concussion
The purpose of this study is to investigate if skilled physical therapy treatment for dizziness after sports-related concussion, delivered after greater than 30 days post-concussion is effective to remediate physical symptoms.
- Trial name
- NCT02344446
- Testing
- Skilled Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Walsh University
Migraine Without Aura
Effect of Riocigaut on Migraine Attack Induction in People With Migraine
This double-blind, randomized, placebo-controlled cross-over clinical trial aims to investigate the effects of riocigaut on migraine inducing properties in people with migraine.
- Trial name
- NCT05750446
- Testing
- Riociguat (BAY 63-2521)
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- Danish Headache Center
Oral Disease, Stroke, Ischemic
Oral Health in Patients Hospitalized Because of Ischemic Stroke
Maintaining good oral health is essential for general health and quality of life. Results of many anal-yses showed that stroke patients had poorer oral condition and worse periodontal status than control population.
- Trial name
- NCT06332846
- Testing
- oral examination
- Where
- Poland
- Volunteers
- 118 people
- Sponsor
- Pomeranian Medical University Szczecin
Headache, Migraine
Headache and Hormone Use Among Transgender Population in Thailand: A Cross-Sectional Online Study
The goal of this observational study is to learn how common headache and migraine are and to describe headache patterns among transgender adults in Thailand.
- Trial name
- H-TRANS (NCT07817446)
- Testing
- gender-affirming hormone therapy, Gender-Affirming Surgery, HIV Pre-Exposure Prophylaxis
- Where
- Thailand
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Alzheimer Disease, Neurodegenerative Diseases
Cognitive Impairment Cohort Study of the Elderly Population in YuGarden
The goal of this prospective observational research with an 8-year follow-up is to study the cognitive changes in the elderly in YuGarden community, Shanghai, China.
- Conditions
- Alzheimer Disease, Neurodegenerative Diseases, Cognitive Impairment, Mild Cognitive Impairment
- Trial name
- NCT06325527
- Where
- China
- Volunteers
- 1,872 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Atherosclerotic Cardiovascular Diseases, Cerebrovascular Diseases
Phase 1 Study of the Safety and Pharmacokinetics of YN001 With Rosuvastatin in Healthy Chinese Subjects
The primary objective of this study is to investigate the safety and tolerability of YN001 in combination with rosuvastatin, so as to provide evidence for the feasibility of YN001 combined with statins in subsequent clinical…
- Trial name
- NCT07309042
- Testing
- YN001, Rosuvastatin calcium Tablets
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Beijing Inno Medicine Co., Ltd.
Stroke, Post Stroke Seizure
Post Stroke Epileptic Seizures Risk Forecast
Improve the effectiveness of treatment and prognosis in patients with cerebrovascular accident by early detection of the risk of developing epileptic seizures.
- Conditions
- Stroke, Post Stroke Seizure, Post Stroke Epilepsy
- Trial name
- POSTER-1 (NCT03848273)
- Where
- Ukraine
- Volunteers
- 120 people
- Sponsor
- Lviv National Medical University
Atrial Fibrillation (Prevention of Stroke)
Real-Life Evidence on Stroke Prevention in SPAF
To obtain a better understanding on the comparative effectiveness of rivaroxaban and vitamin K antagonists (VKA) for stroke prevention in patients with non-valvular atrial fibrillation (SPAF) in a real-life setting
- Trial name
- RELIEF (NCT02485873)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Vitamin K antagonists
- Where
- Germany
- Volunteers
- 8,607 people
- Sponsor
- Bayer
Headache, Headache Disorders
Validity and Reliability of the Dutch HDI
The aim of our study is to investigate the validity and reliability of Dutch version of the Henry Ford Hospital Headache Disability Questionnaire (HDI).
- Conditions
- Headache, Headache Disorders, Neck Pain, Cervical Pain
- Trial name
- NCT05619354
- Testing
- Survey study
- Where
- 2 sites in Belgium
- Volunteers
- 250 people
- Sponsor
- University Ghent
Irritable Bowel Syndrome
Brain Imaging and Pain in Irritable Bowel Syndrome
This study examines the mechanisms, including brain imaging of placebo analgesia
- Trial name
- NCT00065754
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Florida
Hypopituitarism, Sleep Wake Disorders
Sleep Disorders in Hypothalamic and Pituitary Damage
Hypothalamus has a key role in multiple vital functions, including regulation of sleep-wake cycles. Oxytocin (OT), a neurohormone synthetized in the hypothalamus, has a wide range of physiological functions, including a putative…
- Conditions
- Hypopituitarism, Sleep Wake Disorders, Hypothalamic Diseases, Oxytocin Deficiency
- Trial name
- SDHPD (NCT07143266)
- Testing
- This is an observational study. No drugs will be administered
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
TBI (Traumatic Brain Injury)
Brain Development in Young Children Following Mild Traumatic Brain Injury - Pilot Study
Concussions (also known as mild traumatic brain injury) are common in young children. In some children, they can lead to short- and long-term difficulties.
- Trial name
- KAOUENN (NCT06024122)
- Testing
- IRM exam
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
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