Clinical trials: Cerebral Disorder
Traumatic Brain Injury
The Impact of Yoga-based Physical Therapy for Individuals With Traumatic Brain Injury
This study aims to explore if a yoga-based physical therapy session would promote improved (increased) heart rate variability in subjects with traumatic brain injuries.
- Trial name
- NCT03701594
- Testing
- Yoga-based physical therapy group, Seated Rest, Conventional Physical Therapy
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Shirley Ryan AbilityLab
Acute Ischemic Stroke, Stroke-Associated Pneumonia (SAP)
Oropharyngeal Flushing Suction Tube With Laryngoscope for Stroke-Associated Pneumonia
Stroke-associated pneumonia is a common and clinically important complication after acute ischemic stroke, especially in non-intubated patients with impaired consciousness and reduced cough or swallowing reflexes.
- Trial name
- OFST-SAP (NCT07647666)
- Testing
- Oropharyngeal Flushing Suction Tube, Laryngoscope-Guided Oropharyngeal Suction, Standard Suction Catheter
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Pudong New Area Gongli Hospital
Epilepsy
Mobile Application of Seizure Diary (Brain4U) in Epilepsy Care
The study is intended to evaluate the impact of mobile application on management and knowledge acquisition in patients with epilepsy.
- Trial name
- NCT04023851
- Testing
- Mobile application Brain4U
- Where
- South Korea
- Volunteers
- 119 people
- Sponsor
- Seoul National University Hospital
Regional Cerebral Blood Flow, Fecal Incontinence
Cerebral Responses During Bilateral/Unilateral Sacral Nerve Stimulation for Idiopathic Faecal Incontinence
The purpose of this study is to determine whether Sacral Nerve Stimulation (SNS) for idiopathic faecal incontinence affect cortical and deep brain activity in an acute and chronically stimulation model.
- Trial name
- NCT01095029
- Testing
- Medtronic InterStim II - 3058
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- University of Aarhus
Brain Injuries, Traumatic
Beta Blockade in in Traumatic Brain Injury
The purpose of this study is test the effect of beta-adrenergic blockade on mortality in patients with traumatic brain injury with the hypothesis being that the addition of beta blockade to the treatment regime of this patient…
- Trial name
- NCT02957331
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Tennessee
Stroke, Caregiver Burden
Efficacy and Sustainability of a Carepartner-Integrated Telerehabilitation Program for Persons With Stroke
Stroke is a leading cause of long-term disability. Research has placed little emphasis on integrating care partners (CP) (family members) into the rehabilitation process without increasing negative care partner outcomes.
- Trial name
- CARE-CITE (NCT06655402)
- Testing
- CARE-CITE, Attention Control Group, Actigraph GT3X+
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Emory University
Atrial Fibrillation
The Effect of Atrial Fibrillation Hemodynamics on Regulation of Cerebral Blood Flow
The proposed research will investigate whether the irregular effects of atrial fibrillation on the body's circulation directly impacts the regulation of cerebral blood flow.
- Trial name
- NCT00745602
- Testing
- non-invasive testing
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Parkinson's Disease
Exploration of Differences in Metabolite Concentrations by 7Teslas NMR Spectroscopy in Striatum and Subthalamic Nuclei in de Novo Parkinsonian Patients and Control Subjects
Initially, the exploration of brain metabolism by Nuclear Magnetic Resonance Spectroscopy (MRS) of the high magnetic field proton (1H) (11.7T) applied to acute and chronic animal models of Parkinson's disease (PD) showed…
- Trial name
- METABO-NGC-7T (NCT04735172)
- Testing
- specific MRI Acquisition (NMR spectroscopy) at 7T
- Where
- 2 sites in France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Stroke
VR-based Action Observation Treatment for Upper Limb Rehabilitation in Stroke: a Multimodal Study.
The loss of upper-limb motor functioning due to ischemic stroke has a negative impact on quality of life of patients. Action Observation Treatment (AOT), recently developed based on the mirror mechanism functioning, has proved…
- Trial name
- NCT05335772
- Testing
- Action Observation and following Action Execution, Landscape Observation and following Action Execution
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- CNR Institute of Neuroscience, Parma
Glioblastoma, Low Grade Glioma
Mind-Body Intervention in Glioma Couples
This trial studies how well a couple-based mind body program works in improving spiritual, psychosocial, and physical quality of life in patients with high or low grade glioma or tumors that have spread to the brain and their…
- Conditions
- Glioblastoma, Low Grade Glioma, Malignant Glioma, Metastatic Malignant Neoplasm in the Brain
- Trial name
- NCT03244995
- Testing
- Mind-Body Intervention Procedure, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Headache Disorders
Capsaicin in Treatment of Rhinogenic Headache
Description: Capsaicin (8- methyl-N-vanillyl-6-nonenamide) has been demonstrated to have a therapeutic effect in idiopathic rhinitis.
- Trial name
- NCT03330639
- Testing
- Capsaicin
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
Atrial Fibrillation, Stroke
Minimally Invasive Surgical Treatment Versus Medical Management for Stroke Patients With Atrial Fibrillation
The purpose of this study is to compare a minimally invasive surgical procedure and medication management in stroke patients with Atrial Fibrillation.
- Trial name
- NCT01442181
- Testing
- Minimally Invasive Surgery, Medical therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Florida
Pathological Gambling
Deep Low-Frequency Repetitive Transcranial Magnetic Stimulation for Cessation of Pathological Gambling
Pathological gambling (PG) is characterized by a persistent pattern of continued gambling behavior despite its adverse consequences.
- Trial name
- NCT01154712
- Testing
- Real Deep TMS
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- BeerYaakov Mental Health Center
Depression
Antidepressant Mechanisms of Transcranial Magnetic Stimulation
This study utilizes resting state fMRI, arterial spin labelling imaging, diffusion tensor imaging, structural MR-imaging, and MR-spectroscopy of GABA and Glutamate to probe the antidepressant mechanisms of repetitive transcranial…
- Trial name
- NCT02466230
- Testing
- Repetitive transcranial magnetic stimulation
- Volunteers
- 28 people
- Sponsor
- Weill Medical College of Cornell University
Migraine Headache
Cupping and Serkangabin Versus Conventional Migraine Treatment
Migraine is the most common recurrent headache. Current therapy of migraine headache consists of multiple drug groups for control of attack and prophylaxis against recurrent attacks.
- Trial name
- NCT01476930
- Testing
- cupping and serkangabin syrup, conventional migraine drug treatment
- Where
- Iran
- Volunteers
- 391 people
- Sponsor
- Birjand University of Medical Sciences
Acute Cerebral Infarction
Correlation Analysis Between Peripheral Blood PrPC Levels and Disease Severity and Prognosis in Patients With Acute Cerebral Infarction
The primary objective of this observational study is to investigate alterations in PrPc levels in peripheral blood during acute cerebral infarction, as well as the correlation between these changes and both disease severity and…
- Trial name
- NCT07513428
- Where
- China
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Jilin University
Stroke, Hemiplegia
CUped: An Approach to Motor Recovery Post-Stroke, Not Compensation
The goal of lower limb rehabilitation after stroke is recovery of independent walking at home and in the community. Few stroke survivors achieve this goal.
- Trial name
- NCT06329765
- Testing
- Exercise with CUped - a motor-assisted, split crank pedaling device and undergo 50 m of gait training.
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Marquette University
Stroke
Efficacy of a Family Telephone Intervention for Stroke
The purpose of this trial is to determine if a family intervention administered by telephone to stroke patients and their caregivers increases adaptation and functioning after stroke.
- Trial name
- NCT00031265
- Testing
- Family Intervention Telephone Tracking
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke
Nutritional Status in Subacute Stroke Patients Under Rehabilitation
Recently, is becoming more evident a relationship between malnutrition, stroke-related sarcopenia and/or altered systemic oxidative status in patients with subacute stroke .
- Trial name
- Nutristroke (NCT04923165)
- Testing
- robotic assisted intervention, biochemical analyses, BIA, hand grip
- Where
- Italy
- Volunteers
- 119 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Stroke, Equinus Deformity
Extracorporeal Shock Wave Therapy on Spastic Equinus Foot in Stroke Patients
The goal of this study is to evaluate long term effects of focused extracorporeal shock wave therapy (fESWT) on triceps surae spasticity in stroke patients according to the number of sessions applied.
- Conditions
- Stroke, Equinus Deformity, Spasticity, Muscle
- Trial name
- NCT06547684
- Testing
- fESWT
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Teresa Mateu Campos
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