Clinical trials: Cerebral Palsy Early Intervention
Cerebral Palsy
EARLY Intervention in Parent-professional Cooperation in Cerebral Palsy
Cerebral Palsy (CP) is the most common motor disability in children. It is due to damage that occurs during brain development in the fetus or infant.
- Trial name
- PRECOP (NCT06180291)
- Testing
- PRECOP program
- Where
- 8 sites in France
- Volunteers
- 66 people
- Sponsor
- Hospices Civils de Lyon
Unilateral Cerebral Palsy
Multi Sensory Stimulation And Priming (MuSSAP) in Infants at Risk of Unilateral Cerebral Palsy
A pilot randomized clinical trial exploring the effect of a Multi Sensory Stimulation And Priming (MuSSAP) training on improving manual ability in infants at risk of developing unilateral Cerebral Palsy.
- Trial name
- MuSSAP (NCT05533476)
- Testing
- Multi Sensory Stimulation and Priming, Intensive Usual Care (Upper Limb)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sint Maartenskliniek
Cerebral Palsy
GO-PLAY - Early Family-Centered Intervention for Infants With High-Risk of Cerebral Palsy
Background. Early diagnosis of cerebral palsy (CP) is important to enable appropriate intervention at a time when neuroplasticity is at its highest.
- Trial name
- GO-PLAY (NCT05883969)
- Testing
- GO-PLAY, Usual care
- Where
- 2 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Unilateral Cerebral Palsy
Implementation of Therapy Together With Early Childhood Intervention
The purpose of this project is to conduct a pilot hybrid type two implementation and efficacy study on Therapy Together with Early Childhood Intervention using an explanatory mixed methods approach to evaluate the efficacy and…
- Trial name
- NCT06853717
- Testing
- Therapy Together
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Texas Scottish Rite Hospital for Children
Perinatal Stroke
Parent Therapist Partnership to Provide Early, Intensive Exercise in Perinatal Stroke
A prospective, single blind, parallel group, randomized control trial to determine if early, intensive lower extremity activity delivered by a physical therapist and a parent in partnership improves gross motor function more than…
- Trial name
- NCT03672864
- Testing
- Intensive exercise
- Where
- 3 sites in Canada
- Volunteers
- 18 people
- Sponsor
- University of Alberta
Cerebral Palsy Children, Motor Disabilities
Implementing Powered Mobility in Early Childhood Settings for Children With Cerebral Palsy
The goal of this clinical trial is to learn if a therapist training program can help providers in Part C Early Childhood Settings use powered mobility (PM) with young children who have cerebral palsy (Gross Motor Function…
- Conditions
- Cerebral Palsy Children, Motor Disabilities, Developmental Disability, Rehabilitation
- Trial name
- NCT07220590
- Testing
- Therapist Training on Powered Mobility Implementation, Powered Mobility Intervention for Child-Caregiver Dyads
- Where
- 3 sites in United States
- Volunteers
- 70 people
- Sponsor
- Oregon Health and Science University
Cerebral Palsy, Prematurity
NEO Rehab Program for Premature Infants at Risk for Cerebral Palsy
The goal of this project is to investigate the acceptability, feasibility and fidelity of an innovative NICU rehabilitation program that will include six multimodal, gestational age (GA) appropriate, parent-administered…
- Conditions
- Cerebral Palsy, Prematurity, Early Intervention, Family Centered Care
- Trial name
- NCT04330859
- Testing
- NeoRehab Bundle, Routine care
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Virginia
Unilateral Cerebral Palsy
Wereables for Upper Limb Functionality in Hemiparesis
The project is configured as a national interventional study that aims to determine the effectiveness of an intervention strategy using wearable technology, tailored to improve function (WeFun-wearable), on the spontaneous use of…
- Trial name
- WeFun (NCT06872736)
- Testing
- WeFun-wearable activated, WeFun-wearable desactivated
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidade da Coruña
Cerebral Palsy
Cp eArly REhabilitation
The present study aims to investigate the efficacy of play-based rehabilitation delivered as usual care in children with cerebral palsy in a rehabilitation center offering both intensive and extensive care.
- Trial name
- iCARE (NCT06737471)
- Testing
- Intensive rehabilitation treatment, Extensive rehabilitation treatment
- Where
- 6 sites in Italy
- Volunteers
- 96 people
- Sponsor
- IRCCS Eugenio Medea
Preterm Infant, Cerebral Palsy
Does Timing Matter? Supporting Play, Exploration, and Early Developmental Intervention
Infants born very preterm (≤28 weeks of gestation) are at high risk of having developmental disabilities including cerebral palsy, coordination impairments, attention deficit and learning disabilities.
- Trial name
- TimeSPEEDI2 (NCT03518736)
- Testing
- Supporting Play Exploration and Developmental Intervention (SPEEDI)
- Where
- 2 sites in United States
- Volunteers
- 85 people
- Sponsor
- University of Southern California
Perinatal Stroke and Risk of Unilateral Cerebral Palsy, Early Parent-delivered Home-based Intervention
Spanish eTIPS for Early Therapy in Perinatal Stroke
This study adapts and evaluates the Spanish version of eTIPS, an early home-based therapy program for infants at risk of unilateral cerebral palsy after perinatal stroke.
- Conditions
- Perinatal Stroke and Risk of Unilateral Cerebral Palsy, Early Parent-delivered Home-based Intervention, Spanish Cross-cultural Adaptation of eTIPS
- Trial name
- eTIPS-ES (NCT07605988)
- Testing
- eTIPS, Usual Clinical Care
- Volunteers
- 20 people
- Sponsor
- University of Castilla-La Mancha
Cerebral Palsy, Hypoxic-Ischemic Encephalopathy
Early Virtual Intervention for Infants With CP Following HIE Diagnosis
This will be a five year study that will be a prospective, randomized, controlled trial (RCT) to assess the effect of a virtual early intervention care delivery model in the provision of therapy to enhance the neurodevelopmental…
- Conditions
- Cerebral Palsy, Hypoxic-Ischemic Encephalopathy, Brain Injuries, Perinatal Hypoxia
- Trial name
- RECOVER (NCT04913324)
- Testing
- Virtual Care
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- The Hospital for Sick Children
Disorder of Speech and Language Development
Language and Motor Skills of Preterm Infants in Pre-school Age: Diagnosis and Early Intervention
The preterm children have more difficulty minor neurological developmental than the general population even without cerebral palsy. Their oral language difficulties of language and writing have been little studied.
- Trial name
- LAMOPRESCO (NCT01426659)
- Testing
- parental stimulation according to protocol
- Where
- 6 sites in France
- Volunteers
- 139 people
- Sponsor
- University Hospital, Rouen
Infants at Risk of Cerebral Palsy
A Randomized Controlled Trial of Hybrid Environmental Enrichment-Based Early Intervention in Infants at Risk of Cerebral Palsy
This randomized controlled trial aims to evaluate the effects of a hybrid environmental enrichment-based early intervention grounded in the Homeostasis-Enrichment-Plasticity (HEP®) Approach in infants at risk of cerebral palsy…
- Trial name
- NCT07116148
- Testing
- HEP-Based Early Intervention, Conventional Early Intervention
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Medipol University
Cerebral Palsy
CareToy Early Intervention in Infants at Risk for Cerebral Palsy
Cerebral Palsy (CP), due to pre-perinatal brain lesions, is a main cause of childhood disabilities with high cost for individuals and society.
- Trial name
- NCT03234959
- Testing
- CareToy intervention, Infant Massage
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- IRCCS Fondazione Stella Maris
Preterm, Sensory Disorders
Evaluation of The Effectiveness of The SAFE Early Intervention Program
In this study, it was aimed to examine the effect of SAFE, which is a sensory-based, activity-oriented early intervention approach applied in an enriched environment with family cooperation, on cognitive, language, motor and…
- Conditions
- Preterm, Sensory Disorders, Cerebral Palsy
- Trial name
- NCT06930482
- Testing
- Safe early intervention, early intervention approach based on neurodevelopmental treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Gazi University
Cerebral Palsy
CP-EDIT: Cerebral Palsy - Early Diagnosis and Intervention Trial
Background. Early diagnosis of cerebral palsy is important as intervention becomes possible at a time where neuroplasticity is at the highest. Current mean age at diagnosis is 13 months in Denmark.
- Trial name
- CP-EDIT (NCT05835674)
- Testing
- Early intervention program
- Where
- 4 sites in Denmark
- Volunteers
- 500 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Premature, Developmental Disability
Explorer Babies Early Intervention Program
Premature babies have a high risk of adverse developmental outcomes. Early intervention approaches are applied to reduce these adverse outcomes or support of developmental delay.
- Conditions
- Premature, Developmental Disability, Cerebral Palsy, Motor Disorders
- Trial name
- NCT04203589
- Testing
- The Explorer Baby Early Intervention Program, Neurodevelopmental Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Cerebral Palsy
Implementation of Early Detection and Early Intervention Service Delivery in Infants at Risk for Cerebral Palsy to Promote Infants' Psychomotor Development and Maternal Health
The BORNTOGETTHERE consists of improving health programs for early detection and surveillance of Cerebral Palsy (CP) by implementing the first International Clinical Practice Guidelines (Novak et al, 2017) in multiple sites in…
- Trial name
- BornTogether (NCT04622787)
- Testing
- Knowledge translation
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- University of Pisa
Cerebral Palsy
Early Intervention in Infants With Cerebral Palsy
Contractures are a frequent cause of reduced mobility in children with Cerebral palsy (CP) already at the age of 2-3 years. Reduced muscle use and muscle growth have been suggested as key factors in the development of…
- Trial name
- CONTRACT (NCT04250454)
- Testing
- CONTRACT
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- University of Copenhagen