Clinical trials: Cerebral Saturation
Perfusion Index and Cerebral NIRS Trends in Low Cardiac Output Syndrome
Can Perfusion Index and Cerebral Oxygen Saturation Trends Predict Low Cardiac Output in Pediatric Cardiovascular Surgeries
In this prospective, observational study, we aim to investigate whether routinely monitored Perfusion Index (PI) and cerebral oxygen saturation (NIRS) values in pediatric patients aged 0-6 undergoing congenital heart surgery are…
- Trial name
- NCT06759506
- Volunteers
- 40 people
- Sponsor
- Bozyaka Training and Research Hospital
Cerebral Oxygen Saturation During Spinal Anesthesia for Cesarean Delivery
Spinal Anesthesia for Cesarean Delivery is Associated With Decreases in Regional Cerebral Oxygen Saturation as Assessed by Near- Infrared Spectroscopy
The cerebral oxygen saturation is assessed by means of near-infrared spectometry in parturients undergoing cesarean delivery under spinal anesthesia.
- Trial name
- NCT01669135
- Testing
- Spinal Anesthesia with cerebral oxygen saturation monitoring
- Where
- Greece
- Volunteers
- 34 people
- Sponsor
- University of Athens
Brain Monitor, Anaesthesia
Evaluation of the BRAINDEX Brain Monitor in Cardiac Surgery, Interventional Comparative Study
The main objective of this study is to show the concordance of the SctO2 values of the ARGOS platform with the standard SctO2 values (comparative study with platform INVOS, Medtronic).
- Trial name
- ARGOS Platform (NCT06594198)
- Testing
- Cerebral monitor
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Braindex
Epilepsy
Pre-oxygenation and Measures of Gas Exchanges During Seizures in the Epilepsy Monitoring Unit
The primary goal of the study is to assess the effect of pre-oxygenation on oxygen and carbon dioxide levels during seizures in patients admitted at the Epilepsy Monitoring Unit (EMU).
- Trial name
- NCT02241798
- Testing
- oxygen
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- NYU Langone Health
Diabetes Mellitus (D003920), Cardiac Surgical Procedures (D006348)
Cerebral-tissue Oxygen Balance Affected by Diabetes Mellitus
The brain has high oxygen extraction, thus the regional cerebral tissue oxygen saturation (rSO2) is lower than the central venous oxygen saturation (ScvO2).
- Conditions
- Diabetes Mellitus (D003920), Cardiac Surgical Procedures (D006348), Near-Infrared (D019265)
- Trial name
- NCT03668301
- Volunteers
- 148 people
- Sponsor
- Szeged University
Brain Ischemia Hypoxia, Muscle; Ischemic
Multisite Tissue Oxygenation Guided Perioperative Care in Cardiac Surgery
The BOTTOMLINE-CS trial is an international, open, single-center, pragmatic, randomised controlled trial to investigate whether multisite tissue oxygen saturation monitoring-guided perioperative care reduces composite…
- Conditions
- Brain Ischemia Hypoxia, Muscle; Ischemic, Muscle Hypoxia
- Trial name
- BOTTOMLINECS (NCT04896736)
- Testing
- Multisite tissue oxygenation-guided care, Usual care
- Where
- China
- Volunteers
- 1,960 people
- Sponsor
- Yale University
Pulmonary Surgical Procedures, Recovery Period
Oxygen Peripheral Saturations and Lung Surgery
The purpose of this study is to compare the ability of two peripheral and non invasive devices to detect hypoxic events during one-lung ventilation and during the early postoperative period.
- Trial name
- NCT01255033
- Testing
- Monitoring of tissular oxygenation
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Hopital Foch
Thyroidectomy, Near-infrared Spectroscopy
Near Infrared Spectroscopy in Thyroidectomy
Thyroidectomy operations have traditionally been performed as open surgery. However, the scarring that occurs in the patient leads to cosmetic problems, especially in young women.
- Trial name
- NCT04186715
- Testing
- Near-infrared spectroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Antalya Training and Research Hospital
Anxiety
Effect of Different Doses of Dexmedetomidine on Cerebral Oxygen Saturation and Postoperative Anxiety in Elderly Patients
To investigate the effect of different doses of dexmedetomidine on Cerebral Oxygen Saturation and Postoperative anxiety in elderly patients undergoing laparoscopic surgery
- Trial name
- NCT05640427
- Testing
- Dexmedetomidine, normal saline
- Where
- China
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Qinhuangdao
Prematurity; Extreme
Use of NIRS in Preterm Population Born at Altitude
Near-infrared spectroscopy (NIRS), is a technology that can provide continuous, non-invasive monitoring of oxygenation in tissue.
- Trial name
- NCT04639583
- Testing
- Near-infrared spectroscopy (NIRS) utilization
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of New Mexico
Cardiac Disease, Cognitive Dysfunction
Cerebral Oxygen Saturation Monitoring In Cardiac Surgery (COSMICS)
Neurological dysfunction continues to be one of the complications of considerable concern in patients undergoing cardiac surgery.
- Trial name
- COSMICS (NCT04766554)
- Testing
- Cerebral oximetry monitor (The INVOS® Cerebral/Somatic Oximeter) and protocol-based interventions
- Where
- 2 sites in Brazil
- Volunteers
- 326 people
- Sponsor
- Instituto Nacional de Cardiologia de Laranjeiras
Oxygen Saturation
Cerebral Oxygenation to Guide Supplemental Oxygen
Objective: Objective of this pilot feasibility study is to monitor crSO2 using NIRS INVOS 5100 (Somanetics, USA) in addition to SpO2 monitoring to guide supplemental oxygen delivery and respiratory support based on both…
- Trial name
- COSGOD (NCT02017691)
- Testing
- Near Infrared Spectroscopy, Pulse-oximetry
- Where
- 2 sites in Austria, Canada
- Volunteers
- 60 people
- Sponsor
- Medical University of Graz
Cerebral Oxygen Saturation
The Effects of Demographic and Clinical Data of Patients on Cerebral Oxygen Monitoring Values
The aim of this study is to examine the effects of patients' clinical and demographic datas on cerebral oxygen saturation values. Brain oxygenation is measured using near infrared spectroscopy (NIRS).
- Trial name
- NCT07228546
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Tuna Şahin
Acute Kidney Injury
Renal Oxygen Saturation During Off-pump Coronary Artery Bypass Graft Surgery
The purpose of this study is to evaluate changes in renal oxygen saturation (rrSO2) and its relationship with central venous oxygen saturation (cvSO2), cerebral cortical oxygen saturation (rcSO2), and hemodynamic parameters while…
- Trial name
- OPCAB (NCT04679337)
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Yeungnam University College of Medicine
Anaesthesia
Measuring the Effect of External Pressure on the Regional Cerebral Oxygen Saturation Monitored by Near-infrared Spectroscopy(NIRS) Technology
During general anaesthesia, to ensure sufficient oxygen supply to the brain, the NIRS technology can be used. It consist of two sensors placed on the forehead, and measures the oxygen saturation of the tissue underneath the…
- Trial name
- NCT01971996
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Blood Transfusion, Cardiac Surgery
Brain Tissue Oxygen Saturation and Blood Transfusion in Cardiac Surgery
In cardiac operations under cardiopulmonary bypass(CPB), monitoring of brain tissue oxygen saturation with infrared spectrophotoscopy leads to a reduction of the number of packed red cell(PRC) transfusions during the period of…
- Trial name
- INVOS (NCT00879463)
- Testing
- Brain tissue oxygen saturation monitoring, Transfusion according to the anesthesiologist's judgement
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- Larissa University Hospital
Anemia
Effect of Arterial Oxygen Partial Pressure on Mixed Venous Oxygen Saturation
Mixed venous oxygen saturation is known to reflect oxygen delivery and, thus, is frequently monitored in patients undergoing cardiac surgery.
- Trial name
- NCT04144205
- Testing
- Change of the fraction of inspired oxygen
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Oxygen Deficiency
Comparison of Oxygen Reserve Index and Regional Cerebral Oxygen Saturation Indetermining Hypoxia in Obese Patients
The primary aim of this study is to compare the effectiveness of ORI and rcSO2 in predicting hypoxia early in obese patients who are sensitive to hypoxia.
- Trial name
- NCT06404151
- Testing
- monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Cerebral Desaturation Events, Spine Surgeries
Mg Sulfate Versus Dexmedetomidine on Cerebral Oxygen Saturation
This study is to evaluate the effects of dexmedetomidine and magnesium sulfate on cerebral oxygen saturation in patients undergoing spine surgeries as adjuvant to general anesthesia guided by cerebral oximetry.
- Trial name
- mg/dex/rSO2 (NCT06848595)
- Testing
- spine surgery, Magnesium sulfate, Dexmedetomidine
- Volunteers
- 90 people
- Sponsor
- Tanta University
Anesthesia; Functional
Assessment Through Transcutaneous Brain Oximetry (NIRS) of Two Preoxygenation Techniques
Preoxygenation techniques is currently considered a standard of care, but how they influence cerebral oxygenation remains largely unknown.
- Trial name
- NCT04352049
- Testing
- Preoxygenation
- Where
- 2 sites in Spain
- Volunteers
- 53 people
- Sponsor
- Complexo Hospitalario Universitario de A Coruña