Clinical trials: Cerebral Saturation
Cerebral Oxygen Saturation
Changes of Cerebral Oxygenation During Anesthesia Induction
The aim of this study was to investigate the changes of cerebral oxygen saturation (rSO2) during anesthesia induction.
- Trial name
- NCT02687334
- Testing
- 100% Oxygen
- Where
- China
- Volunteers
- 33 people
- Sponsor
- China Medical University, China
Pediatric Congenital Heart Surgery
Predictive Value of the FORE-SIGHT™ Monitor for Hemodynamic Deterioration
The postoperative period after congenital heart surgery in children can be a very critical episode, where it is of utmost importance to closely monitor the circulation in these patients.
- Trial name
- NCT01706497
- Testing
- Cerebral tissue oxygen saturation monitoring, blinded
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- KU Leuven
Glioblastoma Multiforme, Glycolytic Index
Biologic Association Between Metabolic Magnetic Resonance-positron Emission Tomograph (MR-PET) and Tissue Measures of Glycolysis in Brain Tumors of Infiltrating Glioblastoma Cells
The purpose of this project is to validate a new combined MRI and PET imaging technique as a biomarker or measure of glycolysis in brain tumors.
- Conditions
- Glioblastoma Multiforme, Glycolytic Index, Epidermal Growth Factor Receptor
- Trial name
- NCT06059690
- Testing
- pH Measurement of in vivo tissue
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Oxygen Saturation
Comparison of Volatile Anesthetics on Cerebral Oxygenation During Controlled Hypotension
Controlled hypotension is a preferred method for reducing surgical bleeding during septoplasty operations however, the level of hypotension and bradycardia should not disrupt cerebral oxygenation.
- Trial name
- NCT02834845
- Testing
- Sevoflurane, Desflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- Ufuk University
Pre-Term
Cerebral Oxygen Saturation Monitoring During Optimum Cord Management in Preterm Infants
This study will assess the feasibilty measuring cerebral oxygen saturations using a Near Infrared Spectroscopy (NIRS) monitor immediately after delivery of preterm infants.
- Trial name
- COSMIC (NCT06526091)
- Testing
- Cerebral NIRS monitoring at delivery
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Imperial College Healthcare NHS Trust
Pediatric Liver Transplantation, Developmental Delay
Intraoperative Cerebral and Renal Tissue Oxygen Saturation and Pediatric Living Donor Liver Transplantation Prognosis.
This rSO2 study is a prospective clinical study. The purpose of the rSO2 study is to investigate whether there is a correlation between the intraoperative cerebral and renal tissue oxygen saturation and the incidence of…
- Conditions
- Pediatric Liver Transplantation, Developmental Delay, Postoperative Complications, Socioemotional Delay
- Trial name
- rSO2-LDLT (NCT04518332)
- Where
- China
- Volunteers
- 123 people
- Sponsor
- RenJi Hospital
Heart Arrest
Comparison of Cerebral SctO2 Between 36℃ and 33℃ of TTM After Cardiac Arrest
The investigators hypothesize that 1. if decrease in SctO2 level is caused by the degree of hypothermia, SctO2 level in the 33-TH may be lower than that in the 36-TH group. 2.
- Trial name
- NCT02889744
- Testing
- Arctic Sun
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Seoul National University Hospital
Cholecyctitis
Regional Cerebral Oxygen Saturation in Laparoscopic Surgery
While few studies have determined the optimal intra-abdominal CO2 insufflation pressure to achieve optimal surgical condition during LCs with deep-NMB and moderate-NMB in laparoscopic cholecystectomy (LC), previous studies…
- Trial name
- NCT02436954
- Testing
- CO2 insufflation at intra-abdominal pressure 8 mmHg, CO2 insufflation at intra-abdominal pressure 12 mmHg
- Volunteers
- 40 people
- Sponsor
- Konkuk University Medical Center
Intermittent Hypoxemia, Apnea of Prematurity
Influence of Oxygen Target Range on Intermittent Hypoxemia in Preterm Infants
In this randomized crossover trial, preterm infants with intermittent hypoxemia and need for supplemental oxygen will be randomized to either Sequence of two different oxygen target ranges (low: 85-89%; high: 91-95%) for a total…
- Trial name
- NCT02743988
- Testing
- Oxygen
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- University of Ulm
Brain Injuries
Invasive and Non-Invasive Assessment of Cerebral Oxygenation in Patients With Severe Traumatic Brain Injury (TBI)
The purpose of this study is to investigate the relationship among regional transcranial oxygen saturation (rSO2), brain tissue oxygen pressure (PbtO2) and cerebral perfusion pressure (CPP) in patients with severe traumatic brain…
- Trial name
- NCT00703495
- Testing
- transcranial oxygen saturation measurement (INVOS Somanetics 5100C)
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Brain Metastases, Brain Metastases, Adult
Developing a New MRI Technique to Understand Changes in Brain Tumors After Treatment
The purpose of this study is to develop and test a new magnetic resonance imaging (MRI) technique to see if it can be used to tell the difference between tumor growth from worsening of cancer and growth from the effects of…
- Conditions
- Brain Metastases, Brain Metastases, Adult, Metastatic Brain Tumor, Metastatic Brain Cancer
- Trial name
- NCT05559853
- Testing
- CEST-MRF
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Craniosynostoses
CraNIRS Clinical Study
Craniosynostosis is a rare disorder characterized by a premature fusion of one or more sutures of the skull. Craniosynostosis is usually diagnosed in the first years of life.
- Trial name
- CraNIRS (NCT04086056)
- Testing
- NIRS monitoring
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Post-induction Hypotension, Eadyn
The Relationship Between Hypotension and Tissue O2 in Invasive Eadyn During Anesthesia Induction in Open Heart Surgery
Our aim is to identify patients who may experience hypotension during anesthesia induction. Intraoperative hemodynamic stability plays an important role in tissue oxygenation.
- Conditions
- Post-induction Hypotension, Eadyn, Cerebral and Kidney Regional Saturation, Open Heart Surgery
- Trial name
- Eadyn (NCT07831252)
- Testing
- mostcare hemodynamic monitor, Masimo NIRS, Hemodynamic Measurements on Standart Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Haseki Training and Research Hospital
Pneumoperitoneum
Effect of Pneumoperitoneum on Cognitive Function and Regional Cerebral Oxygen Saturation
The investigators hypothesized that the pneumoperitoneum with reverse Trendelenburg position could alter the rSO2 and early postoperative cognitive function.
- Trial name
- rSO2pneumo (NCT01826955)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Gachon University Gil Medical Center
Cerebral Hypoxia During and/or Resulting From A Procedure
The Effects of Body Mass İndex On İntraabdominal Pressure And Regional Cerebral Oxygen Saturation İn Prone Position
A total of 40 ASA (American Society of Anesthesiology) physical status I-III who underwent lumbar disc hernia repair for one or two levels were included in this prospective study.
- Trial name
- NCT05392478
- Volunteers
- 40 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Postoperative Cognitive Dysfunction
Optic Nerve Sheath Diameter and Postoperative Cognitive Disfunction at Laparoscopic Surgery
Purpose: Pneumoperitoneum during laparoscopic abdominal surgery increases intra-abdominal pressure (IAP), potentially altering intracranial pressure (ICP) and cerebral oxygenation, with unclear implications for early…
- Trial name
- NCT07264764
- Testing
- Optic nerve sheath diameter (ONSD)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Duzce University
Etiology of Hyperlactathemia, Early Period After Cardiopulmonary Bypass Surgery
NEW MONITORING IN DIFFERENTIAL DIAGNOSIS OF HYPERLACTATHEMIA IN CARDIOPULMONARY BYPASS SURGERY
Objective: The objective of the study was to investigate a reverse correlation between blood lactate levels and rSO2, and distinguish between hypoxic and non-hypoxic hyperlactatemia seen in the early postoperative period.
- Conditions
- Etiology of Hyperlactathemia, Early Period After Cardiopulmonary Bypass Surgery, Washout Phenomenon
- Trial name
- NCT04706884
- Testing
- Near infrared spectroscopy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Acibadem University
Alzheimer Disease
Detecting Early Alzheimer's Using MR
Alzheimer's disease (AD) is the most common cause of dementia, affecting approximately 10% of individuals aged ≥ 65. Most available treatments aim at controlling symptoms at an early stage rather than providing a cure.
- Trial name
- DREAMER (NCT05614310)
- Testing
- Magnetic Resonance Imaging (MRI), Blood Glucose Assessment, Positron Emission Tomography (PET)
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Nephrectomy
Changes of Right and Left Cerebral Oxygen Saturation and Blood Flow During Nephrectomy in Lateral Decubitus Position
The purpose of this study is to determine changes of right and left cerebral oxygen saturation and blood flow during nephrectomy in lateral decubitus position.
- Trial name
- NCT01101490
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
Post-Operative Confusion
Braindex Cerebral Tissue Oxygen Saturation (SctO2) Measurement Algorithm Assessment and Improvement
The objective of this clinical trial is to optimize Braindex brain tissue oxygen saturation (SctO2) measurement algorithm compared to a mixed reference value of jugular venous and systemic arterial saturation, during proven…
- Trial name
- POC-SctO2 (NCT05897060)
- Testing
- Venus Jugular O2 Saturation optical fiber
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Braindex