Clinical trials: Cerebral Stroke
Delayed Cerebral Ischemia After Subarachnoid Hemorrhage, Ischemic Stroke of Large or Medium Vessels
Thrombo-inflammation in Acute Neurovascular Diseases: Definition of New Therapeutic Targets (TARGETS)
The objective of this observational study is to compare the relative concentrations of various thrombo-inflammatory markers at different follow-up time points in: patients with or without delayed cerebral ischemia after…
- Trial name
- NCT07354321
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- François Delvoye
Functional Electrical Stimulation
Effect of Functional Electrical Stimulation on Hand Functions in Stroke Patients
Background: Hand dysfunction is one of the most disabling consequences of stroke and significantly limits independence in activities of daily living.
- Trial name
- NCT07456293
- Testing
- functional electrical stimulation, Conventional physiotherapy
- Where
- 2 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Carotid Artery Diseases, Stroke
Clinical and Laboratory Biomarkers in Patients With Atherothrombotic Stroke
Aim of the present study is to investigate molecular and clinical markers in patients with atherosclerotic carotid stenosis (ACAS) in the ischemic stroke acute phase.
- Trial name
- CLAST (NCT02450721)
- Testing
- Biomarkers serum level measurement
- Where
- Russia
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- St. Petersburg State Pavlov Medical University
Family Caregivers, Stroke
Telehealth Assessment and Skill-Building Intervention for Stroke Caregivers (TASK III)
Caring for a family member after a stroke can be very difficult and worsen the physical and mental health of untrained caregivers.
- Trial name
- NCT05304078
- Testing
- Telehealth Assessment and Skill-Building Kit (TASK III) Group, Information Support and Referral (ISR) Group
- Where
- United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Cerebrovascular Disease, Stroke
Remote Ischemic Limb Preconditioning In Healthy Volunteers
The investigators would like to determine if remote ischemic leg preconditioning in healthy volunteers improves cerebral vasomotor reactivity as measured by breath holding and transcranial doppler vasomotor reactivity.
- Trial name
- NCT02553655
- Testing
- 4x 5min Limb Preconditioning, 3x 10min Limb Preconditioning
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cerebrovascular Accident, Moyamoya Disease
Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya Disease and Stroke Patients
Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya disease and stroke patients
- Trial name
- NCT01419275
- Testing
- Xenon contrast agent, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Stanford University
Stroke, fMRI
fMRI Neurofeedback for Motor Rehabilitation
Background: People can learn to use feedback about brain activity to change that activity. Researchers want to see if people who have had a stroke can change their brain activity by practice and thought with feedback, and if that…
- Trial name
- NCT02089776
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
MACE, Cardiac Death
Real-World Cohort Study of Cardiopulmonary Function in Chinese Patients With Cardiovascular Disease: CPET Evaluation and Five-Year Prognostic Follow-Up Based on a Multicenter Structured Data Platform
The goal of this observational study is to observe the characteristics of cardiopulmonary exercise testing (CPET) parameters in patients across different cardiovascular diseases and to evaluate the predictive value of…
- Conditions
- MACE, Cardiac Death, Unplanned Repeat Revascularization, Cardiac Rehospitalization
- Trial name
- China-CPET (NCT07130968)
- Where
- China
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Stroke, Cerebrovascular Disorders
Home-based Cognitive Strategy Training for Daily Living in Adults With Chronic Stroke
This pilot experimental study aims to describe the feasibility of a cognitive strategy training protocol : PRPP-I, in activities of daily life across home-based setting for adults with chronic stroke for improvement of…
- Trial name
- PRPP-HOME (NCT07084025)
- Testing
- Perceive, Recall, Plan and Perform-Intervention protocol (PRPP-I)
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Stroke, Hemiparesis;Poststroke/CVA
Muscle Oxygenation and Spasticity in Hemiparetic Stroke Patients
Conditions such as hemiparesis, sensory and motor impairment, perceptual impairment, cognitive impairment, aphasia, and dysphagia may be observed after stroke.
- Conditions
- Stroke, Hemiparesis;Poststroke/CVA, Spasticity as Sequela of Stroke
- Trial name
- NCT06362954
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Family Caregivers, Stroke
Caregiver Self-Management Needs Through Skill-Building
Caring for a family member after a stroke can be very difficult and worsen the physical and mental health of untrained caregivers.
- Trial name
- NCT03635151
- Testing
- Telephone Assessment and Skill-Building Kit (TASK III) Group, Information Support and Referral (ISR) Group
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Ischemic Stroke
REcurrent Stroke Prevention Through Personalized Education by Clinical Trainers (RESPPECT Trial)
This a single blind randomized control study comparing standard of care for nursing hospital discharge education versus same with an additional experimental enhanced educational intervention.
- Trial name
- RESPPECT (NCT03861494)
- Testing
- Enhanced Stroke Education, Usual Stroke Education
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Washington Regional Medical Center
Stroke
SMARTCap Stroke Study: A Field Deployable Blood Test for Stroke
The hypothesis is that a stroke causes release of purines from brain into blood and that this is a very early biomarker of brain ischaemia.
- Trial name
- SMARTCAP (NCT02308605)
- Testing
- SMARTCap
- Where
- 2 sites in United Kingdom
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Functional Disability, Dementia
Aspirin in Reducing Events in the Elderly
ASPREE-XT is a post-treatment, longitudinal observational follow-up study of ASPREE participants [ASPREE Investigator Group, 2013; www.aspree.org; McNeil et al 2017].
- Conditions
- Functional Disability, Dementia, Heart Disease, Stroke
- Trial name
- ASPREE (NCT01038583)
- Testing
- 100 mg enteric-coated aspirin
- Where
- 47 sites in United States, Australia
- Volunteers
- 19,114 people, healthy volunteers welcome
- Sponsor
- Hennepin Healthcare Research Institute
Stroke, Split-belt Treadmill
Optimizing Gait Symmetry After Stroke Using Mechanical Constraints and Sensory Feedback
This single-session study aims to evaluate a novel gait training protocol that integrates mechanical constraints and sensory feedback to enhance paretic leg propulsion in individuals post-stroke.
- Conditions
- Stroke, Split-belt Treadmill, Resistance Exercise, Feedback
- Trial name
- NCT07087769
- Testing
- Treadmill Walking with Split-Belt and/or Tied-Belt Conditions, Mechanical Resistance (Pelvis and/or Ankle) depending on participant's walking capacity, Sensory Feedback Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Carotid Atherosclerosis, Cerebrovascular Accident
Potential Risk Factors for Stroke
Early studies have shown that the immune system may play a role in the development of strokes. Conditions such as high blood pressure, high cholesterol, diabetes, and old age can activate the immune system and increase the risk…
- Conditions
- Carotid Atherosclerosis, Cerebrovascular Accident, Diabetes Mellitus, Hypercholesterolemia
- Trial name
- NCT00001368
- Testing
- cytokine and leukocyte activation profile
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Rehabilitation of Upper Limb Motor Function in Hemiplegia Due to Supratentorial Cerebral Infarction Using Armeo Power Robot
Effects of Armeo Power Robot Therapy on Upper Limb Recovery in Hemiplegic Stroke Patients
This study investigates the effectiveness of combining Armeo Power robotic therapy with conventional rehabilitation techniques to improve upper limb motor function in patients with hemiplegia caused by supratentorial cerebral…
- Trial name
- BV108/RAPPHCN (NCT06708065)
- Testing
- Armeo Power robot restores upper limb motor function., A Home Exercise Program, Occupational therapy activities
- Where
- Vietnam
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Hanoi Medical University
Stroke, Cramp
The Application of Wide Pulse High Frequency Neuromuscular Electrical Stimulation in Disorders Associated With Motoneuron Hyperexcitability
In the present project, the investigators aim at proposing innovative ways of investigating spinal motoneuron hyperexcitability to counteract the associated impairments by using wide pulse high frequency neuromuscular electrical…
- Conditions
- Stroke, Cramp, Restless Legs Syndrome, Healthy Volunteers
- Trial name
- MnHyperex (NCT05908214)
- Testing
- wide pulse high frequency neuromuscular electrical stimulation training
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Embolic Stroke of Undetermined Source
Identification of New Markers of Atrial Myopathy in Patients With Embolic Stroke of Undetermined Source (ESUS) From MRI 4D Data
Atrial myopathy is considered to be the underlying cause of a large proportion of embolic strokes of undetermined source. However, the definition of this atrial condition is not well delineated while its identification could lead…
- Trial name
- IRM 4D-AVC (NCT04717843)
- Testing
- 4D Flow MRI, Medical consultation with 12 leads ECG, Holter ECG
- Where
- 3 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Hypertension, Stroke (CVA) or TIA
Effectiveness of BP Remote Monitoring With Virtual Physician Management in Hypertensive Patients.
To assess the feasibility and adoptability of DailyDoctor's remote monitoring clinical decision support software tool in helping physicians virtually manage systolic blood pressures among patients with history of stroke or TIA to…
- Trial name
- NCT05319418
- Testing
- Daily Blood Pressure Monitoring
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- AIRx Health, Inc.
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