Clinical trials: Cerebral Vascular Accident
Heart Arrest, Out-Of-Hospital, Computed Tomography
Head Computed Tomography for Predicting Neurological Outcome After Cardiac Arrest
The European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) joint guidelines for post-resuscitation care recommend a multimodal approach to prognostication of neurological outcome.
- Conditions
- Heart Arrest, Out-Of-Hospital, Computed Tomography, Unconsciousness, Neurologic Deficits
- Trial name
- NCT03913065
- Testing
- CT
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Lund University
Coronary Artery Disease, Chest Syndrome
CT Stress Myocardial Perfusion, Fractional Flow Reserve and Angiography in Patients With Stable Chest Pain Syndromes
The purpose of the DYNAMITE trial (Dynamic CT stress myocardial perfusion, CT fractional flow reserve (FFR-CT) and coronary CT angiography for optimized treatment strategy in patients with chest pain syndromes) is to determine…
- Conditions
- Coronary Artery Disease, Chest Syndrome, Acute Myocardial Infarction, Heart Failure
- Trial name
- DYNAMITE (NCT04709900)
- Testing
- CT angiography, FFR-CT and stress CT myocardial perfusion
- Where
- Denmark
- Volunteers
- 2,000 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Stroke, Hemiplegic Gait
Gait Analysis of Hemiparetics Adults Patients With Quadripod Cane and Rolling Cane
After stroke, a lot of patients present an hemiparesis and gait disorders. They need walking aids like quadripod cane or rolling cane.
- Trial name
- NCT05163444
- Testing
- Gait analysis with rolling cane, Gait analysis with quadripod cane
- Where
- 2 sites in Belgium
- Volunteers
- 30 people
- Sponsor
- University of Liege
Stroke
tDCS Immediate Effect on Cardiorespiratory Parameters in Hemiparetics Adults Patients Due to Stroke.
Previous studies found important function of brain in exercises regulation on healthy and athlete patients and this studies showed not invasive stimulation on temporal cortex brain, induces electrics field to insula cortex, in…
- Trial name
- NCT02398344
- Testing
- tDCS active
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Nove de Julho
Cerebrovascular Accident (CVA), Stroke
Evaluating the Indego Exoskeleton for Persons With Hemiplegia Due to CVA
The purpose of this study is to evaluate the safety and effectiveness of the Indego exoskeleton as a gait training tool for individuals with hemiplegia due to Cerebrovascular Accident (CVA).
- Conditions
- Cerebrovascular Accident (CVA), Stroke, Hemiplegia
- Trial name
- NCT03054064
- Testing
- Indego Exoskeleton
- Where
- 7 sites in United States
- Volunteers
- 48 people
- Sponsor
- Parker Hannifin Corporation
Stroke
Effect of Thoracic Manual Therapy in Hemiplegic Patients
Neurological problems both lead to many respiratory problems primarily and events secondary to neurological diseases or symptoms can be the cause of respiratory failure.
- Trial name
- NCT04503499
- Testing
- Manuel Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Istinye University
TBI Traumatic Brain Injury, CVA (Cerebrovascular Accident)
Efficacy and Safety of 6Degrees MyMove Interactive Virtual Reality Compared to Passive Virtual Reality in Subacute Stroke and Traumatic Brain Injury Rehabilitation: A Randomized Controlled Trial
Stroke and traumatic brain injury frequently result in persistent upper and lower limb motor impairment. While conventional rehabilitation improves outcomes, patient adherence and training intensity remain limiting factors.
- Trial name
- NCT07441798
- Testing
- MyMove/VR system, Passive VR
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Reuth Rehabilitation Hospital
Stroke
Clinical Predictors of Rehabilitation-induced Arm Recovery After Stroke: Longitudinal Cohort Study
Clinical predictors of rehabilitation-induced arm recovery after stroke are still missing since literature provides evidence mainly on the spontaneous recovery path.
- Trial name
- NeuroPro (NCT05423119)
- Testing
- conventional therapy
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Cognitive Decline, Intracerebral Hemorrhage
Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial (TRIDENT) Cognitive Sub-Study
A Sub-Study of an investigator initiated and conducted, multicentre, international, double-blinded, placebo-controlled, parallel-group, randomised controlled trial (TRIDENT) to determine the effect of more intensive long-term…
- Conditions
- Cognitive Decline, Intracerebral Hemorrhage, Dementia, Vascular, Cerebral Small Vessel Diseases
- Trial name
- TRIDENT COG (NCT03785067)
- Testing
- telmisartan 20mg + amlodipine 2.5mg +indapamide 1.25mg
- Where
- 4 sites in Australia, Netherlands
- Volunteers
- 1 people
- Sponsor
- The George Institute
Sickle Cell Anemia
Transcranial Doppler (TCD) With Transfusions Changing to Hydroxyurea
The primary goal of the Phase III TWiTCH trial is to compare 24 months of alternative therapy (hydroxyurea) to standard therapy (transfusions) for pediatric subjects with sickle cell anemia and abnormally high (≥200 cm/sec)…
- Trial name
- TWiTCH (NCT01425307)
- Testing
- Hydroxyurea
- Volunteers
- 159 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Acute Ischaemic Middle Cerebral Artery Stroke
A Study to Evaluate the Efficacy and Safety of Piracetam on Aphasia After Acute Ischemic Cerebral Artery Stroke
The aim of this study was to confirm the efficacy of piracetam after 12 weeks of treatment on the aphasic status of subjects suffering from aphasia after acute ischemic middle cerebral artery stroke and having received their…
- Trial name
- NCT01883011
- Testing
- Piracetam
- Where
- 44 sites in Argentina, Austria and 13 more
- Volunteers
- 571 people
- Sponsor
- UCB S.A. - Pharma Sector
Cardiovascular Disease
Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine
SEARCH is a randomised, double-blind, multi-centre United Kingdom (UK) trial of 12,064 patients with myocardial infarction (MI) prior to study entry which aims to demonstrate whether a more intensive cholesterol lowering regimen…
- Trial name
- SEARCH (NCT00124072)
- Testing
- Simvastatin 20 mg daily, Folic acid 2 mg + vitamin B12 1 mg daily, Simvastatin 80 mg daily
- Where
- United Kingdom
- Volunteers
- 12,064 people
- Sponsor
- University of Oxford
Stroke
Exploring the Efficacy of Combined Task-Specific and Cognitive Strategy Training in Subacute Stroke
Novel stroke rehabilitation approaches, such as task-specific training (TST), have shown promise in improving stroke recovery components such as basic mobility and activities of daily living; however, evidence suggests these…
- Trial name
- NCT01309165
- Testing
- CO-OP, Standard Occupational Therapy
- Where
- 2 sites in United States, Canada
- Volunteers
- 35 people
- Sponsor
- St. John's Rehab Hospital
Perinatal Brain Injury
Neuro-MoD: Neuroplasticity With Motor Development
This study is for infants and toddlers between 8 and 24 months old who use one arm and/or hand differently following a perinatal brain injury.
- Trial name
- NCT07738432
- Testing
- Constraint-Induced Movement Therapy (CIMT), Transcutaneous auricular vagus nerve stimulation (taVNS)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Wisconsin, Madison
Ischemic Stroke
POSITIVE Stroke Clinical Trial
Primary Endpoint: The primary objective is to show that AIS patients, ineligible for or refractory to treatment with IV-tPA, with appropriate image selection, treated with mechanical thrombectomy within 6-12 hours of symptom…
- Trial name
- NCT01852201
- Testing
- Endovascular Mechanical Thrombectomy
- Where
- 20 sites in United States
- Volunteers
- 33 people
- Sponsor
- Medical University of South Carolina
Occlusive Stroke
SURE 18 Registry -Asahi Chikai Black 18 in LVO Stroke
The objective of this study is to obtain post market data on the Asahi Chikai Black 18 neurovascular guidewire in the treatment of intracranial large vessel occlusive stroke.
- Trial name
- NCT03438565
- Testing
- Asahi Chikai Black 18 neurovascular guidewire
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Stroke, Aortic Valve Stenosis
Acute STROke Complicating TAVI - Management and Outcomes
Periprocedural complications of trans catheter aortic valve implantation, and particularly the occurrence of stroke has a marked impact on survival and quality of life.
- Conditions
- Stroke, Aortic Valve Stenosis, Periprocedural Complication
- Trial name
- ASTRO-TAVI (NCT05241821)
- Testing
- Mechanical thrombectomy, Thrombolytic Agent
- Where
- Israel
- Volunteers
- 484 people
- Sponsor
- Rabin Medical Center
Ischemic Stroke
Safety/Feasibility of Autologous Mononuclear Bone Marrow Cells in Stroke Patients
The purpose of this research study is to find out if bone marrow treatment (bone marrow aspiration and infusion of stem cells) can be safely used in adults who have recently (within 24-72 hours)suffered an acute ischemic stroke.
- Trial name
- NCT00859014
- Testing
- Autologous Bone Marrow Mononuclear Cells
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- The University of Texas Health Science Center, Houston
Stroke
"Evaluation Of ALBA® Device for Upper Extremity Motor Function In Adults With Subacute And Chronic Acquired Brain Injury"
As part of the rehabilitation techniques, robotic equipment has been introduced for the rehabilitation of the upper extremity with promising results.
- Trial name
- NCT05824416
- Testing
- Experimental: ALBA, Conventional Therapy
- Where
- Chile
- Volunteers
- 32 people
- Sponsor
- uMov
Ischemic Stroke
Efficacy of Virtual Reality Exercises in STroke Rehabilitation: A Multicentre Study (EVREST Multicentre)
A multicentre, randomized, two parallel group study comparing virtual reality using Wii gaming technology versus Recreational activities in patients receiving conventional rehabilitation after an ischemic stroke.
- Trial name
- NCT01406912
- Testing
- Recreational Activity, Wii Gaming System Arm
- Where
- 13 sites in Argentina, Brazil and 3 more
- Volunteers
- 141 people
- Sponsor
- Unity Health Toronto
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